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Joseph Holthoff

TitleFellow Physician
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentCollege of Medicine Administration
DivisionFaculty & Student Affairs
AddressB2-129-2 Biomedical Research I
4301 W.Markham
Mail Slot # 634
Little Rock AR 72205
Phone501-686-5162
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    F30DK085705     (HOLTHOFF, JOSEPH HUNTER)Apr 1, 2010 - Dec 31, 2014
    NIH/NIDDK
    Preclinical evaluation of resveratrol in sepsis-induced renal injury
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Holthoff JH, Wang Z, Patil NK, Gokden N, Mayeux PR. Rolipram improves renal perfusion and function during sepsis in the mouse. J Pharmacol Exp Ther. 2013 Nov; 347(2):357-64. PMID: 24018639.
      View in: PubMed
    2. Wang Z, Holthoff JH, Seely KA, Pathak E, Spencer HJ, Gokden N, Mayeux PR. Development of oxidative stress in the peritubular capillary microenvironment mediates sepsis-induced renal microcirculatory failure and acute kidney injury. Am J Pathol. 2012 Feb; 180(2):505-16. PMID: 22119717.
      View in: PubMed
    3. Holthoff JH, Wang Z, Seely KA, Gokden N, Mayeux PR. Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury. Kidney Int. 2012 Feb; 81(4):370-8. PMID: 21975863.
      View in: PubMed
    4. Myers CN, Berner GB, Holthoff JH, Martinez-Fonts K, Harper JA, Alford S, Taylor MN, Duina AA. Mutant versions of the S. cerevisiae transcription elongation factor Spt16 define regions of Spt16 that functionally interact with histone H3. PLoS One. 2011; 6(6):e20847. PMID: 21673966.
      View in: PubMed
    5. Seely KA, Holthoff JH, Burns ST, Wang Z, Thakali KM, Gokden N, Rhee SW, Mayeux PR. Hemodynamic changes in the kidney in a pediatric rat model of sepsis-induced acute kidney injury. Am J Physiol Renal Physiol. 2011 Jul; 301(1):F209-17. PMID: 21511700.
      View in: PubMed
    6. Holthoff JH, Woodling KA, Doerge DR, Burns ST, Hinson JA, Mayeux PR. Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite. Biochem Pharmacol. 2010 Oct 15; 80(8):1260-5. PMID: 20599800.
      View in: PubMed
    7. Wu L, Tiwari MM, Messer KJ, Holthoff JH, Gokden N, Brock RW, Mayeux PR. Peritubular capillary dysfunction and renal tubular epithelial cell stress following lipopolysaccharide administration in mice. Am J Physiol Renal Physiol. 2007 Jan; 292(1):F261-8. PMID: 16926442.
      View in: PubMed
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