 Diabetes Mellitus, Type 1
"Diabetes Mellitus, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Descriptor ID |
D003922
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| MeSH Number(s) |
C18.452.394.750.124 C19.246.267 C20.111.327
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| Concept/Terms |
Diabetes Mellitus, Type 1- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Insulin-Dependent
- Diabetes Mellitus, Insulin Dependent
- Insulin-Dependent Diabetes Mellitus
- Diabetes Mellitus, Insulin-Dependent, 1
- Diabetes Mellitus, Juvenile-Onset
- Diabetes Mellitus, Juvenile Onset
- Juvenile-Onset Diabetes Mellitus
- Type 1 Diabetes Mellitus
- Diabetes Mellitus, Sudden-Onset
- Diabetes Mellitus, Sudden Onset
- Mellitus, Sudden-Onset Diabetes
- Sudden-Onset Diabetes Mellitus
- Diabetes Mellitus, Type I
- IDDM
- Insulin-Dependent Diabetes Mellitus 1
- Insulin Dependent Diabetes Mellitus 1
- Juvenile-Onset Diabetes
- Diabetes, Juvenile-Onset
- Juvenile Onset Diabetes
- Diabetes Mellitus, Brittle
- Brittle Diabetes Mellitus
- Diabetes Mellitus, Ketosis-Prone
- Diabetes Mellitus, Ketosis Prone
- Ketosis-Prone Diabetes Mellitus
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Below are MeSH descriptors whose meaning is more general than "Diabetes Mellitus, Type 1".
Below are MeSH descriptors whose meaning is more specific than "Diabetes Mellitus, Type 1".
This graph shows the total number of publications written about "Diabetes Mellitus, Type 1" by people in UAMS Profiles by year, and whether "Diabetes Mellitus, Type 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2023 | 2 | 0 | 2 | | 2022 | 9 | 0 | 9 | | 2021 | 6 | 1 | 7 | | 2020 | 10 | 0 | 10 | | 2019 | 4 | 0 | 4 | | 2018 | 7 | 0 | 7 | | 2017 | 4 | 0 | 4 | | 2016 | 9 | 1 | 10 | | 2015 | 3 | 1 | 4 | | 2014 | 5 | 1 | 6 | | 2013 | 4 | 1 | 5 | | 2012 | 2 | 0 | 2 | | 2011 | 5 | 1 | 6 | | 2010 | 5 | 0 | 5 | | 2009 | 2 | 1 | 3 | | 2007 | 4 | 0 | 4 | | 2006 | 1 | 0 | 1 | | 2005 | 6 | 1 | 7 | | 2004 | 1 | 0 | 1 | | 2003 | 2 | 1 | 3 | | 2002 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 1999 | 2 | 2 | 4 | | 1998 | 0 | 1 | 1 | | 1997 | 5 | 0 | 5 | | 1995 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1992 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1990 | 0 | 1 | 1 | | 1988 | 1 | 0 | 1 |
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Below are the most recent publications written about "Diabetes Mellitus, Type 1" by people in Profiles over the past ten years.
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Mokhtari P, Jambal P, Metos JM, Shankar K, Anandh Babu PV. Microbial taxonomic and functional shifts in adolescents with type 1 diabetes are associated with clinical and dietary factors. EBioMedicine. 2023 Jul; 93:104641.
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Yuan X, Amin V, Zhu T, Kittaka M, Ueki Y, Bellido TM, Turkkahraman H. Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling. J Periodontol. 2023 02; 94(2):277-289.
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Agarwal S, Rioles N, Majidi S, Rapaport R, Ebekozien O. Commentary on the T1D exchange quality improvement collaborative learning session November 2022 abstracts. J Diabetes. 2022 11; 14(11):780-782.
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Tas E, Bai S, Mak D, Diaz EC, Dranoff JA. Obesity, but not glycemic control, predicts liver steatosis in children with type 1 diabetes. J Diabetes Complications. 2022 Dec; 36(12):108341.
