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Andrew Morris

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPharmacology and Toxicology, College of Medicine
Address110C BIOMED
4301 W. Markham
Mail Slot # 611
Little Rock AR 72205
ORCID ORCID Icon0000-0003-1910-4865 Additional info
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    Collapse Research 
    Collapse research activities and funding
    IK6BX006469     (MORRIS, ANDREW J)Oct 1, 2023 - Sep 30, 2028
    NIH
    BLRD Research Career Scientist Award Application
    Role: Principal Investigator
    1R37CA282349     (FIL, AMANDA J)Aug 10, 2023 - Jul 31, 2028
    NIH/Nat. Cancer Institute
    Ryanodine Receptors as Therapeutic Targets to Prevent Doxorubicin-Induced Lymphatic Dysfunction
    Role: Principal Investigator
    I01BX005637     (MORRIS, ANDREW J)Apr 1, 2021 - Mar 31, 2025
    NIH
    Lysophosphatidic Acid and Cardiovascular Disease Risk
    Role: Principal Investigator
    I01BX004671     (MORRIS, ANDREW J)Apr 1, 2020 - Jun 30, 2025
    NIH
    Serum Amyloid as a Critical mediator between inflammation and thrombosis
    Role: Principal Investigator
    IS1BX004791     (MORRIS, ANDREW J)Jan 1, 2019 - Sep 30, 2019
    NIH
    ShEEP Request For Gas Chromatograph Mass Spectrometer
    Role: Principal Investigator
    S10OD021753     (MORRIS, ANDREW J)Mar 15, 2017 - Mar 14, 2018
    NIH
    Triple Quadrupole Mass Spectrometer System
    Role: Principal Investigator
    R01HL120507     (SMYTH, SUSAN S.)Apr 1, 2015 - Mar 31, 2021
    NIH
    Lipid phosphate phosphatase 3 as a novel atherosclerosis suppressor
    Role: Co-Principal Investigator
    IS1BX003153     (MORRIS, ANDREW J)Apr 1, 2015 - Sep 30, 2015
    NIH
    Acquisition of an HPLC Electrospray/chemical ionization triple quadrupole linear ion trap mass spectrometer system.
    Role: Principal Investigator
    I01CX001550     (MORRIS, ANDREW J)Jan 1, 2013 - Dec 31, 2020
    NIH
    Lysophosphatidic acid and cardiovascular disease risk
    Role: Principal Investigator
    I01BX001984     (MORRIS, ANDREW J)Jan 1, 2013 - Dec 31, 2016
    NIH
    Association of a common variant of the PPAP2B gene with cardiovascular disease.
    Role: Principal Investigator
    S10RR026884     (MORRIS, ANDREW J)May 1, 2011 - Apr 30, 2012
    NIH
    Advion Triversa Nanomate/ABSciex Nanospray III Ion Source for Targeted Lipidomics
    Role: Principal Investigator
    S10RR024598     (MORRIS, ANDREW J)Mar 1, 2008 - Feb 28, 2009
    NIH
    Thermo/Finnigan TSQ AM Triple Stage Quadrupole Mass Spectrometer
    Role: Principal Investigator
    R13HL082350     (MORRIS, ANDREW J)Aug 1, 2005 - Jul 31, 2006
    NIH
    FASEB SUMMER RESEARCH CONFERENCE: BIOACTIVE LYSOLIPIDS
    Role: Principal Investigator
    R13AI062394     (MORRIS, ANDREW J)Jul 15, 2004 - Jun 30, 2005
    NIH
    FASEB Summer Conference on Phospholipases
    Role: Principal Investigator
    R01CA096496     (MORRIS, ANDREW J)Feb 1, 2002 - Jan 31, 2008
    NIH
    Lysophospholipid Mediators in Ovarian Cancer
    Role: Principal Investigator
    S10RR012856     (MORRIS, ANDREW J)Jan 21, 1999 - Jan 20, 2000
    NIH
    BIACORE 2000 SURFACE PLASMON RESONANCE BIOSENSOR
    Role: Principal Investigator
    R55GM054641     (MORRIS, ANDREW J)Sep 15, 1996 - Sep 14, 1999
    NIH
    REGULATION OF PHOSPHOLIPASE D
    Role: Principal Investigator
    R01GM050388     (MORRIS, ANDREW J)Aug 1, 1994 - Jun 30, 2014
    NIH
    Role of Lipid Phosphatases in Cholesterol and Triglyceride Synthesis
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Morris AJ, Moolenaar WH. How does lipid phosphatase 1 (LPP1) regulate antitumor CD8+ T cell activity? Immunity. 2025 Aug 12; 58(8):1871-1872. PMID: 40803308.
      View in: PubMed
    2. Sims CR, Sehgal N, Turner D, Havens LA, Morris AJ, Shankar K, Pearson KJ, Everson TM, Andres A. Individual and mixtures of PFAS during pregnancy are associated with maternal cardiometabolic outcomes during pregnancy. Environ Health. 2025 Apr 30; 24(1):26. PMID: 40307774.
      View in: PubMed
    3. Park K, Ju S, Choi H, Gao P, Bang G, Choi JH, Jang J, Morris AJ, Kang BH, Hsu VW, Park SY. PITP? promotes COPI vesicle fission through lipid transfer and membrane contact formation. J Cell Biol. 2025 May 05; 224(5). PMID: 40214667.
      View in: PubMed
    4. Hameed A, Ferruzzi MG, Kay CD, Williams DK, Rahbar E, Morris AJ. Comparison of the capillary and venous blood plasma lipidomes: validation of self-collected blood for plasma lipidomics. J Lipid Res. 2025 Mar; 66(3):100755. PMID: 39952568.
      View in: PubMed
    5. Wang S, Jin Z, Wu B, Morris AJ, Deng P. Role of dietary and nutritional interventions in ceramide-associated diseases. J Lipid Res. 2025 Jan; 66(1):100726. PMID: 39667580.
      View in: PubMed
    6. Daneman N, Rishu A, Pinto R, Rogers BA, Shehabi Y, Parke R, Cook D, Arabi Y, Muscedere J, Reynolds S, Hall R, Dwivedi DB, McArthur C, McGuinness S, Yahav D, Coburn B, Geagea A, Das P, Shin P, Detsky M, Morris A, Fralick M, Powis JE, Kandel C, Sligl W, Bagshaw SM, Singhal N, Belley-Cote E, Whitlock R, Khwaja K, Morpeth S, Kazemi A, Williams A, MacFadden DR, McIntyre L, Tsang J, Lamontagne F, Carignan A, Marshall J, Friedrich JO, Cirone R, Downing M, Graham C, Davis J, Duan E, Neary J, Evans G, Alraddadi B, Al Johani S, Martin C, Elsayed S, Ball I, Lauzier F, Turgeon A, Stelfox HT, Conly J, McDonald EG, Lee TC, Sullivan R, Grant J, Kagan I, Young P, Lawrence C, O'Callaghan K, Eustace M, Choong K, Aslanian P, Buehner U, Havey T, Binnie A, Prazak J, Reeve B, Litton E, Lother S, Kumar A, Zarychanski R, Hoffman T, Paterson D, Daley P, Commons RJ, Charbonney E, Naud JF, Roberts S, Tiruvoipati R, Gupta S, Wood G, Shum O, Miyakis S, Dodek P, Kwok C, Fowler RA. Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections. N Engl J Med. 2025 Mar 13; 392(11):1065-1078. PMID: 39565030.
      View in: PubMed
    7. Park K, Ju S, Choi H, Gao P, Bang G, Choi JH, Jang J, Morris AJ, Kang BH, Hsu VW, Park SY. PITP? promotes COPI vesicle fission through lipid transfer and membrane contact formation. bioRxiv. 2024 Jul 25. PMID: 38853868.
      View in: PubMed
    8. Prabakaran AD, McFarland K, Miz K, Durumutla HB, Piczer K, El Abdellaoui Soussi F, Latimer H, Werbrich C, Chung HJ, Blair NS, Millay DP, Morris AJ, Prideaux B, Finck BN, Quattrocelli M. Intermittent glucocorticoid treatment improves muscle metabolism via the PGC1a/Lipin1 axis in an aging-related sarcopenia model. J Clin Invest. 2024 May 03; 134(11). PMID: 38702076.
      View in: PubMed
    9. Evans ML, Bergsma J, Merkys A, Andersen CW, Andersson OB, Beltr?n D, Blokhin E, Boland TM, Casta?eda Balderas R, Choudhary K, D?az D?az A, Dom?nguez Garc?a R, Eckert H, Eimre K, Fuentes Montero ME, Krajewski AM, Mortensen JJ, N?poles Duarte JM, Pietryga J, Qi J, Trejo Carrillo FJ, Vaitkus A, Yu J, Zettel A, de Castro PB, Carlsson J, Cerqueira TFT, Divilov S, Hajiyani H, Hanke F, Jose K, Oses C, Riebesell J, Schmidt J, Winston D, Xie C, Yang X, Bonella S, Botti S, Curtarolo S, Draxl C, Fuentes Cobas LE, Hospital A, Liu ZK, Marques MAL, Marzari N, Morris AJ, Ong SP, Orozco M, Persson KA, Thygesen KS, Wolverton C, Scheidgen M, Toher C, Conduit GJ, Pizzi G, Gra?ulis S, Rignanese GM, Armiento R. Developments and applications of the OPTIMADE API for materials discovery, design, and data exchange. Digit Discov. 2024 Aug 07; 3(8):1509-1533. PMID: 39118978.
      View in: PubMed
    10. Li J, Yang L, Song J, Yan B, Morris AJ, Moseley H, Flight R, Wang C, Liu J, Weiss HL, Morris EF, Abdelhamid I, Gerl MJ, Melander O, Smyth S, Evers BM. Neurotensin accelerates atherosclerosis and increases circulating levels of short-chain and saturated triglycerides. Atherosclerosis. 2024 05; 392:117479. PMID: 38423808.
      View in: PubMed
    11. Britt RK, Carmack HJ, Morris A, Chakraborty AR, Franco CL. Does Organizational Messaging Make a Difference? Investigating Themes and Language Style in Twitter Discourse and Engagement by Mental Health Organizations. J Health Commun. 2024 01 02; 29(1):1-8. PMID: 37961904.
