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Jason Farrar

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPeds Pediatrics, College of Medicine
DivisionPeds Hematology
Address9-123 Cancer Institute
1120 Marshall Street
Mail Slot # 512-10
Little Rock AR 72202
Phone501-603-1224
ORCID ORCID Icon0000-0003-2148-5839 Additional info
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    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    K12TR004924     (ARTHUR, JOHN M.)Jul 1, 2024 - Jun 30, 2029
    NIH
    CTSA K12 Program at the University of Arkansas for Medical Sciences
    Role: Co-Principal Investigator
    P20GM121293     (BYRD, ALICIA K)Jul 1, 2022 - Jun 30, 2027
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Arkansas Children's Research Institute
    Role of HELB in the Replication Stress Response Dr. Tacketts COBRA through ACRI
    Role: Principal Investigator
    P20GM121293     (BYRD, ALICIA K)Jul 1, 2022 - Jun 30, 2024
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Arkansas Children's Research Institute
    Role of HELB in the Replication Stress Response Dr. Tacketts COBRA through ACRI
    Role: Principal Investigator
    GR039178     (FARRAR, JASON E)Jul 1, 2022 - Jun 30, 2023
    UAMS ACHRI Flow Through
    GR039178-Farrar-ACRI Proteogenomics Core
    Role: Principal Investigator
    GR034151     (FARRAR, JASON E)Feb 1, 2022 - Jan 31, 2023
    UAMS ACHRI Flow Through
    GR034151 Farrar ACHRI Mechanisms of Erythroid Remission in Diamond Blackfan Anemia (DBA)
    Role: Principal Investigator
    R01HL150194     (FARRAR, JASON ELI)Feb 15, 2020 - Jan 31, 2024
    NIH
    Mechanisms of Erythroid Remission in Diamond Blackfan Anemia (DBA)
    Role: Principal Investigator
    034032     (FARRAR, JASON E)Feb 15, 2020 - Jan 31, 2023
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    GR034024     (FARRAR, JASON E)Oct 1, 2019 - Jun 30, 2020
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    R01HD093461     (CHILDS, GWEN V;MACNICOL, ANGUS M ;MACNICOL, MELANIE C)Sep 1, 2018 - Jun 30, 2024
    NIH
    Control of pituitary cell plasticity through regulated mRNA translation
    Role: Co-Investigator
    ACRI # 039142     (FARRAR, JASON E)Jul 1, 2018 - Jun 30, 2020
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI # 039143     (FARRAR, JASON E)Apr 1, 2018 - Mar 31, 2019
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    5P20 GM121293-03     (FARRAR, JASON E)Jul 1, 2017 - Sep 30, 2019
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Arkansas Children's Hospital
    Tackett COBRE-SUBAward J Farrar Project 1 - Continuation - Continuation
    Role: Principal Investigator
    5P20GM121293     (FARRAR, JASON)Jul 1, 2017 - Sep 30, 2019
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Arkansas Children's Hospital
    Tackett COBRE-SUBAward J Farrar Project 1 - Continuation
    Role: Principal Investigator
    R01DK113776     (CHILDS, GWEN V)Apr 1, 2017 - Mar 31, 2021
    NIH
    Tropic Roles for Leptin in the Maturation of Somatotropes
    Role: Co-Investigator
    ACRI #037093     (FARRAR, JASON E)Nov 1, 2016 - Oct 31, 2018
    Arkansas Children's Research Institute
    Integrative Genomics in Pediatric AML
    Role: Principal Investigator
    ACRI#037093     (FARRAR, JASON E)Nov 1, 2016 - Oct 31, 2018
    Arkansas Children's Research Institute
    Integrative Genomics in Pediatric AML
    Role: Principal Investigator
    ACRI # 039704     (FARRAR, JASON E)Jul 1, 2016 - Jun 30, 2017
    UAMS ACHRI Flow Through
    Epigenomic Characterization of Pediatric AML
    Role: Principal Investigator
    ACRI#039704     (FARRAR, JASON E)Jul 1, 2016 - Jun 30, 2017
    UAMS ACHRI Flow Through
    Epigenomic Characterization of Pediatric AML
    Role: Principal Investigator
    0000856528     (FARRAR, JASON E)Jul 1, 2015 - Jun 30, 2018
    St. Baldrick's Foundation - Pass Through: Fred Hutchinson Cancer Research Center
    St. Baldrick's Subaward
    Role: Principal Investigator
    0000881186     (FARRAR, JASON E)Jul 1, 2015 - Jun 30, 2018
    St. Baldrick's Foundation - Pass Through: Fred Hutchinson Cancer Research Center
    St. Baldrick's Subaward
    Role: Principal Investigator
    0000914837     (FARRAR, JASON E)Jul 1, 2015 - Jun 30, 2018
    St. Baldrick's Foundation - Pass Through: Fred Hutchinson Cancer Research Center
    St. Baldrick's Subaward
    Role: Principal Investigator
    K08HL092224     (FARRAR, JASON ELI)Apr 26, 2009 - Mar 31, 2015
    NIH
    Functional Analysis of RPL35A Alterations in Diamond Blackfan Anemia
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Farrar JE, Stefanos SS, Cava L, Kiser TH, Mueller SW, Neumann R, Reynolds PM, Sherman DS, MacLaren R. Correlation Between Serum and CSF Concentrations of Midazolam and 1-Hydroxy-Midazolam in Critically Ill Neurosurgical Patients. Ann Pharmacother. 2024 Aug 20; 10600280241271130. PMID: 39164827.
