Depressive Disorder, Major
"Depressive Disorder, Major" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.
Descriptor ID |
D003865
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MeSH Number(s) |
F03.600.300.375
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Concept/Terms |
Depressive Disorder, Major- Depressive Disorder, Major
- Depressive Disorders, Major
- Disorder, Major Depressive
- Disorders, Major Depressive
- Major Depressive Disorders
- Major Depressive Disorder
Depression, Involutional- Depression, Involutional
- Involutional Depression
- Melancholia, Involutional
- Involutional Melancholia
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Below are MeSH descriptors whose meaning is more general than "Depressive Disorder, Major".
Below are MeSH descriptors whose meaning is more specific than "Depressive Disorder, Major".
This graph shows the total number of publications written about "Depressive Disorder, Major" by people in UAMS Profiles by year, and whether "Depressive Disorder, Major" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2022 | 3 | 0 | 3 | 2021 | 10 | 0 | 10 | 2020 | 0 | 2 | 2 | 2019 | 7 | 1 | 8 | 2018 | 8 | 0 | 8 | 2017 | 7 | 2 | 9 | 2016 | 4 | 0 | 4 | 2015 | 6 | 1 | 7 | 2014 | 6 | 1 | 7 | 2013 | 5 | 2 | 7 | 2012 | 6 | 4 | 10 | 2011 | 1 | 1 | 2 | 2010 | 4 | 0 | 4 | 2009 | 4 | 0 | 4 | 2008 | 2 | 1 | 3 | 2007 | 2 | 1 | 3 | 2006 | 6 | 0 | 6 | 2005 | 12 | 0 | 12 | 2004 | 3 | 0 | 3 | 2003 | 8 | 0 | 8 | 2002 | 4 | 0 | 4 | 2001 | 1 | 0 | 1 | 2000 | 3 | 2 | 5 | 1999 | 2 | 0 | 2 |
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Below are the most recent publications written about "Depressive Disorder, Major" by people in Profiles over the past ten years.
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Oslin DW, Lynch KG, Shih MC, Ingram EP, Wray LO, Chapman SR, Kranzler HR, Gelernter J, Pyne JM, Stone A, DuVall SL, Lehmann LS, Thase ME, Aslam M, Batki SL, Bjork JM, Blow FC, Brenner LA, Chen P, Desai S, Dieperink EW, Fears SC, Fuller MA, Goodman CS, Graham DP, Haas GL, Hamner MB, Helstrom AW, Hurley RA, Icardi MS, Jurjus GJ, Kilbourne AM, Kreyenbuhl J, Lache DJ, Lieske SP, Lynch JA, Meyer LJ, Montalvo C, Muralidhar S, Ostacher MJ, Paschall GY, Pfeiffer PN, Prieto S, Przygodzki RM, Ranganathan M, Rodriguez-Suarez MM, Roggenkamp H, Schichman SA, Schneeweis JS, Simonetti JA, Steinhauer SR, Suppes T, Umbert MA, Vassy JL, Voora D, Wiechers IR, Wood AE. Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial. JAMA. 2022 07 12; 328(2):151-161.
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Brydges CR, Bhattacharyya S, Dehkordi SM, Milaneschi Y, Penninx B, Jansen R, Kristal BS, Han X, Arnold M, Kastenmüller G, Bekhbat M, Mayberg HS, Craighead WE, Rush AJ, Fiehn O, Dunlop BW, Kaddurah-Daouk R. Metabolomic and inflammatory signatures of symptom dimensions in major depression. Brain Behav Immun. 2022 05; 102:42-52.
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Katz IR, Rogers MP, Lew R, Thwin SS, Doros G, Ahearn E, Ostacher MJ, DeLisi LE, Smith EG, Ringer RJ, Ferguson R, Hoffman B, Kaufman JS, Paik JM, Conrad CH, Holmberg EF, Boney TY, Huang GD, Liang MH. Lithium Treatment in the Prevention of Repeat Suicide-Related Outcomes in Veterans With Major Depression or Bipolar Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2022 01 01; 79(1):24-32.
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Kim DJ, Mirmina J, Narine S, Wachtel J, Carbajal JM, Fox H, Cáceda R. Altered physical pain processing in different psychiatric conditions. Neurosci Biobehav Rev. 2022 02; 133:104510.