      View in: PubMed
    12. Lambarth A, Katsoulis M, Ju C, Warwick A, Takhar R, Dale C, Prieto-Merino D, Morris A, Sen D, Wei L, Sofat R. Prevalence of chronic pain or analgesic use in children and young people and its long-term impact on substance misuse, mental illness, and prescription opioid use: a retrospective longitudinal cohort study. Lancet Reg Health Eur. 2023 Dec; 35:100763. PMID: 38115960.
      View in: PubMed
    13. Morris AJ, Rueckeis CA. Sap and Sun: A Case of Phytophotodermatitis. Wilderness Environ Med. 2023 12; 34(4):532-535. PMID: 37802751.
      View in: PubMed
    14. Arun P, Wilder DM, Morris AJ, Sabbadini R, Long JB. Cerebrospinal Fluid Levels of Lysophosphatidic Acids Can Provide Suitable Biomarkers of Blast-Induced Traumatic Brain Injury. J Neurotrauma. 2023 Nov; 40(21-22):2289-2296. PMID: 37279302.
      View in: PubMed
    15. Hoffmann C, Morris A, Timmins L, Cui X, Sachdeva R, Walsh S, Wulkan M, Brewster L. Sleeve gastrectomy may improve arterial health in obese adolescents. Nutr Metab Cardiovasc Dis. 2023 10; 33(10):2053-2054. PMID: 37544870.
      View in: PubMed
    16. Tang X, Morris AJ, Deken MA, Brindley DN. Autotaxin Inhibition with IOA-289 Decreases Breast Tumor Growth in Mice Whereas Knockout of Autotaxin in Adipocytes Does Not. Cancers (Basel). 2023 May 26; 15(11). PMID: 37296899.
      View in: PubMed
    17. Kipp ZA, Martinez GJ, Bates EA, Maharramov AB, Flight RM, Moseley HNB, Morris AJ, Stec DE, Hinds TD. Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content. Metabolites. 2023 Feb 01; 13(2). PMID: 36837834.
      View in: PubMed
    18. Bates EA, Kipp ZA, Martinez GJ, Badmus OO, Soundarapandian MM, Foster D, Xu M, Creeden JF, Greer JR, Morris AJ, Stec DE, Hinds TD. Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease. Biomolecules. 2023 01 29; 13(2). PMID: 36830621.
      View in: PubMed
    19. Morgan S, Mottaleb MA, Kraemer MP, Moser DK, Worley J, Morris AJ, Petriello MC. Effect of lifestyle-based lipid lowering interventions on the relationship between circulating levels of per-and polyfluoroalkyl substances and serum cholesterol. Environ Toxicol Pharmacol. 2023 Mar; 98:104062. PMID: 36621559.
      View in: PubMed
    20. Jefferson E, Cole C, Mumtaz S, Cox S, Giles TC, Adejumo S, Urwin E, Lea D, Macdonald C, Best J, Masood E, Milligan G, Johnston J, Horban S, Birced I, Hall C, Jackson AS, Collins C, Rising S, Dodsley C, Hampton J, Hadfield A, Santos R, Tarr S, Panagi V, Lavagna J, Jackson T, Chuter A, Beggs J, Martinez-Queipo M, Ward H, von Ziegenweidt J, Burns F, Martin J, Sebire N, Morris C, Bradley D, Baxter R, Ahonen-Bishopp A, Smith P, Shoemark A, Valdes AM, Ollivere B, Manisty C, Eyre D, Gallant S, Joy G, McAuley A, Connell D, Northstone K, Jeffery K, Di Angelantonio E, McMahon A, Walker M, Semple MG, Sims JM, Lawrence E, Davies B, Baillie JK, Tang M, Leeming G, Power L, Breeze T, Murray D, Orton C, Pierce I, Hall I, Ladhani S, Gillson N, Whitaker M, Shallcross L, Seymour D, Varma S, Reilly G, Morris A, Hopkins S, Sheikh A, Quinlan P. A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study. J Med Internet Res. 2022 12 27; 24(12):e40035. PMID: 36322788.
      View in: PubMed
    21. Tenlep SYN, Weaver M, Chen J, Vsevolozhskaya O, Morris AJ, Rashid CS. Tris(1,3-dichloro-2-propyl) phosphate is a metabolism-disrupting chemical in male mice. Toxicol Lett. 2023 Feb 01; 374:31-39. PMID: 36493961.
      View in: PubMed
    22. Tripathi H, Shindo K, Donahue RR, Gao E, Kuppa A, ElKammar M, Morris AJ, Smyth SS, Abdel-Latif A. Myeloid-Specific Deletion of Lipid Plpp3 (Phosphate Phosphatase 3) Increases Cardiac Inflammation After Myocardial Infarction. Arterioscler Thromb Vasc Biol. 2023 02; 43(2):379-381. PMID: 36453277.
      View in: PubMed
    23. Sharma DS, Wadhwa S, Gulati M, Kumar B, Chitranshi N, Gupta VK, Alrouji M, Alhajlah S, AlOmeir O, Vishwas S, Khursheed R, Saini S, Kumar A, Parveen SR, Gupta G, Zacconi F, Chellappan DK, Morris A, Loebenberg R, Dua K, Singh SK. Chitosan modified 5-fluorouracil nanostructured lipid carriers for treatment of diabetic retinopathy in rats: A new dimension to an anticancer drug. Int J Biol Macromol. 2023 Jan 01; 224:810-830. PMID: 36302483.
      View in: PubMed
    24. Kaur J, Gulati M, Zacconi F, Dureja H, Loebenberg R, Ansari MS, AlOmeir O, Alam A, Chellappan DK, Gupta G, Jha NK, Pinto TJA, Morris A, Choonara YE, Adams J, Dua K, Singh SK. Biomedical Applications of polymeric micelles in the treatment of diabetes mellitus: Current success and future approaches. Expert Opin Drug Deliv. 2022 07; 19(7):771-793. PMID: 35695697.
      View in: PubMed
    25. Yverneau M, Leroux S, Imbard A, Gleich F, Arion A, Moreau C, Nassogne MC, Szymanowski M, Tardieu M, Touati G, Bueno M, Chapman KA, Chien YH, Huemer M, Je?ina P, Janssen MCH, K?lker S, Ko?ich V, Lavigne C, Lund AM, Mochel F, Morris A, Pons MR, Porras-Hurtado GL, Benoist JF, Damaj L, Schiff M. Influence of early identification and therapy on long-term outcomes in early-onset MTHFR deficiency. J Inherit Metab Dis. 2022 07; 45(4):848-861. PMID: 35460084.
      View in: PubMed
    26. Kaur J, Gulati M, Kapoor B, Jha NK, Gupta PK, Gupta G, Chellappan DK, Devkota HP, Prasher P, Ansari MS, Aba Alkhayl FF, Arshad MF, Morris A, Choonara YE, Adams J, Dua K, Singh SK. Advances in designing of polymeric micelles for biomedical application in brain related diseases. Chem Biol Interact. 2022 Jul 01; 361:109960. PMID: 35533733.
      View in: PubMed
    27. Goff DA, Gauthier TP, Langford BJ, Prusakov P, Ubaka Chukwuemka M, Nwomeh BC, Yunis KA, Saad T, van den Bergh D, Villegas MV, Martinez N, Morris A, Ashiru-Oredope D, Howard P, Sanchez PJ. Global resilience and new strategies needed for antimicrobial stewardship during the COVID-19 pandemic and beyond. J Am Coll Clin Pharm. 2022 Jul; 5(7):707-715. PMID: 35572210.
      View in: PubMed
    28. Van Hoose PM, Yang L, Kraemer M, Ubele M, Morris AJ, Smyth SS. Lipid phosphate phosphatase 3 in smooth muscle cells regulates angiotensin II-induced abdominal aortic aneurysm formation. Sci Rep. 2022 04 05; 12(1):5664. PMID: 35383201.
      View in: PubMed
    29. Araujo N, Sledziona J, Noothi SK, Burikhanov R, Hebbar N, Ganguly S, Shrestha-Bhattarai T, Zhu B, Katz WS, Zhang Y, Taylor BS, Liu J, Chen L, Weiss HL, He D, Wang C, Morris AJ, Cassis LA, Nikolova-Karakashian M, Nagareddy PR, Melander O, Evers BM, Kern PA, Rangnekar VM. Tumor Suppressor Par-4 Regulates Complement Factor C3 and Obesity. Front Oncol. 2022; 12:860446. PMID: 35425699.
      View in: PubMed
    30. Henry N, Frank J, McLouth C, Trout AL, Morris A, Chen J, Stowe AM, Fraser JF, Pennypacker K. Short Chain Fatty Acids Taken at Time of Thrombectomy in Acute Ischemic Stroke Patients Are Independent of Stroke Severity But Associated With Inflammatory Markers and Worse Symptoms at Discharge. Front Immunol. 2021; 12:797302. PMID: 35126360.
      View in: PubMed
    31. Hinds TD, Kipp ZA, Xu M, Yiannikouris FB, Morris AJ, Stec DF, Wahli W, Stec DE. Adipose-Specific PPARa Knockout Mice Have Increased Lipogenesis by PASK-SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue. Cells. 2021 12 21; 11(1). PMID: 35011564.
      View in: PubMed
    32. Sui Y, Meng Z, Chen J, Liu J, Hernandez R, Gonzales MB, Gwag T, Morris AJ, Zhou C. Effects of Dicyclohexyl Phthalate Exposure on PXR Activation and Lipid Homeostasis in Mice. Environ Health Perspect. 2021 12; 129(12):127001. PMID: 34851150.
      View in: PubMed
    33. Matas-Rico E, Frijlink E, van der Haar ?vila I, Menegakis A, van Zon M, Morris AJ, Koster J, Salgado-Polo F, de Kivit S, Lan?a T, Mazzocca A, Johnson Z, Haanen J, Schumacher TN, Perrakis A, Verbrugge I, van den Berg JH, Borst J, Moolenaar WH. Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T?cells. Cell Rep. 2021 11 16; 37(7):110013. PMID: 34788605.
      View in: PubMed
    34. Petriello MC, Mottaleb MA, Serio TC, Balyan B, Cave MC, Pavuk M, Birnbaum LS, Morris AJ. Serum concentrations of legacy and emerging per- and polyfluoroalkyl substances in the Anniston Community Health Surveys (ACHS I and ACHS II). Environ Int. 2022 01; 158:106907. PMID: 34763231.