      View in: PubMed
    2. Saad-Roy CM, Morris SE, Boots M, Baker RE, Lewis BL, Farrar J, Marathe MV, Graham AL, Levin SA, Wagner CE, Metcalf CJE, Grenfell BT. Impact of waning immunity against SARS-CoV-2 severity exacerbated by vaccine hesitancy. PLoS Comput Biol. 2024 Aug; 20(8):e1012211. PMID: 39102402.
      View in: PubMed
    3. Doan DT, Strebeck PV, Tran AD, Farrar JE, Appell LE, Modi AJ, Jefferson AA. Evaluation of recurrent and recalcitrant warts in a deaf adolescent male reveals GATA2 deficiency. J Allergy Clin Immunol Glob. 2024 Nov; 3(4):100313. PMID: 39221430.
      View in: PubMed
    4. Wlodarski MW, Vlachos A, Farrar JE, Da Costa LM, Kattamis A, Dianzani I, Belendez C, Unal S, Tamary H, Pasauliene R, Pospisilova D, de la Fuente J, Iskander D, Wolfe L, Liu JM, Shimamura A, Albrecht K, Lausen B, Bechensteen AG, Tedgard U, Puzik A, Quarello P, Ramenghi U, Bartels M, Hengartner H, Farah RA, Al Saleh M, Hamidieh AA, Yang W, Ito E, Kook H, Ovsyannikova G, Kager L, Gleizes PE, Dalle JH, Strahm B, Niemeyer CM, Lipton JM, Leblanc TM. Diagnosis, treatment, and surveillance of Diamond-Blackfan anaemia syndrome: international consensus statement. Lancet Haematol. 2024 May; 11(5):e368-e382. PMID: 38697731.
      View in: PubMed
    5. Abla O, Ries RE, Triche T, Gerbing RB, Hirsch B, Raimondi S, Cooper T, Farrar JE, Buteyn N, Harmon LM, Wen H, Deshpande AJ, Kolb EA, Gamis AS, Aplenc R, Alonzo T, Meshinchi S. Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia. Blood Adv. 2024 04 23; 8(8):2005-2017. PMID: 38306602.
      View in: PubMed
    6. Appell LE, Mack JM, Farrar JE, Roper SN, Savage MR, Pandey S, Crary SE. Acquired Hemophilia: A Rare Complication of Pediatric Idiopathic Multicentric Castleman Disease. Pediatrics. 2024 Apr 01; 153(4). PMID: 38511235.
      View in: PubMed
    7. Frett B, Stephens KE, Koss B, Melnyk S, Farrar J, Saha D, Roy Choudhury S. Enhancer-activated RET confers protection against oxidative stress to KMT2A-rearranged acute myeloid leukemia. Cancer Sci. 2024 Mar; 115(3):963-973. PMID: 38226414.
      View in: PubMed
    8. Bertrums EJM, Smith JL, Harmon L, Ries RE, Wang YJ, Alonzo TA, Menssen AJ, Chisholm KM, Leonti AR, Tarlock K, Ostronoff F, Pogosova-Agadjanyan EL, Kaspers GJL, Hasle H, Dworzak M, Walter C, Muhlegger N, Morerio C, Pardo L, Hirsch B, Raimondi S, Cooper TM, Aplenc R, Gamis AS, Kolb EA, Farrar JE, Stirewalt D, Ma X, Shaw TI, Furlan SN, Brodersen LE, Loken MR, Van den Heuvel-Eibrink MM, Zwaan CM, Triche TJ, Goemans BF, Meshinchi S. Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia. Haematologica. 2023 08 01; 108(8):2044-2058. PMID: 36815378.
