 Folic Acid
"Folic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
| Descriptor ID |
D005492
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| MeSH Number(s) |
D03.438.733.631.400
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| Concept/Terms |
Folic Acid- Folic Acid
- Vitamin M
- Pteroylglutamic Acid
- Vitamin B9
- B9, Vitamin
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Below are MeSH descriptors whose meaning is more general than "Folic Acid".
Below are MeSH descriptors whose meaning is more specific than "Folic Acid".
This graph shows the total number of publications written about "Folic Acid" by people in UAMS Profiles by year, and whether "Folic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2023 | 1 | 3 | 4 | | 2022 | 1 | 4 | 5 | | 2020 | 2 | 1 | 3 | | 2019 | 0 | 1 | 1 | | 2017 | 1 | 3 | 4 | | 2016 | 0 | 1 | 1 | | 2015 | 1 | 1 | 2 | | 2014 | 2 | 0 | 2 | | 2013 | 1 | 1 | 2 | | 2012 | 3 | 0 | 3 | | 2011 | 5 | 2 | 7 | | 2010 | 1 | 1 | 2 | | 2009 | 0 | 1 | 1 | | 2008 | 3 | 0 | 3 | | 2007 | 2 | 0 | 2 | | 2006 | 3 | 0 | 3 | | 2005 | 3 | 3 | 6 | | 2004 | 4 | 1 | 5 | | 2003 | 2 | 1 | 3 | | 2002 | 2 | 3 | 5 | | 2001 | 2 | 1 | 3 | | 1999 | 1 | 0 | 1 | | 1998 | 1 | 1 | 2 | | 1997 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 |
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Below are the most recent publications written about "Folic Acid" by people in Profiles over the past ten years.
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Bascom JT, Stephens SB, Lupo PJ, Canfield MA, Kirby RS, Nestoridi E, Salemi JL, Mai CT, Nembhard WN, Forestieri NE, Romitti PA, St Louis AM, Agopian AJ. Scientific impact of the National Birth Defects Prevention Network multistate collaborative publications. Birth Defects Res. 2024 Jan; 116(1):e2225.
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Gandy K, Sapkota Y, Scoggins MA, Jacola LM, Koscik TR, Hudson MM, Pui CH, Krull KR, van der Plas E. Genetic variants, neurocognitive outcomes, and functional neuroimaging in survivors of childhood acute lymphoblastic leukemia. JNCI Cancer Spectr. 2023 07 03; 7(4).
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Shlobin NA, Ghotme K, Caceres A, Ocal E, Pattisapu JV, Rosseau G, Blount JP, Boop FA. Neurosurgeon-Led Advocacy for Folic Acid Fortification to Prevent Spina Bifida. World Neurosurg. 2023 04; 172:96-97.
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Webber DM, Li M, MacLeod SL, Tang X, Levy JW, Karim MA, Erickson SW, Hobbs CA. Gene-Folic Acid Interactions and Risk of Conotruncal Heart Defects: Results from the National Birth Defects Prevention Study. Genes (Basel). 2023 01 09; 14(1).
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Shlobin NA, Roach JT, Kancherla V, Caceres A, Ocal E, Ghotme KA, Lam S, Park KB, Rosseau G, Blount JP, Boop FA. The role of neurosurgeons in global public health: the case of folic acid fortification of staple foods to prevent spina bifida. J Neurosurg Pediatr. 2023 01 01; 31(1):8-15.
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Samanta D, Ramakrishnaiah R, Frye RE. Complex Heterozygous Polymerase Gamma Mutation and Cerebral Folate Deficiency in a Child with Refractory Partial Status. Neurol India. 2022 Sep-Oct; 70(5):2265-2267.
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Nagumalli SK, Willett RA, de Conti A, Tryndyak VP, Avigan MI, da Costa GG, Beland FA, Rusyn I, Pogribny IP. Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice. J Nutr Biochem. 2022 11; 109:109108.
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Tripathi M, Singh BK, Zhou J, Tikno K, Widjaja A, Sandireddy R, Arul K, Abdul Ghani SAB, Bee GGB, Wong KA, Pei HJ, Shekeran SG, Sinha RA, Singh MK, Cook SA, Suzuki A, Lim TR, Cheah CC, Wang J, Xiao RP, Zhang X, Chow PKH, Yen PM. Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation. J Hepatol. 2022 11; 77(5):1246-1255.
