 Vitamin E
"Vitamin E" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.
| Descriptor ID |
D014810
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| MeSH Number(s) |
D03.438.150.909 D03.830.219.909
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Vitamin E".
Below are MeSH descriptors whose meaning is more specific than "Vitamin E".
This graph shows the total number of publications written about "Vitamin E" by people in UAMS Profiles by year, and whether "Vitamin E" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 0 | 1 | | 2021 | 1 | 1 | 2 | | 2020 | 2 | 2 | 4 | | 2019 | 2 | 2 | 4 | | 2018 | 3 | 0 | 3 | | 2016 | 6 | 0 | 6 | | 2015 | 1 | 0 | 1 | | 2014 | 4 | 0 | 4 | | 2013 | 3 | 0 | 3 | | 2012 | 1 | 1 | 2 | | 2011 | 2 | 0 | 2 | | 2010 | 3 | 1 | 4 | | 2009 | 2 | 0 | 2 | | 2008 | 0 | 1 | 1 | | 2007 | 1 | 1 | 2 | | 2006 | 1 | 1 | 2 | | 2003 | 2 | 0 | 2 | | 2002 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 1998 | 2 | 0 | 2 | | 1997 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Vitamin E" by people in Profiles over the past ten years.
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Garg S, Garg TK, Wise SY, Fatanmi OO, Miousse IR, Savenka AV, Basnakian AG, Singh VK, Hauer-Jensen M. Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate. Int J Mol Sci. 2022 Apr 22; 23(9).
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Nowak G, Megyesi J. ?-Tocotrienol Protects against Mitochondrial Dysfunction, Energy Deficits, Morphological Damage, and Decreases in Renal Functions after Renal Ischemia. Int J Mol Sci. 2021 Nov 24; 22(23).
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Nemec-Bakk AS, Sridharan V, Landes RD, Singh P, Cao M, Seawright JW, Liu X, Zheng G, Dominic P, Pathak R, Boerma M. Mitigation of late cardiovascular effects of oxygen ion radiation by ?-tocotrienol in a mouse model. Life Sci Space Res (Amst). 2021 Nov; 31:43-50.
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Gujarathi S, Zafar MK, Liu X, Eoff RL, Zheng G. A Facile Semisynthesis and Evaluation of Garcinoic Acid and Its Analogs for the Inhibition of Human DNA Polymerase ß. Molecules. 2020 Dec 11; 25(24).
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Chan D, Meister ML, Madhani CR, Elfakhani M, Yount ST, Ji X, Feresin RG, Wanders D, Mo H. Synergistic Impact of Xanthorrhizol and d-d-Tocotrienol on the Proliferation of Murine B16 Melanoma Cells and Human DU145 Prostate Carcinoma Cells. Nutr Cancer. 2021; 73(9):1746-1757.
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Liu X, Gao Z, Fu Q, Song L, Zhang P, Zhang X, Hendrickson H, Crooks PA, Zhou D, Zheng G. Deuteration of the farnesyl terminal methyl groups of d-tocotrienol and its effects on the metabolic stability and ability of inducing G-CSF production. Bioorg Med Chem. 2020 06 01; 28(11):115498.
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Liu X, Poddar S, Song L, Hendrickson H, Zhang X, Yuan Y, Zhou D, Zheng G. Synthesis and Liver Microsomal Metabolic Stability Studies of a Fluorine-Substituted d-Tocotrienol Derivative. ChemMedChem. 2020 03 18; 15(6):506-516.
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Pathak R, Kumar VP, Hauer-Jensen M, Ghosh SP. Enhanced Survival in Mice Exposed to Ionizing Radiation by Combination of Gamma-Tocotrienol and Simvastatin. Mil Med. 2019 03 01; 184(Suppl 1):644-651.
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Pathak R, Shah SK, Hauer-Jensen M. Therapeutic potential of natural plant products and their metabolites in preventing radiation enteropathy resulting from abdominal or pelvic irradiation. Int J Radiat Biol. 2019 04; 95(4):493-505.
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Aykin-Burns N, Pathak R, Boerma M, Kim T, Hauer-Jensen M. Utilization of Vitamin E Analogs to Protect Normal Tissues While Enhancing Antitumor Effects. Semin Radiat Oncol. 2019 01; 29(1):55-61.
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Ortiz D, Ferruzzi MG. Identification and Quantification of Carotenoids and Tocochromanols in Sorghum Grain by High-Performance Liquid Chromatography. Methods Mol Biol. 2019; 1931:141-151.
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Abraham A, Kattoor AJ, Saldeen T, Mehta JL. Vitamin E and its anticancer effects. Crit Rev Food Sci Nutr. 2019; 59(17):2831-2838.
