 Antipsychotic Agents
"Antipsychotic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
| Descriptor ID |
D014150
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| MeSH Number(s) |
D27.505.696.277.950.040 D27.505.954.427.210.950.040 D27.505.954.427.700.872.331
|
| Concept/Terms |
Antipsychotic Agents- Antipsychotic Agents
- Agents, Antipsychotic
- Antipsychotics
- Major Tranquilizers
- Tranquilizers, Major
- Tranquillizing Agents, Major
- Agents, Major Tranquillizing
- Major Tranquillizing Agents
- Neuroleptic Drugs
- Drugs, Neuroleptic
- Neuroleptics
- Tranquilizing Agents, Major
- Agents, Major Tranquilizing
- Major Tranquilizing Agents
- Antipsychotic Drugs
- Drugs, Antipsychotic
- Neuroleptic Agents
- Agents, Neuroleptic
Antipsychotic Effect- Antipsychotic Effect
- Effect, Antipsychotic
- Antipsychotic Effects
- Effects, Antipsychotic
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Below are MeSH descriptors whose meaning is more general than "Antipsychotic Agents".
Below are MeSH descriptors whose meaning is more specific than "Antipsychotic Agents".
This graph shows the total number of publications written about "Antipsychotic Agents" by people in UAMS Profiles by year, and whether "Antipsychotic Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 3 | 1 | 4 | | 2020 | 2 | 2 | 4 | | 2019 | 1 | 1 | 2 | | 2018 | 3 | 1 | 4 | | 2017 | 2 | 2 | 4 | | 2016 | 6 | 3 | 9 | | 2015 | 4 | 3 | 7 | | 2014 | 5 | 1 | 6 | | 2013 | 10 | 1 | 11 | | 2012 | 5 | 0 | 5 | | 2011 | 5 | 0 | 5 | | 2010 | 2 | 0 | 2 | | 2009 | 4 | 2 | 6 | | 2008 | 5 | 0 | 5 | | 2007 | 4 | 2 | 6 | | 2006 | 7 | 3 | 10 | | 2005 | 6 | 0 | 6 | | 2004 | 8 | 3 | 11 | | 2003 | 10 | 1 | 11 | | 2002 | 6 | 1 | 7 | | 2001 | 2 | 0 | 2 | | 2000 | 2 | 0 | 2 | | 1999 | 3 | 3 | 6 | | 1998 | 3 | 0 | 3 | | 1997 | 1 | 2 | 3 | | 1996 | 2 | 0 | 2 | | 1995 | 7 | 0 | 7 | | 1994 | 3 | 1 | 4 | | 1993 | 2 | 0 | 2 | | 1992 | 3 | 0 | 3 | | 1991 | 1 | 0 | 1 | | 1990 | 2 | 0 | 2 | | 1989 | 3 | 0 | 3 | | 1988 | 2 | 1 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Antipsychotic Agents" by people in Profiles over the past ten years.
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Ali MM, Oliveira I, Blanco M. Prescriptions of antipsychotics dispensed in long-term care facilities during the COVID-19 pandemic. Gen Hosp Psychiatry. 2022 Sep-Oct; 78:141-142.
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Coralic Z, Rader ES, Vinson DR, Wilson MP. Haloperidol Versus Ziprasidone With Concomitant Medications and Other Predictors of Physical Restraint Duration in the Emergency Department. J Emerg Med. 2022 May; 62(5):636-647.
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Choo TH, Xu Q, Budimirovic D, Lozano R, Esler AN, Frye RE, Andrews H, Velinov M. Height and BMI in fragile X syndrome: A longitudinal assessment. Obesity (Silver Spring). 2022 03; 30(3):743-750.
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Katz IR, Rogers MP, Lew R, Thwin SS, Doros G, Ahearn E, Ostacher MJ, DeLisi LE, Smith EG, Ringer RJ, Ferguson R, Hoffman B, Kaufman JS, Paik JM, Conrad CH, Holmberg EF, Boney TY, Huang GD, Liang MH. Lithium Treatment in the Prevention of Repeat Suicide-Related Outcomes in Veterans With Major Depression or Bipolar Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2022 01 01; 79(1):24-32.
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Das A, Minner R, Krain L, Spollen J. Delirium on clozapine: A tale of friend turned foe-A case report. Int J Psychiatry Med. 2021 11; 56(6):446-458.
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Schneider A, Mullinax S, Hall N, Acheson A, Oliveto AH, Wilson MP. Intramuscular medication for treatment of agitation in the emergency department: A systematic review of controlled trials. Am J Emerg Med. 2021 08; 46:193-199.
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Meltzer HY, Share DB, Jayathilake K, Salomon RM, Lee MA. Lurasidone Improves Psychopathology and Cognition in Treatment-Resistant Schizophrenia. J Clin Psychopharmacol. 2020 May-Jun; 40(3):240-249.
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Gupta HV. Teaching Video NeuroImages: Tardive diaphragmatic tremor. Neurology. 2020 02 11; 94(6):e656.
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Cohen BM. Evidence-Based Drug Treatment of Acute Depression in Bipolar Disorder. JAMA Psychiatry. 2019 12 01; 76(12):1314-1315.