      View in: PubMed
    9. Sun JM, Chow WY, Xu G, Hicks MJ, Nakka M, Shen J, Ng PKS, Taylor AM, Yu A, Farrar JE, Barkauskas DA, Gorlick R, Guidry Auvil JM, Gerhard D, Meltzer P, Guerra R, Man TK, Lau CC. The Role of FAS Receptor Methylation in Osteosarcoma Metastasis. Int J Mol Sci. 2023 Jul 29; 24(15). PMID: 37569529.
      View in: PubMed
    10. Farrar JE, Othus M, Wang YC, Alonzo TA, Meshinchi S. Reply to Z.R. McCaw et al. J Clin Oncol. 2023 09 20; 41(27):4447. PMID: 37390387.
      View in: PubMed
    11. Farrar JE, Smith JL, Othus M, Huang BJ, Wang YC, Ries R, Hylkema T, Pogosova-Agadjanyan EL, Challa S, Leonti A, Shaw TI, Triche TJ, Gamis AS, Aplenc R, Kolb EA, Ma X, Stirewalt DL, Alonzo TA, Meshinchi S. Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia. J Clin Oncol. 2023 06 01; 41(16):2949-2962. PMID: 36795987.
      View in: PubMed
    12. Huang BJ, Smith JL, Farrar JE, Wang YC, Umeda M, Ries RE, Leonti AR, Crowgey E, Furlan SN, Tarlock K, Armendariz M, Liu Y, Shaw TI, Wei L, Gerbing RB, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Rubnitz J, Ma J, Klco JM, Ma X, Alonzo TA, Triche T, Meshinchi S. Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia. Nat Commun. 2022 09 19; 13(1):5487. PMID: 36123353.
      View in: PubMed
    13. Hu Y, Caldwell KJ, Onciu M, Federico SM, Salek M, Lewis S, Lei S, Zhang J, Nichols KE, Takemoto CM, Triplett BM, Farrar JE, Rubnitz JE, Ribeiro RC, Wlodarski MW. CPX-351 induces remission in newly diagnosed pediatric secondary myeloid malignancies. Blood Adv. 2022 01 25; 6(2):521-527. PMID: 34710216.
      View in: PubMed
    14. Hecht A, Meyer JA, Behnert A, Wong E, Chehab F, Olshen A, Hechmer A, Aftandilian C, Bhat R, Choi SW, Chonat S, Farrar JE, Fluchel M, Frangoul H, Han JH, Kolb EA, Kuo DJ, MacMillan ML, Maese L, Maloney KW, Narendran A, Oshrine B, Schultz KR, Sulis ML, Van Mater D, Tasian SK, Hofmann WK, Loh ML, Stieglitz E. Molecular and phenotypic diversity of CBL-mutated juvenile myelomonocytic leukemia. Haematologica. 2022 01 01; 107(1):178-186. PMID: 33375775.
      View in: PubMed
    15. Huang BJ, Smith JL, Wang YC, Taghizadeh K, Leonti AR, Ries RE, Liu Y, Kolekar P, Tarlock K, Gerbing R, Crowgey E, Furlan SN, Shaw TI, Hagiwara K, Wei L, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Farrar JE, Triche T, Alonzo TA, Ma X, Meshinchi S. CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes. Blood Adv. 2021 12 14; 5(23):4963-4968. PMID: 34547772.
      View in: PubMed
    16. Bolouri H, Ries R, Pardo L, Hylkema T, Zhou W, Smith JL, Leonti A, Loken M, Farrar JE, Triche TJ, Meshinchi S. A B-cell developmental gene regulatory network is activated in infant AML. PLoS One. 2021; 16(11):e0259197. PMID: 34793513.
      View in: PubMed
    17. Douglass DP, Stine KC, Farrar JE. A Novel Germline TP53 Mutation in a Patient With Li-Fraumeni Syndrome: Resolving a Variant of Uncertain Significance. J Pediatr Hematol Oncol. 2021 Nov 01; 43(8):e1220-e1222. PMID: 33633026.
      View in: PubMed
    18. Gill PS, Yu FB, Porter-Gill PA, Boyanton BL, Allen JC, Farrar JE, Veerapandiyan A, Prodhan P, Bielamowicz KJ, Sellars E, Burrow A, Kennedy JL, Clothier JL, Becton DL, Rule D, Schaefer GB. Implementing Pharmacogenomics Testing: Single Center Experience at Arkansas Children's Hospital. J Pers Med. 2021 May 11; 11(5). PMID: 34064668.