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Cheema AK, Byrum SD, Sharma NK, Altadill T, Kumar VP, Biswas S, Balgley BM, Hauer-Jensen M, Tackett AJ, Ghosh SP. Proteomic Changes in Mouse Spleen after Radiation-Induced Injury and its Modulation by Gamma-Tocotrienol. Radiat Res. 2018 11; 190(5):449-463.
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Pourafshar S, Johnson SA, Keshavarz B, Feresin RG, Khalil DA, Chai SC, Arjmandi BH. The effects of supplemental vitamin E on hematological parameters in a rat model of ovarian hormone deficiency. Menopause. 2018 03; 25(3):336-342.
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Pathak R, Ghosh SP, Zhou D, Hauer-Jensen M. The Vitamin E Analog Gamma-Tocotrienol (GT3) and Statins Synergistically Up-Regulate Endothelial Thrombomodulin (TM). Int J Mol Sci. 2016 Nov 18; 17(11).
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Kim JE, Ferruzzi MG, Campbell WW. Egg Consumption Increases Vitamin E Absorption from Co-Consumed Raw Mixed Vegetables in Healthy Young Men. J Nutr. 2016 Nov; 146(11):2199-2205.
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Pathak R, Bachri A, Ghosh SP, Koturbash I, Boerma M, Binz RK, Sawyer JR, Hauer-Jensen M. The Vitamin E Analog Gamma-Tocotrienol (GT3) Suppresses Radiation-Induced Cytogenetic Damage. Pharm Res. 2016 09; 33(9):2117-25.
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Singh VK, Hauer-Jensen M. ?-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status. Int J Mol Sci. 2016 May 03; 17(5).
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Johnson SA, Feresin RG, Soung do Y, Elam ML, Arjmandi BH. Vitamin E suppresses ex vivo osteoclastogenesis in ovariectomized rats. Food Funct. 2016 Mar; 7(3):1628-33.
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Singh VK, Kulkarni S, Fatanmi OO, Wise SY, Newman VL, Romaine PL, Hendrickson H, Gulani J, Ghosh SP, Kumar KS, Hauer-Jensen M. Radioprotective Efficacy of Gamma-Tocotrienol in Nonhuman Primates. Radiat Res. 2016 Mar; 185(3):285-98.
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Guy C, Suzuki A, Abdelmalek M, Burchette J, Diehl AM. Reply: To PMID 24849310. Hepatology. 2015 May; 61(5):1770-1.
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Paulsen G, Hamarsland H, Cumming KT, Johansen RE, Hulmi JJ, Børsheim E, Wiig H, Garthe I, Raastad T. Vitamin C and E supplementation alters protein signalling after a strength training session, but not muscle growth during 10 weeks of training. J Physiol. 2014 Dec 15; 592(24):5391-408.
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Guy CD, Suzuki A, Abdelmalek MF, Burchette JL, Diehl AM. Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity. Hepatology. 2015 Jan; 61(1):98-107.
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Deng L, Ding Y, Peng Y, Wu Y, Fan J, Li W, Yang R, Yang M, Fu Q. ?-Tocotrienol protects against ovariectomy-induced bone loss via mevalonate pathway as HMG-CoA reductase inhibitor. Bone. 2014 Oct; 67:200-7.
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Deng L, Peng Y, Wu Y, Yang M, Ding Y, Chen Q, Fu Q. Tissue distribution of emulsified ?-tocotrienol and its long-term biological effects after subcutaneous administration. Lipids Health Dis. 2014 Apr 09; 13:66.
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Compadre CM, Singh A, Thakkar S, Zheng G, Breen PJ, Ghosh S, Kiaei M, Boerma M, Varughese KI, Hauer-Jensen M. Molecular dynamics guided design of tocoflexol: a new radioprotectant tocotrienol with enhanced bioavailability. Drug Dev Res. 2014 Feb; 75(1):10-22.
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Suman S, Datta K, Chakraborty K, Kulkarni SS, Doiron K, Fornace AJ, Sree Kumar K, Hauer-Jensen M, Ghosh SP. Gamma tocotrienol, a potent radioprotector, preferentially upregulates expression of anti-apoptotic genes to promote intestinal cell survival. Food Chem Toxicol. 2013 Oct; 60:488-96.
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Ray S, Kulkarni SS, Chakraborty K, Pessu R, Hauer-Jensen M, Kumar KS, Ghosh SP. Mobilization of progenitor cells into peripheral blood by gamma-tocotrienol: a promising radiation countermeasure. Int Immunopharmacol. 2013 Mar; 15(3):557-64.
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