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Ruofei Du

TitleAssistant Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentBiostatistics, College of Public Health
Address3218 ED III
4301 W. Markham
Mail Slot # 781
Little Rock AR 72205
Phone501-686-5353
Fax501-526-6729
ORCID ORCID Icon0000-0002-0143-5343 Additional info
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    Other Positions
    TitleAssistant Professor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentBiostatistics, College of Medicine
    DivisionBiostatistics Faculty


    Collapse Research 
    Collapse research activities and funding
    6922-03-COVID-S016     (MCELFISH, PEARL A)Apr 1, 2024 - Mar 31, 2028
    Westat - Pass Through: Westat
    FOOD AS MEDICINE: ADDRESSING SOCIAL DETERMINANTS OF HEALTH (FOOD INSECURITY) TO EFFECT CLINICAL OUTCOMES (CEAL)
    Role: Co-Investigator
    SUB-OTA No. 6922-03-COVID-S016     (MCELFISH, PEARL A)Jul 16, 2023 - Mar 31, 2024
    NIH/Nat. Heart, Lung & Blood Institute - Pass Through: Westat
    Community Engagement Research Alliance (CEAL) 2023-2024 Renewal
    Role: Other Key Personnel
    2P42ES025589     (DU, RUOFEI)Sep 20, 2022 - Jun 30, 2027
    NIH/Nat. Inst. of Environmental Health Sciences - Pass Through: University of New Mexico
    UNM Metal Exposure Toxicity Assessment on Tribal Lands in the Southwest (METALS) Superfund Research Program
    Role: Principal Investigator
    2P42ES025589-06     (DU, RUOFEI)Sep 20, 2022 - Jun 30, 2027
    NIH/Nat. Inst. of Environmental Health Sciences - Pass Through: University of New Mexico
    UNM Metal Exposure Toxicity Assessment on Tribal Lands in the Southwest (METALS) Superfund Research Program
    Role: Principal Investigator
    5P42ES025589-08     (DU, RUOFEI)Sep 20, 2022 - Jun 30, 2027
    NIH/Nat. Inst. of Environmental Health Sciences - Pass Through: University of New Mexico
    UNM Metal Exposure Toxicity Assessment on Tribal Lands in the Southwest (METALS) Superfund Research Program
    Role: Principal Investigator
    P42ES025589     (DU, RUOFEI)Sep 20, 2022 - Jun 30, 2027
    NIH/Nat. Inst. of Environmental Health Sciences - Pass Through: University of New Mexico
    UNM Metal Exposure Toxicity Assessment on Tribal Lands in the Southwest (METALS) Superfund Research Program
    Role: Principal Investigator
    U01AI170039     (PATHAK, RUPAK)Jul 25, 2022 - May 31, 2027
    NIH
    Platelets in radiation-induced immune dysregulation
    Role: Co-Investigator
    P50MD017319     (CORNELL, CAROL ELLEN)Sep 24, 2021 - Jun 30, 2026
    NIH
    The Center for Research, Health, and Social Justice
    Role: Co-Investigator
    80NSSC21M0323     (PATHAK, RUPAK)Aug 15, 2021 - Aug 14, 2025
    National Aeronautics & Space Administration - Pass Through: Arkansas Space Grant Consortium
    Preventing immune system dysregulation during deep-space missions by Tocofexol, a modified isomer of vitamin E - AA request
    Role: Other Key Personnel
    P50MD015706     (DU, RUOFEI)Apr 1, 2021 - Mar 31, 2025
    NIH/National Center on Minority Health and Health Disparities - Pass Through: University of New Mexico
    Center for Native American Environmental Health Equity Research
    Role: Principal Investigator
    5P42ES025589-05     (DU, RUOFEI)Apr 1, 2021 - Mar 31, 2022
    NIH/Nat. Inst. of Environmental Health Sciences - Pass Through: University of New Mexico
    UNM Metal Exposure Toxicity Assessment on Tribal Lands in the Southwest (METALS) Superfund Research Program
    Role: Principal Investigator
    U01CA260526     (NEMBHARD, WENDY N)Sep 30, 2020 - Feb 28, 2025
    NIH
    DISCOVAR:Disparities in Immune Response to SARS-CoV-2 in ARkansas
    Role: Co-Investigator
    UH3OD023344     (DU, RUOFEI)Sep 1, 2020 - Aug 31, 2023
    NIH/Office of the Director - Pass Through: University of New Mexico
    Understanding Risk Gradients from Environment on Native American Child Health Trajectories: Toxicants, Immunomodulation, Metabolic syndromes, & Metals Exposure
    Role: Principal Investigator
    COVID-19 Testing for Arkansas     (JAMES, LAURA P)Jun 23, 2020 - May 31, 2022
    State of Arkansas
    Arkansas CASS: Arkansas Coronavirus Antibodies Seroprevalence Survey
    Role: Faculty
    P50ES026102     (LEWIS, JOHNNYE L)Aug 1, 2015 - Jul 15, 2020
    NIH, EPA
    Center for Native American Environmental Health Equity Research
    Role: Other Key Personnel
    ADH7356209     (ESWARAN, HARI)Jul 1, 2006 - Jun 30, 2021
    Arkansas Department of Health and Human Services
    Evaluation of the ANGELS High Risk Pregnancy Program
    Role: Faculty

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Ghahremani T, Britt AB, Ray E, Jones A, Du R, Magann EF. Perinatal Outcomes and Management of Umbilical Vein Varix: A Comprehensive Review of 392 Cases. J Clin Med. 2025 Jan 11; 14(2). PMID: 39860448.