      View in: PubMed
    19. Gianferante MD, Wlodarski MW, Atsidaftos E, Da Costa L, Delaporta P, Farrar JE, Goldman FD, Hussain M, Kattamis A, Leblanc T, Lipton JM, Niemeyer CM, Pospisilova D, Quarello P, Ramenghi U, Sankaran VG, Vlachos A, Volejnikova J, Alter BP, Savage SA, Giri N. Genotype-phenotype association and variant characterization in Diamond-Blackfan anemia caused by pathogenic variants in RPL35A. Haematologica. 2021 05 01; 106(5):1303-1310. PMID: 32241839.
      View in: PubMed
    20. Li J, Galbo PM, Gong W, Storey AJ, Tsai YH, Yu X, Ahn JH, Guo Y, Mackintosh SG, Edmondson RD, Byrum SD, Farrar JE, He S, Cai L, Jin J, Tackett AJ, Zheng D, Wang GG. ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism. Nat Commun. 2021 02 16; 12(1):1045. PMID: 33594072.
      View in: PubMed
    21. Vlachos A, Atsidaftos E, Lababidi ML, Muir E, Rogers ZR, Alhushki W, Bernstein J, Glader B, Gruner B, Hartung H, Knoll C, Loew T, Nalepa G, Narla A, Panigrahi AR, Sieff CA, Walkovich K, Farrar JE, Lipton JM. L-leucine improves anemia and growth in patients with transfusion-dependent Diamond-Blackfan anemia: Results from a multicenter pilot phase I/II study from the Diamond-Blackfan Anemia Registry. Pediatr Blood Cancer. 2020 12; 67(12):e28748. PMID: 33025707.
      View in: PubMed
    22. Smith JL, Ries RE, Hylkema T, Alonzo TA, Gerbing RB, Santaguida MT, Eidenschink Brodersen L, Pardo L, Cummings CL, Loeb KR, Le Q, Imren S, Leonti AR, Gamis AS, Aplenc R, Kolb EA, Farrar JE, Triche TJ, Nguyen C, Meerzaman D, Loken MR, Oehler VG, Bolouri H, Meshinchi S. Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study. Clin Cancer Res. 2020 02 01; 26(3):726-737. PMID: 31719049.
      View in: PubMed
    23. Bolouri H, Farrar JE, Triche T, Ries RE, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Zhang J, Ma X, Liu Y, Liu Y, Auvil JMG, Davidsen TM, Gesuwan P, Hermida LC, Salhia B, Capone S, Ramsingh G, Zwaan CM, Noort S, Piccolo SR, Kolb EA, Gamis AS, Smith MA, Gerhard DS, Meshinchi S. Publisher Correction: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions. Nat Med. 2019 Mar; 25(3):530. PMID: 30705421.
      View in: PubMed
    24. Vlachos A, Osorio DS, Atsidaftos E, Kang J, Lababidi ML, Seiden HS, Gruber D, Glader BE, Onel K, Farrar JE, Bodine DM, Aspesi A, Dianzani I, Ramenghi U, Ellis SR, Lipton JM. Increased Prevalence of Congenital Heart Disease in Children With Diamond Blackfan Anemia Suggests Unrecognized Diamond Blackfan Anemia as a Cause of Congenital Heart Disease in the General Population: A Report of the Diamond Blackfan Anemia Registry. Circ Genom Precis Med. 2018 05; 11(5):e002044. PMID: 29748317.
      View in: PubMed
    25. Bolouri H, Farrar JE, Triche T, Ries RE, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Zhang J, Ma X, Liu Y, Liu Y, Auvil JMG, Davidsen TM, Gesuwan P, Hermida LC, Salhia B, Capone S, Ramsingh G, Zwaan CM, Noort S, Piccolo SR, Kolb EA, Gamis AS, Smith MA, Gerhard DS, Meshinchi S. Erratum: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions. Nat Med. 2018 Apr 10; 24(4):526. PMID: 29634680.
      View in: PubMed
    26. Bolouri H, Farrar JE, Triche T, Ries RE, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Zhang J, Ma X, Liu Y, Liu Y, Auvil JMG, Davidsen TM, Gesuwan P, Hermida LC, Salhia B, Capone S, Ramsingh G, Zwaan CM, Noort S, Piccolo SR, Kolb EA, Gamis AS, Smith MA, Gerhard DS, Meshinchi S. The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions. Nat Med. 2018 01; 24(1):103-112. PMID: 29227476.
      View in: PubMed
    27. Gore L, Triche TJ, Farrar JE, Wai D, Legendre C, Gooden GC, Liang WS, Carpten J, Lee D, Alvaro F, Macy ME, Arndt C, Barnette P, Cooper T, Martin L, Narendran A, Pollard J, Meshinchi S, Boklan J, Arceci RJ, Salhia B. A multicenter, randomized study of decitabine as epigenetic priming with induction chemotherapy in children with AML. Clin Epigenetics. 2017; 9:108. PMID: 29034009.