      View in: PubMed
    35. Andersen CW, Armiento R, Blokhin E, Conduit GJ, Dwaraknath S, Evans ML, Fekete ?, Gopakumar A, Gra?ulis S, Merkys A, Mohamed F, Oses C, Pizzi G, Rignanese GM, Scheidgen M, Talirz L, Toher C, Winston D, Aversa R, Choudhary K, Colinet P, Curtarolo S, Di Stefano D, Draxl C, Er S, Esters M, Fornari M, Giantomassi M, Govoni M, Hautier G, Hegde V, Horton MK, Huck P, Huhs G, Hummelsh?j J, Kariryaa A, Kozinsky B, Kumbhar S, Liu M, Marzari N, Morris AJ, Mostofi AA, Persson KA, Petretto G, Purcell T, Ricci F, Rose F, Scheffler M, Speckhard D, Uhrin M, Vaitkus A, Villars P, Waroquiers D, Wolverton C, Wu M, Yang X. OPTIMADE, an API for exchanging materials data. Sci Data. 2021 08 12; 8(1):217. PMID: 34385453.
      View in: PubMed
    36. Mottaleb MA, Ding QX, Pennell KG, Haynes EN, Morris AJ. Direct injection analysis of per and polyfluoroalkyl substances in surface and drinking water by sample filtration and liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2021 Sep 13; 1653:462426. PMID: 34352431.
      View in: PubMed
    37. Supinski GS, Schroder EA, Wang L, Morris AJ, Callahan LAP. Mitoquinone mesylate (MitoQ) prevents sepsis-induced diaphragm dysfunction. J Appl Physiol (1985). 2021 08 01; 131(2):778-787. PMID: 34197233.
      View in: PubMed
    38. Sydes MR, Barbachano Y, Bowman L, Denwood T, Farmer A, Garfield-Birkbeck S, Gibson M, Gulliford MC, Harrison DA, Hewitt C, Logue J, Navaie W, Norrie J, O'Kane M, Quint JK, Rycroft-Malone J, Sheffield J, Smeeth L, Sullivan F, Tizzard J, Walker P, Wilding J, Williamson PR, Landray M, Morris A, Walker RR, Williams HC, Valentine J. Realising the full potential of data-enabled trials in the UK: a call for action. BMJ Open. 2021 06 16; 11(6):e043906. PMID: 34135032.
      View in: PubMed
    39. Deng P, Valentino T, Flythe MD, Moseley HNB, Leachman JR, Morris AJ, Hennig B. Untargeted Stable Isotope Probing of the Gut Microbiota Metabolome Using 13C-Labeled Dietary Fibers. J Proteome Res. 2021 05 07; 20(5):2904-2913. PMID: 33830777.
      View in: PubMed
    40. Finlin BS, Memetimin H, Zhu B, Confides AL, Vekaria HJ, El Khouli RH, Johnson ZR, Westgate PM, Chen J, Morris AJ, Sullivan PG, Dupont-Versteegden EE, Kern PA. Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism. JCI Insight. 2021 03 22; 6(6). PMID: 33571166.
      View in: PubMed
    41. Zhu N, Zhang C, Prakash A, Hou Z, Liu W, She W, Morris A, Sik Kim K. Therapeutic development of group B Streptococcus meningitis by targeting a host cell signaling network involving EGFR. EMBO Mol Med. 2021 03 05; 13(3):e12651. PMID: 33474818.
      View in: PubMed
    42. Eke J, Banks L, Mottaleb MA, Morris AJ, Tsyusko OV, Escobar IC. Dual-Functional Phosphorene Nanocomposite Membranes for the Treatment of Perfluorinated Water: An Investigation of Perfluorooctanoic Acid Removal via Filtration Combined with Ultraviolet Irradiation or Oxygenation. Membranes (Basel). 2020 Dec 25; 11(1). PMID: 33375603.
      View in: PubMed
    43. Arun P, Rossetti F, DeMar JC, Wang Y, Batuure AB, Wilder DM, Gist ID, Morris AJ, Sabbadini RA, Long JB. Antibodies Against Lysophosphatidic Acid Protect Against Blast-Induced Ocular Injuries. Front Neurol. 2020; 11:611816. PMID: 33384658.
      View in: PubMed
    44. Ruckert A, Fafard P, Hindmarch S, Morris A, Packer C, Patrick D, Weese S, Wilson K, Wong A, Labont? R. Governing antimicrobial resistance: a narrative review of global governance mechanisms. J Public Health Policy. 2020 Dec; 41(4):515-528. PMID: 32908184.
      View in: PubMed
    45. Xiang B, Zhang G, Zhang Y, Wu C, Joshi S, Morris AJ, Ware J, Smyth SS, Whiteheart SW, Li Z. Calcium Ion Chelation Preserves Platelet Function During Cold Storage. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):234-249. PMID: 33176450.
      View in: PubMed
    46. Thalman C, Horta G, Qiao L, Endle H, Tegeder I, Cheng H, Laube G, Sigurdsson T, Hauser MJ, Tenzer S, Distler U, Aoki J, Morris AJ, Geisslinger G, R?per J, Kirischuk S, Luhmann HJ, Radyushkin K, Nitsch R, Vogt J. Correction: Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders. Mol Psychiatry. 2020 Nov; 25(11):3108. PMID: 30602735.
      View in: PubMed
    47. Deng P, Wang C, Wahlang B, Sexton T, Morris AJ, Hennig B. Co-exposure to PCB126 and PFOS increases biomarkers associated with cardiovascular disease risk and liver injury in mice. Toxicol Appl Pharmacol. 2020 12 15; 409:115301. PMID: 33096110.
      View in: PubMed
    48. Tripathi H, Al-Darraji A, Abo-Aly M, Peng H, Shokri E, Chelvarajan L, R Donahue R, Levitan BM, Gao E, Hernandez G, Morris AJ, Smyth SS, Abdel-Latif A. Autotaxin inhibition reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction. J Mol Cell Cardiol. 2020 12; 149:95-114. PMID: 33017574.
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    49. Nind T, Sutherland J, McAllister G, Hardy D, Hume A, MacLeod R, Caldwell J, Krueger S, Tramma L, Teviotdale R, Abdelatif M, Gillen K, Ward J, Scobbie D, Baillie I, Brooks A, Prodan B, Kerr W, Sloan-Murphy D, Herrera JFR, McManus D, Morris C, Sinclair C, Baxter R, Parsons M, Morris A, Jefferson E. An extensible big data software architecture managing a research resource of real-world clinical radiology data linked to other health data from the whole Scottish population. Gigascience. 2020 09 29; 9(10). PMID: 32990744.
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    50. Guo Y, Ye Q, Deng P, Cao Y, He D, Zhou Z, Wang C, Zaytseva YY, Schwartz CE, Lee EY, Evers BM, Morris AJ, Liu S, She QB. Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression. Nat Commun. 2020 06 26; 11(1):3243. PMID: 32591507.
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    51. Mottaleb MA, Petriello MC, Morris AJ. High-Throughput UHPLC-MS/MS Measurement of Per- and Poly-Fluorinated Alkyl Substances in Human Serum. J Anal Toxicol. 2020 May 18; 44(4):339-347. PMID: 31776573.
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    52. Smyth SS, Kraemer M, Yang L, Van Hoose P, Morris AJ. Roles for lysophosphatidic acid signaling in vascular development and disease. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 08; 1865(8):158734. PMID: 32376340.
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    53. Finlin BS, Memetimin H, Zhu B, Confides AL, Vekaria HJ, El Khouli RH, Johnson ZR, Westgate PM, Chen J, Morris AJ, Sullivan PG, Dupont-Versteegden EE, Kern PA. The ?3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans. J Clin Invest. 2020 05 01; 130(5):2319-2331. PMID: 31961829.
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    54. Hoffman JB, Petriello MC, Morris AJ, Mottaleb MA, Sui Y, Zhou C, Deng P, Wang C, Hennig B. Prebiotic inulin consumption reduces dioxin-like PCB 126-mediated hepatotoxicity and gut dysbiosis in hyperlipidemic Ldlr deficient mice. Environ Pollut. 2020 Jun; 261:114183. PMID: 32105967.
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    55. Onono FO, Morris AJ. Phospholipase D and Choline Metabolism. Handb Exp Pharmacol. 2020; 259:205-218. PMID: 32086667.
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    56. Griffith KJ, Seymour ID, Hope MA, Butala MM, Lamontagne LK, Preefer MB, Ko?er CP, Henkelman G, Morris AJ, Cliffe MJ, Dutton SE, Grey CP. Ionic and Electronic Conduction in TiNb2O7. J Am Chem Soc. 2019 Oct 23; 141(42):16706-16725. PMID: 31487157.
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    57. Deng P, Hoffman JB, Petriello MC, Wang CY, Li XS, Kraemer MP, Morris AJ, Hennig B. Dietary inulin decreases circulating ceramides by suppressing neutral sphingomyelinase expression and activity in mice. J Lipid Res. 2020 01; 61(1):45-53. PMID: 31604806.
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    58. Deng P, Li X, Petriello MC, Wang C, Morris AJ, Hennig B. Application of metabolomics to characterize environmental pollutant toxicity and disease risks. Rev Environ Health. 2019 Sep 25; 34(3):251-259. PMID: 31408434.
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    59. Mueller PA, Yang L, Ubele M, Mao G, Brandon J, Vandra J, Nichols TC, Escalante-Alcalde D, Morris AJ, Smyth SS. Coronary Artery Disease Risk-Associated Plpp3 Gene and Its Product Lipid Phosphate Phosphatase 3 Regulate Experimental Atherosclerosis. Arterioscler Thromb Vasc Biol. 2019 11; 39(11):2261-2272. PMID: 31533471.
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    60. Chen S, Henderson A, Petriello MC, Romano KA, Gearing M, Miao J, Schell M, Sandoval-Espinola WJ, Tao J, Sha B, Graham M, Crooke R, Kleinridders A, Balskus EP, Rey FE, Morris AJ, Biddinger SB. Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction. Cell Metab. 2019 12 03; 30(6):1141-1151.e5. PMID: 31543404.
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    61. Kraemer MP, Mao G, Hammill C, Yan B, Li Y, Onono F, Smyth SS, Morris AJ. Effects of diet and hyperlipidemia on levels and distribution of circulating lysophosphatidic acid. J Lipid Res. 2019 11; 60(11):1818-1828. PMID: 31484695.
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    62. Mao G, Smyth SS, Morris AJ. Regulation of PLPP3 gene expression by NF-?B family transcription factors. J Biol Chem. 2019 09 20; 294(38):14009-14019. PMID: 31362988.