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Pilunthanakul T, Goh TJ, Fung DSS, Sultana R, Allen JC, Sung M. Validity of the patient health questionnaire 9-item in autistic youths: a pilot study. BMC Psychiatry. 2021 11 12; 21(1):564.
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Arathimos R, Ronaldson A, Howe LJ, Fabbri C, Hagenaars S, Hotopf M, Gaughran F, Lewis CM, Dregan A. Vitamin D and the risk of treatment-resistant and atypical depression: A Mendelian randomization study. Transl Psychiatry. 2021 11 04; 11(1):561.
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Watson KT, Simard JF, Henderson VW, Nutkiewicz L, Lamers F, Nasca C, Rasgon N, Penninx BWJH. Incident Major Depressive Disorder Predicted by Three Measures of Insulin Resistance: A Dutch Cohort Study. Am J Psychiatry. 2021 10 01; 178(10):914-920.
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Kalra SS, Jaber J, Alzghoul BN, Hyde R, Parikh S, Urbine D, Reddy R. Pre-Existing Psychiatric Illness Is Associated With an Increased Risk of Delirium in Patients With Acute Respiratory Distress Syndrome. J Intensive Care Med. 2022 May; 37(5):647-654.
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Wang X, Eichhorn J, Haq I, Baghal A. Resting-state brain metabolic fingerprinting clusters (biomarkers) and predictive models for major depression in multiple myeloma patients. PLoS One. 2021; 16(5):e0251026.
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Watson KT, Simard JF, Henderson VW, Nutkiewicz L, Lamers F, Rasgon N, Penninx B. Association of Insulin Resistance With Depression Severity and Remission Status: Defining a Metabolic Endophenotype of Depression. JAMA Psychiatry. 2021 04 01; 78(4):439-441.
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MahmoudianDehkordi S, Ahmed AT, Bhattacharyya S, Han X, Baillie RA, Arnold M, Skime MK, John-Williams LS, Moseley MA, Thompson JW, Louie G, Riva-Posse P, Craighead WE, McDonald W, Krishnan R, Rush AJ, Frye MA, Dunlop BW, Weinshilboum RM, Kaddurah-Daouk R. Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression. Transl Psychiatry. 2021 03 02; 11(1):153.
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Rosoff DB, Smith GD, Lohoff FW. Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis. JAMA Psychiatry. 2021 02 01; 78(2):151-160.
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Ramsey CM, Lynch KG, Thase ME, Gelernter J, Kranzler HR, Pyne JM, Shih MC, Stone A, Oslin DW. Prevalence of predicted gene-drug interactions for antidepressants in the treatment of major depressive disorder in the Precision Medicine in Mental Health Care Study. J Affect Disord. 2021 03 01; 282:1272-1277.
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Worley LLM, Wise-Ehlers A. Telepsychiatry in Obstetrics. Obstet Gynecol Clin North Am. 2020 Jun; 47(2):333-340.
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Hayes CJ, Krebs EE, Hudson T, Brown J, Li C, Martin BC. Impact of opioid dose escalation on pain intensity: a retrospective cohort study. Pain. 2020 05; 161(5):979-988.
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Cohen BM. Evidence-Based Drug Treatment of Acute Depression in Bipolar Disorder. JAMA Psychiatry. 2019 12 01; 76(12):1314-1315.
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Jain N, Wan F, Kothari M, Adelodun A, Ware J, Sarode R, Hedayati SS. Association of platelet function with depression and its treatment with sertraline in patients with chronic kidney disease: analysis of a randomized trial. BMC Nephrol. 2019 10 29; 20(1):395.
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Trapp NT, Uitermarkt B, King Johnson M, Koscik TR, Garrett L, Heinzerling A, Zanaty M, Holland MT, Howard M, Boes AD. A new device to improve target localization for transcranial magnetic stimulation therapy. Brain Stimul. 2019 Nov - Dec; 12(6):1600-1602.
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Bhattacharyya S, Ahmed AT, Arnold M, Liu D, Luo C, Zhu H, Mahmoudiandehkordi S, Neavin D, Louie G, Dunlop BW, Frye MA, Wang L, Weinshilboum RM, Krishnan RR, Rush AJ, Kaddurah-Daouk R. Metabolomic signature of exposure and response to citalopram/escitalopram in depressed outpatients. Transl Psychiatry. 2019 07 04; 9(1):173.