      View in: PubMed
    28. Farrar JE, Neuberg D, Triche T, Bodine DM. Response: Making "perfect" the enemy of good. Blood. 2017 08 31; 130(9):1168-1169. PMID: 28754684.
      View in: PubMed
    29. O'Brien KA, Farrar JE, Vlachos A, Anderson SM, Tsujiura CA, Lichtenberg J, Blanc L, Atsidaftos E, Elkahloun A, An X, Ellis SR, Lipton JM, Bodine DM. Molecular convergence in ex vivo models of Diamond-Blackfan anemia. Blood. 2017 06 08; 129(23):3111-3120. PMID: 28377399.
      View in: PubMed
    30. Maxson JE, Ries RE, Wang YC, Gerbing RB, Kolb EA, Thompson SL, Guidry Auvil JM, Marra MA, Ma Y, Zong Z, Mungall AJ, Moore R, Long W, Gesuwan P, Davidsen TM, Hermida LC, Hughes SB, Farrar JE, Radich JP, Smith MA, Gerhard DS, Gamis AS, Alonzo TA, Meshinchi S. CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML. Blood. 2016 06 16; 127(24):3094-8. PMID: 27143256.
      View in: PubMed
    31. Farrar JE, Schuback HL, Ries RE, Wai D, Hampton OA, Trevino LR, Alonzo TA, Guidry Auvil JM, Davidsen TM, Gesuwan P, Hermida L, Muzny DM, Dewal N, Rustagi N, Lewis LR, Gamis AS, Wheeler DA, Smith MA, Gerhard DS, Meshinchi S. Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse. Cancer Res. 2016 04 15; 76(8):2197-205. PMID: 26941285.
      View in: PubMed
    32. Qin Y, Horby PW, Tsang TK, Chen E, Gao L, Ou J, Nguyen TH, Duong TN, Gasimov V, Feng L, Wu P, Jiang H, Ren X, Peng Z, Li S, Li M, Zheng J, Liu S, Hu S, Hong R, Farrar JJ, Leung GM, Gao GF, Cowling BJ, Yu H. Differences in the Epidemiology of Human Cases of Avian Influenza A(H7N9) and A(H5N1) Viruses Infection. Clin Infect Dis. 2015 Aug 15; 61(4):563-71. PMID: 25940354.
      View in: PubMed
    33. Farrar JE, Quarello P, Fisher R, O'Brien KA, Aspesi A, Parrella S, Henson AL, Seidel NE, Atsidaftos E, Prakash S, Bari S, Garelli E, Arceci RJ, Dianzani I, Ramenghi U, Vlachos A, Lipton JM, Bodine DM, Ellis SR. Exploiting pre-rRNA processing in Diamond Blackfan anemia gene discovery and diagnosis. Am J Hematol. 2014 Oct; 89(10):985-91. PMID: 25042156.
      View in: PubMed
    34. Ochs MF, Farrar JE, Considine M, Wei Y, Meshinchi S, Arceci RJ. Outlier Analysis and Top Scoring Pair for Integrated Data Analysis and Biomarker Discovery. IEEE/ACM Trans Comput Biol Bioinform. 2014 May-Jun; 11(3):520-32. PMID: 26356020.
      View in: PubMed
    35. Farrar JE. Diamond Blackfan anemia: a Cheshire cat of hematology. Pediatr Blood Cancer. 2014 Jul; 61(7):1154-5. PMID: 24634369.
      View in: PubMed
    36. Nguyen TH, Nguyen TH, Vu TT, Farrar J, Hoang TL, Dong TH, Ngoc Tran V, Phung KL, Wolbers M, Whitehead SS, Hibberd ML, Wills B, Simmons CP. Corticosteroids for dengue - why don't they work? PLoS Negl Trop Dis. 2013; 7(12):e2592. PMID: 24349598.
      View in: PubMed
    37. Vlachos A, Farrar JE, Atsidaftos E, Muir E, Narla A, Markello TC, Singh SA, Landowski M, Gazda HT, Blanc L, Liu JM, Ellis SR, Arceci RJ, Ebert BL, Bodine DM, Lipton JM. Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q- syndrome. Blood. 2013 Oct 03; 122(14):2487-90. PMID: 23943650.
      View in: PubMed
    38. Ochs MF, Farrar JE, Considine M, Wei Y, Meschinchi S, Arceci RJ. Outlier Gene Set Analysis Combined with Top Scoring Pair Provides Robust Biomarkers of Pathway Activity. 8th IAPR International Conference on Pattern Recognition in Bioinformatics. 2013.
