 Glutamic Acid
"Glutamic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
| Descriptor ID |
D018698
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| MeSH Number(s) |
D12.125.067.750 D12.125.119.450 D12.125.427.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glutamic Acid".
Below are MeSH descriptors whose meaning is more specific than "Glutamic Acid".
This graph shows the total number of publications written about "Glutamic Acid" by people in UAMS Profiles by year, and whether "Glutamic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2020 | 0 | 4 | 4 | | 2018 | 1 | 0 | 1 | | 2017 | 2 | 3 | 5 | | 2016 | 1 | 1 | 2 | | 2014 | 3 | 3 | 6 | | 2013 | 1 | 0 | 1 | | 2012 | 3 | 1 | 4 | | 2011 | 2 | 3 | 5 | | 2010 | 2 | 1 | 3 | | 2009 | 5 | 1 | 6 | | 2008 | 3 | 3 | 6 | | 2007 | 2 | 3 | 5 | | 2006 | 5 | 4 | 9 | | 2005 | 6 | 3 | 9 | | 2004 | 3 | 1 | 4 | | 2002 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2000 | 3 | 1 | 4 | | 1999 | 1 | 2 | 3 | | 1998 | 1 | 1 | 2 | | 1997 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1994 | 0 | 3 | 3 | | 1993 | 0 | 3 | 3 | | 1992 | 0 | 3 | 3 | | 1991 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Glutamic Acid" by people in Profiles over the past ten years.
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Rothman DL, Dienel GA, Behar KL, Hyder F, DiNuzzo M, Giove F, Mangia S. Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission. J Cereb Blood Flow Metab. 2022 05; 42(5):844-860.
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Park GH, Noh H, Shao Z, Ni P, Qin Y, Liu D, Beaudreault CP, Park JS, Abani CP, Park JM, Le DT, Gonzalez SZ, Guan Y, Cohen BM, McPhie DL, Coyle JT, Lanz TA, Xi HS, Yin C, Huang W, Kim HY, Chung S. Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia. Nat Neurosci. 2020 11; 23(11):1352-1364.
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Dienel GA, Rothman DL. Reevaluation of Astrocyte-Neuron Energy Metabolism with Astrocyte Volume Fraction Correction: Impact on Cellular Glucose Oxidation Rates, Glutamate-Glutamine Cycle Energetics, Glycogen Levels and Utilization Rates vs. Exercising Muscle, and Na+/K+ Pumping Rates. Neurochem Res. 2020 Nov; 45(11):2607-2630.
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Rajani V, Sengar AS, Salter MW. Tripartite signalling by NMDA receptors. Mol Brain. 2020 02 18; 13(1):23.
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Blackburn PR, Sullivan AE, Gerassimou AG, Kleinendorst L, Bersten DC, Cooiman M, Harris KG, Wierenga KJ, Klee EW, van Gerpen JA, Ross OA, van Haelst MM, Whitelaw ML, Caulfield TR, Atwal PS. Functional Analysis of the SIM1 Variant p.G715V in 2 Patients With Obesity. J Clin Endocrinol Metab. 2020 01 01; 105(1).
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Fantegrossi WE, Wilson CD, Berquist MD. Pro-psychotic effects of synthetic cannabinoids: interactions with central dopamine, serotonin, and glutamate systems. Drug Metab Rev. 2018 Feb; 50(1):65-73.
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Dienel GA, Behar KL, Rothman DL. Cellular Origin of [18F]FDG-PET Imaging Signals During Ceftriaxone-Stimulated Glutamate Uptake: Astrocytes and Neurons. Neuroscientist. 2018 08; 24(4):316-328.