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    63. Park SY, Yang JS, Li Z, Deng P, Zhu X, Young D, Ericsson M, Andringa RLH, Minnaard AJ, Zhu C, Sun F, Moody DB, Morris AJ, Fan J, Hsu VW. The late stage of COPI vesicle fission requires shorter forms of phosphatidic acid and diacylglycerol. Nat Commun. 2019 07 30; 10(1):3409. PMID: 31363100.
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    64. Jackson EN, Thatcher SE, Larian N, English V, Soman S, Morris AJ, Weng J, Stromberg A, Swanson HI, Pearson K, Cassis LA. Effects of Aryl Hydrocarbon Receptor Deficiency on PCB-77-Induced Impairment of Glucose Homeostasis during Weight Loss in Male and Female Obese Mice. Environ Health Perspect. 2019 07; 127(7):77004. PMID: 31306034.
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    65. Morris AJ. Phospholipases D: making sense of redundancy and duplication. Biosci Rep. 2019 Jun 28; 39(6). PMID: 31189747.
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    66. AlSiraj Y, Chen X, Thatcher SE, Temel RE, Cai L, Blalock E, Katz W, Ali HM, Petriello M, Deng P, Morris AJ, Wang X, Lusis AJ, Arnold AP, Reue K, Thompson K, Tso P, Cassis LA. XX sex chromosome complement promotes atherosclerosis in mice. Nat Commun. 2019 06 14; 10(1):2631. PMID: 31201301.
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    67. Zhu Z, Chen J, Wang G, Elsherbini A, Zhong L, Jiang X, Qin H, Tripathi P, Zhi W, Spassieva SD, Morris AJ, Bieberich E. Ceramide regulates interaction of Hsd17b4 with Pex5 and function of peroxisomes. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 10; 1864(10):1514-1524. PMID: 31176039.
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    68. Larian N, Ensor M, Thatcher SE, English V, Morris AJ, Stromberg A, Cassis LA. Pseudomonas aeruginosa-derived pyocyanin reduces adipocyte differentiation, body weight, and fat mass as mechanisms contributing to septic cachexia. Food Chem Toxicol. 2019 Aug; 130:219-230. PMID: 31078726.
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    69. Edgar RJ, van Hensbergen VP, Ruda A, Turner AG, Deng P, Le Breton Y, El-Sayed NM, Belew AT, McIver KS, McEwan AG, Morris AJ, Lambeau G, Walker MJ, Rush JS, Korotkov KV, Widmalm G, van Sorge NM, Korotkova N. Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides. Nat Chem Biol. 2019 05; 15(5):463-471. PMID: 30936502.
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    70. Hardesty JE, Wahlang B, Falkner KC, Shi H, Jin J, Zhou Y, Wilkey DW, Merchant ML, Watson CT, Feng W, Morris AJ, Hennig B, Prough RA, Cave MC. Proteomic Analysis Reveals Novel Mechanisms by Which Polychlorinated Biphenyls Compromise the Liver Promoting Diet-Induced Steatohepatitis. J Proteome Res. 2019 04 05; 18(4):1582-1594. PMID: 30807179.
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    71. Elhassanny AEM, Ladin DA, Soliman E, Albassam H, Morris A, Kobet R, Thayne K, Burns C, Danell AS, Van Dross R. Prostaglandin D2-ethanolamide induces skin cancer apoptosis by suppressing the activity of cellular antioxidants. Prostaglandins Other Lipid Mediat. 2019 06; 142:9-23. PMID: 30858059.
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    72. Yang L, Kraemer M, Fang XF, Angel PM, Drake RR, Morris AJ, Smyth SS. LPA receptor 4 deficiency attenuates experimental atherosclerosis. J Lipid Res. 2019 05; 60(5):972-980. PMID: 30796085.
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    73. Brandon JA, Kraemer M, Vandra J, Halder S, Ubele M, Morris AJ, Smyth SS. Adipose-derived autotaxin regulates inflammation and steatosis associated with diet-induced obesity. PLoS One. 2019; 14(2):e0208099. PMID: 30730895.
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    74. Deng P, Barney J, Petriello MC, Morris AJ, Wahlang B, Hennig B. Hepatic metabolomics reveals that liver injury increases PCB 126-induced oxidative stress and metabolic dysfunction. Chemosphere. 2019 Feb; 217:140-149. PMID: 30415113.
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    75. Jafari N, Drury J, Morris AJ, Onono FO, Stevens PD, Gao T, Liu J, Wang C, Lee EY, Weiss HL, Evers BM, Zaytseva YY. De Novo Fatty Acid Synthesis-Driven Sphingolipid Metabolism Promotes Metastatic Potential of Colorectal Cancer. Mol Cancer Res. 2019 01; 17(1):140-152. PMID: 30154249.
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    76. Chadid T, Morris A, Surowiec A, Robinson S, Sasaki M, Galipeau J, Pollack BP, Brewster LP. Reversible secretome and signaling defects in diabetic mesenchymal stem cells from peripheral arterial disease patients. J Vasc Surg. 2018 12; 68(6S):137S-151S.e2. PMID: 30104096.
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    77. D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC. Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. J Lipid Res. 2018 10; 59(10):1805-1817. PMID: 30072447.
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    78. Petriello MC, Hoffman JB, Vsevolozhskaya O, Morris AJ, Hennig B. Dioxin-like PCB 126 increases intestinal inflammation and disrupts gut microbiota and metabolic homeostasis. Environ Pollut. 2018 Nov; 242(Pt A):1022-1032. PMID: 30373033.
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    79. Federico L, Yang L, Brandon J, Panchatcharam M, Ren H, Mueller P, Sunkara M, Escalante-Alcalde D, Morris AJ, Smyth SS. Lipid phosphate phosphatase 3 regulates adipocyte sphingolipid synthesis, but not developmental adipogenesis or diet-induced obesity in mice. PLoS One. 2018; 13(6):e0198063. PMID: 29889835.
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    80. Zaytseva YY, Rychahou PG, Le AT, Scott TL, Flight RM, Kim JT, Harris J, Liu J, Wang C, Morris AJ, Sivakumaran TA, Fan T, Moseley H, Gao T, Lee EY, Weiss HL, Heuer TS, Kemble G, Evers M. Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer. Oncotarget. 2018 May 15; 9(37):24787-24800. PMID: 29872506.
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    81. Thalman C, Horta G, Qiao L, Endle H, Tegeder I, Cheng H, Laube G, Sigurdsson T, Hauser MJ, Tenzer S, Distler U, Aoki J, Morris AJ, Geisslinger G, R?per J, Kirischuk S, Luhmann HJ, Radyushkin K, Nitsch R, Vogt J. Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders. Mol Psychiatry. 2018 08; 23(8):1699-1710. PMID: 29743582.
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    82. Lidgerwood GE, Morris AJ, Conquest A, Daniszewski M, Rooney LA, Lim SY, Hern?ndez D, Liang HH, Allen P, Connell PP, Guymer RH, Hewitt AW, P?bay A. Role of lysophosphatidic acid in the retinal pigment epithelium and photoreceptors. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 07; 1863(7):750-761. PMID: 29660533.
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    83. Petriello MC, Brandon JA, Hoffman J, Wang C, Tripathi H, Abdel-Latif A, Ye X, Li X, Yang L, Lee E, Soman S, Barney J, Wahlang B, Hennig B, Morris AJ. Dioxin-like PCB 126 Increases Systemic Inflammation and Accelerates Atherosclerosis in Lean LDL Receptor-Deficient Mice. Toxicol Sci. 2018 04 01; 162(2):548-558. PMID: 29216392.
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    84. Le Saux N, Dalton B, Abbass K, Conly J, Daneman N, Dresser L, Fanella S, German G, Grant J, Keynan Y, Lau TTY, McDonald J, Nott C, Patrick D, Shevchuk Y, Thirion D, Morris A. Funding for Antimicrobial Stewardship Programs: A Customizable Business Case Template. Can J Hosp Pharm. 2018 Jan-Feb; 71(1):50-51. PMID: 29531399.
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    85. Petriello MC, Charnigo R, Sunkara M, Soman S, Pavuk M, Birnbaum L, Morris AJ, Hennig B. Relationship between serum trimethylamine N-oxide and exposure to dioxin-like pollutants. Environ Res. 2018 04; 162:211-218. PMID: 29353125.
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    86. Kraemer MP, Halder S, Smyth SS, Morris AJ. Measurement of Lysophosphatidic Acid and Sphingosine-1-Phosphate by Liquid Chromatography-Coupled Electrospray Ionization Tandem Mass Spectrometry. Methods Mol Biol. 2018; 1697:31-42. PMID: 28770493.
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    87. Tang S, Floy M, Bhandari R, Sunkara M, Morris AJ, Dziubla TD, Hilt JZ. Synthesis and Characterization of Thermoresponsive Hydrogels Based on N-Isopropylacrylamide Crosslinked with 4,4'-Dihydroxybiphenyl Diacrylate. ACS Omega. 2017 Dec 31; 2(12):8723-8729. PMID: 29302630.
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    88. Wahlang B, Barney J, Thompson B, Wang C, Hamad OM, Hoffman JB, Petriello MC, Morris AJ, Hennig B. Editor's Highlight: PCB126 Exposure Increases Risk for Peripheral Vascular Diseases in a Liver Injury Mouse Model. Toxicol Sci. 2017 Dec 01; 160(2):256-267. PMID: 28973532.
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    89. Rush JS, Edgar RJ, Deng P, Chen J, Zhu H, van Sorge NM, Morris AJ, Korotkov KV, Korotkova N. The molecular mechanism of N-acetylglucosamine side-chain attachment to the Lancefield group A carbohydrate in Streptococcus pyogenes. J Biol Chem. 2017 11 24; 292(47):19441-19457. PMID: 29021255.
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    90. Chandra M, Escalante-Alcalde D, Bhuiyan MS, Orr AW, Kevil C, Morris AJ, Nam H, Dominic P, McCarthy KJ, Miriyala S, Panchatcharam M. Cardiac-specific inactivation of LPP3 in mice leads to myocardial dysfunction and heart failure. Redox Biol. 2018 04; 14:261-271. PMID: 28982073.
