 Homocysteine
"Homocysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiol-containing amino acid formed by a demethylation of METHIONINE.
| Descriptor ID |
D006710
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| MeSH Number(s) |
D02.886.030.498 D12.125.166.498
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| Concept/Terms |
Homocysteine- Homocysteine
- 2-amino-4-mercaptobutyric acid
- 2 amino 4 mercaptobutyric acid
- Homocysteine, L-Isomer
- Homocysteine, L Isomer
- L-Isomer Homocysteine
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Below are MeSH descriptors whose meaning is more general than "Homocysteine".
Below are MeSH descriptors whose meaning is more specific than "Homocysteine".
This graph shows the total number of publications written about "Homocysteine" by people in UAMS Profiles by year, and whether "Homocysteine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 | | 2014 | 0 | 2 | 2 | | 2012 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2008 | 2 | 4 | 6 | | 2007 | 2 | 0 | 2 | | 2006 | 4 | 0 | 4 | | 2005 | 4 | 3 | 7 | | 2004 | 6 | 4 | 10 | | 2003 | 2 | 0 | 2 | | 2002 | 2 | 1 | 3 | | 2001 | 1 | 2 | 3 | | 2000 | 2 | 0 | 2 | | 1999 | 0 | 2 | 2 | | 1998 | 2 | 1 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Homocysteine" by people in Profiles over the past ten years.
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Tripathi M, Singh BK, Zhou J, Tikno K, Widjaja A, Sandireddy R, Arul K, Abdul Ghani SAB, Bee GGB, Wong KA, Pei HJ, Shekeran SG, Sinha RA, Singh MK, Cook SA, Suzuki A, Lim TR, Cheah CC, Wang J, Xiao RP, Zhang X, Chow PKH, Yen PM. Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation. J Hepatol. 2022 11; 77(5):1246-1255.
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Wallis KF, Morehead LC, Bird JT, Byrum SD, Miousse IR. Differences in cell death in methionine versus cysteine depletion. Environ Mol Mutagen. 2021 03; 62(3):216-226.
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Ligthart-Melis GC, Engelen MPKJ, Simbo SY, Ten Have GAM, Thaden JJ, Cynober L, Deutz NEP. Metabolic Consequences of Supplemented Methionine in a Clinical Context. J Nutr. 2020 10 01; 150(Suppl 1):2538S-2547S.
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Deutz NE, Simbo SY, Ligthart-Melis GC, Cynober L, Smriga M, Engelen MP. Tolerance to increased supplemented dietary intakes of methionine in healthy older adults. Am J Clin Nutr. 2017 Aug; 106(2):675-683.
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Wong D, Tortorelli S, Bishop L, Sellars EA, Schimmenti LA, Gallant N, Prada CE, Hopkin RJ, Leslie ND, Berry SA, Rosenblatt DS, Fair AL, Matern D, Raymond K, Oglesbee D, Rinaldo P, Gavrilov D. Outcomes of four patients with homocysteine remethylation disorders detected by newborn screening. Genet Med. 2016 Feb; 18(2):162-7.
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Tang X, Cleves MA, Nick TG, Li M, MacLeod SL, Erickson SW, Li J, Shaw GM, Mosley BS, Hobbs CA. Obstructive heart defects associated with candidate genes, maternal obesity, and folic acid supplementation. Am J Med Genet A. 2015 Jun; 167(6):1231-42.
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Aissa AF, Tryndyak V, de Conti A, Melnyk S, Gomes TD, Bianchi ML, James SJ, Beland FA, Antunes LM, Pogribny IP. Effect of methionine-deficient and methionine-supplemented diets on the hepatic one-carbon and lipid metabolism in mice. Mol Nutr Food Res. 2014 Jul; 58(7):1502-12.
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Hobbs CA, Cleves MA, Macleod SL, Erickson SW, Tang X, Li J, Li M, Nick T, Malik S. Conotruncal heart defects and common variants in maternal and fetal genes in folate, homocysteine, and transsulfuration pathways. Birth Defects Res A Clin Mol Teratol. 2014 Feb; 100(2):116-26.
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