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Paul Drew

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentNeurobiology & Developmental Science, College of Medicine
DivisionNeuro & Devel SImmune
Address563-2 Biomedical Research II
200 South Cedar
Mail Slot # 846
Little Rock AR 72202
Phone501-296-1265
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    Other Positions
    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentNeurology, College of Medicine


    Collapse Overview 
    Collapse overview
    Drew Lab Research:
    Multiple Sclerosis
    Fetal Alcohol Spectrum Disorders
    Neuroimmunology
    Innate and Adaptive Immunity


    Collapse Affiliation 
    Collapse member of
    American Association of Immunologists
    American Association for the Advancement of Science
    American Society of Neurochemistry
    Fetal Alcohol Spectrum Disorders Study Group
    International Cytokine Society
    International Society of Neuroimmunology
    Research Society on Alcoholism
    Society for Neuroscience

    Collapse Research Funds 
    Collapse research activities
    R01AA026665     (DREW, PAUL D)Sep 1, 2018 - Aug 31, 2023
    NIH
    Neuroinflammation: Role in FASD Cognitive Deficits
    Role: Principal Investigator

    R01AA027111     (DREW, PAUL D)Sep 1, 2018 - Jun 30, 2023
    NIH
    Dynamic neuroimmune interactions in the onset and progression of FASD
    Role: Co-Investigator

    R01AA024695     (DREW, PAUL D)Aug 1, 2016 - Jul 31, 2021
    NIH
    Regulation of Neuroimmune Responses in FASD Models
    Role: Co-Principal Investigator

    R21AA023723     (KANE, CYNTHIA J)Mar 10, 2015 - Feb 28, 2018
    NIH
    Neuroinflammatory Mechanisms in FASD: Development of Novel Therapeutic Strategies
    Role: Co-Investigator

    R01AA018834     (KANE, CYNTHIA J)Sep 30, 2009 - Aug 31, 2016
    NIH
    Microglia modulate ethanol impact on CNS development.
    Role: Co-Investigator

    R21AA018839     (DREW, PAUL D)Sep 30, 2009 - May 31, 2013
    NIH
    Effects of Alcohol on Microglia and Innate Immunity
    Role: Principal Investigator

    RC1AA019108     (DREW, PAUL D)Sep 25, 2009 - May 31, 2013
    NIH
    Mechanisms of Ethanol-Induced Neuroinflammation and Neurodegeneration
    Role: Principal Investigator

    RG 3893A2/1     (DREW, PAUL)Apr 1, 2007 - Mar 31, 2011
    National Multiple Sclerosis Society
    LXR agonists as treatment for autoimmune demyelination
    Role: Principal Investigator

    RG 389A2/1     (DREW, PAUL)Apr 1, 2007 - Mar 31, 2010
    National Multiple Sclerosis Society
    LXR agonists as treatment for autoimmune demyelination
    Role: Principal Investigator

    RG3427B10/1T     (DREW, PAUL)Apr 1, 2007 - Mar 31, 2010
    National Multiple Sclerosis Society - Pass Through: The Ohio State University Research Foundation
    PPAR-alpha agonists as treatment for autoimmune demyelination
    Role: Principal Investigator

    RG 3427B10/IT     (DREW, PAUL)Apr 1, 2007 - Mar 31, 2008
    National Multiple Sclerosis Society - Pass Through: The Ohio State University Research Foundation
    PPAR-alpha agonists as treatment for autoimmune demyelination
    Role: Principal Investigator

    P30NS047546     (DREW, PAUL D)Aug 15, 2004 - Jul 31, 2010
    NIH
    Neuroscience Research Center Core Facility at UAMS
    Role: Principal Investigator

    R01AA014645     (KANE, CYNTHIA J.M.)Jul 1, 2004 - Jun 30, 2010
    NIH
    CNS Development &Alcohol: Microglia-Neuron Interactions
    Role: Co-Investigator

    R21AA014888     (KANE, CYNTHIA J.M.)May 1, 2004 - Apr 30, 2007
    NIH
    Alcohol Pathogenesis in CNS Microglial Cells
    Role: Co-Investigator

    RG 3427-A-8     (DREW, PAUL)Apr 1, 2003 - Mar 31, 2006
    National Multiple Sclerosis Society - Pass Through: University of Texas - Southwestern
    PPAR-Agonist as Treatment for Autoimmune Demyelination (Subcontract from UT Southwestern Medical Center)
    Role: Principal Investigator

    RG-3427-A-8     (DREW, PAUL)Apr 1, 2003 - Mar 31, 2006
    National Multiple Sclerosis Society - Pass Through: University of Texas - Southwestern
    PPAR-Agonist as Treatment for Autoimmune Demyelination (Subcontract from UT Southwestern Medical Center)
    Role: Principal Investigator

    R01NS042860     (DREW, PAUL D)Dec 15, 2002 - Nov 30, 2008
    NIH
    PPAR-gamma Immune Regulation and Multiple Sclerosis
    Role: Principal Investigator

