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Nancy Rusch

TitleDistinguished Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentCollege of Medicine
Address306B Biomedical Research I
325 S. Elm St.
Mail Slot # 611
Little Rock AR 72205
Phone501-686-8038
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    Other Roles
    Chair, Department of Pharmacology and Toxicology Co-Director, Connect Arkansas Research Scholars (CARS) program

    Collapse Research 
    Collapse research activities and funding
    GR019316     (RUSCH, NANCY JEAN)Jul 1, 2023 - Jun 17, 2024
    University of Arkansas at Pine Bluff
    Connect Arkansas Research Scholars (CARS) Program
    Role: Principal Investigator
    TL1TR003109     (SEXTON, KEVIN WAYNE)Jul 1, 2019 - Jun 30, 2024
    NIH
    J. NRSA Training
    Role: Principal Investigator
    Sturgis FY18     (RUSCH, NANCY JEAN)Nov 15, 2017 - Dec 31, 2019
    UAMS College of Medicine
    No FP attached
    Role: Principal Investigator
    U54TR001629     (JAMES, LAURA P)Sep 26, 2017 - Aug 31, 2019
    NIH
    Expanding Translational Research in Arkansas
    Role: Co-Investigator
    17GRNT33670970     (RHEE, SUNG)Jul 1, 2017 - Jun 30, 2019
    American Heart Association
    Beta adrenergic receptor-mediated vasodilation of cerebral collateral arteries- Resubmission- Resubmission
    Role: Principal Investigator
    16PRE30830010     (SHRUM, STEPHEN)Jul 1, 2016 - Jun 30, 2018
    American Heart Association (SouthWest Affiliate)
    Role of mitoBK channels in rat renal cold preservation
    Role: Principal Investigator
    117-1009851     (RUSCH, NANCY)Jul 1, 2015 - Jun 30, 2018
    UAMS College of Medicine
    T32 Campus Match funding Account
    Role: Principal Investigator
    117-1002506     (RUSCH, NANCY)Jul 1, 2015 - Jun 30, 2016
    UAMS College of Medicine
    Pharmacology Dept GEF Account
    Role: Principal Investigator
    117-1005242     (RUSCH, NANCY)Jul 1, 2015 - Jun 30, 2016
    UAMS College of Medicine
    Dr. Rusch Start Up Account
    Role: Principal Investigator
    117-1005492-2     (RUSCH, NANCY JEAN)Jul 1, 2015 - Jun 30, 2016
    UAMS College of Medicine
    No FP attached
    Role: Principal Investigator
    P20GM109005     (BOERMA, MARJAN)Jun 24, 2015 - May 31, 2025
    NIH
    Center for Studies of Host Response to Cancer Therapy
    Role: Co-Investigator
    R21CA187325     (RUSCH, NANCY J)Mar 9, 2015 - Feb 28, 2018
    NIH
    Doxorubicin suppression of lymphatic function and therapeutic reversal
    Role: Principal Investigator
    13GRNT14590001     (RUSCH, NANCY)Jan 1, 2013 - Dec 31, 2014
    American Heart Association (SouthWest Affiliate)
    AHA-Vascular TRPC3 Channels as Antihypertensive Targets
    Role: Principal Investigator
    R01HL097107     (RHEE, SUNG W)Mar 15, 2010 - Feb 29, 2016
    NIH
    PSD95 scaffolding of vascular K+ channels in hypertension
    Role: Co-Investigator
    R01HL095846     (PALADE, PHILIP T.)Jan 22, 2010 - Nov 30, 2014
    NIH
    MicroRNA to decrease vascular CaV1.2 in hypertension
    Role: Co-Investigator
    R01HL093526     (RUSCH, NANCY J)May 5, 2009 - Oct 31, 2014
    NIH
    Long-term Antihypertensive Therapy by Delivery of the BK Channel Gene to VSMCs
    Role: Principal Investigator
