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Mathias Brochhausen

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentBiomedical Informatics, College of Medicine
Address474 Stephens Spine Center
501 Jack Stephens Drive
Mail Slot # 782
Little Rock AR 72205
Phone501-603-1765
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    Other Positions
    TitleAssociate Professor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentMedical Humanities, College of Medicine


    Collapse Research Funds 
    Collapse principal investigator
    Funding Agency: NIH/Nat. Inst. of General Medical Sciences - Title: CAFE: Comparative Assessment Framework for Environments of Trauma Care - Award Number: 1 R01 GM111324-01A1 - Start Date: 2015-03-05

    Funding Agency: NIH/Nat. Inst. of General Medical Sciences - Title: CAFE: Comparative Assessment Framework for Environments of Trauma Care - Award Number: 5 R01 GM111324-02 - Start Date: 2015-03-05

    Funding Agency: NIH/Nat. Inst. of General Medical Sciences - Title: CAFE: Comparative Assessment Framework for Environments of Trauma Care - Award Number: 5 R01 GM111324-03 - Start Date: 2015-03-05

    Funding Agency: NIH/Nat. Inst. of General Medical Sciences - Title: CAFE: Comparative Assessment Framework for Environments of Trauma Care - Award Number: 5 R01 GM111324-04 - Start Date: 2015-03-05

    Funding Agency: NIH/Nat. Inst. of General Medical Sciences - Title: CAFE: Comparative Assessment Framework for Environments of Trauma Care - Award Number: 5 R01 GM111324-05 - Start Date: 2015-03-05

    Funding Agency: NIH/Nat. Inst. of General Medical Sciences - Title: CAFE: Comparative Assessment Framework for Environments of Trauma Care - Award Number: 1 R01 GM111324-01A1 - Total direct costs: $446,352 - Start Date: 2015-03-05

    Pass Through Agency: University of Pittsburgh - Funding Agency: DHHS - Biomedical Advanced Research and Development Authority - Title: Addressing gaps in clinically useful evidence on drug-drug interactions - Award Number: 0040478 (124095-2) - Total direct costs: $68,978 - Start Date: 2014-02-15