    RG 3198A1/1     (DREW, PAUL)Apr 1, 2001 - Sep 30, 2004
    National Multiple Sclerosis Society
    Female Sex Steroids: Effects on Glia
    Role: Principal Investigator

    P01AG012411     (GRIFFIN, SUE TILTON)Jun 1, 1995 - May 31, 2021
    NIH
    Early Events in Alzheimer Pathogenesis
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Lowery RL, Cealie MY, Lamantia CE, Mendes MS, Drew PD, Majewska AK. Microglia and astrocytes show limited, acute alterations in morphology and protein expression following a single developmental alcohol exposure. J Neurosci Res. 2021 Feb 19. PMID: 33606320.
      View in: PubMed
    2. Kane CJM, Douglas JC, Rafferty T, Johnson JW, Niedzwiedz-Massey VM, Phelan KD, Majewska AK, Drew PD. Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders. J Neurosci Res. 2021 Feb 02. PMID: 33533128.
      View in: PubMed
    3. Kane CJM, Drew PD. Neuroinflammatory contribution of microglia and astrocytes in fetal alcohol spectrum disorders. J Neurosci Res. 2020 Sep 22. PMID: 32959429.
      View in: PubMed
    4. Chen J, Martindale JL, Cramer C, Gorospe M, Atasoy U, Drew PD, Yu S. The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells. J Biol Chem. 2017 09 01; 292(35):14532-14543. PMID: 28684423.
      View in: PubMed
    5. Cippitelli A, Domi E, Ubaldi M, Douglas JC, Li HW, Demopulos G, Gaitanaris G, Roberto M, Drew PD, Kane CJM, Ciccocioppo R. Protection against alcohol-induced neuronal and cognitive damage by the PPAR? receptor agonist pioglitazone. Brain Behav Immun. 2017 Aug; 64:320-329. PMID: 28167117.
      View in: PubMed
    6. Drew PD, Kane CJ. Peroxisome Proliferator-Activated Receptor-? Agonists: Potential Therapeutics for Neuropathology Associated with Fetal Alcohol Spectrum Disorders. J Clin Cell Immunol. 2016 Dec; 7(6). PMID: 28203487.
      View in: PubMed
    7. Kane CJ, Drew PD. Inflammatory responses to alcohol in the CNS: nuclear receptors as potential therapeutics for alcohol-induced neuropathologies. J Leukoc Biol. 2016 11; 100(5):951-959. PMID: 27462100.
      View in: PubMed
    8. Odle AK, Drew PD, Childs GV. Giant mice reveal new roles for GH in regulating the adipose immune microenvironment. Endocrinology. 2015 May; 156(5):1613-5. PMID: 25886070.
      View in: PubMed
    9. Drew PD, Johnson JW, Douglas JC, Phelan KD, Kane CJ. Pioglitazone blocks ethanol induction of microglial activation and immune responses in the hippocampus, cerebellum, and cerebral cortex in a mouse model of fetal alcohol spectrum disorders. Alcohol Clin Exp Res. 2015 Mar; 39(3):445-54. PMID: 25703036.
      View in: PubMed
    10. Xie L, Chen J, McMickle A, Awar N, Nady S, Sredni B, Drew PD, Yu S. The immunomodulator AS101 suppresses production of inflammatory cytokines and ameliorates the pathogenesis of experimental autoimmune encephalomyelitis. J Neuroimmunol. 2014 Aug 15; 273(1-2):31-41. PMID: 24975323.
      View in: PubMed
    11. Drew PD, Kane CJ. Fetal alcohol spectrum disorders and neuroimmune changes. Int Rev Neurobiol. 2014; 118:41-80. PMID: 25175861.
      View in: PubMed
    12. Kane CJ, Phelan KD, Douglas JC, Wagoner G, Johnson JW, Xu J, Phelan PS, Drew PD. Effects of ethanol on immune response in the brain: region-specific changes in adolescent versus adult mice. Alcohol Clin Exp Res. 2014 Feb; 38(2):384-91. PMID: 24033454.
      View in: PubMed
    13. Kane CJ, Phelan KD, Douglas JC, Wagoner G, Johnson JW, Xu J, Drew PD. Effects of ethanol on immune response in the brain: region-specific changes in aged mice. J Neuroinflammation. 2013 May 23; 10:66. PMID: 23701841.
      View in: PubMed
    14. Xu J, Wagoner G, Douglas JC, Drew PD. Beta-Lapachone ameliorization of experimental autoimmune encephalomyelitis. J Neuroimmunol. 2013; 254(1-2):46 - 54.
    15. Kane, C.J.M., K.D. Phelan, P.D. Drew. Encyclopedia of Addictive Behaviors. Molecular Targets of Ethanol in the Developing Brain. 2013; 147.
    16. Drew PD. Peroxisome-Proliferator-activated receptor-gamma Agonists Protect Neurons and Microglia From Ethanol in the Developing Cerebellum. Society of Leukocyte Biology Annual Meeting. 2012.