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Barua S, A Wierzchowska-McNew R, Deutz NEP, Sabharwal A. Discordance between postprandial plasma glucose measurement and continuous glucose monitoring. Am J Clin Nutr. 2022 10 06; 116(4):1059-1069.
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Mathias P, Mahali LP, Agarwal S. Targeting Technology in Underserved Adults With Type 1 Diabetes: Effect of Diabetes Practice Transformations on Improving Equity in CGM Prescribing Behaviors. Diabetes Care. 2022 10 01; 45(10):2231-2237.
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Russell SJ, Beck RW, Damiano ER, El-Khatib FH, Ruedy KJ, Balliro CA, Li Z, Calhoun P, Wadwa RP, Buckingham B, Zhou K, Daniels M, Raskin P, White PC, Lynch J, Pettus J, Hirsch IB, Goland R, Buse JB, Kruger D, Mauras N, Muir A, McGill JB, Cogen F, Weissberg-Benchell J, Sherwood JS, Castellanos LE, Hillard MA, Tuffaha M, Putman MS, Sands MY, Forlenza G, Slover R, Messer LH, Cobry E, Shah VN, Polsky S, Lal R, Ekhlaspour L, Hughes MS, Basina M, Hatipoglu B, Olansky L, Bhangoo A, Forghani N, Kashmiri H, Sutton F, Choudhary A, Penn J, Jafri R, Rayas M, Escaname E, Kerr C, Favela-Prezas R, Boeder S, Trikudanathan S, Williams KM, Leibel N, Kirkman MS, Bergamo K, Klein KR, Dostou JM, Machineni S, Young LA, Diner JC, Bhan A, Jones JK, Benson M, Bird K, Englert K, Permuy J, Cossen K, Felner E, Salam M, Silverstein JM, Adamson S, Cedeno A, Meighan S, Dauber A. Multicenter, Randomized Trial of a Bionic Pancreas in Type 1 Diabetes. N Engl J Med. 2022 09 29; 387(13):1161-1172.
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Kalaitzoglou E, Fowlkes JL, Thrailkill KM. Mouse models of type 1 diabetes and their use in skeletal research. Curr Opin Endocrinol Diabetes Obes. 2022 08 01; 29(4):318-325.
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Agarwal S, Simmonds I, Myers AK. The Use of Diabetes Technology to Address Inequity in Health Outcomes: Limitations and Opportunities. Curr Diab Rep. 2022 07; 22(7):275-281.
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Agarwal S, Crespo-Ramos G, Leung SL, Finnan M, Park T, McCurdy K, Gonzalez JS, Long JA. Solutions to Address Inequity in Diabetes Technology Use in Type 1 Diabetes: Results from Multidisciplinary Stakeholder Co-creation Workshops. Diabetes Technol Ther. 2022 06; 24(6):381-389.
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Cabrera SM, Coren AT, Pant T, Ciecko AE, Jia S, Roethle MF, Simpson PM, Atkinson SN, Salzman NH, Chen YG, Hessner MJ. Probiotic normalization of systemic inflammation in siblings of type 1 diabetes patients: an open-label pilot study. Sci Rep. 2022 02 28; 12(1):3306.
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Gurram V, Gurung K, Rogers J, Farney AC, Orlando G, Jay C, Reeves-Daniel A, Mena-Gutierrez A, Sakhovskaya N, Doares W, Kaczmorski S, Sharda B, Gautreaux MD, Stratta RJ. Do pretransplant C-peptide levels predict outcomes following simultaneous pancreas-kidney transplantation? A matched case-control study. Clin Transplant. 2022 01; 36(1):e14498.
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Agarwal S, Crespo-Ramos G, Long JA, Miller VA. "I Didn't Really Have a Choice": Qualitative Analysis of Racial-Ethnic Disparities in Diabetes Technology Use Among Young Adults with Type 1 Diabetes. Diabetes Technol Ther. 2021 09; 23(9):616-622.