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    91. Dong A, Mueller P, Yang F, Yang L, Morris A, Smyth SS. Direct thrombin inhibition with dabigatran attenuates pressure overload-induced cardiac fibrosis and dysfunction in mice. Thromb Res. 2017 Nov; 159:58-64. PMID: 28982031.
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    92. Frasinyuk MS, Zhang W, Wyrebek P, Yu T, Xu X, Sviripa VM, Bondarenko SP, Xie Y, Ngo HX, Morris AJ, Mohler JL, Fiandalo MV, Watt DS, Liu C. Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4). Org Biomol Chem. 2017 Sep 20; 15(36):7623-7629. PMID: 28868548.
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    93. Patil VS, Gutierrez AM, Sunkara M, Morris AJ, Hilt JZ, Kalika DS, Dziubla TD. Curcumin Acrylation for Biological and Environmental Applications. J Nat Prod. 2017 07 28; 80(7):1964-1971. PMID: 28661687.
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    94. Dobierzewska A, Soman S, Illanes SE, Morris AJ. Plasma cross-gestational sphingolipidomic analyses reveal potential first trimester biomarkers of preeclampsia. PLoS One. 2017; 12(4):e0175118. PMID: 28384202.
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    95. Song ES, Jang H, Guo HF, Juliano MA, Juliano L, Morris AJ, Galperin E, Rodgers DW, Hersh LB. Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to endosomes. Proc Natl Acad Sci U S A. 2017 04 04; 114(14):E2826-E2835. PMID: 28325868.
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    96. Petriello MC, Hoffman JB, Morris AJ, Hennig B. Emerging roles of xenobiotic detoxification enzymes in metabolic diseases. Rev Environ Health. 2017 Mar 01; 32(1-2):105-110. PMID: 27837601.
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    97. Keune WJ, Potjewyd F, Heidebrecht T, Salgado-Polo F, Macdonald SJ, Chelvarajan L, Abdel Latif A, Soman S, Morris AJ, Watson AJ, Jamieson C, Perrakis A. Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators. J Med Chem. 2017 03 09; 60(5):2006-2017. PMID: 28165241.
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    98. Jafari N, Kim H, Park R, Li L, Jang M, Morris AJ, Park J, Huang C. CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells. PLoS One. 2017; 12(1):e0170327. PMID: 28099519.
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    99. Shaaban KA, Saunders MA, Zhang Y, Tran T, Elshahawi SI, Ponomareva LV, Wang X, Zhang J, Copley GC, Sunkara M, Kharel MK, Morris AJ, Hower JC, Tremblay MS, Prendergast MA, Thorson JS. Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6. J Nat Prod. 2017 01 27; 80(1):2-11. PMID: 28029795.
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    100. Zhang J, Hughes RR, Saunders MA, Elshahawi SI, Ponomareva LV, Zhang Y, Winchester SR, Scott SA, Sunkara M, Morris AJ, Prendergast MA, Shaaban KA, Thorson JS. Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning. J Nat Prod. 2017 01 27; 80(1):12-18. PMID: 28029796.
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    101. Wang X, Maruvada R, Morris AJ, Liu JO, Wolfgang MJ, Baek DJ, Bittman R, Kim KS. Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier. PLoS Pathog. 2016 Oct; 12(10):e1005926. PMID: 27711202.
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    102. Morris AJ, Smyth SS. Regulation of Lysophosphatidic Acid Metabolism and Signaling by Lipoproteins. Arterioscler Thromb Vasc Biol. 2016 10; 36(10):2029-30. PMID: 27655776.
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    103. Huber TD, Wang F, Singh S, Johnson BR, Zhang J, Sunkara M, Van Lanen SG, Morris AJ, Phillips GN, Thorson JS. Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways. ACS Chem Biol. 2016 09 16; 11(9):2484-91. PMID: 27351335.
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    104. Liu M, Verma N, Peng X, Srodulski S, Morris A, Chow M, Hersh LB, Chen J, Zhu H, Netea MG, Margulies KB, Despa S, Despa F. Hyperamylinemia Increases IL-1? Synthesis in the Heart via Peroxidative Sarcolemmal Injury. Diabetes. 2016 09; 65(9):2772-83. PMID: 27335231.
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    105. Mole DJ, Gungabissoon U, Johnston P, Cochrane L, Hopkins L, Wyper GM, Skouras C, Dibben C, Sullivan F, Morris A, Ward HJ, Lawton AM, Donnan PT. Identifying risk factors for progression to critical care admission and death among individuals with acute pancreatitis: a record linkage analysis of Scottish healthcare databases. BMJ Open. 2016 06 15; 6(6):e011474. PMID: 27311912.
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    106. Li J, Song J, Zaytseva YY, Liu Y, Rychahou P, Jiang K, Starr ME, Kim JT, Harris JW, Yiannikouris FB, Katz WS, Nilsson PM, Orho-Melander M, Chen J, Zhu H, Fahrenholz T, Higashi RM, Gao T, Morris AJ, Cassis LA, Fan TW, Weiss HL, Dobner PR, Melander O, Jia J, Evers BM. An obligatory role for neurotensin in high-fat-diet-induced obesity. Nature. 2016 05 19; 533(7603):411-5. PMID: 27193687.
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    107. Keune WJ, Hausmann J, Bolier R, Tolenaars D, Kremer A, Heidebrecht T, Joosten RP, Sunkara M, Morris AJ, Matas-Rico E, Moolenaar WH, Oude Elferink RP, Perrakis A. Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling. Nat Commun. 2016 Apr 14; 7:11248. PMID: 27075612.
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    108. Petriello MC, Hoffman JB, Sunkara M, Wahlang B, Perkins JT, Morris AJ, Hennig B. Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors. J Nutr Biochem. 2016 07; 33:145-53. PMID: 27155921.
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    109. Vogt J, Yang JW, Mobascher A, Cheng J, Li Y, Liu X, Baumgart J, Thalman C, Kirischuk S, Unichenko P, Horta G, Radyushkin K, Stroh A, Richers S, Sahragard N, Distler U, Tenzer S, Qiao L, Lieb K, T?scher O, Binder H, Ferreiros N, Tegeder I, Morris AJ, Gropa S, N?rnberg P, Toliat MR, Winterer G, Luhmann HJ, Huai J, Nitsch R. Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP. EMBO Mol Med. 2016 Jan 01; 8(1):25-38. PMID: 26671989.
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    110. Albayati ZA, Sunkara M, Schmidt-Malan SM, Karau MJ, Morris AJ, Steckelberg JM, Patel R, Breen PJ, Smeltzer MS, Taylor KG, Merten KE, Pierce WM, Crooks PA. Novel Bone-Targeting Agent for Enhanced Delivery of Vancomycin to Bone. Antimicrob Agents Chemother. 2015 Dec 14; 60(3):1865-8. PMID: 26666918.
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    111. Wang X, Reynolds AR, Elshahawi SI, Shaaban KA, Ponomareva LV, Saunders MA, Elgumati IS, Zhang Y, Copley GC, Hower JC, Sunkara M, Morris AJ, Kharel MK, Van Lanen SG, Prendergast MA, Thorson JS. Correction to "Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8". Org Lett. 2015 Nov 06; 17(21):5515. PMID: 26458135.
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    112. Abdel-Latif A, Heron PM, Morris AJ, Smyth SS. Lysophospholipids in coronary artery and chronic ischemic heart disease. Curr Opin Lipidol. 2015 Oct; 26(5):432-7. PMID: 26270808.
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    113. Klyachkin YM, Nagareddy PR, Ye S, Wysoczynski M, Asfour A, Gao E, Sunkara M, Brandon JA, Annabathula R, Ponnapureddy R, Solanki M, Pervaiz ZH, Smyth SS, Ratajczak MZ, Morris AJ, Abdel-Latif A. Pharmacological Elevation of Circulating Bioactive Phosphosphingolipids Enhances Myocardial Recovery After Acute Infarction. Stem Cells Transl Med. 2015 Nov; 4(11):1333-43. PMID: 26371341.
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    114. Zhang W, Deng J, Sunkara M, Morris AJ, Wang C, St Clair D, Vore M. Loss of multidrug resistance-associated protein 1 potentiates chronic doxorubicin-induced cardiac dysfunction in mice. J Pharmacol Exp Ther. 2015 Nov; 355(2):280-7. PMID: 26354995.
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    115. Deng J, Coy D, Zhang W, Sunkara M, Morris AJ, Wang C, Chaiswing L, St Clair D, Vore M, Jungsuwadee P. Elevated glutathione is not sufficient to protect against doxorubicin-induced nuclear damage in heart in multidrug resistance-associated protein 1 (Mrp1/Abcc1) null mice. J Pharmacol Exp Ther. 2015 Nov; 355(2):272-9. PMID: 26354996.
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    116. Wang X, Reynolds AR, Elshahawi SI, Shaaban KA, Ponomareva LV, Saunders MA, Elgumati IS, Zhang Y, Copley GC, Hower JC, Sunkara M, Morris AJ, Kharel MK, Van Lanen SG, Prendergast MA, Thorson JS. Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8. Org Lett. 2015 Jun 05; 17(11):2796-9. PMID: 25961722.
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    117. Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, Van Lanen SG. The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE. J Biol Chem. 2015 May 29; 290(22):13710-24. PMID: 25855790.
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    118. Reschen ME, Gaulton KJ, Lin D, Soilleux EJ, Morris AJ, Smyth SS, O'Callaghan CA. Lipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding. PLoS Genet. 2015 Apr; 11(4):e1005061. PMID: 25835000.
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    119. Mueller P, Ye S, Morris A, Smyth SS. Lysophospholipid mediators in the vasculature. Exp Cell Res. 2015 May 01; 333(2):190-194. PMID: 25825155.
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    120. Walton RG, Zhu B, Unal R, Spencer M, Sunkara M, Morris AJ, Charnigo R, Katz WS, Daugherty A, Howatt DA, Kern PA, Finlin BS. Increasing adipocyte lipoprotein lipase improves glucose metabolism in high fat diet-induced obesity. J Biol Chem. 2015 May 01; 290(18):11547-56. PMID: 25784555.
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    121. Baker NA, Shoemaker R, English V, Larian N, Sunkara M, Morris AJ, Walker M, Yiannikouris F, Cassis LA. Effects of Adipocyte Aryl Hydrocarbon Receptor Deficiency on PCB-Induced Disruption of Glucose Homeostasis in Lean and Obese Mice. Environ Health Perspect. 2015 Oct; 123(10):944-50. PMID: 25734695.
