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Eric Peterson

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPharmacology & Toxicology, College of Medicine
AddressB110A Biomedical Research I
325 S. Elm St.
Mail Slot # 611
Little Rock AR 72205
Phone501-686-7335
ORCID ORCID Icon0000-0002-1420-2346 Additional info
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    Other Positions
    TitleAssistant Professor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentBiomedical Informatics, College of Medicine

    Other Roles
    Interim President BioVentures LLC

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    MB23OBD0340328     (PETERSON, ERIC C)Sep 1, 2023 - Aug 31, 2027
    US Department of Commerce
    Arkansas Collaborative for Technological and Innovative Venture Equality (ACTIVE)
    Role: Principal Investigator
    Barton FY19     (EOFF, ROBERT L)Feb 1, 2019 - Jan 31, 2020
    UAMS College of Medicine
    No FP attached
    Role: Principal Investigator
    R21DA041822     (TACKETT, ALAN)Jul 1, 2016 - Jun 30, 2019
    NIH
    Technology for Identification of Epiproteomes in Tissue Samples
    Role: Co-Investigator
    117-1006219     (PETERSON, ERIC C)Jul 1, 2015 - Jun 30, 2016
    UAMS College of Medicine
    No FP attached
    Role: Principal Investigator
    R01DA039195     (OWENS, SAMUEL)Apr 15, 2015 - Aug 31, 2019
    NIH/Nat. Inst. on Drug Abuse
    Pharmacology and Therapy for MDPV and alpha-PVP Like Drugs of Abuse
    Role: Co-Investigator
    R01DA036600     (PETERSON, ERIC C)Jul 1, 2014 - Jun 30, 2019
    NIH
    Antibody Gene Therapy for Methamphetamine Abuse
    Role: Principal Investigator
    R01DA026423     (PETERSON, ERIC C)Apr 1, 2009 - Mar 31, 2014
    NIH
    Antibody-nanoparticle conjugates for the treatment of methamphetamine abuse
    Role: Principal Investigator
    U01DA023900     (OWENS, SAMUEL)Sep 30, 2007 - Aug 31, 2013
    NIH/Nat. Inst. on Drug Abuse
    Active Immunization for Treating Methamphetamine Abuse
    Role: Co-Investigator
    F32DA018039     (PETERSON, ERIC C)Sep 5, 2004 - Sep 4, 2007
    NIH
    Single Chain Antibody Medications for(+)METH Abuse
    Role: Principal Investigator
    R01DA011560     (OWENS, SAMUEL)Jan 5, 1998 - Mar 31, 2012
    NIH/Nat. Inst. on Drug Abuse
    Antibody-based Therapy for Methamphetamine Abuse
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Janganati V, Salazar P, Parks BJ, Gorman GS, Prather PL, Peterson EC, Alund AW, Moran JH, Crooks PA, Brents LK. Deuterated buprenorphine retains pharmacodynamic properties of buprenorphine and resists metabolism to the active metabolite norbuprenorphine in rats. Front Pharmacol. 2023; 14:1123261. PMID: 37229250.
      View in: PubMed
    2. Scott XO, Chen SH, Hadad R, Yavagal D, Peterson EC, Starke RM, Dietrich WD, Keane RW, de Rivero Vaccari JP. Cohort study on the differential expression of inflammatory and angiogenic factors in thrombi, cerebral and peripheral plasma following acute large vessel occlusion stroke. J Cereb Blood Flow Metab. 2022 10; 42(10):1827-1839. PMID: 35673992.
      View in: PubMed
    3. Mack JM, Peterson EC, Crary SE, Moran JH, Neville K, Pierce CD, Richter GT. Pharmacokinetics of bleomycin sclerotherapy in patients with vascular malformations. Pediatr Blood Cancer. 2022 08; 69(8):e29733. PMID: 35484878.
      View in: PubMed
    4. McGill MR, James LP, McCullough SS, Moran JH, Mathews SE, Peterson EC, Fleming DP, Tripod ME, Vazquez JH, Kennon-McGill S, Spencer HJ, Dranoff JA. Short-Term Safety of Repeated Acetaminophen Use in Patients With Compensated Cirrhosis. Hepatol Commun. 2022 02; 6(2):361-373. PMID: 34558847.