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Judkins J, Tay-Sontheimer J, Boyce RD, Brochhausen M. Extending the DIDEO ontology to include entities from the natural product drug interaction domain of discourse. J Biomed Semantics. 2018 May 09; 9(1):15. PMID: 29743102.
      View in: PubMed
    2. Blobel B, Brochhausen M, Ruotsalainen P. Modeling the Personal Health Ecosystem. Stud Health Technol Inform. 2018; 249:3-16. PMID: 29866950.
      View in: PubMed
    3. Brochhausen M, Bona J, Blobel B. The Role of Axiomatically-Rich Ontologies in Transforming Medical Data to Knowledge. Stud Health Technol Inform. 2018; 249:38-49. PMID: 29866954.
      View in: PubMed
    4. Utecht J, Brochhausen M, Judkins J, Schneider J, Boyce RD. Formalizing Evidence Type Definitions for Drug-Drug Interaction Studies to Improve Evidence Base Curation. Stud Health Technol Inform. 2017; 245:960-964. PMID: 29295242.
      View in: PubMed
    5. Hogan WR, Wagner MM, Brochhausen M, Levander J, Brown ST, Millett N, DePasse J, Hanna J. The Apollo Structured Vocabulary: an OWL2 ontology of phenomena in infectious disease epidemiology and population biology for use in epidemic simulation. J Biomed Semantics. 2016 Aug 18; 7:50. PMID: 27538448; PMCID: PMC4989460.
      View in: PubMed, PubMed Central
    6. Judkins J, Utecht J, Brochhausen M. Easy Extraction of Terms and Definitions with OWL2TL. CEUR Workshop Proc. 2016 Aug; 1747. PMID: 28035214.
      View in: PubMed
    7. Utecht J, Judkins J, Otte JN, Colvin T, Rogers N, Rose R, Alvi M, Hicks A, Ball J, Bowman SM, Maxson RT, Nabaweesi R, Pradhan R, Sanddal ND, Tudoreanu ME, Winchell RJ, Brochhausen M. OOSTT: a Resource for Analyzing the Organizational Structures of Trauma Centers and Trauma Systems. CEUR Workshop Proc. 2016 Aug; 1747. PMID: 28217041.
      View in: PubMed
    8. Hicks A, Hanna J, Welch D, Brochhausen M, Hogan WR. The ontology of medically related social entities: recent developments. J Biomed Semantics. 2016 Jul 12; 7:47. PMID: 27406187; PMCID: PMC4942889.
      View in: PubMed, PubMed Central
    9. Brochhausen M, Zheng J, Birtwell D, Williams H, Masci AM, Ellis HJ, Stoeckert CJ. OBIB-a novel ontology for biobanking. J Biomed Semantics. 2016; 7:23. PMID: 27148435; PMCID: PMC4855778.
      View in: PubMed, PubMed Central
    10. Bandrowski A, Brinkman R, Brochhausen M, Brush MH, Bug B, Chibucos MC, Clancy K, Courtot M, Derom D, Dumontier M, Fan L, Fostel J, Fragoso G, Gibson F, Gonzalez-Beltran A, Haendel MA, He Y, Heiskanen M, Hernandez-Boussard T, Jensen M, Lin Y, Lister AL, Lord P, Malone J, Manduchi E, McGee M, Morrison N, Overton JA, Parkinson H, Peters B, Rocca-Serra P, Ruttenberg A, Sansone SA, Scheuermann RH, Schober D, Smith B, Soldatova LN, Stoeckert CJ, Taylor CF, Torniai C, Turner JA, Vita R, Whetzel PL, Zheng J. The Ontology for Biomedical Investigations. PLoS One. 2016; 11(4):e0154556. PMID: 27128319.
      View in: PubMed
    11. Utecht J, Brochhausen M. Measuring the Usability of Triple Stores for Knowledge Management on Trauma Care Organizations. CEUR Workshop Proc. 2015 Dec; 1546:241-242. PMID: 27013932.
      View in: PubMed
    12. Smith B, Arabandi S, Brochhausen M, Calhoun M, Ciccarese P, Doyle S, Gibaud B, Goldberg I, Kahn CE, Overton J, Tomaszewski J, Gurcan M. Biomedical imaging ontologies: A survey and proposal for future work. J Pathol Inform. 2015; 6:37. PMID: 26167381; PMCID: PMC4485195.
      View in: PubMed, PubMed Central
    13. Ayvaz S, Horn J, Hassanzadeh O, Zhu Q, Stan J, Tatonetti NP, Vilar S, Brochhausen M, Samwald M, Rastegar-Mojarad M, Dumontier M, Boyce RD. Toward a complete dataset of drug-drug interaction information from publicly available sources. J Biomed Inform. 2015 Jun; 55:206-17. PMID: 25917055; PMCID: PMC4464899.
      View in: PubMed, PubMed Central
    14. Bian J, Xie M, Hudson TJ, Eswaran H, Brochhausen M, Hanna J, Hogan WR. CollaborationViz: interactive visual exploration of biomedical research collaboration networks. PLoS One. 2014; 9(11):e111928. PMID: 25405477; PMCID: PMC4236011.
      View in: PubMed, PubMed Central
    15. Fransson MN, Rial-Sebbag E, Brochhausen M, Litton JE. Toward a common language for biobanking. Eur J Hum Genet. 2015 Jan; 23(1):22-8. PMID: 24713663; PMCID: PMC4266732.
      View in: PubMed, PubMed Central
    16. Ayvaz S, Zhu Q, Hochheiser H, Brochhausen M, Horn J, Dumontier M, Samwald M, Boyce RD. Drug-drug interaction data source survey and linking. AMIA Jt Summits Transl Sci Proc. 2014; 2014:16. PMID: 25717393; PMCID: PMC4333686.
      View in: PubMed, PubMed Central