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    122. Siow D, Sunkara M, Dunn TM, Morris AJ, Wattenberg B. ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis. J Lipid Res. 2015 Apr; 56(4):898-908. PMID: 25691431.
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    123. Murphy MO, Petriello MC, Han SG, Sunkara M, Morris AJ, Esser K, Hennig B. Exercise protects against PCB-induced inflammation and associated cardiovascular risk factors. Environ Sci Pollut Res Int. 2016 Feb; 23(3):2201-11. PMID: 25586614.
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    124. Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Ngwa JS, Huikari V, Cavadino A, Nolte IM, Teumer A, Yu K, Marques-Vidal P, Rawal R, Manichaikul A, Wojczynski MK, Vink JM, Zhao JH, Burlutsky G, Lahti J, Mikkil? V, Lemaitre RN, Eriksson J, Musani SK, Tanaka T, Geller F, Luan J, Hui J, M?gi R, Dimitriou M, Garcia ME, Ho WK, Wright MJ, Rose LM, Magnusson PK, Pedersen NL, Couper D, Oostra BA, Hofman A, Ikram MA, Tiemeier HW, Uitterlinden AG, van Rooij FJ, Barroso I, Johansson I, Xue L, Kaakinen M, Milani L, Power C, Snieder H, Stolk RP, Baumeister SE, Biffar R, Gu F, Bastardot F, Kutalik Z, Jacobs DR, Forouhi NG, Mihailov E, Lind L, Lindgren C, Micha?lsson K, Morris A, Jensen M, Khaw KT, Luben RN, Wang JJ, M?nnist? S, Per?l? MM, K?h?nen M, Lehtim?ki T, Viikari J, Mozaffarian D, Mukamal K, Psaty BM, D?ring A, Heath AC, Montgomery GW, Dahmen N, Carithers T, Tucker KL, Ferrucci L, Boyd HA, Melbye M, Treur JL, Mellstr?m D, Hottenga JJ, Prokopenko I, T?njes A, Deloukas P, Kanoni S, Lorentzon M, Houston DK, Liu Y, Danesh J, Rasheed A, Mason MA, Zonderman AB, Franke L, Kristal BS, Karjalainen J, Reed DR, Westra HJ, Evans MK, Saleheen D, Harris TB, Dedoussis G, Curhan G, Stumvoll M, Beilby J, Pasquale LR, Feenstra B, Bandinelli S, Ordovas JM, Chan AT, Peters U, Ohlsson C, Gieger C, Martin NG, Waldenberger M, Siscovick DS, Raitakari O, Eriksson JG, Mitchell P, Hunter DJ, Kraft P, Rimm EB, Boomsma DI, Borecki IB, Loos RJ, Wareham NJ, Vollenweider P, Caporaso N, Grabe HJ, Neuhouser ML, Wolffenbuttel BH, Hu FB, Hypp?nen E, J?rvelin MR, Cupples LA, Franks PW, Ridker PM, van Duijn CM, Heiss G, Metspalu A, North KE, Ingelsson E, Nettleton JA, van Dam RM, Chasman DI. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Mol Psychiatry. 2015 May; 20(5):647-656. PMID: 25288136.
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    125. Morris AJ, Smyth SS. Lipid phosphate phosphatases: more than one way to put the brakes on LPA signaling? J Lipid Res. 2014 Nov; 55(11):2195-7. PMID: 25271297.
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    126. Siow D, Sunkara M, Morris A, Wattenberg B. Regulation of de novo sphingolipid biosynthesis by the ORMDL proteins and sphingosine kinase-1. Adv Biol Regul. 2015 Jan; 57:42-54. PMID: 25319495.
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    127. Jonnalagadda D, Sunkara M, Morris AJ, Whiteheart SW. Granule-mediated release of sphingosine-1-phosphate by activated platelets. Biochim Biophys Acta. 2014 Nov; 1841(11):1581-9. PMID: 25158625.
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    128. Subramanian T, Ren H, Subramanian KL, Sunkara M, Onono FO, Morris AJ, Spielmann HP. Design and synthesis of non-hydrolyzable homoisoprenoid a-monofluorophosphonate inhibitors of PPAPDC family integral membrane lipid phosphatases. Bioorg Med Chem Lett. 2014 Sep 15; 24(18):4414-4417. PMID: 25150376.
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    129. Deevska G, Sunkara M, Karakashian C, Peppers B, Morris AJ, Nikolova-Karakashian MN. Effect of procysteine on aging-associated changes in hepatic GSH and SMase: evidence for transcriptional regulation of smpd3. J Lipid Res. 2014 Oct; 55(10):2041-52. PMID: 25047167.
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    130. Schneider G, Sellers ZP, Abdel-Latif A, Morris AJ, Ratajczak MZ. Bioactive lipids, LPC and LPA, are novel prometastatic factors and their tissue levels increase in response to radio/chemotherapy. Mol Cancer Res. 2014 Nov; 12(11):1560-73. PMID: 25033840.
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    131. Bolton JL, Hayward C, Direk N, Lewis JG, Hammond GL, Hill LA, Anderson A, Huffman J, Wilson JF, Campbell H, Rudan I, Wright A, Hastie N, Wild SH, Velders FP, Hofman A, Uitterlinden AG, Lahti J, R?ikk?nen K, Kajantie E, Widen E, Palotie A, Eriksson JG, Kaakinen M, J?rvelin MR, Timpson NJ, Davey Smith G, Ring SM, Evans DM, St Pourcain B, Tanaka T, Milaneschi Y, Bandinelli S, Ferrucci L, van der Harst P, Rosmalen JG, Bakker SJ, Verweij N, Dullaart RP, Mahajan A, Lindgren CM, Morris A, Lind L, Ingelsson E, Anderson LN, Pennell CE, Lye SJ, Matthews SG, Eriksson J, Mellstrom D, Ohlsson C, Price JF, Strachan MW, Reynolds RM, Tiemeier H, Walker BR. Genome wide association identifies common variants at the SERPINA6/SERPINA1 locus influencing plasma cortisol and corticosteroid binding globulin. PLoS Genet. 2014 Jul; 10(7):e1004474. PMID: 25010111.
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    132. Rajala RV, Rajala A, Morris AJ, Anderson RE. Phosphoinositides: minor lipids make a major impact on photoreceptor cell functions. Sci Rep. 2014 Jun 26; 4:5463. PMID: 24964953.
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    133. Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpel?inen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD, Feitosa MF, Tekola-Ayele F, Chu AY, Nolte IM, Dastani Z, Morris A, Pendergrass SA, Sun YV, Ritchie MD, Vaez A, Lin H, Ligthart S, Marullo L, Rohde R, Shao Y, Ziegler MA, Im HK, Schnabel RB, J?rgensen T, J?rgensen ME, Hansen T, Pedersen O, Stolk RP, Snieder H, Hofman A, Uitterlinden AG, Franco OH, Ikram MA, Richards JB, Rotimi C, Wilson JG, Lange L, Ganesh SK, Nalls M, Rasmussen-Torvik LJ, Pankow JS, Coresh J, Tang W, Linda Kao WH, Boerwinkle E, Morrison AC, Ridker PM, Becker DM, Rotter JI, Kardia SL, Loos RJ, Larson MG, Hsu YH, Province MA, Tracy R, Voight BF, Vaidya D, O'Donnell CJ, Benjamin EJ, Alizadeh BZ, Prokopenko I, Meigs JB, Borecki IB. Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab. 2014 Aug; 112(4):317-38. PMID: 24981077.
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    134. Sui Y, Park SH, Helsley RN, Sunkara M, Gonzalez FJ, Morris AJ, Zhou C. Bisphenol A increases atherosclerosis in pregnane X receptor-humanized ApoE deficient mice. J Am Heart Assoc. 2014 Apr 22; 3(2):e000492. PMID: 24755147.
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    135. Wang X, Shaaban KA, Elshahawi SI, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Mullinamides A and B, new cyclopeptides produced by the Ruth Mullins coal mine fire isolate Streptomyces sp. RM-27-46. J Antibiot (Tokyo). 2014 Aug; 67(8):571-5. PMID: 24713874.
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    136. Wang F, Singh S, Zhang J, Huber TD, Helmich KE, Sunkara M, Hurley KA, Goff RD, Bingman CA, Morris AJ, Thorson JS, Phillips GN. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus?solfataricus. FEBS J. 2014 Sep; 281(18):4224-39. PMID: 24649856.
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    137. Zhang J, Singh S, Hughes RR, Zhou M, Sunkara M, Morris AJ, Thorson JS. A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis. Chembiochem. 2014 Mar 21; 15(5):647-52. PMID: 24677528.
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    138. Singh S, Zhang J, Huber TD, Sunkara M, Hurley K, Goff RD, Wang G, Zhang W, Liu C, Rohr J, Van Lanen SG, Morris AJ, Thorson JS. Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues. Angew Chem Int Ed Engl. 2014 Apr 07; 53(15):3965-9. PMID: 24616228.
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    139. Panchatcharam M, Salous AK, Brandon J, Miriyala S, Wheeler J, Patil P, Sunkara M, Morris AJ, Escalante-Alcalde D, Smyth SS. Mice with targeted inactivation of ppap2b in endothelial and hematopoietic cells display enhanced vascular inflammation and permeability. Arterioscler Thromb Vasc Biol. 2014 Apr; 34(4):837-45. PMID: 24504738.
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    140. Smyth SS, Mueller P, Yang F, Brandon JA, Morris AJ. Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis. Arterioscler Thromb Vasc Biol. 2014 Mar; 34(3):479-86. PMID: 24482375.
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    141. Baker NA, English V, Sunkara M, Morris AJ, Pearson KJ, Cassis LA. Resveratrol protects against polychlorinated biphenyl-mediated impairment of glucose homeostasis in adipocytes. J Nutr Biochem. 2013 Dec; 24(12):2168-74. PMID: 24231106.
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    142. Wu T, Kooi CV, Shah P, Charnigo R, Huang C, Smyth SS, Morris AJ. Integrin-mediated cell surface recruitment of autotaxin promotes persistent directional cell migration. FASEB J. 2014 Feb; 28(2):861-70. PMID: 24277575.
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    143. Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. The native production of the sesquiterpene isopterocarpolone by Streptomyces sp. RM-14-6. Nat Prod Res. 2014; 28(5):337-9. PMID: 24237421.