    17. Xu J, Wagoner G, Douglas JC, Drew PD. ß-Lapachone ameliorization of experimental autoimmune encephalomyelitis. J Neuroimmunol. 2013 Jan 15; 254(1-2):46-54. PMID: 23010281.
      View in: PubMed
    18. Kane CJ, Phelan KD, Drew PD. Neuroimmune mechanisms in fetal alcohol spectrum disorder. Dev Neurobiol. 2012 Oct; 72(10):1302-16. PMID: 22623427.
      View in: PubMed
    19. Wight RD, Tull CA, Deel MW, Stroope BL, Eubanks AG, Chavis JA, Drew PD, Hensley LL. Resveratrol effects on astrocyte function: relevance to neurodegenerative diseases. Biochem Biophys Res Commun. 2012 Sep 14; 426(1):112-5. PMID: 22917537.
      View in: PubMed
    20. Burns SA, Lee Archer R, Chavis JA, Tull CA, Hensley LL, Drew PD. Mitoxantrone repression of astrocyte activation: relevance to multiple sclerosis. Brain Res. 2012 Sep 14; 1473:236-41. PMID: 22884503.
      View in: PubMed
    21. Drew PD. Protection of Neurons and Microglia Against Ethanol in the Developing Cerebellum. 2012.
    22. Drew. P.D, K.D. Phelan, C.J. M. Kane. Protection of neurons and microglia against ethanol in the developing cerebellum. Alcohol Clin & Exper. Res. 2012; 325A.
    23. Drew PD. Nuclear Receptors as Modulators of Multiple Sclerosis. Rampy Foundation for MS Research. 2012.
    24. Drew, P.D, K.D. Phelan, J.C. Douglas, C.J.M. Kane. Peroxisome proliferator-activated receptor-gamma agonists protect neurons and microglia from ethanol in the developing cerebellum. Society of Leukocyte Biology Annual Meeting Publication. 2012.
    25. Drew PD, C.J.M. Kane. Neural-Immune Interactions in Brain Function and Alcohol Related Disorders. Neuroimmune Mechanisms in Glia and their Interplay with Alcohol Exposure across the Lifespan. 2012.
    26. Kane, C.J.M, K.D. Phelan, J.C. Douglas, G. Wagoner, J.Johnson, J. Xu, J.A. Chavis, P.S. Phelan, P.D. Drew. Alcohol regulates expression of glial-derived neuroimmune factors in an age-dependant manner. Alcohol Clin & Exper. Res. 36(6):91A. 2012.
    27. Drew PD. Nuclear Receptors as Modulators of Multiple Sclerosis. Arkansas State University. 2011.
    28. Solt LA, Kumar N, Nuhant P, Wang Y, Lauer JL, Liu J, Istrate MA, Kamenecka TM, Roush WR, Vidovic D, Schürer SC, Xu J, Wagoner G, Drew PD, Griffin PR, Burris TP. Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand. Nature. 2011 Apr 28; 472(7344):491-4. PMID: 21499262.
      View in: PubMed
    29. Drew PD. Role of Neuroimmune Signaling Molecules in the Neuropathology of Fetal Alcohol Spectrum Disorders. Society of Neuroimmune Pharmacology Annual Meeting. 2011.
    30. Kane CJ, Phelan KD, Han L, Smith RR, Xie J, Douglas JC, Drew PD. Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-? agonists. Brain Behav Immun. 2011 Jun; 25 Suppl 1:S137-45. PMID: 21376806.
      View in: PubMed
    31. Solt, L.A., N. Kumar, P. Nuhant, Y. Wang, J.L. Lauer, J. Liu, M.A. Istrate, T.M. Kamenecka, W.R. Roush, D. Vidovic, S.C. Schurer, J.Xu, G. Wagoner, P.D. Drew, P.R. Griffin, T. P. Burris. Inhibition of T(H)17 differentiation and asuppression of autoimmunity by a selective ROR ligand. Nature. 2011; 472:491-494.
    32. Kane, C.J.M, K.D. Phelan, J.C. Douglas, G. Wagoner, J. Johnson, J. Xu, P.D. Drew. Alcohol exposure activates the neuroimmune system in rodent models. Neuroscience Meeting Planner. Program No. 749.09. 2011.
    33. Kane, C.J.M, J.C. Douglas, J. Xu, J. Johnson, G. Wagoner, D. Rose, K.D. Phelan, And P.D. Drew. Brain region- and age-specific impact of ethanol on glial derived neuroimflammatory molecules. Alcohol clin & exper. Res. 35(6):49A. 2011.
    34. Kane, C.J.M., K.D. Phelan, L. Han, R.R. Smith, J. Xie, J.C. Douglas, P.D. Drew. Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator activated receptor gamma ligands. Brain Behavior and Immunity. 2011; (25):S137-S145.
    35. Drew PD. Peroxisome Proliferator-Activated Receptors and Liver X Receptors As Modulators of Multiple Sclerosis. National Multiple Sclerosis Society- South Central Region Program. 2010.
    36. Drew PD. Role of Glial Toll-Like Receptor Signaling in Ethanol Induced Neurodegeneration. Fetal Alcohol Spectrum Disorders Study Group Annual Meeting. 2010.
    37. Drew PD. Current Research and Therapies for Multiple Sclerosis. MS Support Group. 2010.