      View in: PubMed
    2. Clawson AH, Jones DM, Jin J, Du R, Bullock S, Donald K, Orloff M, Miller W, Cooper S, Fagan P. Caregiver restrictions on child access to tobacco in the home and home Smoking/Vaping bans among Black/African American women caregivers who smoke and live in Resource-limited, rural areas. Prev Med Rep. 2024 Dec; 48:102918. PMID: 39534461.
      View in: PubMed
    3. Luo Q, Lu M, Butt H, Lytal N, Du R, Jiang H, An L. TimeNorm: a novel normalization method for time course microbiome data. Front Genet. 2024; 15:1417533. PMID: 39381141.
      View in: PubMed
    4. Bhandari SK, Wiest N, Sallmyr A, Du R, Tomkinson AE. Redundant but essential functions of PARP1 and PARP2 in DNA ligase I-independent DNA replication. Nucleic Acids Res. 2024 Sep 23; 52(17):10341-10354. PMID: 39106163.
      View in: PubMed
    5. Soule EK, Jones DM, Lovelady N, Thomas L, Du R, Prewitt TE, Taylor E, Baker S, Guy MC, Cornell CE, Fagan P. Using Concept Mapping to Identify Community Partners' and Researchers' Perceptions of Social Justice: A Path Toward Eliminating Chronic Disease Disparities. Health Equity. 2024; 8(1):426-436. PMID: 39011082.
      View in: PubMed
    6. Du R, Ali MM, Sung YS, Pandit AA, Payakachat N, Ounpraseuth ST, Magann EF, Eswaran H. Maternal comorbidity index and severe maternal morbidity among medicaid covered pregnant women in a US Southern rural state. J Matern Fetal Neonatal Med. 2023 Dec; 36(1):2167073. PMID: 36683016.
      View in: PubMed
    7. Wheeler CM, Torrez-Martinez NE, Torres-Chavolla E, Parvu V, Andrews JC, Du R, Robertson M, Joste NE, Cuzick J. Comparing the performance of 2 human papillomavirus assays for a new use indication: a real-world evidence-based evaluation in the United States. Am J Obstet Gynecol. 2024 02; 230(2):243.e1-243.e11. PMID: 37806613.
      View in: PubMed
    8. Cuzick J, Adcock R, Kinney W, Castle PE, Robertson M, McDonald RM, Stoler MH, Du R, Wheeler CM. Impact of HPV testing in opportunistic cervical screening: Support for primary HPV screening in the United States. Int J Cancer. 2023 07 01; 153(1):83-93. PMID: 36946690.
      View in: PubMed
    9. Bhandari SK, Wiest N, Sallmyr A, Du R, Ferry L, Defossez PA, Tomkinson AE. Unchanged PCNA and DNMT1 dynamics during replication in DNA ligase I-deficient cells but abnormal chromatin levels of non-replicative histone H1. Sci Rep. 2023 03 16; 13(1):4363. PMID: 36928068.
      View in: PubMed
    10. Lauer RC, Barry M, Smith TL, Thomas AM, Wu J, Du R, Lee JH, Rao A, Dobroff AS, Arap MA, Nunes DN, Silva IT, Dias-Neto E, Chen I, McCance DJ, Cavenee WK, Pasqualini R, Arap W. Dysregulation of the PRUNE2/PCA3 genetic axis in human prostate cancer: from experimental discovery to validation in two independent patient cohorts. Elife. 2023 01 16; 12. PMID: 36645410.
