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Daisy Alapat

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPathology, College of Medicine
DivisionPathology Clinical
AddressB.023 Hospital (new hospital)
4200 Shuffield.
Mail Slot # 502
Little Rock AR 72205
Phone501-686-8870
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Fajgenbaum DC, Pierson SK, Kanhai K, Bagg A, Alapat D, Lim MS, Lechowicz MJ, Srkalovic G, Uldrick TS, van Rhee F. The disease course of Castleman disease patients with fatal outcomes in the ACCELERATE registry. Br J Haematol. 2022 07; 198(2):307-316. PMID: 35507638.
      View in: PubMed
    2. Mohan M, Gundarlapalli S, Szabo A, Yarlagadda N, Kakadia S, Konda M, Jillella A, Fnu A, Ogunsesan Y, Yarlagadda L, Thalambedu N, Munawar H, Graziutti M, Al Hadidi S, Alapat D, Thanendrarajan S, Zangari M, van Rhee F, Schinke C. Tandem autologous stem cell transplantation in patients with persistent bone marrow minimal residual disease after first transplantation in multiple myeloma. Am J Hematol. 2022 06 01; 97(6):E195-E198. PMID: 35285981.
      View in: PubMed
    3. Mohan M, Kendrick S, Szabo A, Yarlagadda N, Atwal D, Pandey Y, Roy A, Parikh R, Lopez J, Thanendrarajan S, Schinke C, Alapat D, Sawyer J, Tian E, Tricot G, van Rhee F, Zangari M. Clinical implications of loss of bone marrow minimal residual disease negativity in multiple myeloma. Blood Adv. 2022 02 08; 6(3):808-817. PMID: 34807986.
      View in: PubMed
    4. Baker D, Bimali M, Carrillo L, Sachedina A, Alapat D, Hoque MS, Kottarathara M, Parikh R, Erra A, Mitma AA, Mathur P, Ogunsesan Y, Yarlagadda L, Gundarlapalli S, Thanendrarajan S, Zangari M, Van Rhee F, Tricot G, Schinke C. Predicting risk of progression in relapsed multiple myeloma using traditional risk models, focal lesion assessment with PET-CT and minimal residual disease status. Haematologica. 2021 12 01; 106(12):3215-3218. PMID: 34847659.
      View in: PubMed
    5. Baker D, Bimali M, Carrillo L, Sachedina A, Alapat D, Hoque MS, Kottarathara M, Parikh R, Erra A, Mitma AA, Mathur P, Ogunsesan Y, Yarlagadda L, Gundarlapalli S, Thanendrarajan S, Zangari M, Van Rhee F, Tricot G, Schinke C. Predicting risk of progression in relapsed multiple myeloma using traditional risk models, focal lesion assessment with PET-CT and minimal residual disease status. Haematologica. 2021 08 12. PMID: 34382384.
      View in: PubMed
    6. Mohan M, Meek JC, Meek ME, Broadwater R, Alapat D, van Rhee F. Combinatorial treatment for unresectable unicentric Castleman disease. Eur J Haematol. 2021 Oct; 107(4):484-488. PMID: 34242421.
      View in: PubMed
    7. Mohan M, Szabo A, Yarlagadda N, Gundarlapalli S, Thanendrarajan S, Kendrick S, Schinke C, Alapat D, Sawyer J, Tian E, Tricot G, van Rhee F, Zangari M. Persistent bone marrow minimal residual disease as a "high-risk" disease feature in multiple myeloma. Am J Hematol. 2021 09 01; 96(9):E341-E344. PMID: 34050985.
      View in: PubMed
    8. Danziger SA, McConnell M, Gockley J, Young MH, Rosenthal A, Schmitz F, Reiss DJ, Farmer P, Alapat DV, Singh A, Ashby C, Bauer M, Ren Y, Smith K, Couto SS, van Rhee F, Davies F, Zangari M, Petty N, Orlowski RZ, Dhodapkar MV, Copeland WB, Fox B, Hoering A, Fitch A, Newhall K, Barlogie B, Trotter MWB, Hershberg RM, Walker BA, Dervan AP, Ratushny AV, Morgan GJ. Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials. PLoS Med. 2020 11; 17(11):e1003323. PMID: 33147277.
      View in: PubMed
    9. Wyeth A, Gokden N, Alapat D, Zangari M, Pina-Oviedo S. Primary Plasma Cell Neoplasm of the Kidney Without Formation of a Mass and Its Renal Manifestations: An Interstitial Variant of Renal Plasmacytoma? Clin Lymphoma Myeloma Leuk. 2020 09; 20(9):e551-e555. PMID: 32576503.