    R01HL083013     (RUSCH, NANCY J)Aug 1, 2005 - Jul 31, 2010
    NIH
    Calcium Channels in Neonatal Pulmonary Hypertension
    Role: Principal Investigator
    R01HL064806     (RUSCH, NANCY J)May 1, 2000 - Jun 30, 2014
    NIH
    Vascular Calcium Channel Expression in Hypertension
    Role: Principal Investigator
    R01HL059238     (RUSCH, NANCY J)Mar 1, 1998 - Nov 30, 2006
    NIH
    Role of Cerebrovascular K+ Channels in Hypertension
    Role: Principal Investigator
    R03TW000350     (RUSCH, NANCY J)Sep 30, 1993 - Sep 29, 1995
    NIH
    REGULATION OF VENOUS MUSCLE K+ CHANNELS
    Role: Principal Investigator
    R29HL040474     (RUSCH, NANCY J)Aug 1, 1988 - Jul 31, 1993
    NIH
    VASCULAR MUSCLE CALCIUM CURRENTS IN HYPERTENSION
    Role: Principal Investigator
    F32HL006907     (RUSCH, NANCY J)Jan 1, 1985
    NIH
    TROPHIC EFFECT OF SYMPATHETIC NERVES ON ARTERIAL MUSCLE
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Pal S, Bagchi AK, Henry DS, Landes RD, Mu S, Rhee SW, Rusch NJ, Stolarz AJ. Rhythmic Contractions of Lymph Vessels and Lymph Flow Are Disrupted in Hypertensive Rats. Hypertension. 2024 Nov 06. PMID: 39502071.
      View in: PubMed
    2. Shahror RA, Shosha E, Morris C, Wild M, Mu S, Csanyi G, Boerma M, Rusch NJ, Fouda AY. Deletion of myeloid HDAC3 promotes efferocytosis to ameliorate retinal ischemic injury. J Neuroinflammation. 2024 Jul 12; 21(1):170. PMID: 38997746.
      View in: PubMed
    3. Leung YK, Lee SG, Wang J, Guruvaiah P, Rusch NJ, Ho SM, Park C, Kim K. The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/?-catenin Signaling via Epigenetic Dysregulation that Enhances Sp1-? catenin-p300 Interactions in Hepatocellular Carcinoma. Adv Sci (Weinh). 2024 Aug; 11(29):e2308539. PMID: 38790135.
      View in: PubMed
    4. Shahror RA, Morris CA, Mohammed AA, Wild M, Zaman B, Mitchell CD, Phillips PH, Rusch NJ, Shosha E, Fouda AY. Role of myeloid cells in ischemic retinopathies: recent advances and unanswered questions. J Neuroinflammation. 2024 Mar 07; 21(1):65. PMID: 38454477.
      View in: PubMed
    5. Shosha E, Shahror RA, Morris CA, Xu Z, Lucas R, McGee-Lawrence ME, Rusch NJ, Caldwell RB, Fouda AY. The arginase 1/ornithine decarboxylase pathway suppresses HDAC3 to ameliorate the myeloid cell inflammatory response: implications for retinal ischemic injury. Cell Death Dis. 2023 09 21; 14(9):621. PMID: 37735154.
      View in: PubMed
    6. Liu S, Wu J, Stolarz A, Zhang H, Boerma M, Byrum SD, Rusch NJ, Ding Z. PCSK9 attenuates efferocytosis in endothelial cells and promotes vascular aging. Theranostics. 2023; 13(9):2914-2929. PMID: 37284459.
      View in: PubMed
    7. Qi X, Rusch NJ, Fan J, Mora CJ, Xie L, Mu S, Rabinovitch PS, Zhang H. Mitochondrial proton leak in cardiac aging. Geroscience. 2023 08; 45(4):2135-2143. PMID: 36856945.
      View in: PubMed
    8. Stolarz AJ, Mu S, Zhang H, Fouda AY, Rusch NJ, Ding Z. Opinion: Endothelial Cells - Macrophage-Like Gatekeepers? Front Immunol. 2022; 13:902945. PMID: 35619719.
      View in: PubMed
    9. Pal S, Rahman J, Mu S, Rusch NJ, Stolarz AJ. Drug-Related Lymphedema: Mysteries, Mechanisms, and Potential Therapies. Front Pharmacol. 2022; 13:850586. PMID: 35308247.