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    144. Chen X, Rateri DL, Howatt DA, Balakrishnan A, Moorleghen JJ, Morris AJ, Charnigo R, Cassis LA, Daugherty A. Amlodipine reduces AngII-induced aortic aneurysms and atherosclerosis in hypercholesterolemic mice. PLoS One. 2013; 8(11):e81743. PMID: 24244746.
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    145. Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Venturicidin C, a new 20-membered macrolide produced by Streptomyces sp. TS-2-2. J Antibiot (Tokyo). 2014 Mar; 67(3):223-30. PMID: 24252813.
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    146. Stockler-Ipsiroglu S, van Karnebeek C, Longo N, Korenke GC, Mercimek-Mahmutoglu S, Marquart I, Barshop B, Grolik C, Schlune A, Angle B, Ara?jo HC, Coskun T, Diogo L, Geraghty M, Haliloglu G, Konstantopoulou V, Leuzzi V, Levtova A, Mackenzie J, Maranda B, Mhanni AA, Mitchell G, Morris A, Newlove T, Renaud D, Scaglia F, Valayannopoulos V, van Spronsen FJ, Verbruggen KT, Yuskiv N, Nyhan W, Schulze A. Guanidinoacetate methyltransferase (GAMT) deficiency: outcomes in 48 individuals and recommendations for diagnosis, treatment and monitoring. Mol Genet Metab. 2014 Jan; 111(1):16-25. PMID: 24268530.
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    147. Newsome BJ, Petriello MC, Han SG, Murphy MO, Eske KE, Sunkara M, Morris AJ, Hennig B. Green tea diet decreases PCB 126-induced oxidative stress in mice by up-regulating antioxidant enzymes. J Nutr Biochem. 2014 Feb; 25(2):126-35. PMID: 24378064.
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    148. Gilbert MR, Liu Y, Neltner J, Pu H, Morris A, Sunkara M, Pittman T, Kyprianou N, Horbinski C. Autophagy and oxidative stress in gliomas with IDH1 mutations. Acta Neuropathol. 2014 Feb; 127(2):221-33. PMID: 24150401.
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    149. Zhang Y, Wang X, Sunkara M, Ye Q, Ponomereva LV, She QB, Morris AJ, Thorson JS. A diastereoselective oxa-Pictet-Spengler-based strategy for (+)-frenolicin B and epi-(+)-frenolicin B synthesis. Org Lett. 2013 Nov 01; 15(21):5566-9. PMID: 24151973.
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    150. Becker J, Czamara D, Scerri TS, Ramus F, Cs?pe V, Talcott JB, Stein J, Morris A, Ludwig KU, Hoffmann P, Honbolyg? F, T?th D, Fauchereau F, Bogliotti C, Iannuzzi S, Chaix Y, Valdois S, Billard C, George F, Soares-Boucaud I, G?rard CL, van der Mark S, Schulz E, Vaessen A, Maurer U, Lohvansuu K, Lyytinen H, Zucchelli M, Brandeis D, Blomert L, Lepp?nen PH, Bruder J, Monaco AP, M?ller-Myhsok B, Kere J, Landerl K, N?then MM, Schulte-K?rne G, Paracchini S, Peyrard-Janvid M, Schumacher J. Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort. Eur J Hum Genet. 2014 May; 22(5):675-80. PMID: 24022301.
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    151. Shaaban KA, Wang X, Elshahawi SI, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Herbimycins D-F, ansamycin analogues from Streptomyces sp. RM-7-15. J Nat Prod. 2013 Sep 27; 76(9):1619-26. PMID: 23947794.
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    152. Salous AK, Panchatcharam M, Sunkara M, Mueller P, Dong A, Wang Y, Graf GA, Smyth SS, Morris AJ. Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice. J Lipid Res. 2013 Oct; 54(10):2775-84. PMID: 23948545.
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    153. Wang X, Shaaban KA, Elshahawi SI, Ponomareva LV, Sunkara M, Zhang Y, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Frenolicins C-G, pyranonaphthoquinones from Streptomyces sp. RM-4-15. J Nat Prod. 2013 Aug 23; 76(8):1441-7. PMID: 23944931.
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    154. Onono F, Subramanian T, Sunkara M, Subramanian KL, Spielmann HP, Morris AJ. Efficient use of exogenous isoprenols for protein isoprenylation by MDA-MB-231 cells is regulated independently of the mevalonate pathway. J Biol Chem. 2013 Sep 20; 288(38):27444-27455. PMID: 23908355.
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    155. Singh S, Chang A, Helmich KE, Bingman CA, Wrobel RL, Beebe ET, Makino S, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN, Thorson JS. Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis. ACS Chem Biol. 2013 Jul 19; 8(7):1632-9. PMID: 23662776.
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    156. Subramanian T, Subramanian KL, Sunkara M, Onono FO, Morris AJ, Spielmann HP. Syntheses of deuterium labeled prenyldiphosphate and prenylcysteine analogues for in vivo mass spectrometric quantification. J Labelled Comp Radiopharm. 2013 Jun 30; 56(8):370-5. PMID: 24285475.
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    157. Goodson NJ, Smith BH, Hocking LJ, McGilchrist MM, Dominiczak AF, Morris A, Porteous DJ, Goebel A. Cardiovascular risk factors associated with the metabolic syndrome are more prevalent in people reporting chronic pain: results from a cross-sectional general population study. Pain. 2013 Sep; 154(9):1595-1602. PMID: 23707277.
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    158. Schneider G, Bryndza E, Abdel-Latif A, Ratajczak J, Maj M, Tarnowski M, Klyachkin YM, Houghton P, Morris AJ, Vater A, Klussmann S, Kucia M, Ratajczak MZ. Bioactive lipids S1P and C1P are prometastatic factors in human rhabdomyosarcoma, and their tissue levels increase in response to radio/chemotherapy. Mol Cancer Res. 2013 Jul; 11(7):793-807. PMID: 23615526.
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    159. Li X, Zhou Q, Sunkara M, Kutys ML, Wu Z, Rychahou P, Morris AJ, Zhu H, Evers BM, Huang C. Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I ? by HECTD1 regulates focal adhesion dynamics and cell migration. J Cell Sci. 2013 Jun 15; 126(Pt 12):2617-28. PMID: 23572508.
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    160. Morris AJ, Smyth SS. Lysophosphatidic acid and cardiovascular disease: seeing is believing. J Lipid Res. 2013 May; 54(5):1153-5. PMID: 23509404.
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    161. Kim C, Schneider G, Abdel-Latif A, Mierzejewska K, Sunkara M, Borkowska S, Ratajczak J, Morris AJ, Kucia M, Ratajczak MZ. Ceramide-1-phosphate regulates migration of multipotent stromal cells and endothelial progenitor cells--implications for tissue regeneration. Stem Cells. 2013 Mar; 31(3):500-10. PMID: 23193025.
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    162. Karapetyan AV, Klyachkin YM, Selim S, Sunkara M, Ziada KM, Cohen DA, Zuba-Surma EK, Ratajczak J, Smyth SS, Ratajczak MZ, Morris AJ, Abdel-Latif A. Bioactive lipids and cationic antimicrobial peptides as new potential regulators for trafficking of bone marrow-derived stem cells in patients with acute myocardial infarction. Stem Cells Dev. 2013 Jun 01; 22(11):1645-56. PMID: 23282236.
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    163. Xiang B, Zhang G, Guo L, Li XA, Morris AJ, Daugherty A, Whiteheart SW, Smyth SS, Li Z. Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway. Nat Commun. 2013; 4:2657. PMID: 24150174.
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    164. Xiang B, Zhang G, Ren H, Sunkara M, Morris AJ, Gartner TK, Smyth SS, Li Z. The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism. PLoS One. 2012; 7(12):e51037. PMID: 23236426.
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    165. Panchatcharam M, Miriyala S, Salous A, Wheeler J, Dong A, Mueller P, Sunkara M, Escalante-Alcalde D, Morris AJ, Smyth SS. Lipid phosphate phosphatase 3 negatively regulates smooth muscle cell phenotypic modulation to limit intimal hyperplasia. Arterioscler Thromb Vasc Biol. 2013 Jan; 33(1):52-9. PMID: 23104851.
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    166. Mendoza A, Br?art B, Ramos-Perez WD, Pitt LA, Gobert M, Sunkara M, Lafaille JJ, Morris AJ, Schwab SR. The transporter Spns2 is required for secretion of lymph but not plasma sphingosine-1-phosphate. Cell Rep. 2012 Nov 29; 2(5):1104-10. PMID: 23103166.
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    167. Baker NA, Karounos M, English V, Fang J, Wei Y, Stromberg A, Sunkara M, Morris AJ, Swanson HI, Cassis LA. Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese mice. Environ Health Perspect. 2013 Jan; 121(1):105-10. PMID: 23099484.
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    168. Deevska GM, Sunkara M, Morris AJ, Nikolova-Karakashian MN. Characterization of secretory sphingomyelinase activity, lipoprotein sphingolipid content and LDL aggregation in ldlr-/- mice fed on a high-fat diet. Biosci Rep. 2012 Oct; 32(5):479-90. PMID: 22712892.
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    169. Dong A, Sunkara M, Panchatcharam M, Salous A, Selim S, Morris AJ, Smyth SS. Synergistic effect of anemia and red blood cells transfusion on inflammation and lung injury. Adv Hematol. 2012; 2012:924042. PMID: 22919395.
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    170. Gellett AM, Kharel Y, Sunkara M, Morris AJ, Lynch KR. Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases. Biochem Biophys Res Commun. 2012 Jun 15; 422(4):758-63. PMID: 22627129.
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    171. S?nchez-S?nchez R, Morales-L?zaro SL, Baizabal JM, Sunkara M, Morris AJ, Escalante-Alcalde D. Lack of lipid phosphate phosphatase-3 in embryonic stem cells compromises neuronal differentiation and neurite outgrowth. Dev Dyn. 2012 May; 241(5):953-64. PMID: 22434721.
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    172. Liu J, Liang S, Liu X, Brown JA, Newman KE, Sunkara M, Morris AJ, Bhatnagar S, Li X, Pujol A, Graf GA. The absence of ABCD2 sensitizes mice to disruptions in lipid metabolism by dietary erucic acid. J Lipid Res. 2012 Jun; 53(6):1071-9. PMID: 22493092.
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    173. Federico L, Ren H, Mueller PA, Wu T, Liu S, Popovic J, Blalock EM, Sunkara M, Ovaa H, Albers HM, Mills GB, Morris AJ, Smyth SS. Autotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice. Mol Endocrinol. 2012 May; 26(5):786-97. PMID: 22474126.
