 Carcinogenicity Tests
"Carcinogenicity Tests" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.
| Descriptor ID |
D015197
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| MeSH Number(s) |
E05.940.150
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| Concept/Terms |
Carcinogenicity Tests- Carcinogenicity Tests
- Carcinogenicity Test
- Test, Carcinogenicity
- Tests, Carcinogenicity
- Carcinogenesis Tests
- Carcinogenesis Test
- Test, Carcinogenesis
- Tests, Carcinogenesis
- Tumorigenicity Tests
- Test, Tumorigenicity
- Tests, Tumorigenicity
- Tumorigenicity Test
- Carcinogenic Potency Tests
- Carcinogenic Potency Test
- Potency Test, Carcinogenic
- Potency Tests, Carcinogenic
- Test, Carcinogenic Potency
- Tests, Carcinogenic Potency
- Carcinogen Tests
- Carcinogen Test
- Test, Carcinogen
- Tests, Carcinogen
- Carcinogenic Activity Tests
- Carcinogenic Activity Test
- Test, Carcinogenic Activity
- Tests, Carcinogenic Activity
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Below are MeSH descriptors whose meaning is more general than "Carcinogenicity Tests".
Below are MeSH descriptors whose meaning is more specific than "Carcinogenicity Tests".
This graph shows the total number of publications written about "Carcinogenicity Tests" by people in UAMS Profiles by year, and whether "Carcinogenicity Tests" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2016 | 1 | 2 | 3 | | 2014 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2005 | 1 | 2 | 3 | | 2004 | 1 | 0 | 1 | | 2003 | 3 | 3 | 6 | | 2000 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1996 | 3 | 0 | 3 | | 1995 | 1 | 3 | 4 | | 1994 | 0 | 1 | 1 | | 1991 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Carcinogenicity Tests" by people in Profiles over the past ten years.
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Corton JC, Mitchell CA, Auerbach S, Bushel P, Ellinger-Ziegelbauer H, Escobar PA, Froetschl R, Harrill AH, Johnson K, Klaunig JE, Pandiri AR, Podtelezhnikov AA, Rager JE, Tanis KQ, van der Laan JW, Vespa A, Yauk CL, Pettit SD, Sistare FD. A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies. Toxicol Sci. 2022 06 28; 188(1):4-16.
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Yauk CL, Harrill AH, Ellinger-Ziegelbauer H, van der Laan JW, Moggs J, Froetschl R, Sistare F, Pettit S. A cross-sector call to improve carcinogenicity risk assessment through use of genomic methodologies. Regul Toxicol Pharmacol. 2020 Feb; 110:104526.
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Nunes J, Martins IL, Charneira C, Pogribny IP, de Conti A, Beland FA, Marques MM, Jacob CC, Antunes AMM. New insights into the molecular mechanisms of chemical carcinogenesis: In vivo adduction of histone H2B by a reactive metabolite of the chemical carcinogen furan. Toxicol Lett. 2016 Dec 15; 264:106-113.
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Tryndyak V, de Conti A, Doerge DR, Olson GR, Beland FA, Pogribny IP. Furan-induced transcriptomic and gene-specific DNA methylation changes in the livers of Fischer 344 rats in a 2-year carcinogenicity study. Arch Toxicol. 2017 Mar; 91(3):1233-1243.
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Chappell G, Pogribny IP, Guyton KZ, Rusyn I. Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: A systematic literature review. Mutat Res Rev Mutat Res. 2016 Apr-Jun; 768:27-45.
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Marrone AK, Beland FA, Pogribny IP. Noncoding RNA response to xenobiotic exposure: an indicator of toxicity and carcinogenicity. Expert Opin Drug Metab Toxicol. 2014 Oct; 10(10):1409-22.
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