 Neurodegenerative Diseases
"Neurodegenerative Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Descriptor ID |
D019636
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| MeSH Number(s) |
C10.574
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| Concept/Terms |
Neurodegenerative Diseases- Neurodegenerative Diseases
- Neurodegenerative Disease
- Degenerative Diseases, Neurologic
- Neurologic Degenerative Disease
- Degenerative Neurologic Diseases
- Degenerative Neurologic Disease
- Neurologic Disease, Degenerative
- Neurologic Diseases, Degenerative
- Nervous System Degenerative Diseases
- Neurodegenerative Disorders
- Neurodegenerative Disorder
- Neurologic Degenerative Conditions
- Degenerative Condition, Neurologic
- Degenerative Conditions, Neurologic
- Neurologic Degenerative Condition
- Neurologic Degenerative Diseases
- Degenerative Diseases, Nervous System
- Degenerative Neurologic Disorders
- Degenerative Neurologic Disorder
- Neurologic Disorder, Degenerative
- Neurologic Disorders, Degenerative
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Below are MeSH descriptors whose meaning is more general than "Neurodegenerative Diseases".
Below are MeSH descriptors whose meaning is more specific than "Neurodegenerative Diseases".
This graph shows the total number of publications written about "Neurodegenerative Diseases" by people in UAMS Profiles by year, and whether "Neurodegenerative Diseases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 0 | 1 | | 2018 | 5 | 0 | 5 | | 2017 | 3 | 1 | 4 | | 2016 | 1 | 2 | 3 | | 2015 | 1 | 0 | 1 | | 2014 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2011 | 3 | 2 | 5 | | 2010 | 0 | 1 | 1 | | 2009 | 1 | 1 | 2 | | 2008 | 1 | 0 | 1 | | 2007 | 3 | 0 | 3 | | 2005 | 1 | 0 | 1 | | 2004 | 2 | 1 | 3 | | 2002 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Neurodegenerative Diseases" by people in Profiles over the past ten years.
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Zhou F, Du G, Xie J, Gu J, Jia Q, Fan Y, Yu H, Zha Z, Wang K, Ouyang L, Shao L, Feng C, Fan G. RyRs mediate lead-induced neurodegenerative disorders through calcium signaling pathways. Sci Total Environ. 2020 Jan 20; 701:134901.
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Metz KA, Teng X, Coppens I, Lamb HM, Wagner BE, Rosenfeld JA, Chen X, Zhang Y, Kim HJ, Meadow ME, Wang TS, Haberlandt ED, Anderson GW, Leshinsky-Silver E, Bi W, Markello TC, Pratt M, Makhseed N, Garnica A, Danylchuk NR, Burrow TA, Jayakar P, McKnight D, Agadi S, Gbedawo H, Stanley C, Alber M, Prehl I, Peariso K, Ong MT, Mordekar SR, Parker MJ, Crooks D, Agrawal PB, Berry GT, Loddenkemper T, Yang Y, Maegawa GHB, Aouacheria A, Markle JG, Wohlschlegel JA, Hartman AL, Hardwick JM. KCTD7 deficiency defines a distinct neurodegenerative disorder with a conserved autophagy-lysosome defect. Ann Neurol. 2018 11; 84(5):766-780.
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Samanta D, Gokden M. PEHO syndrome: KIF1A mutation and decreased activity of mitochondrial respiratory chain complex. J Clin Neurosci. 2019 Mar; 61:298-301.
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Slone J, Peng Y, Chamberlin A, Harris B, Kaylor J, McDonald MT, Lemmon M, El-Dairi MA, Tchapyjnikov D, Gonzalez-Krellwitz LA, Sellars EA, McConkie-Rosell A, Reinholdt LG, Huang T. Biallelic mutations in FDXR cause neurodegeneration associated with inflammation. J Hum Genet. 2018 Dec; 63(12):1211-1222.
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Barham C, Fil D, Byrum SD, Rahmatallah Y, Glazko G, Kiaei M. RNA-Seq Analysis of Spinal Cord Tissues from hPFN1G118V Transgenic Mouse Model of ALS at Pre-symptomatic and End-Stages of Disease. Sci Rep. 2018 09 13; 8(1):13737.
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Smani D, Sarkar S, Raymick J, Kanungo J, Paule MG, Gu Q. Downregulation of 14-3-3 Proteins in a Kainic Acid-Induced Neurotoxicity Model. Mol Neurobiol. 2018 01; 55(1):122-129.
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Pogribny IP. MicroRNAs as biomarkers for clinical studies. Exp Biol Med (Maywood). 2018 02; 243(3):283-290.
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Salter MW, Stevens B. Microglia emerge as central players in brain disease. Nat Med. 2017 Sep 08; 23(9):1018-1027.