    39. Vlachos A, Farrar JE, Atsidaftos E, Muir E, Markello TC, Singh S, Liu JM, Ellis SR, Arceci RJ, Bodine D, Lipton J. 5q Myelodysplastic Syndrome (MDS) Masquerading as Diamond Blackfan Anemia [Abstract]. 25th Annual Meeting of the American Society of Pediatric Hematology Oncology. 2012; 1074.
    40. Markello TC, Carlson-Donohoe H, Sincan M, Adams D, Bodine DM, Farrar JE, Vlachos A, Lipton JM, Auerbach AD, Ostrander EA, Chandrasekharappa SC, Boerkoel CF, Gahl WA. Sensitive quantification of mosaicism using high density SNP arrays and the cumulative distribution function. Mol Genet Metab. 2012 Apr; 105(4):665-71. PMID: 22277120.
      View in: PubMed
    41. Farrar JE, Vlachos A, Atsidaftos E, Carlson-Donohoe H, Markello TC, Arceci RJ, Ellis SR, Lipton JM, Bodine DM. Ribosomal protein gene deletions in Diamond-Blackfan anemia. Blood. 2011 Dec 22; 118(26):6943-51. PMID: 22045982.
      View in: PubMed
    42. Farrar JE, Dahl N. Untangling the phenotypic heterogeneity of Diamond Blackfan anemia. Semin Hematol. 2011 Apr; 48(2):124-35. PMID: 21435509.
      View in: PubMed
    43. Day JN, Hoang TN, Duong AV, Hong CT, Diep PT, Campbell JI, Sieu TP, Hien TT, Bui T, Boni MF, Lalloo DG, Carter D, Baker S, Farrar JJ. Most cases of cryptococcal meningitis in HIV-uninfected patients in Vietnam are due to a distinct amplified fragment length polymorphism-defined cluster of Cryptococcus neoformans var. grubii VN1. J Clin Microbiol. 2011 Feb; 49(2):658-64. PMID: 21159929.
      View in: PubMed
    44. Farrar JE, Vlachos A, Atsidaftos EA, Carlson-Donohoe H, Markello TC, Arceci RJ, Lipton JM, Bodine DM. SNP Array Genotyping Reveals Constitutional and Mosaic Losses of Ribosomal Protein Gene Regions In Patients with Diamond Blackfan Anemia without Ribosomal Protein Gene Mutations [Abstract]. American Society of Hematology Annual Meeting. 2010.
    45. Vlachos A, Farrar J, Atsidaftos E, Muir E, Markello TC, Singh S, Liu JM, Ellis S, Arceci RJ, Bodine DM, Lipton JM. 5q- Myelodysplastic Syndrome, In One of 23 Children Lacking a Known Ribosomal Gene Mutation, Masquerading as Diamond Blackfan Anemia (DBA) and Responding to Lenalidomide [Abstract]. American Society of Hematology Annual Meeting. 2010.
    46. Chau TT, Mai NH, Phu NH, Nghia HD, Chuong LV, Sinh DX, Duong VA, Diep PT, Campbell JI, Baker S, Hien TT, Lalloo DG, Farrar JJ, Day JN. A prospective descriptive study of cryptococcal meningitis in HIV uninfected patients in Vietnam - high prevalence of Cryptococcus neoformans var grubii in the absence of underlying disease. BMC Infect Dis. 2010 Jul 09; 10:199. PMID: 20618932.
      View in: PubMed
    47. Holt KE, Baker S, Dongol S, Basnyat B, Adhikari N, Thorson S, Pulickal AS, Song Y, Parkhill J, Farrar JJ, Murdoch DR, Kelly DF, Pollard AJ, Dougan G. High-throughput bacterial SNP typing identifies distinct clusters of Salmonella Typhi causing typhoid in Nepalese children. BMC Infect Dis. 2010 May 31; 10:144. PMID: 20509974.
      View in: PubMed
    48. Tricou V, Vu HT, Quynh NV, Nguyen CV, Tran HT, Farrar J, Wills B, Simmons CP. Comparison of two dengue NS1 rapid tests for sensitivity, specificity and relationship to viraemia and antibody responses. BMC Infect Dis. 2010 May 28; 10:142. PMID: 20509940.
      View in: PubMed
    49. Doherty L, Sheen MR, Vlachos A, Choesmel V, O'Donohue MF, Clinton C, Schneider HE, Sieff CA, Newburger PE, Ball SE, Niewiadomska E, Matysiak M, Glader B, Arceci RJ, Farrar JE, Atsidaftos E, Lipton JM, Gleizes PE, Gazda HT. Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia. Am J Hum Genet. 2010 Feb 12; 86(2):222-8. PMID: 20116044.
