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Alan Diekman

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentBiochemistry & Molecular Biology, College of Medicine
DivisionBiochem & Molecular Glycoconjugate
AddressB421E Biomedical Research I
325 S. Elm St.
Mail Slot # 516
Little Rock AR 72205
Phone501-686-5812
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    Other Positions
    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentUrology, College of Medicine


    Collapse Research Funds 
    Collapse research activities
    W81XWH-11-1-0369     (DIEKMAN, ALAN)May 1, 2011 - Sep 30, 2012
    US Department of the Army
    Prostate cancer biomarker development based on galectin-3/prostate specific antigen (PSA) interactions
    Role: Principal Investigator

    R01GM089001     (RANEY, KEVIN D)Sep 1, 2009 - Aug 31, 2014
    NIH/NIGMS
    Mechanisms of RNA binding and remodeling proteins
    Role: Co-Investigator

    R01HD050540     (DIEKMAN, ALAN B)Aug 5, 2005 - May 31, 2010
    NIH/NICHD
    Role of galectin-3 in genital tract immunosuppression
    Role: Principal Investigator

    R03HD041524     (DIEKMAN, ALAN B)Sep 1, 2002 - Aug 31, 2005
    NIH/NICHD
    Role of GPI-Anchored CD52 Glycoprotein in Sperm Function
    Role: Principal Investigator

    NIH HD35523     (DIEKMAN, ALAN)Aug 1, 2002 - Jul 31, 2003
    University of Virginia
    Immunologic Mechanisms in Human Female Infertility Sub Contract of NIH HD35523
    Role: Principal Investigator

    R43HD035771     (DIEKMAN, ALAN B)Sep 29, 1997 - Sep 30, 1999
    NIH/NICHD
    RECOMBINANT ANTIBODIES AS INTRA VAGINAL SPERMICIDES
    Role: Principal Investigator

