 DNA Gyrase
"DNA Gyrase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting two A and two B subunits. In the presence of ATP, gyrase is able to convert relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase.
| Descriptor ID |
D027081
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| MeSH Number(s) |
D08.811.399.403.741.149 D12.776.097.237
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "DNA Gyrase".
Below are MeSH descriptors whose meaning is more specific than "DNA Gyrase".
This graph shows the total number of publications written about "DNA Gyrase" by people in UAMS Profiles by year, and whether "DNA Gyrase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Gyrase" by people in Profiles over the past ten years.
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Tafoukt R, Leangapichart T, Hadjadj L, Bakour S, Diene SM, Rolain JM, Touati A. Characterisation of blaOXA-538, a new variant of blaOXA-48, in Shewanella xiamenensis isolated from river water in Algeria. J Glob Antimicrob Resist. 2018 06; 13:70-73.
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Avalos E, Catanzaro D, Catanzaro A, Ganiats T, Brodine S, Alcaraz J, Rodwell T. Frequency and geographic distribution of gyrA and gyrB mutations associated with fluoroquinolone resistance in clinical Mycobacterium tuberculosis isolates: a systematic review. PLoS One. 2015; 10(3):e0120470.
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Ajbani K, Lin SY, Rodrigues C, Nguyen D, Arroyo F, Kaping J, Jackson L, Garfein RS, Catanzaro D, Eisenach K, Victor TC, Crudu V, Gler MT, Ismail N, Desmond E, Catanzaro A, Rodwell TC. Evaluation of pyrosequencing for detecting extensively drug-resistant Mycobacterium tuberculosis among clinical isolates from four high-burden countries. Antimicrob Agents Chemother. 2015 Jan; 59(1):414-20.
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