      View in: PubMed
    11. Allen JL, Du R, Powell T, Hobbs KL, Amick BC. Characterizing Cancer and Work Disparities Using Electronic Health Records. Int J Environ Res Public Health. 2022 11 29; 19(23). PMID: 36497959.
      View in: PubMed
    12. Nozadi SS, Aguiar A, Du R, Enright EA, Schantz SL, Miller C, Rennie B, Quetawki M, MacKenzie D, Lewis JL. Cross-cultural applicability of eye-tracking in assessing attention to emotional faces in preschool-aged children. Emotion. 2023 Aug; 23(5):1385-1399. PMID: 36107657.
      View in: PubMed
    13. Boehme KW, Kennedy JL, Snowden J, Owens SM, Kouassi M, Mann RL, Paredes A, Putt C, James L, Jin J, Du R, Kirkpatrick C, Modi Z, Caid K, Young S, Zohoori N, Kothari A, Boyanton BL, Craig Forrest J. Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic. J Pediatric Infect Dis Soc. 2022 Jun 22; 11(6):248-256. PMID: 35294550.
      View in: PubMed
    14. Figueiredo JC, Hirsch FR, Kushi LH, Nembhard WN, Crawford JM, Mantis N, Finster L, Merin NM, Merchant A, Reckamp KL, Melmed GY, Braun J, McGovern D, Parekh S, Corley DA, Zohoori N, Amick BC, Du R, Gregersen PK, Diamond B, Taioli E, Sariol C, Espino A, Weiskopf D, Gifoni A, Brien J, Hanege W, Lipsitch M, Zidar DA, Scheck McAlearney A, Wajnberg A, LaBaer J, Yvonne Lewis E, Binder RA, Moormann AM, Forconi C, Forrester S, Batista J, Schieffelin J, Kim D, Biancon G, VanOudenhove J, Halene S, Fan R, Barouch DH, Alter G, Pinninti S, Boppana SB, Pati SK, Latting M, Karaba AH, Roback J, Sekaly R, Neish A, Brincks AM, Granger DA, Karger AB, Thyagarajan B, Thomas SN, Klein SL, Cox AL, Lucas T, Furr-Holden D, Key K, Jones N, Wrammerr J, Suthar M, Yu Wong S, Bowman NM, Simon V, Richardson LD, McBride R, Krammer F, Rana M, Kennedy J, Boehme K, Forrest C, Granger SW, Heaney CD, Knight Lapinski M, Wallet S, Baric RS, Schifanella L, Lopez M, Fern?ndez S, Kenah E, Panchal AR, Britt WJ, Sanz I, Dhodapkar M, Ahmed R, Bartelt LA, Markmann AJ, Lin JT, Hagan RS, Wolfgang MC, Skarbinski J. Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies. Open Forum Infect Dis. 2022 Jun; 9(6):ofac171. PMID: 35765315.
      View in: PubMed
    15. Cardenas VM, Kennedy JL, Williams M, Nembhard WN, Zohoori N, Du R, Jin J, Boothe D, Fischbach LA, Kirkpatrick C, Modi Z, Caid K, Owens S, Forrest JC, James L, Boehme KW, Olgaard E, Gardner SF, Amick BC. State-wide random seroprevalence survey of SARS-CoV-2 past infection in a southern US State, 2020. PLoS One. 2022; 17(4):e0267322. PMID: 35476717.
      View in: PubMed
    16. Kennedy JL, Forrest JC, Young SG, Amick B, Williams M, James L, Snowden J, Cardenas VM, Boothe D, Kirkpatrick C, Modi Z, Caid K, Owens S, Kouassi M, Mann R, Putt C, Irish-Clardy K, Macechko M, Brimberry RK, Nembhard WN, McElfish PA, Du R, Jin J, Zohoori N, Kothari A, Hagrass H, Olgaard E, Boehme KW. Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas. Open Forum Infect Dis. 2022 May; 9(5):ofac154. PMID: 35493126.
      View in: PubMed
    17. Du R, Luo L, Hudson LG, Nozadi S, Lewis J. An adjusted partial least squares regression framework to utilize additional exposure information in environmental mixture data analysis. J Appl Stat. 2023; 50(8):1790-1811. PMID: 37260474.
