 Oligonucleotides
"Oligonucleotides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed)
| Descriptor ID |
D009841
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| MeSH Number(s) |
D13.695.578.424
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Oligonucleotides".
Below are MeSH descriptors whose meaning is more specific than "Oligonucleotides".
This graph shows the total number of publications written about "Oligonucleotides" by people in UAMS Profiles by year, and whether "Oligonucleotides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 2 | 0 | 2 | | 2020 | 4 | 0 | 4 | | 2019 | 3 | 0 | 3 | | 2018 | 2 | 0 | 2 | | 2017 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2012 | 0 | 3 | 3 | | 2011 | 0 | 1 | 1 | | 2010 | 1 | 3 | 4 | | 2009 | 0 | 1 | 1 | | 2008 | 2 | 0 | 2 | | 2007 | 1 | 1 | 2 | | 2006 | 0 | 1 | 1 | | 2005 | 1 | 6 | 7 | | 2004 | 0 | 3 | 3 | | 2003 | 0 | 2 | 2 | | 2002 | 2 | 3 | 5 | | 2001 | 1 | 2 | 3 | | 1999 | 1 | 0 | 1 | | 1997 | 2 | 0 | 2 | | 1993 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oligonucleotides" by people in Profiles over the past ten years.
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Christov PP, Richie-Jannetta R, Kingsley PJ, Vemulapalli A, Kim K, Sulikowski GA, Rizzo CJ, Ketkar A, Eoff RL, Rouzer CA, Marnett LJ. Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-M1dG, the Genomic Metabolite of M1dG, and Liquid Chromatography-Tandem Mass Spectrometry Analysis of Its In Vitro Bypass by Human Polymerase ?. Chem Res Toxicol. 2021 12 20; 34(12):2567-2578.
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Shao J, Yan Y, Ding D, Wang D, He Y, Pan Y, Yan W, Kharbanda A, Li HY, Huang H. Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O'PROTAC): Effective Targeting of LEF1 and ERG. Adv Sci (Weinh). 2021 10; 8(20):e2102555.
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Dyck PJB, Kincaid JC, Wiesman JF, Polydefkis M, Litchy WJ, Mauermann ML, Ackermann EJ, Guthrie S, Pollock M, Jung SW, Baker BF, Dyck PJ. mNIS+7 and lower limb function in inotersen treatment of hereditary transthyretin-mediated amyloidosis. Muscle Nerve. 2020 10; 62(4):502-508.
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Harada Y, Rao VK, Arya K, Kuntz NL, DiDonato CJ, Napchan-Pomerantz G, Agarwal A, Stefans V, Katsuno M, Veerapandiyan A. Combination molecular therapies for type 1 spinal muscular atrophy. Muscle Nerve. 2020 10; 62(4):550-554.
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Dyck PJB, Coelho T, Waddington Cruz M, Brannagan TH, Khella S, Karam C, Berk JL, Polydefkis MJ, Kincaid JC, Wiesman JF, Litchy WJ, Mauermann ML, Ackermann EJ, Baker BF, Jung SW, Guthrie S, Pollock M, Dyck PJ. Neuropathy symptom and change: Inotersen treatment of hereditary transthyretin amyloidosis. Muscle Nerve. 2020 10; 62(4):509-515.
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Feldman AG, Parsons JA, Dutmer CM, Veerapandiyan A, Hafberg E, Maloney N, Mack CL. Subacute Liver Failure Following Gene Replacement Therapy for Spinal Muscular Atrophy Type 1. J Pediatr. 2020 10; 225:252-258.e1.
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Veerapandiyan A, Eichinger K, Guntrum D, Kwon J, Baker L, Collins E, Ciafaloni E. Nusinersen for older patients with spinal muscular atrophy: A real-world clinical setting experience. Muscle Nerve. 2020 02; 61(2):222-226.
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Pavagada S, Channon RB, Chang JYH, Kim SH, MacIntyre D, Bennett PR, Terzidou V, Ladame S. Oligonucleotide-templated lateral flow assays for amplification-free sensing of circulating microRNAs. Chem Commun (Camb). 2019 Oct 15; 55(83):12451-12454.
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De Fazio AF, El-Sagheer AH, Kahn JS, Nandhakumar I, Burton MR, Brown T, Muskens OL, Gang O, Kanaras AG. Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices. ACS Nano. 2019 05 28; 13(5):5771-5777.
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Claborn MK, Stevens DL, Walker CK, Gildon BL. Nusinersen: A Treatment for Spinal Muscular Atrophy. Ann Pharmacother. 2019 01; 53(1):61-69.
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Veerapandiyan A, Pal R, D'Ambrosio S, Young I, Eichinger K, Collins E, Westesson PL, Kwon J, Ciafaloni E. Cervical puncture to deliver nusinersen in patients with spinal muscular atrophy. Neurology. 2018 08 14; 91(7):e620-e624.
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Dyck PJ, Kincaid JC, Dyck PJB, Chaudhry V, Goyal NA, Alves C, Salhi H, Wiesman JF, Labeyrie C, Robinson-Papp J, Cardoso M, Laura M, Ruzhansky K, Cortese A, Brannagan TH, Khoury J, Khella S, Waddington-Cruz M, Ferreira J, Wang AK, Pinto MV, Ayache SS, Benson MD, Berk JL, Coelho T, Polydefkis M, Gorevic P, Adams DH, Plante-Bordeneuve V, Whelan C, Merlini G, Heitner S, Drachman BM, Conceição I, Klein CJ, Gertz MA, Ackermann EJ, Hughes SG, Mauermann ML, Bergemann R, Lodermeier KA, Davies JL, Carter RE, Litchy WJ. Assessing mNIS+7Ionis and international neurologists' proficiency in a familial amyloidotic polyneuropathy trial. Muscle Nerve. 2017 Nov; 56(5):901-911.
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Al Sulaiman D, Chang JYH, Ladame S. Subnanomolar Detection of Oligonucleotides through Templated Fluorogenic Reaction in Hydrogels: Controlling Diffusion to Improve Sensitivity. Angew Chem Int Ed Engl. 2017 05 02; 56(19):5247-5251.
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Gubrij IB, Pangle AK, Pang L, Johnson LG. Reversal of MicroRNA Dysregulation in an Animal Model of Pulmonary Hypertension. PLoS One. 2016; 11(1):e0147827.
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Katragadda L, Carter BZ, Borthakur G. XIAP antisense therapy with AEG 35156 in acute myeloid leukemia. Expert Opin Investig Drugs. 2013 May; 22(5):663-70.
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Kotapati S, Maddukuri L, Wickramaratne S, Seneviratne U, Goggin M, Pence MG, Villalta P, Guengerich FP, Marnett L, Tretyakova N. Translesion synthesis across 1,N6-(2-hydroxy-3-hydroxymethylpropan-1,3-diyl)-2'-deoxyadenosine (1,N6-?-HMHP-dA) adducts by human and archebacterial DNA polymerases. J Biol Chem. 2012 Nov 09; 287(46):38800-11.
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