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Subica AM, Aitaoto N, Link BG, Yamada AM, Henwood BF, Sullivan G. Mental Health Status, Need, and Unmet Need for Mental Health Services Among U.S. Pacific Islanders. Psychiatr Serv. 2019 07 01; 70(7):578-585.
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Sanmartin MX, Ali MM, Chen J, Dwyer DS. Mental Health Treatment and Unmet Mental Health Care Need Among Pregnant Women With Major Depressive Episode in the United States. Psychiatr Serv. 2019 06 01; 70(6):503-506.
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Goldberg SB, Simpson TL, Lehavot K, Katon JG, Chen JA, Glass JE, Schnurr PP, Sayer NA, Fortney JC. Mental Health Treatment Delay: A Comparison Among Civilians and Veterans of Different Service Eras. Psychiatr Serv. 2019 05 01; 70(5):358-366.
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Messias E, Flynn V. Burnout and Depression: Same Phenomenon or Overlapping Constructs? Response to Bianchi et al. Am J Psychiatry. 2019 01 01; 176(1):79-80.
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Jollant F, Voegeli G, Kordsmeier NC, Carbajal JM, Richard-Devantoy S, Turecki G, Cáceda R. A visual analog scale to measure psychological and physical pain: A preliminary validation of the PPP-VAS in two independent samples of depressed patients. Prog Neuropsychopharmacol Biol Psychiatry. 2019 03 02; 90:55-61.
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Messias E, Flynn V. The Tired, Retired, and Recovered Physician: Professional Burnout Versus Major Depressive Disorder. Am J Psychiatry. 2018 08 01; 175(8):716-719.
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Gustafsson HC, Goodman SH, Feng T, Choi J, Lee S, Newport DJ, Knight B, Pingeton B, Stowe ZN, Monk C. Major depressive disorder during pregnancy: Psychiatric medications have minimal effects on the fetus and infant yet development is compromised. Dev Psychopathol. 2018 08; 30(3):773-785.
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Zubenko GS, Sommer BR, Cohen BM. On the Marketing and Use of Pharmacogenetic Tests for Psychiatric Treatment. JAMA Psychiatry. 2018 08 01; 75(8):769-770.
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Yang Y, Zhao H, Boomsma DI, Ligthart L, Belin AC, Smith GD, Esko T, Freilinger TM, Hansen TF, Ikram MA, Kallela M, Kubisch C, Paraskevi C, Strachan DP, Wessman M, van den Maagdenberg AMJM, Terwindt GM, Nyholt DR. Molecular genetic overlap between migraine and major depressive disorder. Eur J Hum Genet. 2018 08; 26(8):1202-1216.
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Cáceda R, Bush K, James GA, Stowe ZN, Kilts CD. Modes of Resting Functional Brain Organization Differentiate Suicidal Thoughts and Actions: A Preliminary Study. J Clin Psychiatry. 2018 07 10; 79(4).
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Bovin MJ, Miller CJ, Koenig CJ, Lipschitz JM, Zamora KA, Wright PB, Pyne JM, Burgess JF. Veterans' experiences initiating VA-based mental health care. Psychol Serv. 2019 Nov; 16(4):612-620.
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Kumar P, Goer F, Murray L, Dillon DG, Beltzer ML, Cohen AL, Brooks NH, Pizzagalli DA. Impaired reward prediction error encoding and striatal-midbrain connectivity in depression. Neuropsychopharmacology. 2018 06; 43(7):1581-1588.
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Hedayati SS, Gregg LP, Carmody T, Jain N, Toups M, Rush AJ, Toto RD, Trivedi MH. Effect of Sertraline on Depressive Symptoms in Patients With Chronic Kidney Disease Without Dialysis Dependence: The CAST Randomized Clinical Trial. JAMA. 2017 11 21; 318(19):1876-1890.
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Shwartz SK, Morris RD, Penna S. Psychometric properties of the Saint Louis University Mental Status Examination. Appl Neuropsychol Adult. 2019 Mar-Apr; 26(2):101-110.