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Palmsten K, Suhl J, Conway KM, Kharbanda EO, Ailes EC, Cragan JD, Nestoridi E, Papadopoulos EA, Kerr SM, Young SG, DeStefano F, Romitti PA. Influenza vaccination during pregnancy and risk of selected major structural noncardiac birth defects, National Birth Defects Prevention Study 2006-2011. Pharmacoepidemiol Drug Saf. 2022 08; 31(8):851-862.
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Sahu RK, Xavier S, Chauss D, Wang L, Chew C, Taylor R, Stallcup WB, Ma JZ, Kazemian M, Afzali B, K?hl J, Portilla D. Folic acid-mediated fibrosis is driven by C5a receptor 1-mediated activation of kidney myeloid cells. Am J Physiol Renal Physiol. 2022 06 01; 322(6):F597-F610.
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Hollowood-Jones K, Adams JB, Coleman DM, Ramamoorthy S, Melnyk S, James SJ, Woodruff BK, Pollard EL, Snozek CL, Kruger U, Chuah J, Hahn J. Altered metabolism of mothers of young children with Autism Spectrum Disorder: a case control study. BMC Pediatr. 2020 12 14; 20(1):557.
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Tiwari AKM, Mahdi AA, Mishra S, Parveen H, Fatima G. Effect of iron and folate supplementation on Pb levels in pregnant anemic women: a prospective study. Free Radic Res. 2020 Sep; 54(8-9):662-669.
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Frye RE, Rossignol DA, Scahill L, McDougle CJ, Huberman H, Quadros EV. Treatment of Folate Metabolism Abnormalities in Autism Spectrum Disorder. Semin Pediatr Neurol. 2020 10; 35:100835.
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Xavier S, Sahu RK, Bontha SV, Mass V, Taylor RP, Megyesi J, Thielens NM, Portilla D. Complement C1r serine protease contributes to kidney fibrosis. Am J Physiol Renal Physiol. 2019 11 01; 317(5):F1293-F1304.
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Stingone JA, Luben TJ, Carmichael SL, Aylsworth AS, Botto LD, Correa A, Gilboa SM, Langlois PH, Nembhard WN, Richmond-Bryant J, Shaw GM, Olshan AF. Maternal Exposure to Nitrogen Dioxide, Intake of Methyl Nutrients, and Congenital Heart Defects in Offspring. Am J Epidemiol. 2017 Sep 15; 186(6):719-729.
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Galanzha EI, Weingold R, Nedosekin DA, Sarimollaoglu M, Nolan J, Harrington W, Kuchyanov AS, Parkhomenko RG, Watanabe F, Nima Z, Biris AS, Plekhanov AI, Stockman MI, Zharov VP. Spaser as a biological probe. Nat Commun. 2017 06 08; 8:15528.
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Howsmon DP, Kruger U, Melnyk S, James SJ, Hahn J. Classification and adaptive behavior prediction of children with autism spectrum disorder based upon multivariate data analysis of markers of oxidative stress and DNA methylation. PLoS Comput Biol. 2017 03; 13(3):e1005385.
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Xavier S, Sahu RK, Landes SG, Yu J, Taylor RP, Ayyadevara S, Megyesi J, Stallcup WB, Duffield JS, Reis ES, Lambris JD, Portilla D. Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis. Am J Physiol Renal Physiol. 2017 03 01; 312(3):F516-F532.
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Tryndyak VP, Han T, Fuscoe JC, Ross SA, Beland FA, Pogribny IP. Status of hepatic DNA methylome predetermines and modulates the severity of non-alcoholic fatty liver injury in mice. BMC Genomics. 2016 Apr 22; 17:298.
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Emmett SD, West KP. Nutrition and hearing loss: a neglected cause and global health burden. Am J Clin Nutr. 2015 Nov; 102(5):987-8.
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Tang X, Cleves MA, Nick TG, Li M, MacLeod SL, Erickson SW, Li J, Shaw GM, Mosley BS, Hobbs CA. Obstructive heart defects associated with candidate genes, maternal obesity, and folic acid supplementation. Am J Med Genet A. 2015 Jun; 167(6):1231-42.
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