      View in: PubMed
    10. Van S, Pal S, Garner BR, Steed K, Sridharan V, Mu S, Rusch NJ, Stolarz AJ. Dantrolene Prevents the Lymphostasis Caused by Doxorubicin in the Rat Mesenteric Circulation. Front Pharmacol. 2021; 12:727526. PMID: 34483938.
      View in: PubMed
    11. Garner BR, Stolarz AJ, Stuckey D, Sarimollaoglu M, Liu Y, Palade PT, Rusch NJ, Mu S. KATP Channel Openers Inhibit Lymphatic Contractions and Lymph Flow as a Possible Mechanism of Peripheral Edema. J Pharmacol Exp Ther. 2021 01; 376(1):40-50. PMID: 33100270.
      View in: PubMed
    12. Moore CL, Henry DS, McClenahan SJ, Ball KK, Rusch NJ, Rhee SW. Metoprolol Impairs ?1-Adrenergic Receptor-Mediated Vasodilation in Rat Cerebral Arteries: Implications for ?-Blocker Therapy. J Pharmacol Exp Ther. 2021 01; 376(1):127-135. PMID: 33100271.
      View in: PubMed
    13. Cozart MA, Phelan KD, Wu H, Mu S, Birnbaumer L, Rusch NJ, Zheng F. Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus. Sci Rep. 2020 01 21; 10(1):812. PMID: 31964991.
      View in: PubMed
    14. Shrum S, Rusch NJ, MacMillan-Crow LA. Specific BK Channel Activator NS11021 Protects Rat Renal Proximal Tubular Cells from Cold Storage-Induced Mitochondrial Injury In Vitro. Biomolecules. 2019 12 04; 9(12). PMID: 31817165.
      View in: PubMed
    15. Boulanger CM, Baretella O, Blaise G, Bond RA, Cai Y, Chan CKY, Chataigneau T, Chen MJ, Chen H, Cheng Y, Clement DL, Cohen RA, Collis M, Danser AHJ, de Mey J, Detremmerie CMS, Duprez D, Feletou M, Flavahan N, Gao Y, Guo Y, Hoeffner U, Houston DS, Huang IB, Huang Y, Iliano S, Junquero D, Katusic ZS, Komori K, Lee MYK, Leung SWS, Li Z, Liang SC, Liu JTC, Luscher TF, Michel F, Miller VM, Mombouli JV, Morrison K, Muldoon SM, O'Rourke S, Perrault L, Quignard JF, Rusch NJ, Sanchez-Ferrer CF, Schini-Kerth V, Shen K, Shi Y, Song E, Sun KWY, Taddei S, Tang EHC, Tuncer M, van den Ende R, Vedernikov Y, Verbeuren TJ, Webb C, Weigert A, Wong KHK, Xu C, Yang K, Ying F, Zellers T, Zhao Y, Zou Q, Shimokawa H. Tribute to Paul M. Vanhoutte, MD, PhD (1940-2019). Arterioscler Thromb Vasc Biol. 2019 12; 39(12):2445-2447. PMID: 31770032.
      View in: PubMed
    16. Zheng F, Mu S, Rusch NJ. Leptin Activates Trpm7 Channels in the Carotid Body As a Mechanism of Obesity-Related Hypertension. Circ Res. 2019 11 08; 125(11):1003-1005. PMID: 31697634.
      View in: PubMed
    17. Stolarz AJ, Sarimollaoglu M, Marecki JC, Fletcher TW, Galanzha EI, Rhee SW, Zharov VP, Klimberg VS, Rusch NJ. Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow. J Pharmacol Exp Ther. 2019 11; 371(2):278-289. PMID: 31439806.
      View in: PubMed
    18. Mu S, Fantegrossi WE, Rusch NJ. Cocaine-Responsive miRNA and Blood Pressure Elevation. Hypertension. 2018 04; 71(4):561-562. PMID: 29483229.