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Hanna KM, Hansen JR, Harp KA, Betts KJ, Hudson DB, Campbell-Grossman C, Hanish A. Habit and Routine Interventions with Emerging Adults with Diabetes: An Integrative Review. West J Nurs Res. 2022 Dec; 44(12):1155-1166.
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Wang Y, Niu A, Pan Y, Cao S, Terker AS, Wang S, Fan X, Toth CL, Ramirez Solano MA, Michell DL, Contreras D, Allen RM, Zhu W, Sheng Q, Fogo AB, Vickers KC, Zhang MZ, Harris RC. Profile of Podocyte Translatome During Development of Type 2 and Type 1 Diabetic Nephropathy Using Podocyte-Specific TRAP mRNA RNA-seq. Diabetes. 2021 10; 70(10):2377-2390.
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Alonso GT, Ebekozien O, Gallagher MP, Rompicherla S, Lyons SK, Choudhary A, Majidi S, Pinnaro CT, Balachandar S, Gangat M, Curda Roberts AJ, Marks BE, Creo A, Sanchez J, Seeherunvong T, Jimenez-Vega J, Patel NS, Wood JR, Gabriel L, Sumpter KM, Wilkes M, Rapaport R, Cymbaluk A, Wong JC, Sanda S, Albanese-O'neill A. Diabetic ketoacidosis drives COVID-19 related hospitalizations in children with type 1 diabetes. J Diabetes. 2021 Aug; 13(8):681-687.
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Cerise A, Chen JM, Powelson JA, Lutz AJ, Fridell JA. Pancreas transplantation would be easy if the recipients were not diabetic: A practical guide to post-operative management of diabetic complications in pancreas transplant recipients. Clin Transplant. 2021 05; 35(5):e14270.
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Sultan HK, El-Ayat WM, AbouGhalia AH, Lasheen NN, Moustafa AS. Study of long non-coding RNA and mitochondrial dysfunction in diabetic rats. Tissue Cell. 2021 Aug; 71:101516.
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Polsky S, Foster NC, DuBose SN, Agarwal S, Lyons S, Peters AL, Uwaifo GI, DiMeglio LA, Sherr JL, Levy CJ. Incident diabetes complications among women with type 1 diabetes based on parity. J Matern Fetal Neonatal Med. 2022 Dec; 35(24):4629-4634.
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Tosur M, Cleves MA, Sosenko JM, Libman I, Baidal DA, Balasubramanyam A, Redondo MJ. The Effect of Ethnicity in the Rate of Beta-Cell Functional Loss in the First 3 Years After Type 1 Diabetes Diagnosis. J Clin Endocrinol Metab. 2020 12 01; 105(12).
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Singh A, Dasgupta M, Retherford D, Fiallo-Scharer R, Simpson PM, Panepinto JA. Measurement properties of Patient Reported Outcomes Measurement Information System domains for children with type 1 diabetes. Pediatr Diabetes. 2021 03; 22(2):335-344.
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Ismail HM, Cleves MA, Xu P, Libman IM, Becker DJ, Marks JB, Skyler JS, Palmer JP, Sosenko JM. The Pathological Evolution of Glucose Response Curves During the Progression to Type 1 Diabetes in the TrialNet Pathway to Prevention Study. Diabetes Care. 2020 11; 43(11):2668-2674.
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Mejia-Otero JD, Adhikari S, White PC. Risk factors for hospitalization in youth with type 1 diabetes: Development and validation of a multivariable prediction model. Pediatr Diabetes. 2020 11; 21(7):1268-1276.
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Crochiere RJ, Hughes Lansing A, Carracher A, Vaid E, Stanger C. Attentional bias to diabetes cues mediates disease management improvements in a pilot randomized controlled trial for adolescents with type 1 diabetes. J Health Psychol. 2021 12; 26(14):2699-2710.