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Suri R, Stowe ZN, Cohen LS, Newport DJ, Burt VK, Aquino-Elias AR, Knight BT, Mintz J, Altshuler LL. Prospective Longitudinal Study of Predictors of Postpartum-Onset Depression in Women With a History of Major Depressive Disorder. J Clin Psychiatry. 2017 Sep/Oct; 78(8):1110-1116.
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Phillips C. Brain-Derived Neurotrophic Factor, Depression, and Physical Activity: Making the Neuroplastic Connection. Neural Plast. 2017; 2017:7260130.
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Ramaker RC, Bowling KM, Lasseigne BN, Hagenauer MH, Hardigan AA, Davis NS, Gertz J, Cartagena PM, Walsh DM, Vawter MP, Jones EG, Schatzberg AF, Barchas JD, Watson SJ, Bunney BG, Akil H, Bunney WE, Li JZ, Cooper SJ, Myers RM. Post-mortem molecular profiling of three psychiatric disorders. Genome Med. 2017 07 28; 9(1):72.
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Coker JL, Tripathi SP, Knight BT, Pennell PB, Magann EF, Newport DJ, Stowe ZN. Rating scale item assessment of self-harm in postpartum women: a cross-sectional analysis. Arch Womens Ment Health. 2017 10; 20(5):687-694.
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Peyre H, Hoertel N, Stordeur C, Lebeau G, Blanco C, McMahon K, Basmaci R, Lemogne C, Limosin F, Delorme R. Contributing Factors and Mental Health Outcomes of First Suicide Attempt During Childhood and Adolescence: Results From a Nationally Representative Study. J Clin Psychiatry. 2017 Jun; 78(6):e622-e630.
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Hudson TJ, Painter JT, Martin BC, Austen MA, Williams JS, Fortney JC, Sullivan MD, Edlund MJ. Pharmacoepidemiologic analyses of opioid use among OEF/OIF/OND veterans. Pain. 2017 06; 158(6):1039-1045.
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Phillips C. Physical Activity Modulates Common Neuroplasticity Substrates in Major Depressive and Bipolar Disorder. Neural Plast. 2017; 2017:7014146.
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Jain N, Carmody T, Minhajuddin AT, Toups M, Trivedi MH, Rush AJ, Hedayati SS. Prognostic Utility of a Self-Reported Depression Questionnaire versus Clinician-Based Assessment on Renal Outcomes. Am J Nephrol. 2016; 44(3):234-44.
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Campbell DG, Bonner LM, Bolkan CR, Lanto AB, Zivin K, Waltz TJ, Klap R, Rubenstein LV, Chaney EF. Stigma Predicts Treatment Preferences and Care Engagement Among Veterans Affairs Primary Care Patients with Depression. Ann Behav Med. 2016 08; 50(4):533-44.
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Chua TE, Allen JC, Ang L, Ong LL, Ch'ng YC, Chen H. Patterns and predictors of treatment outcome for antenatal major depression. Singapore Med J. 2017 Nov; 58(11):642-648.
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Chouinard VA, Pingali SM, Chouinard G, Henderson DC, Mallya SG, Cypess AM, Cohen BM, Öngür D. Factors associated with overweight and obesity in schizophrenia, schizoaffective and bipolar disorders. Psychiatry Res. 2016 Mar 30; 237:304-10.
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Wo NK, Guyitt B, Owen R. Cognitive Behavioral Therapy as a Treatment for Electroconvulsive Therapy Phobia: Case Report and Review of Literature. J ECT. 2015 Dec; 31(4):273-6.
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Weinstein JJ, Rogers BP, Taylor WD, Boyd BD, Cowan RL, Shelton KM, Salomon RM. Effects of acute tryptophan depletion on raphé functional connectivity in depression. Psychiatry Res. 2015 Nov 30; 234(2):164-71.
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Helton SG, Lohoff FW. Pharmacogenetics of alcohol use disorders and comorbid psychiatric disorders. Psychiatry Res. 2015 Dec 15; 230(2):121-9.
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Emslie GJ, Wells TG, Prakash A, Zhang Q, Pangallo BA, Bangs ME, March JS. Acute and longer-term safety results from a pooled analysis of duloxetine studies for the treatment of children and adolescents with major depressive disorder. J Child Adolesc Psychopharmacol. 2015 May; 25(4):293-305.
