 Proton Pump Inhibitors
"Proton Pump Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit H(+)-K(+)-EXCHANGING ATPASE. They are used as ANTI-ULCER AGENTS and sometimes in place of HISTAMINE H2 ANTAGONISTS for GASTROESOPHAGEAL REFLUX.
| Descriptor ID |
D054328
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| MeSH Number(s) |
D27.505.519.389.848
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Proton Pump Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Proton Pump Inhibitors".
This graph shows the total number of publications written about "Proton Pump Inhibitors" by people in UAMS Profiles by year, and whether "Proton Pump Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 2 | 3 | | 2023 | 1 | 1 | 2 | | 2022 | 1 | 1 | 2 | | 2021 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2019 | 1 | 1 | 2 | | 2018 | 2 | 2 | 4 | | 2017 | 0 | 1 | 1 | | 2016 | 3 | 0 | 3 | | 2015 | 1 | 0 | 1 | | 2014 | 2 | 1 | 3 | | 2013 | 2 | 2 | 4 | | 2012 | 2 | 0 | 2 | | 2011 | 1 | 2 | 3 | | 2010 | 5 | 0 | 5 | | 2009 | 1 | 1 | 2 | | 2008 | 2 | 0 | 2 | | 2007 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2005 | 4 | 2 | 6 | | 2004 | 1 | 0 | 1 | | 2003 | 3 | 1 | 4 | | 2002 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Proton Pump Inhibitors" by people in Profiles over the past ten years.
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Padhi BK, Khatib MN, Zahiruddin QS, Rustagi S, Sharma RK, Sah R, Satapathy P, Rao AP. Adverse cardiovascular outcomes associated with proton pump inhibitor use after percutaneous coronary intervention: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2024 07 17; 24(1):372.
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MacLaren R, Dionne JC, Granholm A, Alhazzani W, Szumita PM, Olsen K, Barletta JF, M?ller MH, Karvellas CJ, Wischmeyer P, DePriest A, Carlos V, Argetsinger D, Carothers JJ, Lee R, Napolitano L, Perri D, Naylor DF. Society of Critical Care Medicine and American Society of Health-System Pharmacists Guideline for the Prevention of Stress-Related Gastrointestinal Bleeding in Critically Ill Adults. Crit Care Med. 2024 Aug 01; 52(8):e421-e430.
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Chehade M, Dellon ES, Spergel JM, Collins MH, Rothenberg ME, Pesek RD, Hirano I, Liu R, Laws E, Mortensen E, Martincova R, Shabbir A, McCann E, Kamal MA, Kosloski MP, Hamilton JD, Samuely C, Lim WK, Wipperman MF, Farrell A, Patel N, Yancopoulos GD, Glotfelty L, Maloney J. Dupilumab for Eosinophilic Esophagitis in Patients 1 to 11 Years of Age. N Engl J Med. 2024 Jun 27; 390(24):2239-2251.
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Thompson EJ, Jeong A, Helfer VE, Shakhnovich V, Edginton A, Balevic SJ, James LP, Collier DN, Anand R, Gonzalez D. Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population. CPT Pharmacometrics Syst Pharmacol. 2024 Aug; 13(8):1394-1408.
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Gangwani MK, Ahmed Z, Ishtiaq R, Aziz M, Rani A, Dahiya DS, Priyanka F, Arif SF, Lee-Smith W, Sohail AH, Inamdar S, Hassan M. Hepatic encephalopathy with proton pump inhibitor use in post tips patients: a systematic review and meta-analysis. Minerva Gastroenterol (Torino). 2024 Sep; 70(3):353-358.
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Lancaster I, Sethi V, Patel D, Tamboli C, Pacer E, Steinhoff J, Mizrahi M, Willinger A. Antithrombotics and Gastrointestinal Prophylaxis: A Systematic Review. Cardiol Rev. 2024 Nov-Dec 01; 32(6):528-537.
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Haseeb M, McCarty TR, Jirapinyo P, Thompson CC. Letter to the Editor in Response to ACG Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease. Am J Gastroenterol. 2022 12 01; 117(12):2083.
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Feldman K, Kearns GL, Pearce RE, Abdel-Rahman SM, Steven Leeder J, Friesen A, Staggs VS, Gaedigk A, Weigel J, Shakhnovich V. Utility of the 13 C-pantoprazole breath test as a CYP2C19 phenotyping probe for children. Clin Transl Sci. 2022 05; 15(5):1155-1166.
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Shah S, Halvorson A, McBay B, Dorn C, Wilson O, Tuteja S, Chang KM, Cho K, Hauger R, Suzuki A, Hunt C, Siew E, Matheny M, Hung A, Greevy R, Roumie C. Proton-pump inhibitor use is not associated with severe COVID-19-related outcomes: a propensity score-weighted analysis of a national veteran cohort. Gut. 2022 07; 71(7):1447-1450.