      View in: PubMed
    19. Sarimollaoglu M, Stolarz AJ, Nedosekin DA, Garner BR, Fletcher TW, Galanzha EI, Rusch NJ, Zharov VP. High-speed microscopy for in vivo monitoring of lymph dynamics. J Biophotonics. 2018 08; 11(8):e201700126. PMID: 29232054.
      View in: PubMed
    20. Rhee SW, Rusch NJ. Molecular determinants of beta-adrenergic signaling to voltage-gated K+ channels in the cerebral circulation. Microcirculation. 2018 01; 25(1). PMID: 29072364.
      View in: PubMed
    21. Hill BJF, Dalton RJ, Joseph BK, Thakali KM, Rusch NJ. 17?-estradiol reduces Cav 1.2 channel abundance and attenuates Ca2+ -dependent contractions in coronary arteries. Pharmacol Res Perspect. 2017 10; 5(5). PMID: 28971605.
      View in: PubMed
    22. Hilgers RH, Kundumani-Sridharan V, Subramani J, Chen LC, Cuello LG, Rusch NJ, Das KC. Thioredoxin reverses age-related hypertension by chronically improving vascular redox and restoring eNOS function. Sci Transl Med. 2017 02 08; 9(376). PMID: 28179506.
      View in: PubMed
    23. Detweiler ND, Song L, McClenahan SJ, Versluis RJ, Kharade SV, Kurten RC, Rhee SW, Rusch NJ. BK channels in rat and human pulmonary smooth muscle cells are BKa-?1 functional complexes lacking the oxygen-sensitive stress axis regulated exon insert. Pulm Circ. 2016 Dec; 6(4):563-575. PMID: 28090300.
      View in: PubMed
    24. Stolarz AJ, Rusch NJ. Gender Differences in Cardiovascular Drugs. Cardiovasc Drugs Ther. 2015 Aug; 29(4):403-10. PMID: 26227895.
      View in: PubMed
    25. Stimers JR, Song L, Rusch NJ, Rhee SW. Overexpression of the Large-Conductance, Ca2+-Activated K+ (BK) Channel Shortens Action Potential Duration in HL-1 Cardiomyocytes. PLoS One. 2015; 10(6):e0130588. PMID: 26091273.
      View in: PubMed
    26. Schleifenbaum J, Kassmann M, Szij?rt? IA, Hercule HC, Tano JY, Weinert S, Heidenreich M, Pathan AR, Anistan YM, Alenina N, Rusch NJ, Bader M, Jentsch TJ, Gollasch M. Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries. Circ Res. 2014 Jul 07; 115(2):263-72. PMID: 24838176.
      View in: PubMed
    27. Moore CL, Nelson PL, Parelkar NK, Rusch NJ, Rhee SW. Protein kinase A-phosphorylated KV1 channels in PSD95 signaling complex contribute to the resting membrane potential and diameter of cerebral arteries. Circ Res. 2014 Apr 11; 114(8):1258-67. PMID: 24585759.
      View in: PubMed
    28. Patton AL, Seely KA, Pulla S, Rusch NJ, Moran CL, Fantegrossi WE, Knight LD, Marraffa JM, Kennedy PD, James LP, Endres GW, Moran JH. Quantitative measurement of acetyl fentanyl and acetyl norfentanyl in human urine by LC-MS/MS. Anal Chem. 2014 Feb 04; 86(3):1760-6. PMID: 24354295.
      View in: PubMed
    29. Abou-Saleh H, Pathan AR, Daalis A, Hubrack S, Abou-Jassoum H, Al-Naeimi H, Rusch NJ, Machaca K. Inositol 1,4,5-trisphosphate (IP3) receptor up-regulation in hypertension is associated with sensitization of Ca2+ release and vascular smooth muscle contractility. J Biol Chem. 2013 Nov 15; 288(46):32941-51. PMID: 24097979.
      View in: PubMed
    30. Mercado CP, Quintero MV, Li Y, Singh P, Byrd AK, Talabnin K, Ishihara M, Azadi P, Rusch NJ, Kuberan B, Maroteaux L, Kilic F. A serotonin-induced N-glycan switch regulates platelet aggregation. Sci Rep. 2013 Sep 30; 3:2795. PMID: 24077408.