      View in: PubMed
    50. Moore JB, Farrar JE, Arceci RJ, Liu JM, Ellis SR. Distinct Ribosome Maturation Defects in Yeast Models for Diamond Blackfan Anemia and Shwachman Diamond Syndrome. Haematologica. 2010; 95(1):57-64.
    51. Noronha SA, Farrar JE, Alonzo TA, Gerbing RB, Lacayo NJ, Dahl GV, Ravindranath Y, Arceci RJ, Loeb DM. WT1 expression at diagnosis does not predict survival in pediatric AML: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2009 Dec; 53(6):1136-9. PMID: 19618455.
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    52. Heuston EF, Farrar JE, Triche T, Buckley J, Sorensen P, Reynolds P, Reaman G, Yegnasubramanian V, Arceci RA. Selective and Titratable Effects On AML Genome-wide Methylation Patterning, Transcription, and Clonogenicity Using Low Concentrations of 5-Aza-2’ Deoxycytidine [Abstract]. American Society of Hematology Annual Meeting. 2009.
    53. Moore JB, Farrar JE, Arceci RJ, Liu JM, Ellis SR. Distinct ribosome maturation defects in yeast models of Diamond-Blackfan anemia and Shwachman-Diamond syndrome. Haematologica. 2010 Jan; 95(1):57-64. PMID: 19713223.
      View in: PubMed
    54. Suzuki T, Farrar JE, Yegnasubramanian S, Zahed M, Suzuki N, Arceci RJ. Stable knockdown of PASG enhances DNA demethylation but does not accelerate cellular senescence in TIG-7 human fibroblasts. Epigenetics. 2008 Sep; 3(5):281-91. PMID: 18948754.
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    55. Farrar JE, Nater M, Caywood E, McDevitt MA, Kowalski J, Takemoto CM, Talbot CC, Meltzer P, Esposito D, Beggs AH, Schneider HE, Grabowska A, Ball SE, Niewiadomska E, Sieff CA, Vlachos A, Atsidaftos E, Ellis SR, Lipton JM, Gazda HT, Arceci RJ. Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia. Blood. 2008 Sep 01; 112(5):1582-92. PMID: 18535205.
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    56. Farrar J, Nater M, Caywood EH, McDevitt M, Kowalski J, Takemoto CM, Meltzer P, Beggs AH, Schneider HA, Grabowska A, Ball S, Niewiadomska E, Sieff CA, Vlachos A, Atsidaftos E, Lipton JM, Gazda HT, Arceci RA. A Large Subunit Abnormality in Diamond-Blackfan Anemia (DBA) [Abstract]. American Society of Hematology Annual Meeting. 2007; 422.
    57. Zhang L, Anglesio MS, O'Sullivan M, Zhang F, Yang G, Sarao R, Mai PN, Cronin S, Hara H, Melnyk N, Li L, Wada T, Liu PP, Farrar J, Arceci RJ, Sorensen PH, Penninger JM. The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers. Nat Med. 2007 Sep; 13(9):1060-9. PMID: 17694067.
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    58. Neuman DL, Farrar JE, Moresi JM, Vogelsang GB, Higman MA. Toxic absorption of tacrolimus [corrected] in a patient with severe acute graft-versus-host disease. Bone Marrow Transplant. 2005 Nov; 36(10):919-20. PMID: 16151424.
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    59. Farrar JE, Rohrer J, Conley ME. Neutropenia in X-linked agammaglobulinemia. Clin Immunol Immunopathol. 1996 Dec; 81(3):271-6. PMID: 8938104.
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    60. Moore JB, Farrar JE, Arceci RA, Liu J, Ellis SR. Yeast Models for Diamond Blackfan Anemia and Shwachman Diamond Syndrome Differ In Their Effect On Translation of Certain Classes of mRNA [Abstract].
    61. Williams D, Coates T, Shimamura A, Arceci RJ, Bennett C, Bertuch A, Bessler M, Chawla A, Corey SJ, Dror Y, Farrar J, Glader B, Hartung H, Hofmann I, Huang J, Kurre P, Lehmann L, Lipton J, Olson T, Reiss U, Rogers Z, Sieff C, Takemoto C, Vlachos A, Walkovich K, Wang W. Diagnosis and Treatment of Pediatric Acquired Aplastic Anemia (AAA): An Initial Study of the North American Pediatric Aplastic Anemia Consortium (NAPAAC). Pediatr Blood Cancer, 60; S1-105.
