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Receptors, LDL

"Receptors, LDL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.


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This graph shows the total number of publications written about "Receptors, LDL" by people in UAMS Profiles by year, and whether "Receptors, LDL" was a major or minor topic of these publications.
Bar chart showing 47 publications over 18 distinct years, with a maximum of 12 publications in 2003
To see the data from this visualization as text, click here.