3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
"3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ketone oxidoreductase that catalyzes the overall conversion of alpha-keto acids to ACYL-CoA and CO2. The enzyme requires THIAMINE DIPHOSPHATE as a cofactor. Defects in genes that code for subunits of the enzyme are a cause of MAPLE SYRUP URINE DISEASE. The enzyme was formerly classified as EC 1.2.4.3.
Descriptor ID |
D042942
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MeSH Number(s) |
D08.811.682.657.350.760
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Concept/Terms |
3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)- 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
- 2-Oxoisocaproate Dehydrogenase
- 2 Oxoisocaproate Dehydrogenase
- Dehydrogenase, 2-Oxoisocaproate
- 2-Oxoisovalerate Dehydrogenase (Lipoamide)
- Branched-Chain Keto Acid Dehydrogenase
- Branched Chain Keto Acid Dehydrogenase
- BCKA Decarboxylase
- Decarboxylase, BCKA
- Branched Chain Alpha-Keto Acid Decarboxylase
- Branched Chain Alpha Keto Acid Decarboxylase
- Branched Chain Ketoacid Dehydrogenase
- Branched-Chain 2-Oxo Acid Dehydrogenase
- Branched Chain 2 Oxo Acid Dehydrogenase
- Branched-Chain Oxo-Acid Dehydrogenase
- Branched Chain Oxo Acid Dehydrogenase
- Dehydrogenase, Branched-Chain Oxo-Acid
- Oxo-Acid Dehydrogenase, Branched-Chain
- Alpha-Keto Acid Dehydrogenase
- Acid Dehydrogenase, Alpha-Keto
- Alpha Keto Acid Dehydrogenase
- Dehydrogenase, Alpha-Keto Acid
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Below are MeSH descriptors whose meaning is more general than "3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)".
Below are MeSH descriptors whose meaning is more specific than "3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)".
This graph shows the total number of publications written about "3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)" by people in UAMS Profiles by year, and whether "3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2013 | 1 | 2 | 3 | 2011 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)" by people in Profiles over the past ten years.
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Kadota Y, Toyoda T, Kitaura Y, Adams SH, Shimomura Y. Regulation of hepatic branched-chain a-ketoacid dehydrogenase complex in rats fed a high-fat diet. Obes Res Clin Pract. 2013 Dec; 7(6):e439-44.
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She P, Olson KC, Kadota Y, Inukai A, Shimomura Y, Hoppel CL, Adams SH, Kawamata Y, Matsumoto H, Sakai R, Lang CH, Lynch CJ. Leucine and protein metabolism in obese Zucker rats. PLoS One. 2013; 8(3):e59443.
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Lackey DE, Lynch CJ, Olson KC, Mostaedi R, Ali M, Smith WH, Karpe F, Humphreys S, Bedinger DH, Dunn TN, Thomas AP, Oort PJ, Kieffer DA, Amin R, Bettaieb A, Haj FG, Permana P, Anthony TG, Adams SH. Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity. Am J Physiol Endocrinol Metab. 2013 Jun 01; 304(11):E1175-87.
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