      View in: PubMed
    10. Sridharan A, Schinke CD, Georgiev G, Da Silva Ferreira M, Thiruthuvanathan V, MacArthur I, Bhagat TD, Choudhary GS, Aluri S, Chen J, Pradhan K, Xia Y, Panjikaran M, Sims G, Bhagat CK, Bender R, Keeler L, Graber A, Heuck C, Fletcher FA, Alapat D, Weinhold N, Johnson SK, Wickrema A, Barlogie B, Morgan GJ, Shastri A, Steidl U, Will B, Verma A. Stem cell mutations can be detected in myeloma patients years before onset of secondary leukemias. Blood Adv. 2019 12 10; 3(23):3962-3967. PMID: 31805192.
      View in: PubMed
    11. Abdallah AA, Alapat D, Kaur V, Atrash S. Outcomes of autologous stem cell transplant for cardiac AL-amyloidosis and cardiac light chain deposition disease. J Oncol Pharm Pract. 2020 Jul; 26(5):1128-1133. PMID: 31795821.
      View in: PubMed
    12. Nabel CS, Sameroff S, Shilling D, Alapat D, Ruth JR, Kawano M, Sato Y, Stone K, Spetalen S, Valdivieso F, Feldman MD, Chadburn A, Fosså A, van Rhee F, Lipkin WI, Fajgenbaum DC. Virome capture sequencing does not identify active viral infection in unicentric and idiopathic multicentric Castleman disease. PLoS One. 2019; 14(6):e0218660. PMID: 31242229.
      View in: PubMed
    13. Alapat D. Cytoplasmic Immunoglobulin Vs. DNA Analysis by Flow Cytometry. Methods Mol Biol. 2018; 1792:35-45. PMID: 29797250.
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    14. Mathur P, Alapat D, Kumar M, Thanendrarajan S. Metastatic prostate cancer with bone marrow infiltration mimicking multiple myeloma. Clin Case Rep. 2018 02; 6(2):269-273. PMID: 29445461.
      View in: PubMed
    15. Kaur V, Swami A, Alapat D, Abdallah AO, Motwani P, Hutchins LF, Jethava Y. Clinical characteristics, molecular profile and outcomes of myeloid sarcoma: a single institution experience over 13 years. Hematology. 2018 Jan; 23(1):17-24. PMID: 28574302.
      View in: PubMed
    16. Thanendrarajan S, Tian E, Qu P, Mathur P, Schinke C, van Rhee F, Zangari M, Rasche L, Weinhold N, Alapat D, Bellamy W, Ashby C, Mattox S, Epstein J, Yaccoby S, Barlogie B, Hoering A, Bauer M, Walker BA, Davies FE, Morgan GJ. The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma. Haematologica. 2017 09; 102(9):e364-e367. PMID: 28550191.
      View in: PubMed
    17. Schinke C, Hoering A, Wang H, Carlton V, Thanandrarajan S, Deshpande S, Patel P, Molnar G, Susanibar S, Mohan M, Mathur P, Radhakrishnan M, Hoque S, Jo Kamimoto J, Grazziutti M, van Rhee F, Zangari M, Insuasti-Beltran G, Alapat D, Post G, Yaccoby S, Epstein J, Rasche L, Johnson S, Moorhead M, Willis T, Barlogie B, Walker B, Weinhold N, Davies FE, Morgan GJ. The prognostic value of the depth of response in multiple myeloma depends on the time of assessment, risk status and molecular subtype. Haematologica. 2017 08; 102(8):e313-e316. PMID: 28522572.
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    18. Susanibar-Adaniya S, Mathur P, Henrich Lobo R, Alapat D, Kumar M, Heuck C, Thanendrarajan S. Nasopharyngeal amyloidoma with osteolytic lesions leading to diagnosis of systemic light-chain amyloidosis. Clin Case Rep. 2017 06; 5(6):812-815. PMID: 28588817.
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    19. Jethava Y, Mitchell A, Zangari M, Waheed S, Schinke C, Thanendrarajan S, Sawyer J, Alapat D, Tian E, Stein C, Khan R, Heuck CJ, Petty N, Avery D, Steward D, Smith R, Bailey C, Epstein J, Yaccoby S, Hoering A, Crowley J, Morgan G, Barlogie B, van Rhee F. Dose-dense and less dose-intense total therapy 5 for gene expression profiling-defined high-risk multiple myeloma. Blood Cancer J. 2016 09 16; 6:e471. PMID: 27635734.
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    20. Jethava Y, Mitchell A, Zangari M, Waheed S, Schinke C, Thanendrarajan S, Sawyer J, Alapat D, Tian E, Stein C, Khan R, Heuck CJ, Petty N, Avery D, Steward D, Smith R, Bailey C, Epstein J, Yaccoby S, Hoering A, Crowley J, Morgan G, Barlogie B, van Rhee F. Dose-dense and less dose-intense Total Therapy 5 for gene expression profiling-defined high-risk multiple myeloma. Blood Cancer J. 2016 07 29; 6(7):e453. PMID: 27471869.
