2-Acetylaminofluorene
"2-Acetylaminofluorene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Descriptor ID |
D015073
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MeSH Number(s) |
D02.065.064.150 D02.241.081.018.110.080 D02.455.426.559.847.389.050 D04.615.389.050
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Concept/Terms |
2-Acetylaminofluorene- 2-Acetylaminofluorene
- 2 Acetylaminofluorene
- 2-Fluorenylacetamide
- 2 Fluorenylacetamide
- Fluoren-2-ylacetamide
- Fluoren 2 ylacetamide
- N-2-Fluorenylacetamide
- N 2 Fluorenylacetamide
- 2-AAF
- 2-Acetamidofluorene
- 2 Acetamidofluorene
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Below are MeSH descriptors whose meaning is more general than "2-Acetylaminofluorene".
Below are MeSH descriptors whose meaning is more specific than "2-Acetylaminofluorene".
This graph shows the total number of publications written about "2-Acetylaminofluorene" by people in UAMS Profiles by year, and whether "2-Acetylaminofluorene" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2016 | 0 | 1 | 1 | 2011 | 1 | 1 | 2 | 2010 | 1 | 0 | 1 | 2009 | 1 | 0 | 1 | 2008 | 1 | 0 | 1 | 2003 | 1 | 2 | 3 | 1991 | 0 | 1 | 1 | 1989 | 1 | 0 | 1 |
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Below are the most recent publications written about "2-Acetylaminofluorene" by people in Profiles over the past ten years.
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Kindrat I, Tryndyak V, de Conti A, Shpyleva S, Mudalige TK, Kobets T, Erstenyuk AM, Beland FA, Pogribny IP. MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis. Oncotarget. 2016 Jan 12; 7(2):1276-87.
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Hasan SK, Khan R, Ali N, Khan AQ, Rehman MU, Tahir M, Lateef A, Nafees S, Mehdi SJ, Rashid S, Shahid A, Sultana S. 18-? Glycyrrhetinic acid alleviates 2-acetylaminofluorene-induced hepatotoxicity in Wistar rats: Role in hyperproliferation, inflammation and oxidative stress. Hum Exp Toxicol. 2015 Jun; 34(6):628-41.
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