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Sosenko JM, Skyler JS, Herold KC, Schatz DA, Haller MJ, Pugliese A, Cleves M, Geyer S, Rafkin LE, Matheson D, Palmer JP. Slowed Metabolic Decline After 1 Year of Oral Insulin Treatment Among Individuals at High Risk for Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1) and TrialNet Oral Insulin Prevention Trials. Diabetes. 2020 08; 69(8):1827-1832.
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Wolfgram P, Zhang L, Simpson P, Fiallo-Scharer R. Clinical associations of quarterly Patient Health Questionnaire-9 depression screening results in adolescents with type 1 diabetes. Pediatr Diabetes. 2020 08; 21(5):871-877.
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Martin LD, Hoagland MA, Rhodes ET, Wolfsdorf JI, Hamrick JL. Perioperative Management of Pediatric Patients With Type 1 Diabetes Mellitus, Updated Recommendations for Anesthesiologists. Anesth Analg. 2020 04; 130(4):821-827.
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Ismail HM, Becker DJ, Libman I, Herold KC, Redondo MJ, Atkinson MA, Cleves MA, Palmer J, Sosenko J. Early and late C-peptide responses during oral glucose tolerance testing are oppositely predictive of type 1 diabetes in autoantibody-positive individuals. Diabetes Obes Metab. 2020 06; 22(6):997-1000.
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Ismail HM, Evans-Molina C, DiMeglio LA, Becker DJ, Libman I, Sims EK, Boulware D, Herold KC, Rafkin L, Skyler J, Cleves MA, Palmer J, Sosenko JM. Associations of HbA1c with the timing of C-peptide responses during the oral glucose tolerance test at the diagnosis of type 1 diabetes. Pediatr Diabetes. 2019 06; 20(4):408-413.
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Lopes-Virella MF, Baker NL, Hunt KJ, Hammad SM, Arthur J, Virella G, Klein RL. Glycosylated sphingolipids and progression to kidney dysfunction in type 1 diabetes. J Clin Lipidol. 2019 May - Jun; 13(3):481-491.e1.
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Kumar N, Mehra NK, Kanga U, Kaur G, Tandon N, Chuzho N, Mishra G, Neolia SC. Diverse human leukocyte antigen association of type 1 diabetes in north India. J Diabetes. 2019 Sep; 11(9):719-728.
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Lansing AH, Stoianova M, Stanger C. Adolescent Emotional Control Moderates Benefits of a Multicomponent Intervention to Improve Type 1 Diabetes Adherence: A Pilot Randomized Controlled Trial. J Pediatr Psychol. 2019 01 01; 44(1):126-136.
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Crochiere RJ, Lansing AH, Carracher A, Stanger C. Executive function and somatic problems in adolescents with above target glycemic control. Pediatr Diabetes. 2019 02; 20(1):119-126.
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Stanger C, Lansing AH, Scherer E, Budney A, Christiano AS, Casella SJ. A Web-Delivered Multicomponent Intervention for Adolescents with Poorly Controlled Type 1 Diabetes: A Pilot Randomized Controlled Trial. Ann Behav Med. 2018 11 12; 52(12):1010-1022.
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Cabrera SM, Engle S, Kaldunski M, Jia S, Geoffrey R, Simpson P, Szabo A, Speake C, Greenbaum CJ, Chen YG, Hessner MJ. Innate immune activity as a predictor of persistent insulin secretion and association with responsiveness to CTLA4-Ig treatment in recent-onset type 1 diabetes. Diabetologia. 2018 11; 61(11):2356-2370.
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Stoianova M, Tampke EC, Lansing AH, Stanger C. Delay discounting associated with challenges to treatment adherence and glycemic control in young adults with type 1 diabetes. Behav Processes. 2018 Dec; 157:474-477.