      View in: PubMed
    18. Du R, Choi YJ, Lee JH, Songthip O, Hu Z. A weighted Jackknife approach utilizing linear model based-estimators for clustered data. Commun Stat Simul Comput. 2024; 53(2):1048-1067. PMID: 38523866.
      View in: PubMed
    19. Nozadi SS, Li L, Luo L, MacKenzie D, Erdei E, Du R, Roman CW, Hoover J, O'Donald E, Burnette C, Lewis J. Prenatal Metal Exposures and Infants' Developmental Outcomes in a Navajo Population. Int J Environ Res Public Health. 2021 12 31; 19(1). PMID: 35010683.
      View in: PubMed
    20. Corken A, Ghosh SP, Du R, Boerma M, Ware J, Pathak R. Platelet glycoprotein Iba provides radiation protection. Radiother Oncol. 2022 02; 167:143-148. PMID: 34971661.
      View in: PubMed
    21. Cuzick J, Du R, Adcock R, Kinney W, Joste N, McDonald RM, English K, Torres SM, Saslow D, Wheeler CM. Uptake of co-testing with HPV and cytology for cervical screening: a population-based evaluation in the United States. Gynecologic Oncology. 2021; 162(3):555-559.
      View Publication
    22. Cuzick J, Du R, Adcock R, Kinney W, Joste N, McDonald RM, English K, Torres SM, Saslow D, Wheeler CM. Uptake of co-testing with HPV and cytology for cervical screening: A population-based evaluation in the United States. Gynecol Oncol. 2021 09; 162(3):555-559. PMID: 34253387.
      View in: PubMed
    23. Harris M, Mendiratta P, Azhar G, Du R, Jin J. . The PBAR Protocol: Antipsychotic Medication Reduction in the Nursing Home. OBM Geriatrics. 2021; 2(5).
    24. Blair CK, Harding E, Wiggins C, Kang H, Schwartz M, Tarnower A, Du R, Kinney AY. A Home-Based Mobile Health Intervention to Replace Sedentary Time With Light Physical Activity in Older Cancer Survivors: Randomized Controlled Pilot Trial. JMIR Cancer. 2021 Apr 13; 7(2):e18819. PMID: 33847588.
      View in: PubMed
    25. Manda-Mapalo MT, Fine SG, Safadi S, Lee JH, Du R, Sussman AL, Mishra S, Selwyn RG, Saline JL, Hine WL, Brown-Glaberman UA. Breast Cancer Screening Among Medically Underserved Women in New Mexico: Potential for Lower Recall Rates with Digital Breast Tomosynthesis. J Womens Health (Larchmt). 2020 12; 29(12):1596-1601. PMID: 32991242.
      View in: PubMed
    26. De La Rosa VY, Hoover J, Du R, Jimenez EY, MacKenzie D, Lewis J. Diet quality among pregnant women in the Navajo Birth Cohort Study. Matern Child Nutr. 2020 07; 16(3):e12961. PMID: 32026554.
      View in: PubMed
    27. Zhang Y, Xia H, Wang Y, Chen L, Li S, Hussein IA, Wu Y, Shang Y, Yao S, Du R. The rate of missed diagnosis of lower-limb DVT by ultrasound amounts to 50% or so in patients without symptoms of DVT: A meta-analysis. Medicine. 2019; 37(98):e17103.
    28. Nozadi SS, Li L, Clifford J, Du R, Murphy K, Chen L, Seanez P, Burnette C, MacKenzie D, Lewis JL. Use of Ages and Stages Questionnaires? (ASQ) in a Navajo population: Comparison with the U.S. normative dataset. Child Care Health Dev. 2019 09; 45(5):709-718. PMID: 31276599.
      View in: PubMed
    29. Du, R, Lee JH. A weighted Jackknife method for clustered data. Communications in Statistics-Theory and Methods. 2019; 8(48):1963-1980.
    30. Du R, An L, Fang Z. Performance evaluation of normalization approaches for metagenomic compositional data on differential abundance analysis. New Frontiers of Biostatistics and Bioinformatics. 2018; 329-344.
    31. Chen Y, Hou Y, Yang J, Du R, Chen C, Chen F, Wang H, Ge R, Chen J. P75 Involved in the Ubiquitination of a-synuclein in Rotenone-based Parkinson's Disease Models. Neuroscience. 2018 09 15; 388:367-373. PMID: 30081046.