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Roley ME, Claycomb MA, Contractor AA, Dranger P, Armour C, Elhai JD. The relationship between rumination, PTSD, and depression symptoms. J Affect Disord. 2015 Jul 15; 180:116-21.
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Dow AL, Lin TV, Chartoff EH, Potter D, McPhie DL, Van't Veer AV, Knoll AT, Lee KN, Neve RL, Patel TB, Ongur D, Cohen BM, Carlezon WA. Sprouty2 in the dorsal hippocampus regulates neurogenesis and stress responsiveness in rats. PLoS One. 2015; 10(3):e0120693.
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Helton SG, Lohoff FW. Serotonin pathway polymorphisms and the treatment of major depressive disorder and anxiety disorders. Pharmacogenomics. 2015; 16(5):541-53.
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Zvolensky MJ, Bakhshaie J, Sheffer C, Perez A, Goodwin RD. Major depressive disorder and smoking relapse among adults in the United States: a 10-year, prospective investigation. Psychiatry Res. 2015 Mar 30; 226(1):73-7.
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Ghasemi M, Phillips C, Trillo L, De Miguel Z, Das D, Salehi A. The role of NMDA receptors in the pathophysiology and treatment of mood disorders. Neurosci Biobehav Rev. 2014 Nov; 47:336-58.
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Zubenko GS, Hughes HB, Jordan RM, Lyons-Weiler J, Cohen BM. Differential hippocampal gene expression and pathway analysis in an etiology-based mouse model of major depressive disorder. Am J Med Genet B Neuropsychiatr Genet. 2014 Sep; 165B(6):457-66.
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Benson BE, Willis MW, Ketter TA, Speer A, Kimbrell TA, Herscovitch P, George MS, Post RM. Differential abnormalities of functional connectivity of the amygdala and hippocampus in unipolar and bipolar affective disorders. J Affect Disord. 2014 Oct; 168:243-53.
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Jerrell JM, McIntyre RS, Park YM. Risk factors for incident major depressive disorder in children and adolescents with attention-deficit/hyperactivity disorder. Eur Child Adolesc Psychiatry. 2015 Jan; 24(1):65-73.
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Rubio JM, Olfson M, Pérez-Fuentes G, Garcia-Toro M, Wang S, Blanco C. Effect of first episode axis I disorders on quality of life. J Nerv Ment Dis. 2014 Apr; 202(4):271-4.
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Garfield LD, Scherrer JF, Hauptman PJ, Freedland KE, Chrusciel T, Balasubramanian S, Carney RM, Newcomer JW, Owen R, Bucholz KK, Lustman PJ. Association of anxiety disorders and depression with incident heart failure. Psychosom Med. 2014 Feb; 76(2):128-36.
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Makhoul I. Can happiness improve cancer survival? J Ark Med Soc. 2013 Dec; 110(7):126-7.
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Rohan ML, Yamamoto RT, Ravichandran CT, Cayetano KR, Morales OG, Olson DP, Vitaliano G, Paul SM, Cohen BM. Rapid mood-elevating effects of low field magnetic stimulation in depression. Biol Psychiatry. 2014 Aug 01; 76(3):186-93.
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Bryant K, Wicks MN, Willis N. Recruitment of older African American males for depression research: lessons learned. Arch Psychiatr Nurs. 2014 Feb; 28(1):17-20.
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Zubenko GS, Hughes HB, Hitchens TK, Cohen BM. Alterations of brain anatomy in mouse model of MDD created by replacement of homologous mouse DNA sequence with an illness-associated 6-base human CREB1 promoter sequence. Am J Med Genet B Neuropsychiatr Genet. 2014 Jan; 165B(1):1-8.
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Mundt JC, Greist JH, Jefferson JW, Federico M, Mann JJ, Posner K. Prediction of suicidal behavior in clinical research by lifetime suicidal ideation and behavior ascertained by the electronic Columbia-Suicide Severity Rating Scale. J Clin Psychiatry. 2013 Sep; 74(9):887-93.
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Johnson KC, Brennan PA, Stowe ZN, Leibenluft E, Newport DJ. Physiological regulation in infants of women with a mood disorder: examining associations with maternal symptoms and stress. J Child Psychol Psychiatry. 2014; 55(2):191-8.
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