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Vaid E, Lansing AH, Stanger C. Problems With Self-Regulation, Family Conflict, and Glycemic Control in Adolescents Experiencing Challenges With Managing Type 1 Diabetes. J Pediatr Psychol. 2018 06 01; 43(5):525-533.
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Edem D, McCarthy P, Ng JM, Stefanovic-Racic M, Korytkowski MT. Insulin Pump Therapy: Patient Practices and Glycemic Outcomes. J Diabetes Sci Technol. 2018 11; 12(6):1250-1251.
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Yin GN, Jin HR, Choi MJ, Limanjaya A, Ghatak K, Minh NN, Ock J, Kwon MH, Song KM, Park HJ, Kim HM, Kwon YG, Ryu JK, Suh JK. Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway. Diabetes. 2018 06; 67(6):1149-1161.
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Bockus LB, Matsuzaki S, Vadvalkar SS, Young ZT, Giorgione JR, Newhardt MF, Kinter M, Humphries KM. Cardiac Insulin Signaling Regulates Glycolysis Through Phosphofructokinase 2 Content and Activity. J Am Heart Assoc. 2017 Dec 04; 6(12).
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Bansal S, Marwa A, Kasturi K, Perez-Colon S. Improving paediatric residents' knowledge and perspectives regarding the insulin pump using a novel educational workshop. Postgrad Med J. 2018 Feb; 94(1108):87-91.
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Lansing AH, Stanger C, Crochiere R, Carracher A, Budney A. Delay discounting and parental monitoring in adolescents with poorly controlled type 1 diabetes. J Behav Med. 2017 Dec; 40(6):864-874.
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Raisingani M, Preneet B, Kohn B, Yakar S. Skeletal growth and bone mineral acquisition in type 1 diabetic children; abnormalities of the GH/IGF-1 axis. Growth Horm IGF Res. 2017 06; 34:13-21.
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Garvey KC, Foster NC, Agarwal S, DiMeglio LA, Anderson BJ, Corathers SD, Desimone ME, Libman IM, Lyons SK, Peters AL, Raymond JK, Laffel LM. Health Care Transition Preparation and Experiences in a U.S. National Sample of Young Adults With Type 1 Diabetes. Diabetes Care. 2017 Mar; 40(3):317-324.
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Kalaitzoglou E, Popescu I, Bunn RC, Fowlkes JL, Thrailkill KM. Effects of Type 1 Diabetes on Osteoblasts, Osteocytes, and Osteoclasts. Curr Osteoporos Rep. 2016 12; 14(6):310-319.
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Thrailkill KM, Nyman JS, Bunn RC, Uppuganti S, Thompson KL, Lumpkin CK, Kalaitzoglou E, Fowlkes JL. The impact of SGLT2 inhibitors, compared with insulin, on diabetic bone disease in a mouse model of type 1 diabetes. Bone. 2017 Jan; 94:141-151.
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Maycas M, McAndrews KA, Sato AY, Pellegrini GG, Brown DM, Allen MR, Plotkin LI, Gortazar AR, Esbrit P, Bellido T. PTHrP-Derived Peptides Restore Bone Mass and Strength in Diabetic Mice: Additive Effect of Mechanical Loading. J Bone Miner Res. 2017 Mar; 32(3):486-497.
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Iyer S, Han L, Ambrogini E, Yavropoulou M, Fowlkes J, Manolagas SC, Almeida M. Deletion of FoxO1, 3, and 4 in Osteoblast Progenitors Attenuates the Loss of Cancellous Bone Mass in a Mouse Model of Type 1 Diabetes. J Bone Miner Res. 2017 01; 32(1):60-69.
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Lansing AH, Stanger C, Budney A, Christiano AS, Casella SJ. Pilot Study of a Web-Delivered Multicomponent Intervention for Rural Teens with Poorly Controlled Type 1 Diabetes. J Diabetes Res. 2016; 2016:7485613.