    F32HD008002     (DIEKMAN, ALAN B)Aug 6, 1996
    NIH/NICHD
    HUMAN SPERM ZONA BINDING PROTEIN
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Zimmerman SM, Besio R, Heard-Lipsmeyer ME, Dimori M, Castagnola P, Swain FL, Gaddy D, Diekman AB, Morello R. Expression characterization and functional implication of the collagen-modifying Leprecan proteins in mouse gonadal tissue and mature sperm. AIMS Genet. 2018; 5(1):24-40. PMID: 30417103.
      View in: PubMed
    2. Niederhoffer EC, Cline SD, Osheroff N, Simmons JM, Diekman AB, Franklin DS, Abali EE, Bateman RC, Fontes JD, Lindsley JE, Pearson D, Rubenstein PA, Slaughter CA, Bernstein JA, Hyland KM, Park VM, Sobering AK, Weiler TA, Dasgupta S. Teaching Biochemistry and Genetics to Students of Dentistry, Medicine, and Pharmacy 6th International Conference of the Association of Biochemistry Educators (ABE) Clearwater Beach, FL, USA, May 7-11, 2017. Med Sci Educ. 2017 Dec; 27(4):855-859. PMID: 29291139.
      View in: PubMed
    3. Osheroff N, Niederhoffer EC, Sabina RL, Cline SD, Wimmer MJ, Franklin DS, Diekman AB, Hogg T, Kearney KR, King SC, Pearson D, Slaughter CA, Thompson K. Teaching Biochemistry to Students of Medicine, Pharmacy & Dentistry: 5th International Conference of the Association of Biochemistry Course Directors (ABCD) Santa Fe, NM, USA, May 3-7, 2015. Med Sci Educ. 2015 Dec; 25(4):473-477. PMID: 26693393.
      View in: PubMed
    4. Kovak MR, Saraswati S, Schoen DJ, Diekman AB. Investigation of galectin-3 function in the reproductive tract by identification of binding ligands in human seminal plasma. Am J Reprod Immunol. 2014 Oct; 72(4):403-12. PMID: 24863808.
      View in: PubMed
    5. Kovak MR, Saraswati S, Diekman AB. Investigation of Galectin-3 Binding Ligands in Human Seminal Plasma Using a Proteomic Approach. Andrology 1 Suppl. 2. 2013; 97.
    6. Diekman A, Kovak M, Goddard S, Gilbride R, Block A, Saraswati S. Molecular Interactions of Galectin-3 and PSA in Human Semen, Prostate, and Prostate Tumors. Journal of Andrology 33 Suppl. 2012; 49.
    7. Saraswati S, Block AS, Davidson MK, Rank RG, Mahadevan M, Diekman AB. Galectin-3 is a substrate for prostate specific antigen (PSA) in human seminal plasma. Prostate. 2011 Feb 01; 71(2):197-208. PMID: 20672323.
      View in: PubMed
    8. Saraswati S, Block AS, Davidson MK, Rank RG, Mahadevan M, Diekman AB. Galectin-3 is a substrate of prostate specific antigen (PSA) in human seminal plasma. The Prostate. 2011; 71:197-208.
    9. Block AS, Saraswati S, Lichti CF, Mahadevan M, Diekman AB. Co-purification of Mac-2 binding protein with galectin-3 and association with prostasomes in human semen. Prostate. 2011 May 15; 71(7):711-21. PMID: 21031433.
      View in: PubMed
    10. Naaby-Hansen S, Diekman A, Shetty J, Flickinger CJ, Westbrook A, Herr JC. Identification of calcium-binding proteins associated with the human sperm plasma membrane. Reprod Biol Endocrinol. 2010 Jan 15; 8:6. PMID: 20078857.
      View in: PubMed
    11. Jones JL, Saraswati S, Block AS, Lichti CF, Mahadevan M, Diekman AB. Galectin-3 is associated with prostasomes in human semen. Glycoconj J. 2010 Feb; 27(2):227-36. PMID: 19830550.
      View in: PubMed
    12. Gilbride, RJ, Block, AS, Saraswati, S, Diekman AB. Molecular Interactions between Galectin-3 and Prostate Specific Antigen (PSA) Secreted by Prostate Cancer Cell Lines. Journal of Andrology March/April Suppl. 2009.
    13. Tyler CD, Lichti CF, Diekman AB, Foley SL. Evaluation of differentially expressed proteins following serum exposure in avian pathogenic Escherichia coli. Avian Dis. 2008 Mar; 52(1):23-7. PMID: 18459291.
      View in: PubMed
    14. Tyler C, Lichti C, Diekman AB, Foley S. Evaluation of differentially expressed proteins following complement exposure in avian pathogenic Escherichia coli. Avian Diseases. 2008; 52:23-27.
    15. Saraswati S, Block AS, Diekman AB. Galectin-3 is a substrate for prostate specific antigen (PSA). Journal of Andrology March/April Suppl. 2008.
    16. Parry S, Wong NK, Easton RL, Panico M, Haslam SM, Morris HR, Anderson P, Klotz KL, Herr JC, Diekman AB, Dell A. The sperm agglutination antigen-1 (SAGA-1) glycoforms of CD52 are O-glycosylated. Glycobiology. 2007 Oct; 17(10):1120-6. PMID: 17640971.
      View in: PubMed
    17. Westbrook VA, Schoppee PD, Diekman AB, Klotz KL, Allietta M, Hogan KT, Slingluff CL, Patterson JW, Frierson HF, Irvin WP, Flickinger CJ, Coppola MA, Herr JC. Genomic organization, incidence, and localization of the SPAN-x family of cancer-testis antigens in melanoma tumors and cell lines. Clin Cancer Res. 2004 Jan 01; 10(1 Pt 1):101-12. PMID: 14734458.
      View in: PubMed
    18. Diekman AB, Herr, JC. The Third International Conference on the Epididymis. Human sperm surface antigens acquired during epididymal maturation. 2004.
    19. Shetty J, Wolkowicz MJ, Digilio LC, Klotz KL, Jayes FL, Diekman AB, Westbrook VA, Farris EM, Hao Z, Coonrod SA, Flickinger CJ, Herr JC. SAMP14, a novel, acrosomal membrane-associated, glycosylphosphatidylinositol-anchored member of the Ly-6/urokinase-type plasminogen activator receptor superfamily with a role in sperm-egg interaction. J Biol Chem. 2003 Aug 15; 278(33):30506-15. PMID: 12788941.
      View in: PubMed
    20. Diekman AB. Glycoconjugates in sperm function and gamete interactions: how much sugar does it take to sweet-talk the egg? Cell Mol Life Sci. 2003 Feb; 60(2):298-308. PMID: 12678495.
      View in: PubMed
    21. Mandal A, Klotz KL, Shetty J, Jayes FL, Wolkowicz MJ, Bolling LC, Coonrod SA, Black MB, Diekman AB, Haystead TA, Flickinger CJ, Herr JC. SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa. Biol Reprod. 2003 May; 68(5):1525-37. PMID: 12606493.
      View in: PubMed
    22. McCauley TC, Kurth BE, Norton EJ, Klotz KL, Westbrook VA, Rao AJ, Herr JC, Diekman AB. Analysis of a human sperm CD52 glycoform in primates: identification of an animal model for immunocontraceptive vaccine development. Biol Reprod. 2002 Jun; 66(6):1681-8. PMID: 12021047.
      View in: PubMed
    23. Diekman AB, Herr, JC, Freemerman, AJ, Coonrod, SA. Proceedings of the Fifth World Congress on Fertility and Sterility. Recent advances in the path to a contraceptive vaccine. 1995.
    24. Cronkite DL, Diekman AB, Lewallen B, Phillips L. Aminotransferase and the production of alanine during hyperosmotic stress in Paramecium calkinsi. J Eukaryot Microbiol. 1993; 40(6):796 - 800.
    25. Saraswati S, Block AS, Diekman AB. Carbohydrate Recognition: Biological Problems, Methods, and Applications. Galectins and their role in various biological processes. 7.
    26. Diekman AB, Goldberg E. Immunology of Reproduction. What are their private specificities.
    27. Westbrock VA, Diekman AB, Herr JC. Introduction to Mammalian Reproduction. Novel signaling pathways involved in sperm acquisition of fertilizing capacity.
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