    17. Hanna J, Joseph E, Brochhausen M, Hogan WR. Building a drug ontology based on RxNorm and other sources. J Biomed Semantics. 2013 Dec 18; 4(1):44. PMID: 24345026; PMCID: PMC3931349.
      View in: PubMed, PubMed Central
    18. Brochhausen M, Fransson MN, Kanaskar NV, Eriksson M, Merino-Martinez R, Hall RA, Norlin L, Kjellqvist S, Hortlund M, Topaloglu U, Hogan WR, Litton JE. Developing a semantically rich ontology for the biobank-administration domain. J Biomed Semantics. 2013 Oct 08; 4(1):23. PMID: 24103726; PMCID: PMC4021870.
      View in: PubMed, PubMed Central
    19. Blobel B, Goossen W, Brochhausen M. Clinical modeling--a critical analysis. Int J Med Inform. 2014 Jan; 83(1):57-69. PMID: 24161541.
      View in: PubMed
    20. Slaughter L, Brochhausen M, Hogan W, Nytrø Ø. The core clinical protocol ontology (C2PO): A realist ontology for representing the recommendations within clinical guidelines. Stud Health Technol Inform. 2013; 192:997. PMID: 23920771.
      View in: PubMed
    21. Brochhausen M, Almeida MA, Slaughter M. Towards a formal representation of document acts and the resulting legal entities. 2013; 120-139.
    22. Hogan WR, Brochhausen M, Smith B. A Call to Urgent Action On Standard Ontologies for Translational Science. Clinical and Translation Science 6(2). 2013; 157.
    23. Hogan WR, Hanna J, Joseph E, Brochhausen M. Towards a Consistent and Scientifically Accurate Drug Ontology. CEUR Workshop Proc. 2013; 1060:68-73. PMID: 27867326.
      View in: PubMed
    24. Brochhausen M, Fransson MN, Eriksson M, Merino-Martinez R, Norlin L, Kjellqvist S, Anderberg M, Hogan WR, Litton JE. Developing an ontology for sharing biobank data based on the BBMRI minimum data set MIABIS. Ontologies in Biomedicine and Life Sciences (OBML) 2012. 2012.
    25. Blobel B, Brochhausen M, González C, Lopez DM, Oemig F. A system-theoretical, architecture-based approach to ontology management. Stud Health Technol Inform. 2012; 180:1087-9. PMID: 22874362.
      View in: PubMed
    26. Brochhausen M, Blobel B. Architectural approach for providing relations in biomedical terminologies and ontologies. Stud Health Technol Inform. 2011; 169:739-43. PMID: 21893845.
      View in: PubMed
    27. Martin L, Anguita A, Graf N, Tsiknakis M, Brochhausen M, Rüping S, Bucur A, Sfakianakis S, Sengstag T, Buffa F, Stenzhorn H. ACGT: advancing clinico-genomic trials on cancer - four years of experience. Stud Health Technol Inform. 2011; 169:734-8. PMID: 21893844.
      View in: PubMed
    28. EpSOS contributers. epSOS learnings: sematnics a matter of patient safety and the ultimate health care delivery system. Swiss Medical Informatics. 2011; (73):23-26.
    29. Brochhausen M, Spear AD, Cocos C, Weiler G, Martín L, Anguita A, Stenzhorn H, Daskalaki E, Schera F, Schwarz U, Sfakianakis S, Kiefer S, Dörr M, Graf N, Tsiknakis M. The ACGT Master Ontology and its applications--towards an ontology-driven cancer research and management system. J Biomed Inform. 2011 Feb; 44(1):8-25. PMID: 20438862.
      View in: PubMed
    30. Smith B, Brochhausen M. Putting biomedical ontologies to work. Methods Inf Med. 2010; 49(2):135-40. PMID: 20135080; PMCID: PMC3116518.
      View in: PubMed, PubMed Central
    31. Stenzhorn H, Weiler G, Brochhausen M, Schera F, Kritsotakis V, Tsiknakis M, Kiefer S, Graf N. The ObTiMA system - ontology-based managing of clinical trials. Stud Health Technol Inform. 2010; 160(Pt 2):1090-4. PMID: 20841852.
      View in: PubMed
    32. Brochhausen M, Slaughter L, Stenzhorn H, Graf N. User-specific perspectives on ontologies. Stud Health Technol Inform. 2010; 156:114-21. PMID: 20543346.
      View in: PubMed
    33. Grigonyte G, Brochhausen M, Martin L, Tsiknakis M, Haller J. Evaluating Ontologies with NLP-Based Terminologies – A Case Study on ACGT and Its Master Ontology. Formal Ontology in Information Systems - Proceedings of the Sixth International Conference (FOIS 2010). 2010.
    34. Brochhausen M, Slaughter L. Patient Empowerment by Ontology-Based Multi-lingual Systems. IFMBE Proceedings 25/XII. 2009.
    35. Wagner M, Breiner T, Betz T, Bernhardt I, Pütz N, Weichert F, Shamaa A, Brochhausen M, Awad S, Richards T, Groh A, Linder R, Landes CA. [Virtual tissue. Quaoaring]. Pathologe. 2008 Nov; 29 Suppl 2:123-8. PMID: 19039616.
      View in: PubMed
    36. Tsiknakis M, Brochhausen M, Nabrzyski J, Pucacki J, Sfakianakis SG, Potamias G, Desmedt C, Kafetzopoulos D. A semantic grid infrastructure enabling integrated access and analysis of multilevel biomedical data in support of postgenomic clinical trials on cancer. IEEE Trans Inf Technol Biomed. 2008 Mar; 12(2):205-17. PMID: 18348950.
      View in: PubMed