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Iyer D, Choudhary D, Agwu JC. Timeliness of referral of children with new onset type 1 diabetes. Postgrad Med J. 2017 May; 93(1099):242-244.
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Choudhary A. Sick Day Management in Children and Adolescents with Type 1 Diabetes. J Ark Med Soc. 2016 Jun; 112(14):284-6.
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Tellechea A, Leal EC, Kafanas A, Auster ME, Kuchibhotla S, Ostrovsky Y, Tecilazich F, Baltzis D, Zheng Y, Carvalho E, Zabolotny JM, Weng Z, Petra A, Patel A, Panagiotidou S, Pradhan-Nabzdyk L, Theoharides TC, Veves A. Mast Cells Regulate Wound Healing in Diabetes. Diabetes. 2016 07; 65(7):2006-19.
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Coulon SJ, Velasco-Gonzalez C, Scribner R, Park CL, Gomez R, Vargas A, Stender S, Zabaleta J, Clesi P, Chalew SA, Hempe JM. Racial differences in neighborhood disadvantage, inflammation and metabolic control in black and white pediatric type 1 diabetes patients. Pediatr Diabetes. 2017 03; 18(2):120-127.
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Legaspi R, Narciso P. Euglycemic Diabetic Ketoacidosis Due to Gastroparesis, A Local Experience. J Ark Med Soc. 2015 Sep; 112(5):62-3.
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Adamski J, Kinard T, Ipe T, Cooling L. Extracorporeal photopheresis for the treatment of autoimmune diseases. Transfus Apher Sci. 2015 Apr; 52(2):171-82.
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Maraka S, Kudva YC, Kellogg TA, Collazo-Clavell ML, Mundi MS. Bariatric surgery and diabetes: Implications of type 1 versus insulin-requiring type 2. Obesity (Silver Spring). 2015 Mar; 23(3):552-7.
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Samyn MM, Dholakia R, Wang H, Co-Vu J, Yan K, Widlansky ME, LaDisa JF, Simpson P, Alemzadeh R. Cardiovascular magnetic resonance imaging-based computational fluid dynamics/fluid-structure interaction pilot study to detect early vascular changes in pediatric patients with type 1 diabetes. Pediatr Cardiol. 2015 Apr; 36(4):851-61.
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Davis SM, Maddux AB, Alonso GT, Okada CR, Mourani PM, Maahs DM. Profound hypokalemia associated with severe diabetic ketoacidosis. Pediatr Diabetes. 2016 Feb; 17(1):61-5.
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Bhat DK, Kanga U, Kumar N, Agrawal RP, Mourya M, Kalaivani M, Kaur T, Mehra NK. The Raikas - a unique combination of high prevalence of type 1 diabetes susceptibility genes and near zero incidence of the disease. Hum Immunol. 2014 Dec; 75(12):1252-8.
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Bajaj G, Nicholas R, Pandey T, Montgomery C, Jambhekar K, Ram R. MR imaging findings in diabetic muscle infarction. J Ark Med Soc. 2014 Oct; 111(5):91-3.
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Guo X, Wang L, Velazquez H, Safirstein R, Desir GV. Renalase: its role as a cytokine, and an update on its association with type 1 diabetes and ischemic stroke. Curr Opin Nephrol Hypertens. 2014 Sep; 23(5):513-8.
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Huggins JT, Karakala N, Campbell R, Kummerfeldt C, Nestor J, Pastis NJ, Doelken P. A 37-year-old woman with diabetes mellitus, systemic hypertension, and chronic kidney disease admitted with multifocal pneumonia and empyema. Chest. 2014 Aug; 146(2):e41-e46.
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Harman DJ, Kaye PV, Harris R, Suzuki A, Gazis A, Aithal GP. Prevalence and natural history of histologically proven chronic liver disease in a longitudinal cohort of patients with type 1 diabetes. Hepatology. 2014 Jul; 60(1):158-68.
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