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Liu JJ, Sloan ME, Owings AH, Figgins E, Gauthier J, Gharaibeh R, Robinson T, Williams H, Sindel CB, Backus F, Ayyalasomayajula K, Parker A, Senitko M, Abraham GE, Claggett B, Horwitz BH, Jobin C, Adelman RM, Diamond G, Glover SC. Increased ACE2 Levels and Mortality Risk of Patients With COVID-19 on Proton Pump Inhibitor Therapy. Am J Gastroenterol. 2021 08 01; 116(8):1638-1645.
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Gadiparthi C, Perisetti A, Sayana H, Tharian B, Inamdar S, Korman A. Gastrointestinal Bleeding in Patients with Severe SARS-CoV-2. Am J Gastroenterol. 2020 08; 115(8):1283-1285.
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Siddiqi A, Chaudhary FS, Naqvi HA, Saleh N, Farooqi R, Yousaf MN. Black esophagus: a syndrome of acute esophageal necrosis associated with active alcohol drinking. BMJ Open Gastroenterol. 2020 08; 7(1).
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Lyons K, Le LC, Pham YT, Borron C, Park JY, Tran CTD, Tran TV, Tran HT, Vu KT, Do CD, Pelucchi C, La Vecchia C, Zgibor J, Boffetta P, Luu HN. Gastric cancer: epidemiology, biology, and prevention: a mini review. Eur J Cancer Prev. 2019 09; 28(5):397-412.
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Choi K, Abu-Sbeih H, Samdani R, Nogueras Gonzalez G, Raju GS, Richards DM, Gao J, Subudhi S, Stroehlein J, Wang Y. Can Immune Checkpoint Inhibitors Induce Microscopic Colitis or a Brand New Entity? Inflamm Bowel Dis. 2019 01 10; 25(2):385-393.
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Shakhnovich V, Brian Smith P, Guptill JT, James LP, Collier DN, Wu H, Livingston CE, Zhao J, Kearns GL, Cohen-Wolkowiez M. A Population-Based Pharmacokinetic Model Approach to Pantoprazole Dosing for Obese Children and Adolescents. Paediatr Drugs. 2018 Oct; 20(5):483-495.
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Lovell DJ, Dare JA, Francis-Sedlak M, Ball J, LaMoreaux BD, Von Scheven E, Reinhardt A, Jerath R, Alpan O, Gupta R, Goldsmith D, Zeft A, Naddaf H, Gottlieb B, Jung L, Holt RJ. A 6-month, multicenter, open-label study of fixed dose naproxen/esomeprazole in adolescent patients with juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 2018 Jun 26; 16(1):41.
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Pesek RD, Gupta SK. Emerging drugs for eosinophilic esophagitis. Expert Opin Emerg Drugs. 2018 06; 23(2):173-183.
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McCarty TR, Itidiare M, Njei B, Rustagi T. Efficacy of transoral incisionless fundoplication for refractory gastroesophageal reflux disease: a systematic review and meta-analysis. Endoscopy. 2018 07; 50(7):708-725.
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Shakhnovich V, Smith PB, Guptill JT, James LP, Collier DN, Wu H, Livingston CE, Zhao J, Kearns GL. Obese Children Require Lower Doses of Pantoprazole Than Nonobese Peers to Achieve Equal Systemic Drug Exposures. J Pediatr. 2018 02; 193:102-108.e1.
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Pesek RD, Rettiganti M, O'Brien E, Beckwith S, Daniel C, Luo C, Scurlock AM, Chandler P, Levy RA, Perry TT, Kennedy JL, Chervinskiy S, Vonlanthen M, Casteel H, Fiedorek SC, Gibbons T, Jones SM. Effects of allergen sensitization on response to therapy in children with eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2017 08; 119(2):177-183.
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Hammond DA, Kathe N, Shah A, Martin BC. Cost-Effectiveness of Histamine2 Receptor Antagonists Versus Proton Pump Inhibitors for Stress Ulcer Prophylaxis in Critically Ill Patients. Pharmacotherapy. 2017 01; 37(1):43-53.
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Fallone CA, Chiba N, van Zanten SV, Fischbach L, Gisbert JP, Hunt RH, Jones NL, Render C, Leontiadis GI, Moayyedi P, Marshall JK. The Toronto Consensus for the Treatment of Helicobacter pylori Infection in Adults. Gastroenterology. 2016 Jul; 151(1):51-69.e14.
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McCaleb RV, Gandhi AS, Clark SM, Clemmons AB. Clinical Outcomes of Acid Suppressive Therapy Use in Hematology/Oncology Patients at an Academic Medical Center. Ann Pharmacother. 2016 07; 50(7):541-7.
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Park JY, Dunbar KB, Mitui M, Arnold CA, Lam-Himlin DM, Valasek MA, Thung I, Okwara C, Coss E, Cryer B, Doern CD. Helicobacter pylori Clarithromycin Resistance and Treatment Failure Are Common in the USA. Dig Dis Sci. 2016 08; 61(8):2373-2380.
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Hinson AM, Wilkerson BM, Rothman-Fitts I, Riggs AT, Stack BC, Bodenner DL. Hyperparathyroidism Associated with Long-Term Proton Pump Inhibitors Independent of Concurrent Bisphosphonate Therapy in Elderly Adults. J Am Geriatr Soc. 2015 Oct; 63(10):2070-3.
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