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    21. Boota M, Schinke C, Ledoux S, Alapat D, Khan R, Barlogie B. CA-125 secreting IgG kappa multiple myeloma. Am J Hematol. 2016 Oct; 91(10):E457-8. PMID: 27340819.
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    22. Krishna Joshia, Kevin Kuriakosea, Rahul Ravillaa, Yogita Rochlania, Anwar Rjoopb, Daisy Alapatb, AppalaNaidu Sasapua, . Epstein-Barr Virus-Induced Polymorphic Nodal Lymphoproliferative Disorder Presenting as Recurrent Fever and Scrotal Swelling: A Case Report and Review of Literature. Journal of Medical Cases. 2016; 7(8):354-357 .
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    23. Fulton E, Alapat D, Mabry A, Gao L, Shalin SC. CLL/SLL with initial presentation as a longstanding cutaneous plaque: a rare case. J Cutan Pathol. 2016 Aug; 43(8):717-21. PMID: 27147484.
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    24. Papanikolaou X, Rosenthal A, Dhodapkar M, Epstein J, Khan R, van Rhee F, Jethava Y, Waheed S, Zangari M, Hoering A, Crowley J, Alapat D, Davies F, Morgan G, Barlogie B. Flow cytometry defined cytoplasmic immunoglobulin index is a major prognostic factor for progression of asymptomatic monoclonal gammopathies to multiple myeloma (subset analysis of SWOG S0120). Blood Cancer J. 2016 Mar 25; 6:e410. PMID: 27015287.
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    25. Amy J. Powless ; Lauren E. Feekin ; Joshua A. Hutcheson ; Daisy V. Alapat and Timothy J. Muldoon . Proc. SPIE 9715, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics, 97150A (March 4, 2016); doi:10.1117/12.2213267. Low-cost computing and network communication for a point-of-care device to perform a 3-part leukocyte differential. 2016.
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    26. Ravilla R, Joiner AK, Alapat D, Arnaoutakis K. An Unusual Case of Acute Promyelocytic Leukemia Presenting With Hypoplastic Bone Marrow and Pancytopenia. Am J Med Sci. 2016 Mar; 351(3):317-8. PMID: 26992265.
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    27. Bhutani M, Shahid Z, Schnebelen A, Alapat D, Usmani SZ. Cutaneous manifestations of multiple myeloma and other plasma cell proliferative disorders. Semin Oncol. 2016 06; 43(3):395-400. PMID: 27178694.
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    28. Jiwani S, Bornhost J, Alapat D. Biphenotypic plasma cell myeloma: two cases of plasma cell neoplasm with a coexpression of kappa and lambda light chains. Int J Clin Exp Pathol. 2015; 8(7):8536-44. PMID: 26339430.
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    29. Papanikolaou X, Alapat D, Rosenthal A, Stein C, Epstein J, Owens R, Yaccoby S, Johnson S, Bailey C, Heuck C, Tian E, Joiner A, van Rhee F, Khan R, Zangari M, Jethava Y, Waheed S, Davies F, Morgan G, Barlogie B. The flow cytometry-defined light chain cytoplasmic immunoglobulin index and an associated 12-gene expression signature are independent prognostic factors in multiple myeloma. Leukemia. 2015 Aug; 29(8):1713-20. PMID: 25753926.
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    30. Singh ZN, Jethava Y, Post GR, Alapat D, Sawyer J, Waheed S, Nair B, Usmani SZ, Bailey C, Petty N, Van Rhee F, Barlogie B. Fulminant onset of acute leukemia from normal hematopoiesis within 3 months of follow up for multiple myeloma treated with total therapy protocols. Clin Case Rep. 2015 Mar; 3(3):183-92. PMID: 25838910.
      View in: PubMed
    31. Alapat DV, Ramos JM, Anderson J, Post GR. The utility of B-cell receptor gene rearrangement studies in diagnosing diffuse large B-cell lymphoma with plasmacytic differentiation. Ann Clin Lab Sci. 2015; 45(1):79-82. PMID: 25696015.
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    32. Guru Murthy GS, Sawyer J, Alapat D, Samant R, Barlogie B. Strange bedfellows: mitotically active chronic myeloid leukemia in molecular complete remission, detected in focal lesion of myeloma. Clin Lymphoma Myeloma Leuk. 2014 Aug; 14(4):e127-9. PMID: 24685577.
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    33. Dholaria B, Alapat D, Arnaoutakis K. Primary bone marrow Hodgkin lymphoma in an HIV-negative patient. Int J Hematol. 2014 Apr; 99(4):503-7. PMID: 24532438.