      View in: PubMed
    32. Dashner-Titus EJ, Hoover J, Li L, Lee JH, Du R, Liu KJ, Traber MG, Ho E, Lewis J, Hudson LG. Metal exposure and oxidative stress markers in pregnant Navajo Birth Cohort Study participants. Free Radic Biol Med. 2018 08 20; 124:484-492. PMID: 29723666.
      View in: PubMed
    33. Du R, Fang Z. Statistical correction for functional metagenomic profiling of a microbial community with short NGS reads. J Appl Stat. 2018; 45(14):2521-2535. PMID: 30505061.
      View in: PubMed
    34. Floruta CM, Du R, Kang H, Stein JL, Weick JP. Default Patterning Produces Pan-cortical Glutamatergic and CGE/LGE-like GABAergic Neurons from Human Pluripotent Stem Cells. Stem Cell Reports. 2017 11 14; 9(5):1463-1476. PMID: 29107596.
      View in: PubMed
    35. Steffen LE, Du R, Gammon A, Mandelblatt JS, Kohlmann WK, Lee JH, Buys SS, Stroup AM, Campo RA, Flores KG, Vicu?a B, Schwartz MD, Kinney AY. Genetic Testing in a Population-Based Sample of Breast and Ovarian Cancer Survivors from the REACH Randomized Trial: Cost Barriers and Moderators of Counseling Mode. Cancer Epidemiol Biomarkers Prev. 2017 12; 26(12):1772-1780. PMID: 28971986.
      View in: PubMed
    36. Patt YZ, Murad W, Fekrazad MH, Baron AD, Bansal P, Boumber Y, Steinberg K, Lee SJ, Bedrick E, Du R, Lee FC. INST OX-05-024: first line gemcitabine, oxaliplatin, and erlotinib for primary hepatocellular carcinoma and bile duct cancers: a multicenter Phase II trial. Cancer Med. 2017 Sep; 6(9):2042-2051. PMID: 28801995.
      View in: PubMed
    37. Benard VB, Castle PE, Jenison SA, Hunt WC, Kim JJ, Cuzick J, Lee JH, Du R, Robertson M, Norville S, Wheeler CM. Population-Based Incidence Rates of Cervical Intraepithelial Neoplasia in the Human Papillomavirus Vaccine Era. JAMA Oncol. 2017 Jun 01; 3(6):833-837. PMID: 27685805.
      View in: PubMed
    38. Kinney AY, Steffen LE, Brumbach BH, Kohlmann W, Du R, Lee JH, Gammon A, Butler K, Buys SS, Stroup AM, Campo RA, Flores KG, Mandelblatt JS, Schwartz MD. Randomized Noninferiority Trial of Telephone Delivery of BRCA1/2 Genetic Counseling Compared With In-Person Counseling: 1-Year Follow-Up. J Clin Oncol. 2016 08 20; 34(24):2914-24. PMID: 27325848.
      View in: PubMed
    39. Sohn MB, Du R, An L. A robust approach for identifying differentially abundant features in metagenomic samples. Bioinformatics. 2015 Jul 15; 31(14):2269-75. PMID: 25792553.
      View in: PubMed
    40. Du R, Mercante D, An L, Fang Z. A Statistical Approach to Correcting Cross-Annotations in a Metagenomic Functional Profile Generated by Short Reads. J Biom Biostat. 2014; 5(4). PMID: 29710879.
      View in: PubMed
    41. Pookhao N, Sohn MB, Li Q, Jenkins I, Du R, Jiang H, An L. A two-stage statistical procedure for feature selection and comparison in functional analysis of metagenomes. Bioinformatics. 2015 Jan 15; 31(2):158-65. PMID: 25256572.
      View in: PubMed
    42. Du R, Fang Z. Analysis of Metagenomic Data. Statistical Analysis of Next Generation Sequencing Data. 2014; 335-353.
    43. Du R, Mercante D, Fang Z. An artificial functional family filter in homolog searching in next-generation sequencing metagenomics. PLoS One. 2013; 8(3):e58669. PMID: 23516532.
      View in: PubMed
    44. Fang Z, Du R, Edwards A, Flemington EK, Zhang K. The sequence structures of human microRNA molecules and their implications. PLoS One. 2013; 8(1):e54215. PMID: 23349828.
      View in: PubMed
    45. Fang Z, Du R, Cui X. Uniform approximation is more appropriate for Wilcoxon Rank-Sum Test in gene set analysis. PLoS One. 2012; 7(2):e31505. PMID: 22347488.
      View in: PubMed
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