    38. Xu, J., C.X. Zhang-Ghandi, P.D. Drew. Suppression IL-23 and TLR signaling by liver X receptor agonist TO901317 may contribute to its therapeutic effects in EAE. 2010.
    39. Drew PD. Peroxisome Proliferator-Activated Receptors and Liver X Receptors As Modulators of Multiple Sclerosis. University of Nebraska Medical Center. 2010.
    40. Xu. J., P.D. Drew. B-lapachone suppresssion of imflammatory cytokines IL-23 and IL-17: relevance to multiple sclerosis. 2010.
    41. Xu J, Wagoner G, Douglas JC, Drew PD. Liver X receptor agonist regulation of Th17 lymphocyte function in autoimmunity. J Leukoc Biol. 2009 Aug; 86(2):401-9. PMID: 19406833.
      View in: PubMed
    42. Gocke AR, Hussain RZ, Yang Y, Peng H, Weiner J, Ben LH, Drew PD, Stuve O, Lovett-Racke AE, Racke MK. Transcriptional modulation of the immune response by peroxisome proliferator-activated receptor-{alpha} agonists in autoimmune disease. J Immunol. 2009 Apr 01; 182(7):4479-87. PMID: 19299749.
      View in: PubMed
    43. Drew PD. Peroxisome Proliferator-Activated Receptors: Potential Modulators of Multiple Sclerosis. UAMS, Department of Microbiology and Immunology. 2009.
    44. Racke MK, Drew PD. Toll-like receptors in multiple sclerosis. Curr Top Microbiol Immunol. 2009; 336:155-68. PMID: 19688333.
      View in: PubMed
    45. Drew PD. Peroxisome Proliferator-Activated Receptors: Potential Modulators of Multiple Sclerosis. Medical University of South Carolina. 2009.
    46. Racke, MK, Drew PD. Toll-like Receptors: Roles in Infection and Neuropathology. Toll-like Receptors (TLRs) in Multiple Sclerosis. 2009; 8.
    47. Kielian T, Syed MM, Liu S, Phulwani NK, Phillips N, Wagoner G, Drew PD, Esen N. The synthetic peroxisome proliferator-activated receptor-gamma agonist ciglitazone attenuates neuroinflammation and accelerates encapsulation in bacterial brain abscesses. J Immunol. 2008 Apr 01; 180(7):5004-16. PMID: 18354226.
      View in: PubMed
    48. Xu J, Barger SW, Drew PD. The PPAR-gamma Agonist 15-Deoxy-Delta-Prostaglandin J(2) Attenuates Microglial Production of IL-12 Family Cytokines: Potential Relevance to Alzheimer's Disease. PPAR Res. 2008; 2008:349185. PMID: 18615183.
      View in: PubMed
    49. Drew PD, Xu J, Racke MK. PPAR-gamma: Therapeutic Potential for Multiple Sclerosis. PPAR Res. 2008; 2008:627463. PMID: 18604287.
      View in: PubMed
    50. Racke MK, Drew PD. PPARs in Neuroinflammation. PPAR Res. 2008; 2008:638356. PMID: 18682822.
      View in: PubMed
    51. Yang Y, Gocke AR, Lovett-Racke A, Drew PD, Racke MK. PPAR Alpha Regulation of the Immune Response and Autoimmune Encephalomyelitis. PPAR Res. 2008; 2008:546753. PMID: 18645614.
      View in: PubMed
    52. Esen, N., S. Liu, M.M. Syed, N. Phillips, G. Wagoner, P.D. Drew, And T. Kielian. The synthetic PPAR-gamma agonist ciglitazone attenuates Neuroinflammation and accelerates encapsulation in bacterial brain abcesses. J. Neurochemistry. 2008; 107.
    53. Xu, J., M.K. Racke, And P.D. Drew. Regulation of CNS inflammation by peroxisome proliferator-activated receptor-alpha agonist fenofibrate. J. Neurochemistry. 2008; 107.
    54. Xu J, Barger SW, Drew PD. The PPAR-{gamma} agonist 15-deoxy-{delta}12,14- prostaglandin J2 (15d-PGJ2) attenuates microglial production of IL-12 family cytokines: Potential relevance to Alzheimer’s disease. PPAR Research. 2008; :349185.
    55. Xu, J, P.D. Drew. Liver X receptor aganist T0901317 ameliorates experimental autoimmune encephalomyelitis through supressing IL-17 production. J. Neuroimmunol. 2008; 203:241.
    56. Xu J, Racke MK, Drew PD. Peroxisome proliferator-activated receptor-alpha agonist fenofibrate regulates IL-12 family cytokine expression in the CNS: relevance to multiple sclerosis. J Neurochem. 2007 Dec; 103(5):1801-10. PMID: 17727629.
      View in: PubMed
    57. Xu J, Drew PD. Peroxisome proliferator-activated receptor-gamma agonists suppress the production of IL-12 family cytokines by activated glia. J Immunol. 2007 Feb 01; 178(3):1904-13. PMID: 17237441.
      View in: PubMed
    58. Liebregts T, Adam B, Bredack C, Röth A, Heinzel S, Lester S, Downie-Doyle S, Smith E, Drew P, Talley NJ, Holtmann G. Immune activation in patients with irritable bowel syndrome. Gastroenterology. 2007 Mar; 132(3):913-20. PMID: 17383420.
