 Adipose Tissue, Brown
"Adipose Tissue, Brown" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thermogenic form of adipose tissue composed of BROWN ADIPOCYTES. It is found in newborns of many species including humans, and in hibernating mammals. Brown fat is richly vascularized, innervated, and densely packed with MITOCHONDRIA which can generate heat directly from the stored lipids.
| Descriptor ID |
D002001
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| MeSH Number(s) |
A10.165.114.322
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Adipose Tissue, Brown".
Below are MeSH descriptors whose meaning is more specific than "Adipose Tissue, Brown".
This graph shows the total number of publications written about "Adipose Tissue, Brown" by people in UAMS Profiles by year, and whether "Adipose Tissue, Brown" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2022 | 0 | 1 | 1 | | 2021 | 1 | 2 | 3 | | 2020 | 2 | 1 | 3 | | 2019 | 2 | 0 | 2 | | 2018 | 1 | 1 | 2 | | 2017 | 3 | 1 | 4 | | 2016 | 4 | 1 | 5 | | 2015 | 2 | 0 | 2 | | 2014 | 4 | 0 | 4 | | 2013 | 1 | 1 | 2 | | 2012 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Adipose Tissue, Brown" by people in Profiles over the past ten years.
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Pinho ACO, Santos D, Baldeiras I, Burgeiro A, Leal EC, Carvalho E. Mitochondrial respiration in thoracic perivascular adipose tissue of diabetic mice. J Endocrinol. 2022 09 01; 254(3):169-184.
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Girer NG, Rontoyanni VG, Joshi A, Patrikeev I, Murton AJ, Porter C, Motamedi M, Elferink CJ. Liver-Specific Nonviral Gene Delivery of Fibroblast Growth Factor 21 Protein Expression in Mice Regulates Body Mass and White/Brown Fat Respiration. J Pharmacol Exp Ther. 2021 08; 378(2):157-165.
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Blackburn ML, Wankhade UD, Ono-Moore KD, Chintapalli SV, Fox R, Rutkowsky JM, Willis BJ, Tolentino T, Lloyd KCK, Adams SH. On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice. Am J Physiol Endocrinol Metab. 2021 07 01; 321(1):E47-E62.
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Pilkington AC, Paz HA, Wankhade UD. Beige Adipose Tissue Identification and Marker Specificity-Overview. Front Endocrinol (Lausanne). 2021; 12:599134.
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Ono-Moore KD, Rutkowsky JM, Pearson NA, Williams DK, Grobe JL, Tolentino T, Lloyd KCK, Adams SH. Coupling of energy intake and energy expenditure across a temperature spectrum: impact of diet-induced obesity in mice. Am J Physiol Endocrinol Metab. 2020 09 01; 319(3):E472-E484.
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Bhattarai N, Rontoyanni VG, Ross E, Ogunbileje JO, Murton AJ, Porter C. Brown adipose tissue recruitment in a rodent model of severe burns. Burns. 2020 11; 46(7):1653-1659.
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Davidson CQ, Tharmalingam S, Niccoli S, Nemec-Bakk A, Khurana S, Murray A, Tai TC, Boreham DR, Khaper N, Lees SJ. Dose threshold for radiation induced fetal programming in a mouse model at 4 months of age: Hepatic expression of genes and proteins involved in glucose metabolism and glucose uptake in brown adipose tissue. PLoS One. 2020; 15(4):e0231650.
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Soni N, Ross AB, Scheers N, Nookaew I, Gabrielsson BG, Sandberg AS. The Omega-3 Fatty Acids EPA and DHA, as a Part of a Murine High-Fat Diet, Reduced Lipid Accumulation in Brown and White Adipose Tissues. Int J Mol Sci. 2019 Nov 24; 20(23).
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Girer NG, Carter D, Bhattarai N, Mustafa M, Denner L, Porter C, Elferink CJ. Inducible Loss of the Aryl Hydrocarbon Receptor Activates Perigonadal White Fat Respiration and Brown Fat Thermogenesis via Fibroblast Growth Factor 21. Int J Mol Sci. 2019 Feb 22; 20(4).
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Allan CM, Heizer PJ, Tu Y, Sandoval NP, Jung RS, Morales JE, Sajti E, Troutman TD, Saunders TL, Cusanovich DA, Beigneux AP, Romanoski CE, Fong LG, Young SG. An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner. J Lipid Res. 2019 04; 60(4):869-879.
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Bagchi RA, Ferguson BS, Stratton MS, Hu T, Cavasin MA, Sun L, Lin YH, Liu D, Londono P, Song K, Pino MF, Sparks LM, Smith SR, Scherer PE, Collins S, Seto E, McKinsey TA. HDAC11 suppresses the thermogenic program of adipose tissue via BRD2. JCI Insight. 2018 08 09; 3(15).
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Wankhade UD, Lee JH, Dagur PK, Yadav H, Shen M, Chen W, Kulkarni AB, McCoy JP, Finkel T, Cypess AM, Rane SG. TGF-ß receptor 1 regulates progenitors that promote browning of white fat. Mol Metab. 2018 10; 16:160-171.