      View in: PubMed
    31. Nedosekin DA, Juralti MA, Sarimollaoglu M, Moore CL, Rusch NJ, Smeltzer MS, Zharov VP, Galazha EI. Photoacustic and photothermal detection of circulating tumor cells, bacteria and nanoparticles in cerebrospinal fluid in vivo and ex vivo. J Biophotonics. 2013; 6(6-7):523-33 (PMID: 23681943).
    32. Nedosekin DA, Juratli MA, Sarimollaoglu M, Moore CL, Rusch NJ, Smeltzer MS, Zharov VP, Galanzha EI. Photoacoustic and photothermal detection of circulating tumor cells, bacteria and nanoparticles in cerebrospinal fluid in vivo and ex vivo. J Biophotonics. 2013 Jun; 6(6-7):523-33. PMID: 23681943.
      View in: PubMed
    33. Singh P, Fletcher TW, Li Y, Rusch NJ, Kilic F. Serotonin uptake rates in platelets from angiotensin II-induced hypertensive mice. Health (Irvine Calif). 2013 Mar 01; 5(4A):31-39. PMID: 24163726.
      View in: PubMed
    34. Kharade SV, Sonkusare SK, Srivastava AK, Thakali KM, Fletcher TW, Rhee SW, Rusch NJ. The Beta 3 subunit contributes to vascular calcium channel upregulation and hypertension in angiotensin II-infused C57BL/6 mice. Hypertension. 2013; 61(1):137-42 (PMID: 23129698).
    35. Kharade SV, Sonkusare SK, Srivastava AK, Thakali KM, Fletcher TW, Rhee SW, Rusch NJ. The ?3 subunit contributes to vascular calcium channel upregulation and hypertension in angiotensin II-infused C57BL/6 mice. Hypertension. 2013 Jan; 61(1):137-42. PMID: 23129698.
      View in: PubMed
    36. Nguyen AT, Gomez D, Bell RD, Campbell JH, Clowes AW, Gabbiani G, Giachelli CM, Parmacek MS, Raines EW, Rusch NJ, Speer MY, Sturek M, Thyberg J, Towler DA, Weiser-Evans MC, Yan C, Miano JM, Owens GK. Smooth muscle cell plasticity: fact or fiction? Circ Res. 2013 Jan 04; 112(1):17-22. PMID: 23093573.
      View in: PubMed
    37. Hirenallur-S DK, Detweiler ND, Haworth ST, Leming JT, Gordon JB, Rusch NJ. Furegrelate, a thromboxane synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets. Pulm Circ. 2012 Apr-Jun; 2(2):193-200. PMID: 22837860.
      View in: PubMed
    38. Detweiler ND, Srivastava AK, Pathan AR, Kharade SV, Rusch NJ. Cell Physiology Source Book. Smooth muscle excitability. 2012.
    39. Hirenallur-S DK, Detweiler ND, Haworth ST, Leming JT, Gordon JB, Rusch NJ. Furegulate, a thromboxane synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets. Pulm Circ. 2012; 2(2):193-200 (PMID: 22837860).
    40. Joseph BK, Thakali KM, Pathan AR, Kang E, Rusch NJ, Rhee SW. Postsynaptic density-95 scaffolding of Shaker-type K? channels in smooth muscle cells regulates the diameter of cerebral arteries. J Physiol. 2011 Nov 01; 589(Pt 21):5143-52. PMID: 21911612.
      View in: PubMed
    41. Pathan AR, Rusch NJ. Two-pore domain K? channels: evidence for TWIK-2 in blood pressure regulation. Hypertension. 2011 Oct; 58(4):539-41. PMID: 21876073.
      View in: PubMed
    42. Thakali KM, Kharade SV, Sonkusare SK, Rhee SW, Stimers JR, Rusch NJ. Intracellular Ca2+ silences L-type Ca2+ channels in mesenteric veins: mechanism of venous smooth muscle resistance to calcium channel blockers. Circ Res. 2010 Mar 05; 106(4):739-47. PMID: 20044515.