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Luo X, Rosenfeld JA, Yamamoto S, Harel T, Zuo Z, Hall M, Wierenga KJ, Pastore MT, Bartholomew D, Delgado MR, Rotenberg J, Lewis RA, Emrick L, Bacino CA, Eldomery MK, Coban Akdemir Z, Xia F, Yang Y, Lalani SR, Lotze T, Lupski JR, Lee B, Bellen HJ, Wangler MF. Clinically severe CACNA1A alleles affect synaptic function and neurodegeneration differentially. PLoS Genet. 2017 Jul; 13(7):e1006905.
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Ayyadevara S, Balasubramaniam M, Kakraba S, Alla R, Mehta JL, Shmookler Reis RJ. Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation. Antioxid Redox Signal. 2017 Dec 10; 27(17):1383-1396.
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Innabi A, Limaye K, Cobb S, Samant R, Virmani T. Caution! Self-supplementation may be injurious to your health. Acta Neurol Belg. 2017 09; 117(3):781-782.
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Sarkar S, Liachenko S, Paule MG, Bowyer J, Hanig JP. Brain endothelial dysfunction following pyrithiamine induced thiamine deficiency in the rat. Neurotoxicology. 2016 12; 57:298-309.
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Ayyadevara S, Mercanti F, Wang X, Mackintosh SG, Tackett AJ, Prayaga SV, Romeo F, Shmookler Reis RJ, Mehta JL. Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles. Hypertension. 2016 May; 67(5):1006-13.
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Neely BA, Soper JL, Gulland FM, Bell PD, Kindy M, Arthur JM, Janech MG. Proteomic analysis of cerebrospinal fluid in California sea lions (Zalophus californianus) with domoic acid toxicosis identifies proteins associated with neurodegeneration. Proteomics. 2015 Dec; 15(23-24):4051-63.
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Ayyadevara S, Balasubramaniam M, Gao Y, Yu LR, Alla R, Shmookler Reis R. Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexes. Aging Cell. 2015 Feb; 14(1):35-48.
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Thakur S, Sarkar B, Cholia RP, Gautam N, Dhiman M, Mantha AK. APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions. Exp Mol Med. 2014 Jul 18; 46:e106.
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Hayflick SJ, Kruer MC, Gregory A, Haack TB, Kurian MA, Houlden HH, Anderson J, Boddaert N, Sanford L, Harik SI, Dandu VH, Nardocci N, Zorzi G, Dunaway T, Tarnopolsky M, Skinner S, Holden KR, Frucht S, Hanspal E, Schrander-Stumpel C, Mignot C, Héron D, Saunders DE, Kaminska M, Lin JP, Lascelles K, Cuno SM, Meyer E, Garavaglia B, Bhatia K, de Silva R, Crisp S, Lunt P, Carey M, Hardy J, Meitinger T, Prokisch H, Hogarth P. ß-Propeller protein-associated neurodegeneration: a new X-linked dominant disorder with brain iron accumulation. Brain. 2013 Jun; 136(Pt 6):1708-17.
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Wight RD, Tull CA, Deel MW, Stroope BL, Eubanks AG, Chavis JA, Drew PD, Hensley LL. Resveratrol effects on astrocyte function: relevance to neurodegenerative diseases. Biochem Biophys Res Commun. 2012 Sep 14; 426(1):112-5.
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Gu Q, Schmued LC, Sarkar S, Paule MG, Raymick B. One-step labeling of degenerative neurons in unfixed brain tissue samples using Fluoro-Jade C. J Neurosci Methods. 2012 Jun 30; 208(1):40-3.
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Wongsurawat T, Jenjaroenpun P, Kwoh CK, Kuznetsov V. Quantitative model of R-loop forming structures reveals a novel level of RNA-DNA interactome complexity. Nucleic Acids Res. 2012 Jan; 40(2):e16.
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Hasan KM, Walimuni IS, Abid H, Frye RE, Ewing-Cobbs L, Wolinsky JS, Narayana PA. Multimodal quantitative magnetic resonance imaging of thalamic development and aging across the human lifespan: implications to neurodegeneration in multiple sclerosis. J Neurosci. 2011 Nov 16; 31(46):16826-32.
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Ju YE, Larson-Prior L, Duntley S. RBD and antidepressants. Sleep Med. 2012 Feb; 13(2):211-2.
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Neymotin A, Calingasan NY, Wille E, Naseri N, Petri S, Damiano M, Liby KT, Risingsong R, Sporn M, Beal MF, Kiaei M. Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis. Free Radic Biol Med. 2011 Jul 01; 51(1):88-96.
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Ju YE, Larson-Prior L, Duntley S. Changing demographics in REM sleep behavior disorder: possible effect of autoimmunity and antidepressants. Sleep Med. 2011 Mar; 12(3):278-83.
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Olazarán J, Reisberg B, Clare L, Cruz I, Peña-Casanova J, Del Ser T, Woods B, Beck C, Auer S, Lai C, Spector A, Fazio S, Bond J, Kivipelto M, Brodaty H, Rojo JM, Collins H, Teri L, Mittelman M, Orrell M, Feldman HH, Muñiz R. Nonpharmacological therapies in Alzheimer's disease: a systematic review of efficacy. Dement Geriatr Cogn Disord. 2010; 30(2):161-78.
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