      View in: PubMed
    5. Chappell K, Graw S, Washam CL, Storey AJ, Bolden C, Peterson EC, Byrum SD. PTMViz: a tool for analyzing and visualizing histone post translational modification data. BMC Bioinformatics. 2021 May 26; 22(1):275. PMID: 34039258.
      View in: PubMed
    6. Chen SH, Scott XO, Ferrer Marcelo Y, Almeida VW, Blackwelder PL, Yavagal DR, Peterson EC, Starke RM, Dietrich WD, Keane RW, de Rivero Vaccari JP. Netosis and Inflammasomes in Large Vessel Occlusion Thrombi. Front Pharmacol. 2020; 11:607287. PMID: 33569001.
      View in: PubMed
    7. Li W, Chen C, Drelich A, Martinez DR, Gralinski LE, Sun Z, Sch?fer A, Kulkarni SS, Liu X, Leist SR, Zhelev DV, Zhang L, Kim YJ, Peterson EC, Conard A, Mellors JW, Tseng CK, Falzarano D, Baric RS, Dimitrov DS. Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2020 11 24; 117(47):29832-29838. PMID: 33139569.
      View in: PubMed
    8. Graw S, Tang J, Zafar MK, Byrd AK, Bolden C, Peterson EC, Byrum SD. proteiNorm - A User-Friendly Tool for Normalization and Analysis of TMT and Label-Free Protein Quantification. ACS Omega. 2020 Oct 13; 5(40):25625-25633. PMID: 33073088.
      View in: PubMed
    9. Li W, Sch?fer A, Kulkarni SS, Liu X, Martinez DR, Chen C, Sun Z, Leist SR, Drelich A, Zhang L, Ura ML, Berezuk A, Chittori S, Leopold K, Mannar D, Srivastava SS, Zhu X, Peterson EC, Tseng CT, Mellors JW, Falzarano D, Subramaniam S, Baric RS, Dimitrov DS. High Potency of a Bivalent Human VH Domain in SARS-CoV-2 Animal Models. Cell. 2020 10 15; 183(2):429-441.e16. PMID: 32941803.
      View in: PubMed
    10. Khan NR, Peterson J, Dornbos Iii D, Nguyen V, Goyal N, Torabi R, Hoit D, Elijovich L, Inoa-Acosta V, Morris D, Nickele C, Jabbour P, Peterson EC, Arthur AS. Predicting the degree of difficulty of the trans-radial approach in cerebral angiography. J Neurointerv Surg. 2021 Jun; 13(6):552-558. PMID: 32792364.
      View in: PubMed
    11. Hay CE, Ewing LE, Hambuchen MD, Zintner SM, Small JC, Bolden CT, Fantegrossi WE, Margaritis P, Owens SM, Peterson EC. The Development and Characterization of an scFv-Fc Fusion-Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine Abuse. J Pharmacol Exp Ther. 2020 07; 374(1):16-23. PMID: 32245884.
      View in: PubMed
    12. Srinivasan VM, Hadley CC, Prablek M, LoPresti M, Chen SH, Peterson EC, Sweid A, Jabbour P, Young C, Levitt M, Osbun JW, Burkhardt JK, Johnson J, Kan P. Feasibility and safety of transradial access for pediatric neurointerventions. J Neurointerv Surg. 2020 Sep; 12(9):893-896. PMID: 32241922.
      View in: PubMed
    13. Almallouhi E, Al Kasab S, Sattur MG, Lena J, Jabbour PM, Sweid A, Chalouhi N, Gooch MR, Starke RM, Peterson EC, Yavagal DR, Chen SH, Li Y, Gross BA, Tonetti DA, Zussman BM, Stone JG, Jadhav AP, Jankowitz BT, Young CC, Lim DH, Levitt MR, Osbun JW, Spiotta AM. Incorporation of transradial approach in neuroendovascular procedures: defining benchmarks for rates of complications and conversion to femoral access. J Neurointerv Surg. 2020 Nov; 12(11):1122-1126. PMID: 32217626.
      View in: PubMed
    14. McClenahan SJ, Kormos CM, Gunnell M, Hambuchen MD, Lamb P, Carroll FI, Lewin AH, Peterson EC, Owens SM. Design, synthesis and biological evaluation of a bi-specific vaccine against a-pyrrolidinovalerophenone (a-PVP) and 3,4-methylenedioxypyrovalerone (MDPV) in rats. Vaccine. 2020 01 10; 38(2):336-344. PMID: 31629568.