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    174. Pihlajam?ki J, Lerin C, Kaminska D, Venesmaa S, Itkonen P, Boes T, Floss T, Schroeder J, Dearie F, Crunkhorn S, Burak F, Jimenez-Chillaron JC, Kuulasmaa T, Miettinen P, Park PJ, Nasser I, Zhao Z, Zhang Z, Xu Y, Wurst W, Ren H, Morris AJ, Stamm S, Goldfine AB, Laakso M, Patti ME. Response to Brosch et al. Cell Metab. 2012 Mar 07; 15(3):267-269. PMID: 25960695.
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    175. Cantrell Stanford J, Morris AJ, Sunkara M, Popa GJ, Larson KL, ?zcan S. Sphingosine 1-phosphate (S1P) regulates glucose-stimulated insulin secretion in pancreatic beta cells. J Biol Chem. 2012 Apr 13; 287(16):13457-64. PMID: 22389505.
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    176. Zaytseva YY, Rychahou PG, Gulhati P, Elliott VA, Mustain WC, O'Connor K, Morris AJ, Sunkara M, Weiss HL, Lee EY, Evers BM. Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res. 2012 Mar 15; 72(6):1504-17. PMID: 22266115.
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    177. Sumanasekera C, Kelemen O, Beullens M, Aubol BE, Adams JA, Sunkara M, Morris A, Bollen M, Andreadis A, Stamm S. C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1. Nucleic Acids Res. 2012 May; 40(9):4025-39. PMID: 22210893.
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    178. Selim S, Sunkara M, Salous AK, Leung SW, Berdyshev EV, Bailey A, Campbell CL, Charnigo R, Morris AJ, Smyth SS. Plasma levels of sphingosine 1-phosphate are strongly correlated with haematocrit, but variably restored by red blood cell transfusions. Clin Sci (Lond). 2011 Dec; 121(12):565-72. PMID: 21749329.
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    179. Cheng HY, Dong A, Panchatcharam M, Mueller P, Yang F, Li Z, Mills G, Chun J, Morris AJ, Smyth SS. Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling. Arterioscler Thromb Vasc Biol. 2012 Jan; 32(1):24-32. PMID: 22015657.
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    180. Secor JD, Kotha SR, Gurney TO, Patel RB, Kefauver NR, Gupta N, Morris AJ, Haley BE, Parinandi NL. Novel lipid-soluble thiol-redox antioxidant and heavy metal chelator, N,N'-bis(2-mercaptoethyl)isophthalamide (NBMI) and phospholipase D-specific inhibitor, 5-fluoro-2-indolyl des-chlorohalopemide (FIPI) attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. Int J Toxicol. 2011 Dec; 30(6):619-38. PMID: 21994240.
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    181. Zhang G, Xiang B, Ye S, Chrzanowska-Wodnicka M, Morris AJ, Gartner TK, Whiteheart SW, White GC, Smyth SS, Li Z. Distinct roles for Rap1b protein in platelet secretion and integrin aIIb?3 outside-in signaling. J Biol Chem. 2011 Nov 11; 286(45):39466-77. PMID: 21940635.
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    182. Wu Z, Li X, Sunkara M, Spearman H, Morris AJ, Huang C. PIPKI? regulates focal adhesion dynamics and colon cancer cell invasion. PLoS One. 2011; 6(9):e24775. PMID: 21931851.
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    183. Fulkerson Z, Wu T, Sunkara M, Kooi CV, Morris AJ, Smyth SS. Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells. J Biol Chem. 2011 Oct 07; 286(40):34654-63. PMID: 21832043.
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    184. Zheng Y, Morris A, Sunkara M, Layne J, Toborek M, Hennig B. Epigallocatechin-gallate stimulates NF-E2-related factor and heme oxygenase-1 via caveolin-1 displacement. J Nutr Biochem. 2012 Feb; 23(2):163-8. PMID: 21447442.
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    185. Hausmann J, Kamtekar S, Christodoulou E, Day JE, Wu T, Fulkerson Z, Albers HM, van Meeteren LA, Houben AJ, van Zeijl L, Jansen S, Andries M, Hall T, Pegg LE, Benson TE, Kasiem M, Harlos K, Kooi CW, Smyth SS, Ovaa H, Bollen M, Morris AJ, Moolenaar WH, Perrakis A. Structural basis of substrate discrimination and integrin binding by autotaxin. Nat Struct Mol Biol. 2011 Feb; 18(2):198-204. PMID: 21240271.
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    186. L?pez-Ju?rez A, Morales-L?zaro S, S?nchez-S?nchez R, Sunkara M, Lomel? H, Velasco I, Morris AJ, Escalante-Alcalde D. Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development. Glia. 2011 Apr; 59(4):577-89. PMID: 21319224.
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    187. Majkova Z, Layne J, Sunkara M, Morris AJ, Toborek M, Hennig B. Omega-3 fatty acid oxidation products prevent vascular endothelial cell activation by coplanar polychlorinated biphenyls. Toxicol Appl Pharmacol. 2011 Feb 15; 251(1):41-9. PMID: 21130106.
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    188. Ren H, Federico L, Huang H, Sunkara M, Drennan T, Frohman MA, Smyth SS, Morris AJ. A phosphatidic acid binding/nuclear localization motif determines lipin1 function in lipid metabolism and adipogenesis. Mol Biol Cell. 2010 Sep 15; 21(18):3171-81. PMID: 20660155.
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    189. Mathews TP, Kennedy AJ, Kharel Y, Kennedy PC, Nicoara O, Sunkara M, Morris AJ, Wamhoff BR, Lynch KR, Macdonald TL. Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitors. J Med Chem. 2010 Apr 08; 53(7):2766-78. PMID: 20205392.
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    190. Albers HM, Dong A, van Meeteren LA, Egan DA, Sunkara M, van Tilburg EW, Schuurman K, van Tellingen O, Morris AJ, Smyth SS, Moolenaar WH, Ovaa H. Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7257-62. PMID: 20360563.
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    191. Panchatcharam M, Miriyala S, Yang F, Leitges M, Chrzanowska-Wodnicka M, Quilliam LA, Anaya P, Morris AJ, Smyth SS. Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by beta3 integrin signaling. Int J Biochem Cell Biol. 2010 Jun; 42(6):965-74. PMID: 20184965.
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    192. Boyanovsky BB, Li X, Shridas P, Sunkara M, Morris AJ, Webb NR. Bioactive products generated by group V sPLA(2) hydrolysis of LDL activate macrophages to secrete pro-inflammatory cytokines. Cytokine. 2010 Apr; 50(1):50-7. PMID: 20138782.
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    193. Miriyala S, Subramanian T, Panchatcharam M, Ren H, McDermott MI, Sunkara M, Drennan T, Smyth SS, Spielmann HP, Morris AJ. Functional characterization of the atypical integral membrane lipid phosphatase PDP1/PPAPDC2 identifies a pathway for interconversion of isoprenols and isoprenoid phosphates in mammalian cells. J Biol Chem. 2010 Apr 30; 285(18):13918-29. PMID: 20110354.
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    194. Morris AJ, Selim S, Salous A, Smyth SS. Blood relatives: dynamic regulation of bioactive lysophosphatidic acid and sphingosine-1-phosphate metabolism in the circulation. Trends Cardiovasc Med. 2009 May; 19(4):135-40. PMID: 19818950.
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    195. Pamuklar Z, Federico L, Liu S, Umezu-Goto M, Dong A, Panchatcharam M, Fulkerson Z, Fulerson Z, Berdyshev E, Natarajan V, Fang X, van Meeteren LA, Moolenaar WH, Mills GB, Morris AJ, Smyth SS. Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis. J Biol Chem. 2009 Mar 13; 284(11):7385-94. PMID: 19139100.
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    196. Panchatcharam M, Miriyala S, Yang F, Rojas M, End C, Vallant C, Dong A, Lynch K, Chun J, Morris AJ, Smyth SS. Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure. Circ Res. 2008 Sep 12; 103(6):662-70. PMID: 18703779.
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    197. Federico L, Pamuklar Z, Smyth SS, Morris AJ. Therapeutic potential of autotaxin/lysophospholipase d inhibitors. Curr Drug Targets. 2008 Aug; 9(8):698-708. PMID: 18691016.
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    198. Smyth SS, Cheng HY, Miriyala S, Panchatcharam M, Morris AJ. Roles of lysophosphatidic acid in cardiovascular physiology and disease. Biochim Biophys Acta. 2008 Sep; 1781(9):563-70. PMID: 18586114.
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    199. Pamuklar Z, Lee JS, Cheng HY, Panchatcharam M, Steinhubl S, Morris AJ, Charnigo R, Smyth SS. Individual heterogeneity in platelet response to lysophosphatidic acid: evidence for a novel inhibitory pathway. Arterioscler Thromb Vasc Biol. 2008 Mar; 28(3):555-61. PMID: 18202325.
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    200. Morris AJ, Smyth SS. Measurement of autotaxin/lysophospholipase D activity. Methods Enzymol. 2007; 434:89-104. PMID: 17954243.
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    201. McDermott MI, Sigal YJ, Crump JS, Morris AJ. Enzymatic analysis of lipid phosphate phosphatases. Methods. 2006 Jun; 39(2):169-79. PMID: 16815033.
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    202. Grab LT, Kearns MW, Morris AJ, Daniel LW. Differential role for phospholipase D1 and phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate-stimulated MAPK activation, Cox-2 and IL-8 expression. Biochim Biophys Acta. 2004 Feb 27; 1636(1):29-39. PMID: 14984736.
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    203. Smyth SS, Sciorra VA, Sigal YJ, Pamuklar Z, Wang Z, Xu Y, Prestwich GD, Morris AJ. Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity. J Biol Chem. 2003 Oct 31; 278(44):43214-23. PMID: 12909631.
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    204. Luquain C, Sciorra VA, Morris AJ. Lysophosphatidic acid signaling: how a small lipid does big things. Trends Biochem Sci. 2003 Jul; 28(7):377-83. PMID: 12878005.
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    205. Luquain C, Singh A, Wang L, Natarajan V, Morris AJ. Role of phospholipase D in agonist-stimulated lysophosphatidic acid synthesis by ovarian cancer cells. J Lipid Res. 2003 Oct; 44(10):1963-75. PMID: 12837850.
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