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    34. Liu YC, Reddi HV, Waheed S, Alapat D, Highsmith WE, Edmondson RD, Barlogie B, van Rhee F. A compound T60A and V122I heterozygosity in the transthyretin gene causing early onset severe cardiac amyloidosis. Amyloid. 2014 Jun; 21(2):134-5. PMID: 24517438.
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    35. Katragadda L, Shahid Z, Restrepo A, Muzaffar J, Alapat D, Anaissie E. Preemptive intravenous immunoglobulin allows safe and timely administration of antineoplastic therapies in patients with multiple myeloma and parvovirus B19 disease. Transpl Infect Dis. 2013 Aug; 15(4):354-60. PMID: 23578205.
      View in: PubMed
    36. Pandey S, Post SR, Alapat DV, Smock KJ, Post GR. Prolonged prothrombin time correlates with serum monoclonal protein concentration in patients with plasma cell dyscrasia. Int J Lab Hematol. 2013 Aug; 35(4):421-7. PMID: 23217011.
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    37. Post GR, James L, Alapat D, Guillory V, Cottler-Fox M, Nakagawa M. A case of acquired dysfibrinogenemia in multiple myeloma treated with therapeutic plasma exchange. Transfus Apher Sci. 2013 Feb; 48(1):35-8. PMID: 22842111.
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    38. Dholaria B, Alapat D, Pandey T, Agarwal A. Plasmablastic lymphoma of the retroperitoneum in an HIV- and HCV-positive patient: hard to diagnose and harder to treat. Med Oncol. 2012 Dec; 29(5):3529-34. PMID: 22562157.
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    39. Alapat D, Coviello-Malle J, Owens R, Qu P, Barlogie B, Shaughnessy JD, Lorsbach RB. Diagnostic usefulness and prognostic impact of CD200 expression in lymphoid malignancies and plasma cell myeloma. Am J Clin Pathol. 2012 Jan; 137(1):93-100. PMID: 22180482.
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    40. Hage CA, Ribes JA, Wengenack NL, Baddour LM, Assi M, McKinsey DS, Hammoud K, Alapat D, Babady NE, Parker M, Fuller D, Noor A, Davis TE, Rodgers M, Connolly PA, El Haddad B, Wheat LJ. A multicenter evaluation of tests for diagnosis of histoplasmosis. Clin Infect Dis. 2011 Sep; 53(5):448-54. PMID: 21810734.
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    41. E. Mireles-Cabodevila1, N. K. Meena1, J. M. Coviello-Malle1, D. Alapat1, Z. N. Singh. . Hemophagocytic Syndrome In Adults: Do The Diagnostic Criteria Apply To The Critically Ill Adult. 2011.
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    42. Alapat DV, Ain KB, Sloan DA, Monaghan KG, Karabakhtsian RG. Disparity between tissue and serum calcitonin and carcinoembryonic antigen in a patient with medullary thyroid carcinoma. Endocrine. 2011 Apr; 39(2):148-52. PMID: 21243446.
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    43. Bierenbaum J, Alapat DV, Godinez C, Park AE, Zhao XF, Baer MR. Littoral cell angioma: a correctable cause of progressive pancytopenia in a patient with myelodysplastic syndrome. Leuk Res. 2010 Apr; 34(4):e117-9. PMID: 19853914.
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    44. Alapat DV, Chaudhry T, Ardakany-Taghavi R, Kohtz DS. Fiber-types of sarcomeric proteins expressed in cultured myogenic cells are modulated by the dose of myogenin activity. Cell Signal. 2009 Jan; 21(1):128-35. PMID: 18955131.
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    45. Brandon JA, Jennings CD, Perez J, Caywood B, Alapat D, Kaplan AM, Bryson JS. Induction of murine syngeneic graft-versus-host disease by cells of recipient origin. Transplantation. 2007 Jun 27; 83(12):1620-7. PMID: 17589346.
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    46. Jacob T, Ascher E, Alapat D, Olevskaia Y, Hingorani A. Activation of p38MAPK signaling cascade in a VSMC injury model: role of p38MAPK inhibitors in limiting VSMC proliferation. Eur J Vasc Endovasc Surg. 2005 May; 29(5):470-8. PMID: 15966085.
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    47. Good PF, Alapat D, Hsu A, Chu C, Perl D, Wen X, Burstein DE, Kohtz DS. A role for semaphorin 3A signaling in the degeneration of hippocampal neurons during Alzheimer's disease. J Neurochem. 2004 Nov; 91(3):716-36. PMID: 15485501.
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    48. Chu C, Alapat D, Wen X, Timo K, Burstein D, Lisanti M, Shears S, Kohtz DS. Ectopic expression of murine diphosphoinositol polyphosphate phosphohydrolase 1 attenuates signaling through the ERK1/2 pathway. Cell Signal. 2004 Sep; 16(9):1045-59. PMID: 15212765.
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