      View in: PubMed
    15. Chen SH, McCarthy DJ, Sheinberg D, Hanel R, Sur S, Jabbour P, Atallah E, Chalouhi N, Dumont A, Amenta P, Hasan D, Raper D, Liu K, Jane JA, Crowley RW, Aguilar-Salinas P, Bentley J, Monteith S, Mitchell BD, Yavagal DR, Peterson EC, Starke RM. Pipeline Embolization Device for the Treatment of Intracranial Pseudoaneurysms. World Neurosurg. 2019 Jul; 127:e86-e93. PMID: 30849553.
      View in: PubMed
    16. Brunet MC, Chen SH, Sur S, McCarthy DJ, Snelling B, Yavagal DR, Starke RM, Peterson EC. Distal transradial access in the anatomical snuffbox for diagnostic cerebral angiography. J Neurointerv Surg. 2019 Jul; 11(7):710-713. PMID: 30814329.
      View in: PubMed
    17. Chen SH, Snelling BM, Shah SS, Sur S, Brunet MC, Starke RM, Yavagal DR, Osbun JW, Peterson EC. Transradial approach for flow diversion treatment of cerebral aneurysms: a multicenter study. J Neurointerv Surg. 2019 Aug; 11(8):796-800. PMID: 30670622.
      View in: PubMed
    18. Snelling BM, Sur S, Shah SS, Chen S, Menaker SA, McCarthy DJ, Yavagal DR, Peterson EC, Starke RM. Unfavorable Vascular Anatomy Is Associated with Increased Revascularization Time and Worse Outcome in Anterior Circulation Thrombectomy. World Neurosurg. 2018 Dec; 120:e976-e983. PMID: 30196176.
      View in: PubMed
    19. Hay CE, Gonzalez GA, Ewing LE, Reichard EE, Hambuchen MD, Nanaware-Kharade N, Alam S, Bolden CT, Owens SM, Margaritis P, Peterson EC. Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse. PLoS One. 2018; 13(6):e0200060. PMID: 29958300.
      View in: PubMed
    20. Sheinberg DL, McCarthy DJ, Peterson EC, Starke RM. DEFUSE-3 Trial: Reinforcing Evidence for Extended Endovascular Intervention Time Window for Ischemic Stroke. World Neurosurg. 2018 Apr; 112:275-276. PMID: 29458184.
      View in: PubMed
    21. Avnir Y, Prachanronarong KL, Zhang Z, Hou S, Peterson EC, Sui J, Zayed H, Kurella VB, McGuire AT, Stamatatos L, Hilbert BJ, Bohn MF, Kowalik TF, Jensen JD, Finberg RW, Wang JP, Goodall M, Jefferis R, Zhu Q, Kurt Yilmaz N, Schiffer CA, Marasco WA. Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope. Cell Rep. 2017 Dec 12; 21(11):3243-3255. PMID: 29241550.
      View in: PubMed
    22. Menaker SA, Shah SS, Snelling BM, Sur S, Starke RM, Peterson EC. Current applications and future perspectives of robotics in cerebrovascular and endovascular neurosurgery. J Neurointerv Surg. 2018 Jan; 10(1):78-82. PMID: 28821626.
      View in: PubMed
    23. Reichard EE, Nanaware-Kharade N, Gonzalez GA, Thakkar S, Owens SM, Peterson EC. PEGylation of a High-Affinity Anti-(+)Methamphetamine Single Chain Antibody Fragment Extends Functional Half-Life by Reducing Clearance. Pharm Res. 2016 12; 33(12):2954-2966. PMID: 27620175.
      View in: PubMed
    24. Peterson EC, Ewing LE. Nanomedicine: Going small to beat the high. Nat Nanotechnol. 2016 07; 11(7):580-1. PMID: 26974956.
      View in: PubMed
    25. Hanak BW, Haussen DC, Ambekar S, Ferreira M, Ghodke BV, Peterson EC. Preoperative embolization of intracranial hemangiopericytomas: case series and introduction of the transtumoral embolization technique. J Neurointerv Surg. 2016 Oct; 8(10):1084-94. PMID: 26475475.