    37. Smith B, Brochhausen M. Establishing and harmonizing ontologies in an interdisciplinary health care clinical research environment. Stud Health Technol Inform. 2008; 134:219-33. PMID: 18376049.
      View in: PubMed
    38. Martin L, Anguita A, Maojo V, Bonsma E, Bucur AID, Vrijnsen J, Brochhausen M, Cocos C, Stenzhorn H, Tsiknakis M, Doerr M, Kondylakis H. Ontology Based Integration of Distributed and Heterogeneous Data Sources in ACGT. Proceedings of the First International Conference on Health Informatics, HEALTHINF 2008. 2008.
    39. Brochhausen M, Weiler G, Cocos C, Stenzhorn H, Graf N, Doerr M, Tsinakis M. The ACGT Master Ontology on Cancer - a New Terminology Source for Oncological Practice. Proceedings of the 21st IEEE International Symposium on Computer-Based Medical Systems. 2008.
    40. Brochhausen M, Weiler G, Martin L, Cocos C, Stenzhorn H, Graf N, Doerr M, Tsinakis M, Smith B. Applications of the ACGT Master Ontology on Cancer. Proceedings of 4th International IFIP Workshop On Semantic Web & Web Semantics (OTM 2008: Workshops), LNCS 5333. 2008.
    41. Brochhausen M. How Upper Level Ontologies Deal With Functions and Other Realizable Entities. Biomedical Computation Review. 2008; 25.
    42. Tsiknakis M, Rueping S, Martin L, Sfakianakis S, Bucur A, Sengstag T, Brochhausen M, Pucaski J, Graf N. Developing a European grid infrastructure for cancer research: vision, architecture and services. Ecancermedicalscience. 2007; 1:56. PMID: 22275955; PMCID: PMC3223975.
      View in: PubMed, PubMed Central
    43. Weiler G, Brochhausen M, Graf N, Schera F, Hoppe A, Kiefer S. Ontology based data management systems for post-genomic clinical trials within a European Grid Infrastructure for Cancer Research. Conf Proc IEEE Eng Med Biol Soc. 2007; 2007:6435-8. PMID: 18003495.
      View in: PubMed
    44. Hainaut JL, Rundensteiner EA, Kirchberg M, Bertolotto M, Brochhausen M, Chen P, Sisaid Cherfi S, Doerr M, Han H, Hartmann S, Parsons J, Poels G, Rolland C, Trujillo J, Yu E, Zimlanyi E. Advances in Conceptual Modeling - Foundations and Applications · ER 2007 Workshops CMLSA, FP-UML, ONISW, QoIS, RIGiM, SeCoGIS, Auckland, New Zealand, November 5-9, 2007, Proceedings. 2007.
    45. Brochhausen M. The derives_from relation in biomedical ontologies. Stud Health Technol Inform. 2006; 124:769-74. PMID: 17108607.
      View in: PubMed
    46. Brochhausen M. Wissenschaftsphilosophische Aspekte der Evolutionären Anthropologie. Studie zum Ursprung des anatomisch modernen Menschen. Gardez! Verlag. 2005.
    47. Brochhausen M. Evolution und Gesellschaft von einem naturalistischen Standpunkt aus. Erwägen Wissen Ethik. 2005; 16(3):378-380.
    48. Brochhausen C, Brochhausen M, Seyberth HW. In wessen bestem Interesse? Mögliche finanzielle Interessenkonflikte in der klinischen Forschung und ihre Relevanz für die Pädiatrie. 2003; 251-263.
    49. Brochhausen C, Brochhausen M, Seyberth HW. Pädiatrie zwischen Patientenschutz und Therapiesicherheit – eine interdisziplinäre Herausforderung. 2002; 458-471.
    50. Brochhausen C, Brochhausen M. Relativistische Wissenschaftskritik als epistemologischer Ansatz in der Historischen Epidemiologie. 2001; 59-72.
    51. Brochhausen M. Krankheit als subjektives Ereignis. 2001; 13-20.
    52. Kerstjens DP, Brochhausen M. Krankheiten als natürliche Arten. Schnittstelle Mensch – Umwelt in Vergangenheit, Gegenwart und Zukunft. 2000.
    53. Brochhausen M. Understanding Recent Apes As Parallel Models in Paleoanthropology. Anthropologie. (2):115-118.
    54. Elmasri R, Doerr M, Brochhausen M, Han H. Proceedings of the 2nd International Workshop on Ontologies and Information Systems for the Semantic Web, ONISW 2008.
    55. Schulz S, Brochhausen M, Hoehndorf R. Higgs Bosons, Mars Missions, and Unicorn Delusions: How to Deal with Terms of Dubious Reference in Scientific Ontologies. International Conference on Biomedical Ontologies (ICBO) 2011, University at Buffalo, Buffalo NY, 2011.
    56. Almeida MB, Slaughter L, Brochhausen M. Towards an ontology of document acts: Introducing a document act template for healthcare. OTM 2012 Workshop, LNCS 7567.
    57. Schneider L, Brochhausen M, Koepsell D. On Some Best Practices in Large-Scale Ontology Development: The Chronious Ontology Suite as a Case Study. Formal Ontology Meets Industry 5th International Workshop Proceedings.
    58. Schneider L, Brochhausen M. The CHRONIUS Ontology Suite: Methodology and Design Principles. International Conference on Biomedical Ontologies (ICBO) 2011, University at Buffalo, Buffalo NY, 2011.
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