 Nicotinic Antagonists
"Nicotinic Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
| Descriptor ID |
D018733
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| MeSH Number(s) |
D27.505.519.625.120.200.700 D27.505.696.577.120.200.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nicotinic Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Nicotinic Antagonists".
This graph shows the total number of publications written about "Nicotinic Antagonists" by people in UAMS Profiles by year, and whether "Nicotinic Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 1 | 2 | | 2015 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2011 | 3 | 1 | 4 | | 2010 | 3 | 0 | 3 | | 2009 | 4 | 0 | 4 | | 2008 | 5 | 0 | 5 | | 2007 | 5 | 1 | 6 | | 2006 | 3 | 1 | 4 | | 2005 | 3 | 2 | 5 | | 2004 | 2 | 0 | 2 | | 2003 | 2 | 0 | 2 | | 2002 | 1 | 1 | 2 | | 2001 | 1 | 1 | 2 | | 2000 | 0 | 2 | 2 | | 1999 | 1 | 1 | 2 | | 1996 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nicotinic Antagonists" by people in Profiles over the past ten years.
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Maggio SE, Saunders MA, Nixon K, Prendergast MA, Zheng G, Crooks PA, Dwoskin LP, Bell RL, Bardo MT. An improved model of ethanol and nicotine co-use in female P rats: Effects of naltrexone, varenicline, and the selective nicotinic a6ß2* antagonist r-bPiDI. Drug Alcohol Depend. 2018 12 01; 193:154-161.
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Maggio SE, Saunders MA, Baxter TA, Nixon K, Prendergast MA, Zheng G, Crooks P, Dwoskin LP, Slack RD, Newman AH, Bell RL, Bardo MT. Effects of the nicotinic agonist varenicline, nicotinic antagonist r-bPiDI, and DAT inhibitor (R)-modafinil on co-use of ethanol and nicotine in female P rats. Psychopharmacology (Berl). 2018 05; 235(5):1439-1453.
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Beckmann JS, Meyer AC, Pivavarchyk M, Horton DB, Zheng G, Smith AM, Wooters TE, McIntosh JM, Crooks PA, Bardo MT, Dwoskin LP. r-bPiDI, an a6ß2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release and Nicotine Reinforcement. Neurochem Res. 2015 Oct; 40(10):2121-30.
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Crooks PA, Bardo MT, Dwoskin LP. Nicotinic receptor antagonists as treatments for nicotine abuse. Adv Pharmacol. 2014; 69:513-51.
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Peng C, Kimbrell MR, Tian C, Pack TF, Crooks PA, Fifer EK, Papke RL. Multiple modes of a7 nAChR noncompetitive antagonism of control agonist-evoked and allosterically enhanced currents. Mol Pharmacol. 2013 Sep; 84(3):459-75.
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Wala EP, Crooks PA, McIntosh JM, Holtman JR. Novel small molecule a9a10 nicotinic receptor antagonist prevents and reverses chemotherapy-evoked neuropathic pain in rats. Anesth Analg. 2012 Sep; 115(3):713-20.
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