      View in: PubMed
    59. Cull, C.T., N.S. Lemons, T.H. Sanford, R.D. Wight, J.A. Chavis, P.D. Drew, And L.L. Hensley. Mechanism of action by which ajulemic acid and resveratrol modulate microglial activation in cell model of MS. J. Neurochemistry. 2007; 228.
    60. Xu, J., M.K. Racke, And P.D. Drew. Peroxisome proliferator-activated receptor-alpha agonist fenofibrate inhibits IL-12 family cytokines by activated microglia. J. Neurochemistry. 2007; 230.
    61. Zhang-Gandhi CX, Drew PD. Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes. J Neuroimmunol. 2007 Feb; 183(1-2):50-9. PMID: 17175031.
      View in: PubMed
    62. Xu J, Chavis JA, Racke MK, Drew PD. Peroxisome proliferator-activated receptor-alpha and retinoid X receptor agonists inhibit inflammatory responses of astrocytes. J Neuroimmunol. 2006 Jul; 176(1-2):95-105. PMID: 16764943.
      View in: PubMed
    63. Drew PD, Xu J, Storer PD, Chavis JA, Racke MK. Peroxisome proliferator-activated receptor agonist regulation of glial activation: relevance to CNS inflammatory disorders. Neurochem Int. 2006 Jul; 49(2):183-9. PMID: 16753239.
      View in: PubMed
    64. Racke MK, Gocke AR, Muir M, Diab A, Drew PD, Lovett-Racke AE. Nuclear receptors and autoimmune disease: the potential of PPAR agonists to treat multiple sclerosis. J Nutr. 2006 Mar; 136(3):700-3. PMID: 16484546.
      View in: PubMed
    65. Xu, J., P.D. Storer, And P.D. Drew. PPAR-gamma agonists suppress the production of IL-12/IL-23 by activated microglia and astrocytes. J. Neurochemistry. 2006; 19.
    66. Zhang, C.X., And P.D. Drew. Effect of liver X receptor agonist on microglial cell activation: rellevance to multiple sclerosis. J. Neurochemistry. 2006; 44.
    67. Xu J, Drew PD. 9-Cis-retinoic acid suppresses inflammatory responses of microglia and astrocytes. J Neuroimmunol. 2006 Feb; 171(1-2):135-44. PMID: 16303184.
      View in: PubMed
    68. Xu J, Storer PD, Chavis JA, Racke MK, Drew PD. Agonists for the peroxisome proliferator-activated receptor-alpha and the retinoid X receptor inhibit inflammatory responses of microglia. J Neurosci Res. 2005 Aug 01; 81(3):403-11. PMID: 15968640.
      View in: PubMed
    69. Storer PD, Xu J, Chavis J, Drew PD. Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis. J Neuroimmunol. 2005 Apr; 161(1-2):113-22. PMID: 15748950.
      View in: PubMed
    70. Storer PD, Xu J, Chavis JA, Drew PD. Cyclopentenone prostaglandins PGA2 and 15-deoxy-delta12,14 PGJ2 suppress activation of murine microglia and astrocytes: implications for multiple sclerosis. J Neurosci Res. 2005 Apr 01; 80(1):66-74. PMID: 15723383.
      View in: PubMed
    71. Drew PD, Storer PD, Xu J, Chavis JA. Hormone regulation of microglial cell activation: relevance to multiple sclerosis. Brain Res Brain Res Rev. 2005 Apr; 48(2):322-7. PMID: 15850670.
      View in: PubMed
    72. Kielian T, Drew PD. Cytokines and Brain: Health and Diseases: in Inflammatory Disorders of the Nervous System: Pathogenesis, Immunology and Clinical Management. 2005.
    73. Drew PD, J. Xu, P.D. Storer, And M.K. Racke. Peroxisome proliferators-activated receptor regulation of glial activation: relevance to CNS inflammatory disorders. J. Neurochemistry. 2005; 116.
    74. Kielian T, McMahon M, Bearden ED, Baldwin AC, Drew PD, Esen N. S. aureus-dependent microglial activation is selectively attenuated by the cyclopentenone prostaglandin 15-deoxy-Delta12,14- prostaglandin J2 (15d-PGJ2). J Neurochem. 2004 Sep; 90(5):1163-72. PMID: 15312171.
      View in: PubMed
    75. Lovett-Racke AE, Hussain RZ, Northrop S, Choy J, Rocchini A, Matthes L, Chavis JA, Diab A, Drew PD, Racke MK. Peroxisome proliferator-activated receptor alpha agonists as therapy for autoimmune disease. J Immunol. 2004 May 01; 172(9):5790-8. PMID: 15100326.
      View in: PubMed
    76. Diab A, Hussain RZ, Lovett-Racke AE, Chavis JA, Drew PD, Racke MK. Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis. J Neuroimmunol. 2004 Mar; 148(1-2):116-26. PMID: 14975592.
      View in: PubMed