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Cole JB, Klein LR, Mullinax SZ, Nordstrom KD, Driver BE, Wilson MP. Study Enrollment When "Preconsent" Is Utilized for a Randomized Clinical Trial of Two Treatments for Acute Agitation in the Emergency Department. Acad Emerg Med. 2019 05; 26(5):559-566.
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Chouinard VA, Henderson DC, Dalla Man C, Valeri L, Gray BE, Ryan KP, Cypess AM, Cobelli C, Cohen BM, Öngür D. Impaired insulin signaling in unaffected siblings and patients with first-episode psychosis. Mol Psychiatry. 2019 10; 24(10):1513-1522.
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Gressler LE, Martin BC, Hudson TJ, Painter JT. Relationship between concomitant benzodiazepine-opioid use and adverse outcomes among US veterans. Pain. 2018 03; 159(3):451-459.
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Patatanian E, Claborn MK. Drug-Induced Restless Legs Syndrome. Ann Pharmacother. 2018 07; 52(7):662-672.
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Pyne JM, Fischer EP, Mittal D, Owen R. A Patient-Centered Antipsychotic Medication Adherence Intervention: Results From a Randomized Controlled Trial. J Nerv Ment Dis. 2018 02; 206(2):142-148.
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Lewandowski KE, Sperry SH, Cohen BM, Norris LA, Fitzmaurice GM, Ongur D, Keshavan MS. Treatment to Enhance Cognition in Bipolar Disorder (TREC-BD): Efficacy of a Randomized Controlled Trial of Cognitive Remediation Versus Active Control. J Clin Psychiatry. 2017 Nov/Dec; 78(9):e1242-e1249.
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Wilson MP, Nordstrom K, Hopper A, Porter A, Castillo EM, Vilke GM. Risperidone in the Emergency Setting is Associated with More Hypotension in Elderly Patients. J Emerg Med. 2017 Nov; 53(5):735-739.
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Yeo QM, Wiley TL, Smith MN, Hammond DA. Oral Agents for the Management of Agitation and Agitated Delirium in Critically Ill Patients. Crit Care Nurs Q. 2017 Oct/Dec; 40(4):344-362.
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Painter JT, Owen R, Henderson KL, Bauer MS, Mittal D, Hudson TJ. Analysis of the Appropriateness of Off-Label Antipsychotic Use for Mental Health Indications in a Veteran Population. Pharmacotherapy. 2017 Apr; 37(4):438-446.
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Kirchner JE, Woodward EN, Smith JL, Curran GM, Kilbourne AM, Owen RR, Bauer MS. Implementation Science Supports Core Clinical Competencies: An Overview and Clinical Example. Prim Care Companion CNS Disord. 2016 Dec 08; 18(6).
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Huang JH, Park H, Iaconelli J, Berkovitch SS, Watmuff B, McPhie D, Öngür D, Cohen BM, Clish CB, Karmacharya R. Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines. J Proteome Res. 2017 02 03; 16(2):481-493.
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Hao L, Ben-David O, Babb SM, Futerman AH, Cohen BM, Buttner EA. Clozapine Modulates Glucosylceramide, Clears Aggregated Proteins, and Enhances ATG8/LC3 in Caenorhabditis elegans. Neuropsychopharmacology. 2017 Mar; 42(4):951-962.
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Saur T, Cohen BM, Ma Q, Babb SM, Buttner EA, Yao WD. Acute and chronic effects of clozapine on cholinergic transmission in cultured mouse superior cervical ganglion neurons. J Neurogenet. 2016 Sep - Dec; 30(3-4):297-305.
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Naeger S, Ali MM, Mutter R, Mark TL, Hughey L. Prescriptions Filled Following an Opioid-Related Hospitalization. Psychiatr Serv. 2016 11 01; 67(11):1262-1264.
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Wilson MP, Vilke GM, Hayden SR, Nordstrom K. Psychiatric Emergencies for Clinicians: Emergency Department Management of Neuroleptic Malignant Syndrome. J Emerg Med. 2016 Jul; 51(1):66-9.
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D'Onofrio S, Urbano FJ, Messias E, Garcia-Rill E. Lithium decreases the effects of neuronal calcium sensor protein 1 in pedunculopontine neurons. Physiol Rep. 2016 Mar; 4(6).
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Farrell MS, McCorvy JD, Huang XP, Urban DJ, White KL, Giguere PM, Doak AK, Bernstein AI, Stout KA, Park SM, Rodriguiz RM, Gray BW, Hyatt WS, Norwood AP, Webster KA, Gannon BM, Miller GW, Porter JH, Shoichet BK, Fantegrossi WE, Wetsel WC, Roth BL. In Vitro and In Vivo Characterization of the Alkaloid Nuciferine. PLoS One. 2016; 11(3):e0150602.
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An T, Choi J, Kim A, Lee JH, Nam Y, Park J, Sun Bk, Suh H, Kim CJ, Hwang SJ. Sustained release of risperidone from biodegradable microspheres prepared by in-situ suspension-evaporation process. Int J Pharm. 2016 Apr 30; 503(1-2):8-15.