      View in: PubMed
    26. Ambekar S, Gaynor BG, Peterson EC, Elhammady MS. Long-term angiographic results of endovascularly "cured" intracranial dural arteriovenous fistulas. J Neurosurg. 2016 Apr; 124(4):1123-7. PMID: 26406789.
      View in: PubMed
    27. Gaynor BG, Haussen DC, Ambekar S, Peterson EC, Yavagal DR, Elhammady MS. Covered Stents for the Prevention and Treatment of Carotid Blowout Syndrome. Neurosurgery. 2015 Aug; 77(2):164-7. PMID: 25790070.
      View in: PubMed
    28. Nanaware-Kharade N, Thakkar S, Gonzalez GA, Peterson EC. A Nanotechnology-Based Platform for Extending the Pharmacokinetic and Binding Properties of Anti-methamphetamine Antibody Fragments. Sci Rep. 2015 Jul 10; 5:12060. PMID: 26159352.
      View in: PubMed
    29. Peterson EC, Hambuchen MD, Tawney RL, Gunnell MG, Cowell JL, Lay JO, Blough BE, Carroll FI, Owens SM. Simple radiometric method for accurately quantitating epitope densities of hapten-protein conjugates with sulfhydryl linkages. Bioconjug Chem. 2014 Dec 17; 25(12):2112-5. PMID: 25426820.
      View in: PubMed
    30. Thakkar S, Nanaware-Kharade N, Celikel R, Peterson EC, Varughese KI. Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering. Sci Rep. 2014 Jan 14; 4:3673. PMID: 24419156.
      View in: PubMed
    31. Peterson EC, Gentry WB, Owens SM. Customizing monoclonal antibodies for the treatment of methamphetamine abuse: current and future applications. Adv Pharmacol. 2014; 69:107-27. PMID: 24484976.
      View in: PubMed
    32. Peterson EC, Celikel R, Gokulan K, Varughese KI. Structural characterization of a therapeutic anti-methamphetamine antibody fragment: oligomerization and binding of active metabolites. PLoS One. 2013; 8(12):e82690. PMID: 24349338.
      View in: PubMed
    33. Nanaware-Kharade N, Gonzalez GA, Lay JO, Hendrickson HP, Peterson EC. Therapeutic anti-methamphetamine antibody fragment-nanoparticle conjugates: synthesis and in vitro characterization. Bioconjug Chem. 2012 Sep 19; 23(9):1864-72. PMID: 22873701.
      View in: PubMed
    34. Nanware-Kharade N, Guilermo A. Gonzalez III, Jackson O. Lay Jr., Howard P. Hendrickson, Eric C. Peterson. Theraputic Anti-Methamphetamine Antibody Fragment-Nanoparticle Conjugates: Synthesis and In Vitro Characterization. Bioconjug Chem. 2012; 23(9):1864-72, PMID 22873701.
    35. EC Peterson, WB Gentry, SM Owens. Customizing Monoclonal Antibodies for the Treatment of Methamphetamine Abuse: Current and Future Apllications. Advances in Pharmacology. 2012.
    36. Owens SM, Atchley WT, Hambuchen MD, Peterson EC, Gentry WB. Monoclonal antibodies as pharmacokinetic antagonists for the treatment of (+)-methamphetamine addiction. CNS Neurol Disord Drug Targets. 2011 Dec; 10(8):892-8. PMID: 22229314.
      View in: PubMed
    37. Elhammady MS, Peterson EC, Johnson JN, Aziz-Sultan MA. Preoperative onyx embolization of vascular head and neck tumors by direct puncture. World Neurosurg. 2012 May-Jun; 77(5-6):725-30. PMID: 22079824.
      View in: PubMed
    38. Carroll FI, Blough BE, Pidaparthi RR, Abraham P, Gong PK, Deng L, Huang X, Gunnell M, Lay JO, Peterson EC, Owens SM. Synthesis of mercapto-(+)-methamphetamine haptens and their use for obtaining improved epitope density on (+)-methamphetamine conjugate vaccines. J Med Chem. 2011 Jul 28; 54(14):5221-8. PMID: 21682289.
      View in: PubMed
    39. Peterson EC, Elhammady MS, Quintero-Wolfe S, Murray TG, Aziz-Sultan MA. Selective ophthalmic artery infusion of chemotherapy for advanced intraocular retinoblastoma: initial experience with 17 tumors. J Neurosurg. 2011 Jun; 114(6):1603-8. PMID: 21294621.