    77. Drew PD, Chavis JA, Bhatt R. Sex steroid regulation of microglial cell activation: relevance to multiple sclerosis. Ann N Y Acad Sci. 2003 Dec; 1007:329-34. PMID: 14993065.
      View in: PubMed
    78. Kielian T, Drew PD. Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation. J Neurosci Res. 2003 Feb 01; 71(3):315-25. PMID: 12526021.
      View in: PubMed
    79. Diab A, Deng C, Smith JD, Hussain RZ, Phanavanh B, Lovett-Racke AE, Drew PD, Racke MK. Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis. J Immunol. 2002 Mar 01; 168(5):2508-15. PMID: 11859145.
      View in: PubMed
    80. Drew PD, S. Burns, And R.L. Archer. Immunosuppressive role of mitoxantrone in central nervous system microglia. Society for Neuroscience Abstracts. 2002.
    81. Barger, S.W., J.A. Chavis, M.M. Porter, A.M. Bodles, And P.D. Drew. Induction of IL-12 in microglia by amyloid beta-peptide: Implication for Alzheimer vaccinations. Society for Neuroscience Abstracts. 2002.
    82. Drew PD, Moss MT, Pasieka TJ, Grose C, Harris WJ, Porter AJ. Multimeric humanized varicella-zoster virus antibody fragments to gH neutralize virus while monomeric fragments do not. J Gen Virol. 2001; 82(Pt 8):1959 - 1963.
    83. Drew PD, R.L. Archer, And J.A. Chavis. Role of doxycycline, a tetracycline derivative, in suppression of microglial cell activation. J. Interferon and Cytokine Research. 2001.
    84. Ball, K., N.F. Cruz, D. Popp, P. Drew, D. Wright, S. Baron, G. Wenger, And G. Dienel. Behavioral training increase local astrocytic metabolic activity but does not alter mild stroke outcome. Society for Neuroscience Abstracts. 2001.
    85. Drew PD, And Chavis, J.A. Immunosuppressive role of prostaglandin (15d-PGJ2) in central nervous system glia. Society for Neuroscience Abstracts. 2000.
    86. Dhillon JK, Drew PD, Porter AJ. Bacterial surface display of an anti-pollutant antibody fragment. Lett Appl Microbiol. 1999; 28(5):350 - 354.
    87. Davies, D.L., And P.D. Drew. Effects of ethanol exposure and withdrawal on microglial in vitro. Society for Neurosciences Abstracts. 1999.
    88. Drew PD, R.B. Berryhill, And J.A. Chavis. steroid hormone regulation of microglia activation. FASEB J. 1999.
    89. Barger, S.W., And P.D. Drew. Inhibition of microglial activation by dehydroepiandrosterone is stimulus-specif. Society for Neurosciences Abstracts. 1999.
    90. Davies, D. L., And P.D. Drew. Effects of ethanol exposure and withdrawal on microglial in vitro. Society for Neurosciences Abstracts. 1999.
    91. Drew PD, And K. D. Phelan. Regulation of MHC class I expression on developing and adult neurons in vitro. Society for Neurosciences Abstracts. 1999.
    92. Becker KG, Nagle JW, Canning RD, Dehejia AM, Polymeropoulos MH, Gado AM, Biddison WE, Drew PD. Molecular cloning and mapping of a novel human KRAB domain-containing C2H2-type zinc finger to chromosome 7q36.1. Genomics. 1997; 41(3):502 - 504.
    93. Jacobson S, Levin MC, Drew PD. Infectious Immune Disorders:HTLV-1: in Neuroimmunology. 1997.
    94. Drew PD, G. Franzoso, W.E. Biddison, U. Siebenlist, And K. Ozato. Interferon regulatory factor and NF-kB proteins physically interact and coordinately regulate the expression of major histocompatibility class I gene expresssion. FASEB J. 1996.
    95. Becker KG, Nagle JW, Canning RD, Biddison WE, Ozato K, Drew PD. Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain. Hum Mol Genet. 1995; 4(4):685 - 691.
    96. Drew PD, G. Franzoso, K.G. Becker, W.E. Biddison, U. Siebenlist, And K. Ozato. NF-kB and interferon regulatory factor proteins physically interact and coordinately regulate major histocompatibility class I gene expresssion. J. Interferon Cytokine Res. 1995.
    97. Dhib-Jalbut, S., Q. Xia, P. Drew, P.T. Swoveland. Differential interferon-beta gene expresssion in neuronal and glia cells in response to virus infection. J. Interferon Cytokine Res. 1995.
    98. Wang, I.-M., J. Blanco, M.-J. Tsai, S. Tsai, P. Drew, And K. Ozato. The phsyical and functional interaction between IRF family proteins and a basal transcription factor TFIIB. J. Interferon Cytokine Res. 1995.