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Chondronikola M, Porter C, Malagaris I, Nella AA, Sidossis LS. Brown adipose tissue is associated with systemic concentrations of peptides secreted from the gastrointestinal system and involved in appetite regulation. Eur J Endocrinol. 2017 Jul; 177(1):33-40.
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Porter C. Quantification of UCP1 function in human brown adipose tissue. Adipocyte. 2017 04 03; 6(2):167-174.
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Coker RH, Weaver AN, Coker MS, Murphy CJ, Gunga HC, Steinach M. Metabolic Responses to the Yukon Arctic Ultra: Longest and Coldest in the World. Med Sci Sports Exerc. 2017 02; 49(2):357-362.
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Chondronikola M, Porter C, Ogunbileje JO, Sidossis LS. Identification and Quantification of Human Brown Adipose Tissue. Methods Mol Biol. 2017; 1566:159-176.
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Wankhade UD, Shen M, Yadav H, Thakali KM. Novel Browning Agents, Mechanisms, and Therapeutic Potentials of Brown Adipose Tissue. Biomed Res Int. 2016; 2016:2365609.
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García-Casarrubios E, de Moura C, Arroba AI, Pescador N, Calderon-Dominguez M, Garcia L, Herrero L, Serra D, Cadenas S, Reis F, Carvalho E, Obregon MJ, Valverde ÁM. Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes. Biochim Biophys Acta. 2016 12; 1861(12 Pt A):1929-1941.
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Porter C, Herndon DN, Chondronikola M, Chao T, Annamalai P, Bhattarai N, Saraf MK, Capek KD, Reidy PT, Daquinag AC, Kolonin MG, Rasmussen BB, Borsheim E, Toliver-Kinsky T, Sidossis LS. Human and Mouse Brown Adipose Tissue Mitochondria Have Comparable UCP1 Function. Cell Metab. 2016 08 09; 24(2):246-55.
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Ramage LE, Akyol M, Fletcher AM, Forsythe J, Nixon M, Carter RN, van Beek EJ, Morton NM, Walker BR, Stimson RH. Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation. Cell Metab. 2016 07 12; 24(1):130-41.
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Chondronikola M, Volpi E, Børsheim E, Porter C, Saraf MK, Annamalai P, Yfanti C, Chao T, Wong D, Shinoda K, Labbe SM, Hurren NM, Cesani F, Kajimura S, Sidossis LS. Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans. Cell Metab. 2016 06 14; 23(6):1200-1206.
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Sidossis LS, Porter C, Saraf MK, Børsheim E, Radhakrishnan RS, Chao T, Ali A, Chondronikola M, Mlcak R, Finnerty CC, Hawkins HK, Toliver-Kinsky T, Herndon DN. Browning of Subcutaneous White Adipose Tissue in Humans after Severe Adrenergic Stress. Cell Metab. 2015 Aug 04; 22(2):219-27.
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Chondronikola M, Porter C, Lidell ME, Sidossis LS. Response to comment on Chondronikola et al. Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans. Diabetes 2014;63:4089-4099. Diabetes. 2015 Jun; 64(6):e14-5.
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Chondronikola M, Annamalai P, Chao T, Porter C, Saraf MK, Cesani F, Sidossis LS. A percutaneous needle biopsy technique for sampling the supraclavicular brown adipose tissue depot of humans. Int J Obes (Lond). 2015 Oct; 39(10):1561-4.
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Porter C, Malagaris I, Sidossis LS. Is the heat surrounding adipose tissue mitochondria warranted? Curr Opin Clin Nutr Metab Care. 2014 Nov; 17(6):503-8.
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Chondronikola M, Volpi E, Børsheim E, Porter C, Annamalai P, Enerbäck S, Lidell ME, Saraf MK, Labbe SM, Hurren NM, Yfanti C, Chao T, Andersen CR, Cesani F, Hawkins H, Sidossis LS. Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans. Diabetes. 2014 Dec; 63(12):4089-99.
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Petruzzelli M, Schweiger M, Schreiber R, Campos-Olivas R, Tsoli M, Allen J, Swarbrick M, Rose-John S, Rincon M, Robertson G, Zechner R, Wagner EF. A switch from white to brown fat increases energy expenditure in cancer-associated cachexia. Cell Metab. 2014 Sep 02; 20(3):433-47.
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Chau YY, Bandiera R, Serrels A, Martínez-Estrada OM, Qing W, Lee M, Slight J, Thornburn A, Berry R, McHaffie S, Stimson RH, Walker BR, Chapuli RM, Schedl A, Hastie N. Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source. Nat Cell Biol. 2014 Apr; 16(4):367-75.
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Hussain A, Nookaew I, Khoomrung S, Andersson L, Larsson I, Hulthén L, Jansson N, Jakubowicz R, Nilsson S, Sandberg AS, Nielsen J, Holmäng A. A maternal diet of fatty fish reduces body fat of offspring compared with a maternal diet of beef and a post-weaning diet of fish improves insulin sensitivity and lipid profile in adult C57BL/6 male mice. Acta Physiol (Oxf). 2013 Nov; 209(3):220-34.
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