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Shengyu Mu

TitleAssistant Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPharmacology & Toxicology, College of Medicine
DivisionPharmacology Cardiovascular
AddressGB 117 VA Little Rock
325 S. Elm St.
Mail Slot # 611
Little Rock AR 72205
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    Collapse Research 
    Collapse research activities and funding
    R01HL146713     (MU, SHENGYU)Apr 1, 2019 - Mar 31, 2024
    NIH/Nat. Heart, Lung & Blood Institute
    T cell homing to the kidney contributes to salt retention and blood pressure regulation
    Role: Principal Investigator

    15BGIA25730047     (MU, SHENGYU)Jul 1, 2015 - Jun 30, 2017
    American Heart Association (SouthWest Affiliate)
    Role of Immune Cells in kidney in the Development of Salt-Sensitive Hypertension
    Role: Principal Investigator

    P20GM109005     (BOERMA, MARJAN)Jun 24, 2015 - May 31, 2025
    Center for Studies of Host Response to Cancer Therapy
    Role: Co-Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Shoeib AM, Yarbrough AL, Ford BM, Franks LN, Urbaniak A, Hensley LL, Benson LN, Mu S, Radominska-Pandya A, Prather PL. Characterization of cannabinoid receptors expressed in Ewing sarcoma TC-71 and A-673 cells as potential targets for anti-cancer drug development. Life Sci. 2021 Nov 15; 285:119993. PMID: 34592231.
      View in: PubMed
    2. Van S, Pal S, Garner BR, Steed K, Sridharan V, Mu S, Rusch NJ, Stolarz AJ. Dantrolene Prevents the Lymphostasis Caused by Doxorubicin in the Rat Mesenteric Circulation. Front Pharmacol. 2021; 12:727526. PMID: 34483938.
      View in: PubMed
    3. Xiong Y, Chang Y, Hao J, Zhang C, Yang F, Wang Z, Liu Y, Wang X, Mu S, Xu Q. Eplerenone Attenuates Fibrosis in the Contralateral Kidney of UUO Rats by Preventing Macrophage-to-Myofibroblast Transition. Front Pharmacol. 2021; 12:620433. PMID: 33716747.
      View in: PubMed
    4. Garner BR, Stolarz AJ, Stuckey D, Sarimollaoglu M, Liu Y, Palade PT, Rusch NJ, Mu S. KATP Channel Openers Inhibit Lymphatic Contractions and Lymph Flow as a Possible Mechanism of Peripheral Edema. J Pharmacol Exp Ther. 2021 01; 376(1):40-50. PMID: 33100270.
      View in: PubMed
    5. Dai L, Chen J, Lin Z, Wang Z, Mu S, Qin Z. Targeting Sphingosine Kinase by ABC294640 against Diffuse Intrinsic Pontine Glioma (DIPG). J Cancer. 2020; 11(16):4683-4691. PMID: 32626514.
      View in: PubMed
    6. Cozart MA, Phelan KD, Wu H, Mu S, Birnbaumer L, Rusch NJ, Zheng F. Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus. Sci Rep. 2020 01 21; 10(1):812. PMID: 31964991.
      View in: PubMed
    7. Zheng F, Mu S, Rusch NJ. Leptin Activates Trpm7 Channels in the Carotid Body As a Mechanism of Obesity-Related Hypertension. Circ Res. 2019 11 08; 125(11):1003-1005. PMID: 31697634.
      View in: PubMed
    8. Mu S, Fantegrossi WE, Rusch NJ. Cocaine-Responsive miRNA and Blood Pressure Elevation. Hypertension. 2018 04; 71(4):561-562. PMID: 29483229.
      View in: PubMed
    9. Sims CR, Singh SP, Mu S, Gokden N, Zakaria D, Nguyen TC, Mayeux PR. Rolipram Improves Outcome in a Rat Model of Infant Sepsis-Induced Cardiorenal Syndrome. Front Pharmacol. 2017; 8:237. PMID: 28515693.
      View in: PubMed
    10. Liu Y, Rafferty TM, Rhee SW, Webber JS, Song L, Ko B, Hoover RS, He B, Mu S. CD8+ T cells stimulate Na-Cl co-transporter NCC in distal convoluted tubules leading to salt-sensitive hypertension. Nat Commun. 2017 01 09; 8:14037. PMID: 28067240.
      View in: PubMed
    11. Jimbo R, Kawakami-Mori F, Mu S, Hirohama D, Majtan B, Shimizu Y, Yatomi Y, Fukumoto S, Fujita T, Shimosawa T. Fibroblast growth factor 23 accelerates phosphate-induced vascular calcification in the absence of Klotho deficiency. Kidney Int. 2014 May; 85(5):1103-11. PMID: 24088960.
      View in: PubMed
    12. Ogura S, Shimosawa T, Mu S, Sonobe T, Kawakami-Mori F, Wang H, Uetake Y, Yoshida K, Yatomi Y, Shirai M, Fujita T. Oxidative stress augments pulmonary hypertension in chronically hypoxic mice overexpressing the oxidized LDL receptor. . 2013 Jul 15; 305(2):H155-62. PMID: 23686713.
      View in: PubMed
    13. Shibata S, Mu S, Kawarazaki H, Muraoka K, Ishizawa K, Yoshida S, Kawarazaki W, Takeuchi M, Ayuzawa N, Miyoshi J, Takai Y, Ishikawa A, Shimosawa T, Ando K, Nagase M, Fujita T. Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway. J Clin Invest. 2011 Aug; 121(8):3233-43. PMID: 21765214.
      View in: PubMed
    14. Mu S, Shimosawa T, Ogura S, Wang H, Uetake Y, Kawakami-Mori F, Marumo T, Yatomi Y, Geller DS, Tanaka H, Fujita T. Epigenetic modulation of the renal ß-adrenergic-WNK4 pathway in salt-sensitive hypertension. Nat Med. 2011 May; 17(5):573-80. PMID: 21499270.
      View in: PubMed
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