    99. Korenberg, J.R., X.-N. Chen, M. Adams, K. Becker, K. Denison, P. Drew, J. Gatewood, G. Guellaen, L. Hood, D. Hwang, G.M. Huang, C.-C. Liew, And J.C. Venter. So many genes; so little time: A short cut to mapping genes. American J. Human Genet. 1994.
    100. Drew PD, K.G. Becker, M.E. Goldstein, H. Gainer, L.A. Lampson, And K. Ozato. Regulation of major histocompatibility complex class I gene expression in the central nervous system: The role of enhancer binding factors. J. Cellular Biochem. Supplement. 1992.
    101. Drew PD, Ades IZ. Induction of cytochrome P-450 RNA by porphyrogenic agents: on the nature of the coordinate induction with delta-aminolevulinate synthase in tissues of the chicken embryo. Int J Biochem. 1990; 22(6):607 - 610.
    102. Ades, I.Z., P.D. Drew, And G. Ryan. Regulation of production of delta-aminolevulinate synthase in the chick embryo. Symposium: A Century of Porphyria. 1988.
    103. Drew PD, And I.Z. Ades. Regulation of production of delta-aminolevulinate synthase in embryonic chick tissues. J. Cell Biol. 1988.
    104. Ades IZ, Stevens TM, Drew PD. Biogenesis of embryonic chick liver delta-aminolevulinate synthase: regulation of the level of mRNA by hemin. Arch Biochem Biophys. 1987; 253(2):297 - 304.
    105. Ades, I.Z., T.M. Stevens, And P.D. Drew. Regulation of production of liver delta-aminolevulinate synthase by heme. Federal Proceedings. 1986.
    106. Drew, P.D., And I.Z. Ades. Regulation of productioni of liver delta-aminolevulinate synthase: Effesct of testosterone on immune-reactive mass and MRNA of the enzyme. Federal Proceedings. 1986.
    107. Becker, K.G., And P.D. Drew. Novel approaches for the isolation of transcription factors from human brain. NIH Research Festival.
    108. Becker, K.G., M.E. Franco, A. Gado, W.E. Biddison, K. Ozato, And P.D. Drew. Rapid isolation of zinc-finger cDNAs expressed in human brain. NIH Molecular Biology Interest Group.
    109. McCoy J., And P.D. Drew. Effects of thalidomide on macrophage function. Arkansas Cancer Research Center-Partners in Research.
    110. Drew PD, J.A. Chavis, And R.B. Berryhill. Steroid hormone regulation of microglial activation. Effectors of Inflammation in the CNS.
    111. Jennings, B., And P. Drew. The interferon regulatory factor family plays an important role in mediating cellular oncogenesis. Arkansas Cancer Research Center-Partners in Research.
    112. Stauffer, B., K.G. Becker, And P.D. Drew. Characterization of cDNAs encoding C2H2-type zinc finger proteins. NINDS Summer Student Research Program.
    113. Drew PD, J.W. Nagle, R.D. Canning, W.E. Biddison, K. Ozato, And K.G. Becker. Rapid isolation and characterization of transcription factors expressed in human brain by signature sequencing analysis. The 4th International Workshop on the Identification of Transcribed Sequences.
    114. Becker, K.G., M.E. Franco, A.C. Gado, W.E. Biddison, And P.D. Drew. Characterization of C2H2-type zinc finger cDNAs from human brain. NIH Research Festival.
    115. Drew PD, J.W. Nagle, W.E. Biddison, K. Ozato, And K.G. Becker. Isolation and characterization of novel zinc finger cDNAs from human brain by automated DNA sequencing. FASEB J.
    116. Diab, A., P. Drew, C. Deng, And M. Racke. Role of PPAR-gamma in CNS autoimmune demyelination. International Society of Neuroimmunology.
    117. Dienel, G.A., K. Ball, D. Popp, P.D. Drew, And N.F. Cruz. Metabolic labeling of glial tumors by [14C] acetat: High tumor-to-tissue ratio compared to [14C] deoxyglucose. Society for Neuroscience Abstracts.
    118. Engelhoven, R., And P. Drew. Prostaglandin regulation of flial cell antivation. Arkansas High School Science Fair.
    119. Politis, A. D., P.D. Drew, P. Fuschiotti, And P.E. Lipsky. The creation of a primary reviewer pool at the Journal of Immunology: Information management and reviewer commitment.
    120. Drew PD, And J.A. Chavis. Female sex steroid repression of microglial activation. FASEB Summer Conference on Neural Immune Interactions in Development and Disease.
    121. Storer, P.D., J. Xu, And P.D. Drew. Anti-diabetic drugs of the thiazolidinedione class inhibit the activation of microglia and astrocytes:implications for multiple sclerosis. FASEB Summer Conference on Neural Immune Interactions in Development and Disease.
