 Alkaloids
"Alkaloids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)
| Descriptor ID |
D000470
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| MeSH Number(s) |
D03.132
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Alkaloids".
Below are MeSH descriptors whose meaning is more specific than "Alkaloids".
This graph shows the total number of publications written about "Alkaloids" by people in UAMS Profiles by year, and whether "Alkaloids" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 2 | 0 | 2 | | 2021 | 2 | 0 | 2 | | 2020 | 1 | 2 | 3 | | 2019 | 0 | 2 | 2 | | 2018 | 1 | 0 | 1 | | 2017 | 2 | 0 | 2 | | 2015 | 0 | 1 | 1 | | 2014 | 0 | 2 | 2 | | 2013 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2005 | 2 | 0 | 2 | | 2004 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 1998 | 2 | 0 | 2 | | 1996 | 0 | 1 | 1 | | 1993 | 0 | 1 | 1 |
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Below are the most recent publications written about "Alkaloids" by people in Profiles over the past ten years.
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Fitzgerald LR, Gannon BM, Walther D, Landavazo A, Hiranita T, Blough BE, Baumann MH, Fantegrossi WE. Structure-activity relationships for locomotor stimulant effects and monoamine transporter interactions of substituted amphetamines and cathinones. Neuropharmacology. 2024 Mar 01; 245:109827.
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Zhang B, Li B, Xie Y, Chang S, Xu Z, Hu H, Chen G, Zhang T, He J, Wu X, Zhu H, Lai W, Song D, Lu Y, Jia X, Zhu W, Shi J. A novel alkaloid compound, DCZ0358, exerts significant antitumor activity in bortezomib-resistant multiple myeloma cells through inhibition of JAK2/STAT3 pathway. Acta Biochim Biophys Sin (Shanghai). 2023 Feb 25; 55(2):215-224.
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Panda S, Jozwiak A, Sonawane PD, Szymanski J, Kazachkova Y, Vainer A, Vasuki Kilambi H, Almekias-Siegl E, Dikaya V, Bocobza S, Shohat H, Meir S, Wizler G, Giri AP, Schuurink R, Weiss D, Yasuor H, Kamble A, Aharoni A. Steroidal alkaloids defence metabolism and plant growth are modulated by the joint action of gibberellin and jasmonate signalling. New Phytol. 2022 02; 233(3):1220-1237.
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Bowroju SK, Penthala NR, Lakkaniga NR, Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ, Crooks PA. Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease. Bioorg Med Chem. 2021 09 01; 45:116311.
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Porras G, Chassagne F, Lyles JT, Marquez L, Dettweiler M, Salam AM, Samarakoon T, Shabih S, Farrokhi DR, Quave CL. Ethnobotany and the Role of Plant Natural Products in Antibiotic Drug Discovery. Chem Rev. 2021 03 24; 121(6):3495-3560.
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McClenahan SJ, Gunnell MG, Owens SM, Fantegrossi WE. Active vaccination reduces reinforcing effects of MDPV in male Sprague-Dawley rats trained to self-administer cocaine. Psychopharmacology (Berl). 2020 Sep; 237(9):2613-2620.
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Deng T, Wei Z, Gael A, Deng X, Liu Y, Lai J, Hang L, Yan Q, Fu Q, Li Z. Higenamine Improves Cardiac and Renal Fibrosis in Rats With Cardiorenal Syndrome via ASK1 Signaling Pathway. J Cardiovasc Pharmacol. 2020 06; 75(6):535-544.
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Xu X, Chen Y, Fu Q, Ni D, Zhang J, Li X, Lu S. The chemical diversity and structure-based discovery of allosteric modulators for the PIF-pocket of protein kinase PDK1. J Enzyme Inhib Med Chem. 2019 Dec; 34(1):361-374.
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Hyatt WS, Berquist MD, Chitre NM, Russell LN, Rice KC, Murnane KS, Fantegrossi WE. Repeated administration of synthetic cathinone 3,4-methylenedioxypyrovalerone persistently increases impulsive choice in rats. Behav Pharmacol. 2019 10; 30(7):555-565.
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Gannon BM, Baumann MH, Walther D, Jimenez-Morigosa C, Sulima A, Rice KC, Collins GT. The abuse-related effects of pyrrolidine-containing cathinones are related to their potency and selectivity to inhibit the dopamine transporter. Neuropsychopharmacology. 2018 11; 43(12):2399-2407.
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Hamed ANE, Schmitz R, Bergermann A, Totzke F, Kubbutat M, M?ller WEG, Youssef DTA, Bishr MM, Kamel MS, Edrada-Ebel R, W?tjen W, Proksch P. Bioactive pyrrole alkaloids isolated from the Red Sea: marine sponge Stylissa carteri. Z Naturforsch C J Biosci. 2018 Apr 25; 73(5-6):199-210.
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Frasinyuk MS, Zhang W, Wyrebek P, Yu T, Xu X, Sviripa VM, Bondarenko SP, Xie Y, Ngo HX, Morris AJ, Mohler JL, Fiandalo MV, Watt DS, Liu C. Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4). Org Biomol Chem. 2017 Sep 20; 15(36):7623-7629.
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Shady NH, El-Hossary EM, Fouad MA, Gulder TAM, Kamel MS, Abdelmohsen UR. Bioactive Natural Products of Marine Sponges from the Genus Hyrtios. Molecules. 2017 May 11; 22(5).
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