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Campillo A, Castillo E, Vilke GM, Hopper A, Ryan V, Wilson MP. First-generation Antipsychotics Are Often Prescribed in the Emergency Department but Are Often Not Administered with Adjunctive Medications. J Emerg Med. 2015 Dec; 49(6):901-6.
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Hinds A, Coulter L, Hudson J, Seaton V. Screening for diabetes in patients receiving second-generation atypical antipsychotics. Am J Health Syst Pharm. 2015 Sep 01; 72(17 Suppl 2):S70-3.
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Aman M, Rettiganti M, Nagaraja HN, Hollway JA, McCracken J, McDougle CJ, Tierney E, Scahill L, Arnold LE, Hellings J, Posey DJ, Swiezy NB, Ghuman J, Grados M, Shah B, Vitiello B. Tolerability, Safety, and Benefits of Risperidone in Children and Adolescents with Autism: 21-Month Follow-up After 8-Week Placebo-Controlled Trial. J Child Adolesc Psychopharmacol. 2015 Aug; 25(6):482-93.
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Garner K, Padala P, Cox-Sullivan S. Reducing Antipsychotics for Dementia Patients in Nursing Homes. J Ark Med Soc. 2015 Jul; 112(1):12-3.
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Hopper AB, Vilke GM, Castillo EM, Campillo A, Davie T, Wilson MP. Ketamine use for acute agitation in the emergency department. J Emerg Med. 2015 Jun; 48(6):712-9.
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Bloomfield K, Pulliam E, Schultz E, Ward WL. Russian Adoption: A Case Study With Mixed Clinical Presentation. Clin Pediatr (Phila). 2015 Oct; 54(11):1123-4.
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Wilson MP, Brennan JJ, Modesti L, Deen J, Anderson L, Vilke GM, Castillo EM. Lengths of stay for involuntarily held psychiatric patients in the ED are affected by both patient characteristics and medication use. Am J Emerg Med. 2015 Apr; 33(4):527-30.
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Viverito K, Owen R, Mittal D, Li C, Williams JS. Management of new hyperglycemia in patients prescribed antipsychotics. Psychiatr Serv. 2014 Dec 01; 65(12):1502-5.
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Jensen PS. TOSCA: no longer just an opera. J Am Acad Child Adolesc Psychiatry. 2014 Sep; 53(9):938-41.
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Mittal D, Li C, Viverito K, Williams JS, Landes RD, Thapa PB, Owen R. Monitoring for metabolic side effects among outpatients with dementia receiving antipsychotics. Psychiatr Serv. 2014 Sep 01; 65(9):1147-53.
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Dyall J, Coleman CM, Hart BJ, Venkataraman T, Holbrook MR, Kindrachuk J, Johnson RF, Olinger GG, Jahrling PB, Laidlaw M, Johansen LM, Lear-Rooney CM, Glass PJ, Hensley LE, Frieman MB. Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection. Antimicrob Agents Chemother. 2014 Aug; 58(8):4885-93.
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Wilson MP, Minassian A, Bahramzi M, Campillo A, Vilke GM. Despite expert recommendations, second-generation antipsychotics are not often prescribed in the emergency department. J Emerg Med. 2014 Jun; 46(6):808-13.
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Wang X, Piccolo CW, Cohen BM, Buttner EA. Transient receptor potential melastatin (TRPM) channels mediate clozapine-induced phenotypes in Caenorhabditis elegans. J Neurogenet. 2014 Mar-Jun; 28(1-2):86-97.
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Pyne JM, Fischer EP, Gilmore L, McSweeney JC, Stewart KE, Mittal D, Bost JE, Valenstein M. Development of a Patient-Centered Antipsychotic Medication Adherence Intervention. Health Educ Behav. 2014 Jun; 41(3):315-24.
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Chandler A, Freeze-Ramsey R, Seupaul RA. Is the use of haloperidol a safe and effective method of tranquilization for patients with psychosis-induced aggression or agitation? Ann Emerg Med. 2014 Jun; 63(6):757-8.
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Cummings J, Isaacson S, Mills R, Williams H, Chi-Burris K, Corbett A, Dhall R, Ballard C. Pimavanserin for patients with Parkinson's disease psychosis: a randomised, placebo-controlled phase 3 trial. Lancet. 2014 Feb 08; 383(9916):533-40.
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Owen RR, Drummond KL, Viverito KM, Marchant K, Pope SK, Smith JL, Landes RD. Monitoring and managing metabolic effects of antipsychotics: a cluster randomized trial of an intervention combining evidence-based quality improvement and external facilitation. Implement Sci. 2013 Oct 08; 8:120.
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Wilson MP, MacDonald K, Vilke GM, Ronquillo L, Feifel D. Intramuscular ziprasidone: influence of alcohol and benzodiazepines on vital signs in the emergency setting. J Emerg Med. 2013 Dec; 45(6):901-8.
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Dhamane AD, Martin BC, Brixner DI, Hudson TJ, Said Q. Metabolic monitoring of patients prescribed second-generation antipsychotics. J Psychiatr Pract. 2013 Sep; 19(5):360-74.
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