    122. Jennings, B.T., And P.D. Drew. Novel interferon regulatory factor-7: A potential role in oncogenesis. UAMS Student Research Days.
    123. Drew PD, G. Franzoso, K.G. Becker, W.E. Biddison, U. Siebenlist, And K. Ozato. Coordinate regulation of major histocompatiility class I gene expression by NF-kB and interferon regulatory factor proteins. NIH Research Festival.
    124. Phelan, K.D., U.T. Shwe, C.B. Cross, And P.D. Drew. MHC class I plays a critical role in early climbing fiber synapse elimination. Soc. Neurochemistry.
    125. Kielian, T., P. Mayes, P. Drew, And M. Kielian. Microglial responses to S. aureus:modulation of cytokine, co-stimulatory molecule, and Toll-like receptor expression. FASEB Summer Conference on Neural Immune Interactions in Development and Disease.
    126. Becker, K.G., J.W. Nagle, W.E. Biddison, K. Ozato, And P.D. Drew. Automated DNA sequence analysis of transcription factor cDNAs from human brain. Genome Sequencing and Analysis Conference V.
    127. Drew PD, And K.D. Phelan. Regulation of MHC class I expression on CNS neurons. FASEB J.
    128. Ozato, K., P.D. Drew, M.S. Marks, K.G. Becker, P.T. Massa, And D.E. McFarlin. Regulation of MHC class I gene expression in the central nervous system.
    129. Kane, C.J.M, K.D. Phelan, P.D. Drew. Neuroimmune targets of alcohol across the lifespan; the role of microglia. Alcohol (Special Issue).
    130. Becker, K.G., Nagle, J.W., K. Ozato, W.E. Biddison, And P.D. Drew. Isolation of transcription factor cDNAs from human brain by automated DNA sequencing. NINDS Research Day.
    131. Kane, C.J.M., K.D. Phelan, J.C. Douglas, G. Wagoner, J. Johnson, J. Xu, P.S. Phelan, P.D. Drew. Immune response to alcohol in th eadolescent and adult mouse brain. Society of Neuroscience Annual Meeting.
    132. Drew. P.D., L. Han, R.R. Smith, J.C. Douglas, K.D. Phelan, C. J. M. Kane. Role of Neuroimmune Signaling Molecules in the Neuropathology of Fetal Alcohol Spectrum Disorders. Neuroimmune Pharmacology. S13.
    133. Drew PD, W.E. Biddison, K.Ozato, And K.G. Becker. Signature sequencing analysis: Cloning of transcriptioin factors from human brain. The Institute for Computational Sciences and Informatics Colloquium.
    134. Drew PD, K.G. Becker, K. Ozato, And D.E. McFarlin. Transcription factor regulation of major histocompatibility class I expression in the central nervous system. NIH Research Festival.
    135. Brown, S, K. Phelan, And P. Drew. Class I expression and regulation in primary and transformed neuronal cells. Arkansas Cancer Research Center-Partners in Research.
    136. Drew PD, J.W. Nagle, W.E. Biddison, K. Ozato, And K.G. Becker. Cloing and characterization of novel zinc finger CDNAs from human brain. NINDS Reserach Day.
    137. Drew PD, K.G. Becker, V. Bours, U. Siebenlist, K. Ozato, And D.E. McFarlin. Major histocompatibility class I gene expression in CNS cell: Modulation of gene expression. NINDS Reserach Day.
    138. Drew PD, K. Ozato, And D.E. McFarlin. Regulation of MHC Class I expression in neuronal cells. Gordon Research Conference on Neuroimmunology.
    139. Becker, K.G., M.S. Marks, P.D. Drew, J.R. Flanagan, And K. Ozato. Protein characterization of H2RI-BP, a ranscription factor binding the MHC I promoter. NIH Research Festival.
    140. Welbon, C., And P.D. Drew. Cloning of CDNAs encoding tri-nucleotide repeats: relevance to neurolgoical disorders. NINDS Summer Student Research Program.
    141. Drew PD, And S. Burns. Immunosuppressive role of mitoxantrone in central nervous system microglia. FASEB Summer Conference on Neural Immune Interactions in Development and Disease.
    142. Becker, K.G., J.W. Nagle, R. D. Canning, W.E. Biddison, K. Ozato, And P.D. Drew. Cloing and characterization of transcription factors by signature sequencing analysis. Human Genome 1994: The Genes And Beyond.
    143. Drew PD, J.W. Nagle, R.D. Canning, W.E. Biddison, K. Ozato, And K.G. Becker. Rapid isolation and characterization of transcription factors expressed in human brain by signature sequencing analysis. Genome Sequencing and Analysis Conference VI.
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