      View in: PubMed
    43. Pang L, Rusch NJ. High-conductance, Ca(2+) -activated K+ channels: altered expression profiles in aging and cardiovascular disease. Mol Interv. 2009 Oct; 9(5):230-3. PMID: 19828830.
      View in: PubMed
    44. Rusch NJ. BK channels in cardiovascular disease: a complex story of channel dysregulation. Am J Physiol Heart Circ Physiol. 2009 Nov; 297(5):H1580-2. PMID: 19749161.
      View in: PubMed
    45. Tobin AA, Joseph BK, Al-Kindi HN, Albarwani S, Madden JA, Nemetz LT, Rusch NJ, Rhee SW. Loss of cerebrovascular Shaker-type K(+) channels: a shared vasodilator defect of genetic and renal hypertensive rats. Am J Physiol Heart Circ Physiol. 2009 Jul; 297(1):H293-303. PMID: 19411284.
      View in: PubMed
    46. Ahmed BA, Bukhari IA, Jeffus BC, Harney JT, Thyparambil S, Ziu E, Fraer M, Rusch NJ, Zimniak P, Lupashin V, Tang D, Kilic F. The cellular distribution of serotonin transporter is impeded on serotonin-altered vimentin network. PLoS One. 2009; 4(3):e4730. PMID: 19270731.
      View in: PubMed
    47. Tobin AA, Joseph BK, Albarwani S, Al-Kindi HN, Madden JA, Nemetz LT, Rusch NJ, Rhee SW. Loss of Shaker-type, voltage-gated K channels contributes to enhanced crebrovascular tome in hypertensive rats. 2009.
    48. Hirenallur-S DK, Haworth ST, Leming JT, Chang J, Hernandez G, Gordon JB, Rusch NJ. Upregulation of vascular calcium channels in neonatal piglets with hypoxia-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2008 Nov; 295(5):L915-24. PMID: 18776054.
      View in: PubMed
    49. Telemaque S, Sonkusare S, Grain T, Rhee S, Stimers JR, Rusch NJ, Marsh JD. Design of mutant beta subunits as decoy molecules to reduce the expression of function calcium channels in cardiac cells. J Pharm Experim Therap. 2008; 325(1):37-46 (PMID: 18184831).
    50. T?l?maque S, Sonkusare S, Grain T, Rhee SW, Stimers JR, Rusch NJ, Marsh JD. Design of mutant beta2 subunits as decoy molecules to reduce the expression of functional Ca2+ channels in cardiac cells. J Pharmacol Exp Ther. 2008 Apr; 325(1):37-46. PMID: 18184831.
      View in: PubMed
    51. Marsh JD, Telemaque S, Rhee SW, Stimers JR, Rusch NJ. Delivery of ion channel genes to treat cardiovascular diseases. Trans Am Clin Climatol Assoc. 2008; 119:171-82; discussion 182-3. PMID: 18596857.
      View in: PubMed
    52. Bryan RM, Joseph BK, Lloyd E, Rusch NJ. Starring TREK-1: the next generation of vascular K+ channels. Circ Res. 2007 Jul 20; 101(2):119-21. PMID: 17641234.
      View in: PubMed
    53. Joseph BK, Rhee SW, Hirenallur DK, Rusch NJ. New Frontiers in Smooth Muscle Biology and Physiology. Potassium channels in vascular smooth muscle: Structure, function and experimental interventions. 2007.
    54. Sonkusare S, Fraer M, Marsh JD, Rusch NJ. Disrupting calcium channel expression to lower blood pressure: new targeting of a well-known channel. Mol Interv. 2006 Dec; 6(6):304-10. PMID: 17200457.
      View in: PubMed
    55. Sonkusare S, Palade PT, Marsh JD, Telemaque S, Pesic A, Rusch NJ. Vascular calcium channels and high blood pressure: pathophysiology and therapeutic implications. Vascul Pharmacol. 2006 Mar; 44(3):131-42. PMID: 16427812.