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Küry S, van Woerden GM, Besnard T, Proietti Onori M, Latypova X, Towne MC, Cho MT, Prescott TE, Ploeg MA, Sanders S, Stessman HAF, Pujol A, Distel B, Robak LA, Bernstein JA, Denommé-Pichon AS, Lesca G, Sellars EA, Berg J, Carré W, Busk ØL, van Bon BWM, Waugh JL, Deardorff M, Hoganson GE, Bosanko KB, Johnson DS, Dabir T, Holla ØL, Sarkar A, Tveten K, de Bellescize J, Braathen GJ, Terhal PA, Grange DK, van Haeringen A, Lam C, Mirzaa G, Burton J, Bhoj EJ, Douglas J, Santani AB, Nesbitt AI, Helbig KL, Andrews MV, Begtrup A, Tang S, van Gassen KLI, Juusola J, Foss K, Enns GM, Moog U, Hinderhofer K, Paramasivam N, Lincoln S, Kusako BH, Lindenbaum P, Charpentier E, Nowak CB, Cherot E, Simonet T, Ruivenkamp CAL, Hahn S, Brownstein CA, Xia F, Schmitt S, Deb W, Bonneau D, Nizon M, Quinquis D, Chelly J, Rudolf G, Sanlaville D, Parent P, Gilbert-Dussardier B, Toutain A, Sutton VR, Thies J, Peart-Vissers LELM, Boisseau P, Vincent M, Grabrucker AM, Dubourg C, Tan WH, Verbeek NE, Granzow M, Santen GWE, Shendure J, Isidor B, Pasquier L, Redon R, Yang Y, State MW, Kleefstra T, Cogné B, Petrovski S, Retterer K, Eichler EE, Rosenfeld JA, Agrawal PB, Bézieau S, Odent S, Elgersma Y, Mercier S. De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability. Am J Hum Genet. 2017 Nov 02; 101(5):768-788.
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Floruta CM, Du R, Kang H, Stein JL, Weick JP. Default Patterning Produces Pan-cortical Glutamatergic and CGE/LGE-like GABAergic Neurons from Human Pluripotent Stem Cells. Stem Cell Reports. 2017 11 14; 9(5):1463-1476.
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Sayin VI, LeBoeuf SE, Singh SX, Davidson SM, Biancur D, Guzelhan BS, Alvarez SW, Wu WL, Karakousi TR, Zavitsanou AM, Ubriaco J, Muir A, Karagiannis D, Morris PJ, Thomas CJ, Possemato R, Vander Heiden MG, Papagiannakopoulos T. Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer. Elife. 2017 10 02; 6.
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Kim SY, Kaufman MJ, Cohen BM, Jensen JE, Coyle JT, Du F, Öngür D. In Vivo Brain Glycine and Glutamate Concentrations in Patients With First-Episode Psychosis Measured by Echo Time-Averaged Proton Magnetic Resonance Spectroscopy at 4T. Biol Psychiatry. 2018 03 15; 83(6):484-491.
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Pinheiro BS, Lemos C, Neutzling Kaufmann F, Marques JM, da Silva-Santos CS, Carvalho E, Mackie K, Rodrigues RJ, Cunha RA, Köfalvi A. Hierarchical glucocorticoid-endocannabinoid interplay regulates the activation of the nucleus accumbens by insulin. Brain Res Bull. 2016 06; 124:222-30.
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Suva LJ, Gaddy D. Back to the Future: Evaluation of the Role of Glutamate in Bone Cells. Calcif Tissue Int. 2016 08; 99(2):112-3.
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Sacktor N, Miyahara S, Evans S, Schifitto G, Cohen B, Haughey N, Drewes JL, Graham D, Zink MC, Anderson C, Nath A, Pardo CA, McCarthy S, Hosey L, Clifford D. Impact of minocycline on cerebrospinal fluid markers of oxidative stress, neuronal injury, and inflammation in HIV-seropositive individuals with cognitive impairment. J Neurovirol. 2014 Dec; 20(6):620-6.
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Dienel GA. Lactate shuttling and lactate use as fuel after traumatic brain injury: metabolic considerations. J Cereb Blood Flow Metab. 2014 Nov; 34(11):1736-48.
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Dienel GA, McKenna MC. A dogma-breaking concept: glutamate oxidation in astrocytes is the source of lactate during aerobic glycolysis in resting subjects. J Neurochem. 2014 Nov; 131(4):395-8.
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Smith KL, John CS, Sypek EI, Ongür D, Cohen BM, Barry SM, Bechtholt AJ. Exploring the role of central astrocytic glutamate uptake in ethanol reward in mice. Alcohol Clin Exp Res. 2014 May; 38(5):1307-14.
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Duncan LE, Holmans PA, Lee PH, O'Dushlaine CT, Kirby AW, Smoller JW, Öngür D, Cohen BM. Pathway analyses implicate glial cells in schizophrenia. PLoS One. 2014; 9(2):e89441.
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Dienel GA, Cruz NF. Contributions of glycogen to astrocytic energetics during brain activation. Metab Brain Dis. 2015 Feb; 30(1):281-98.
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Dienel GA. Astrocytic energetics during excitatory neurotransmission: What are contributions of glutamate oxidation and glycolysis? Neurochem Int. 2013 Oct; 63(4):244-58.
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