      View in: PubMed
    40. DeKeyser JG, Laurenzana EM, Peterson EC, Chen T, Omiecinski CJ. Selective phthalate activation of naturally occurring human constitutive androstane receptor splice variants and the pregnane X receptor. Toxicol Sci. 2011 Apr; 120(2):381-91. PMID: 21227907.
      View in: PubMed
    41. Owens SM, Atchley WT, Hambuchen MD, E. Peterson, Gentry WB. Monoclonal antibodies as pharmacokinetics antagonists for the treatment of (+)-methamphetamine addiction. CNS Neurol Disord Drug Targets. 2011; 10(8):892-898, PMID 22229314.
    42. Carroll FI, Abraham P, Gong PK, Pidaparthi RR, Blough BE, Che Y, Hampton A, Gunnell M, Lay JO, Peterson EC, Owens SM. The synthesis of haptens and their use for the development of monoclonal antibodies for treating methamphetamine abuse. J Med Chem. 2009 Nov 26; 52(22):7301-9. PMID: 19877685.
      View in: PubMed
    43. Celikel R, Peterson EC, Owens SM, Varughese KI. Crystal structures of a therapeutic single chain antibody in complex with two drugs of abuse-Methamphetamine and 3,4-methylenedioxymethamphetamine. Protein Sci. 2009 Nov; 18(11):2336-45. PMID: 19760665.
      View in: PubMed
    44. Celikel R, EC Peterson, SM Owens, KI Varughese. High Resolution Crystal Structures of a Therapeutic Single Chain Antibody in Complex with two Drugs of Abuse – methamphetamine and 3,4 methylenedioxy-N-methamphetamine. Protein Sci. 2009; 18(11):2336-45, PMID 19760665.
    45. Laurenzana EM, HP Hendrickson, D Carpenter, EC Peterson, WB Gentry, CM West, FI Carroll, SM Owens. Functional and Biological Determinants of the Time Course of Action of Anti-(+)-Methamphetamine Monoclonal Antibodies in Rats. Vaccine. 2009; 27(50):7011-20, PMID 19800446.
    46. Laurenzana EM, Hendrickson HP, Carpenter D, Peterson EC, Gentry WB, West M, Che Y, Carroll FI, Owens SM. Functional and biological determinants affecting the duration of action and efficacy of anti-(+)-methamphetamine monoclonal antibodies in rats. Vaccine. 2009 Nov 23; 27(50):7011-20. PMID: 19800446.
      View in: PubMed
    47. Peterson EC, Owens SM. Designing immunotherapies to thwart drug abuse. Mol Interv. 2009 Jun; 9(3):119-24. PMID: 19592672.
      View in: PubMed
    48. Peterson EC, Laurenzana EM, Atchley WT, Hendrickson HP, Owens SM. Development and preclinical testing of a high-affinity single-chain antibody against (+)-methamphetamine. J Pharmacol Exp Ther. 2008 Apr; 325(1):124-33. PMID: 18192498.
      View in: PubMed
    49. Peterson EC, Henry RL, Owens SM. Drug Addiction: From Basic Research to Therapy. Monoclonal Antibody Form and Function: Manufacturing the Right Antibodies for Treating Drug Abuse. 2008; 5.
    50. Peterson EC, Gunnell M, Che Y, Goforth RL, Carroll FI, Henry R, Liu H, Owens SM. Using hapten design to discover therapeutic monoclonal antibodies for treating methamphetamine abuse. J Pharmacol Exp Ther. 2007 Jul; 322(1):30-9. PMID: 17452421.
      View in: PubMed
    51. Goforth RL, Peterson EC, Yuan J, Moore MJ, Kight AD, Lohse MB, Sakon J, Henry RL. Regulation of the GTPase cycle in post-translational signal recognition particle-based protein targeting involves cpSRP43. J Biol Chem. 2004 Oct 08; 279(41):43077-84. PMID: 15292240.
      View in: PubMed
    52. Yuan J, Kight A, Goforth RL, Moore M, Peterson EC, Sakon J, Henry R. ATP stimulates signal recognition particle (SRP)/FtsY-supported protein integration in chloroplasts. J Biol Chem. 2002 Aug 30; 277(35):32400-4. PMID: 12105232.
      View in: PubMed
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