      View in: PubMed
    56. Beech DJ, Cheong A, Rusch NJ. Regulation of arterial tone by KV1 potassium channels. Circ Res. 2005 Apr 01; 96(6):e58. PMID: 15802615.
      View in: PubMed
    57. Rademacher DJ, Patel S, Ho WS, Savoie AM, Rusch NJ, Gauthier KM, Hillard CJ. U-46619 but not serotonin increases endocannabinoid content in middle cerebral artery: evidence for functional relevance. Am J Physiol Heart Circ Physiol. 2005 Jun; 288(6):H2694-701. PMID: 15695564.
      View in: PubMed
    58. Rusch NJ. Regulation of arterial tone by Kv1 potassium channels. 2005.
    59. Archer SL, Rusch NJ. Lung Biology in Health and Disease: Ion Channels in the Pulmonary Vasculature. Ion channel heterogeneity in the pulmonary vascular bed. 2005.
    60. Li H, Gutterman DD, Rusch NJ, Bubolz A, Liu Y. Nitration and functional loss of voltage-gated K+ channels in rat coronary microvessels exposed to high glucose. Diabetes. 2004 Sep; 53(9):2436-42. PMID: 15331556.
      View in: PubMed
    61. Pesic A, Madden JA, Pesic M, Rusch NJ. High blood pressure upregulates arterial L-type Ca2+ channels: is membrane depolarization the signal? Circ Res. 2004 May 28; 94(10):e97-104. PMID: 15131006.
      View in: PubMed
    62. Albarwani S, Nemetz LT, Madden JA, Tobin AA, England SK, Pratt PF, Rusch NJ. Voltage-gated K+ channels in rat small cerebral arteries: molecular identity of the functional channels. J Physiol. 2003 Sep 15; 551(Pt 3):751-63. PMID: 12815189.
      View in: PubMed
    63. Gauthier KG, Rusch NJ. EDHF 2002. Potassium channels and membrane potential in vascular smooth endothelial and smooth muscle cells. 2003.
    64. Gauthier KM, Liu C, Popovic A, Albarwani S, Rusch NJ. Freshly isolated bovine coronary endothelial cells do not express the BK Ca channel gene. J Physiol. 2002 12 15; 545(3):829-36. PMID: 12482889.
      View in: PubMed
    65. Molero MM, Giulumian AD, Reddy VB, Ludwig LM, Pollock JS, Pollock DM, Rusch NJ, Fuchs LC. Decreased endothelin binding and [Ca2+]i signaling in microvessels of DOCA-salt hypertensive rats. J Hypertens. 2002 Sep; 20(9):1799-805. PMID: 12195122.
      View in: PubMed
    66. Pratt PF, Bonnet S, Ludwig LM, Bonnet P, Rusch NJ. Upregulation of L-type Ca2+ channels in mesenteric and skeletal arteries of SHR. Hypertension. 2002 Aug; 40(2):214-9. PMID: 12154116.
      View in: PubMed
    67. Cox RH, Rusch NJ. New expression profiles of voltage-gated ion channels in arteries exposed to high blood pressure. Microcirculation. 2002; 9(4):243-57. PMID: 12152102.
      View in: PubMed
    68. Rusch NJ, Lombard JH. Physiology Secrets. Cell transport, nerves and muscle. 2002.
    69. Cox RH, Rusch NJ. Microcirculation. New expression profiles of voltage-gated ion channels in vasculat smooth muscle cells exposed to high blood pressure. 2002.
    70. Hermsmeyer KH, Rusch NJ. Cell Physiology Source Book. Smooth muscle action potentials and electrical profiles. 2001.
    71. Koch RO, Trieb M, Koschak A, Wanner SG, Gauthier KM, Rusch NJ, Knaus H-G. Potassium Channels in Cardiovascular Biology. Design and use of antibodies for mapping K+ channel expression in the cardiovascular system. 2001.
    72. Gauthier KM, Rusch NJ. Rat Coronary Endothelial Cell Membrane Potential Responses During Hypertension. Hypertension. 2001; 37(1):66 - 71 (PMID: 11208758).
    73. Berger MG, Rusch NJ. Potassium Channels in Cardiovascular Biology. Overexpression of Ca2+-sensitive K+ channels in arterial muscle membranes during systemic hypertension. 2001.
    74. Gauthier-Rein KM, Rusch NJ. Impaired endothelial signaling and dilator mechanisms in small coronary arteries from renal hypertensive rats. 2001; 37:66-71.
    75. Madden J, Rusch NJ. Heart Physiology and Pathophysiology. Electrical properties of vascular smooth muscle. 2001.
    76. Gauthier KM, Rusch NJ. Rat Coronary Endothelial Cell Membrane Potential Responses During Hypertension. Hypertension. 2001 Jan; 37(1):66-71. PMID: 11208758.
      View in: PubMed
    77. Berger MG, Rusch NJ. Perspectives in Drug Discovery. Voltage and calcium-gated potassium channels: functional expression and therapeutic potential in the vasculature. 2000.
    78. Rusch NJ, Lombard JH. Physiology Secrets. Cell transport, nerves and muscle. 1998; 1.
    79. Berger M, Vandier C, Jackson WF, Bonnet P, Rusch NJ. Differential regulation by intracellular acidosis of K+ current in coronary and pulmonary vascular smooth muscle cells. 1998; 44:H1351-H1359.
    80. Rusch NJ, Liu Y. Invited Review: K+ channels in hypertension: homeostatic pathways to buffer arterial contraction. Journal of Laboratory and Clinical Medicine. 1997; 130:245-251.
    81. Jackson WF, Rusch NJ. Voltage-activated and ATP-sensitive K+ channels regulate resting membrane potential in cremasteric arteriolar muscle cells. 1996; 909-913.
    82. Rusch NJ, Wooldridge TA, Kulig C, Almassi GH, Olinger GN, Boerboom LE. Activation of human saphenous veins at arterial distending pressures. 1995; 110:1005-1012.
    83. Li P, Zou A, Al-Kayed NJ, Rusch NJ, Harder DR. GTP-binding proteins in aortic smooth muscle from experimentally-induced hypertensive rats. 1994; 23:914-918.
    84. Rusch NJ, Runnels AM. Correlation of blood pressure and K+ channel current density in aortic muscle membranes of hypertensive rats. 1994; 23:941-945.
    85. Sanchez AM, Woolridge TA, Boerboom LE, Almassi GH, Olinger GN, Rusch NJ. Relaxation of canine saphenous veins during storage in Plasma-Lyte and normal saline solution. 1994; 107:1445-1453.
    86. Rusch NJ, Hermsmeyer K. Handbook on Ionic Transport in Hypertension: New Perspectives. Calcium channels in hypertension. 1994.
    87. Rusch NJ, Kotchen TA. Handbook of Hypertension. Vascular muscle regulation by calcium, potassium and magnesium in hypertension. 1994.
    88. Rusch NJ, England SK, Hermsmeyer K. Physiology and Pathophysiology of the Heart. Properties of vascular smooth muscle in hypertension. 1994; 53.
    89. Eskinder H, Rusch NJ, Bosnjak ZJ. Theeffects of halothane, enflurane and isoflurane on T-type and L-type calcium currents in single canine Purkinje cells. 1991; 74:919-926.
    90. Rusch NJ, Stekiel WJ. Cellular and Molecular Mechanisms in Hypertension: Implications for Pathogenesis and Treatments. Ionic channels of vascular muscle in hypertension. 1991.
    91. Hermsmeyer K, Rusch NJ. Essential Hypertension. Membrane potential and calcium influx in vascular muscle from spontaneously hypertensive rats. 1989.
    92. Rusch NJ, Hermsmeyer K. Whole-cell calcium current in isolated vascular smooth muscle cells. 1988; 80:87-93.
    93. Chyatte D, Rusch NJ, Sundt TM. Prevention of chronic vasospasm using ibuprofen and high dose methylprednisolone. 1983; 59:925-932.
    94. Thakali KM, Pathan AR, Kharade SV, Rusch NJ. Muscle. Potassium, sodium and chloride channel in arterial smooth muscle cells.
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