    62. Meshinchi S, Ries RE, Farrar JE, Guidry Auvil J, Davidsen TM, Gesuwan P, Trevino LR, Muzny DM, Wheeler DA, Gamis AS, Alonzo TA, Smith MA, Gerhard DS, Arceci RJ. Demonstration of Significant Clonal Evolution from Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing - An NCI/COG TARGET AML Study [Abstract].
    63. Farrar JE, Gazda HT, Beggs AH, Atsidaftos E, Arceci RA, Lipton JM, Vlachos A. Sequence Abnormalities In Genes Encoding Ribosomal Proteins In Patients With Diamond Blackfan Anemia: A Preliminary Report from the Resequencing Project [Abstract].
    64. Meshinchi S, Ries RE, Trevino LR, Hampton OA, Alonzo TA, Farrar JE, Guidry-Auvil J, Davidsen TM, Gesuwan P, Muzny DM, Gamis AS, Helton HL, Wheeler DA, Smith MA, Gerhard DS, Arceci RJ. Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution from Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – An NCI/COG TARGET AML Study. American Society of Hematology Annual Meeting.
    65. Ellis SR, Moore JB, Pavesi E, Dianzani I, Farrar J, Arceci RJ, Vlachos A, Lipton JM, Liu JM. Diamond Blackfan anemia: What’s the 5S ribonucleoprotein subcomplex got to do with it? [Abstract].
    66. Caywood E, Farrar JE, Lipton JM, Arceci RJ. Differential Down-Regulation of RPL35a in Human Bone Marrow Progenitors Demonstrates a p53 Independent Mechanism Mediating the Diamond Blackfan Anemia Phenotype [Abstract]. American Society of Hematology Annual Meeting. 1096.
    67. Mendoza-Naranjo A, Wai DH, Farrar JE, Zhu Q, Mistry P, Lazic N, Ayala FRR, Da Cunha IW, Arceci RJ, Soares FA, Triche TJ, Strauss SJ, Sorensen PJ. ErbB4 is a Novel Driver of Metastasis and Anoikis Resistance in Ewing’s Sarcoma [Abstract].
    68. Fisher R, Henson AL, Quarello P, Aspesi A, Farrar JE, Arceci RJ, Bodine DM, Dianzani I, Lipton JM, Ramenghi U, Vlachos A, Ellis SR. Insights into diagnosis and etiology of Diamond Blackfan anemia by analysis of pre-rRNA processing [Abstract]. American Society of Hematology Annual Meeting.
    69. Farrar JE, Nater M, Caywood EH, McDevitt M, Kowalski J, Takemoto CM, Meltzer P, Beggs AH, Schneider HA, Grabowska A, Ball S, Niewiadomska E, Sieff CA, Vlachos A, Atsidaftos E, Lipton JM, Gazda HT, Arceci RA. A Large Subunit Abnormality in DBA [Abstract].
    70. Osorio DS, Atsidaftos E, Muir E, Seiden H, Gruber D, Farrar JE, Ellis SR, Glader B, Lipton JM, Vlachos A. Prevalence of Elevated Erythrocyte Adenosine Deaminase (eADA) Activity, A Marker of Diamond Blackfan Anemia (DBA), In Patients with Congenital Heart Disease (CHD). Pediatr Blood Cancer, 60; S1-105.
    71. Ochs MF, Farrar JE, Considine M, Ries R, Trevino LR, Alonzo TA, Guidry-Auvil J, Davidsen TM, Gesuwan P, Muzny DM, Gamis AS, Helton HL, Wheeler DA, Smith MA, Gerhard DS, Meshinchi S, Arceci RJ. Genome wide promoter methylation patterns predict AML subtype outcomes and identify novel pathways characterizing diagnostic and relapsed disease in children [Abstract]. American Society of Hematology Annual Meeting.
    72. Vlachos A, Atsidaftos E, Arceci RJ, Ellis SR, Lipton JM, Bodine DM. The Frequent Identification of Ribosomal Protein Gene Deletions in Diamond Blackfan Anemia Patients without Detectable Ribosomal Protein Gene Mutations [Abstract].
    73. Caywood EH, Farrar JE, Lipton JM, Arceci RJ. Differential down-regulation of RPL35a in human bone marrow progenitors demonstrates a p53 independent mechanism mediating the Diamond Blackfan anemia phenotype.
    74. Heuston EF, Farrar JE, Triche T, Buckley J, Wai DH, Ochs M, Considine M, Reaman G, Arceci RJ. 5-Aza-2’-deoxycytidine and Cytarabine Mediate Distinct Effects on Clonogenic Growth, Genome-Wide Methylation and RNA Expression in AML [Abstract].
    75. Helton HL, Ries RE, Alonzo TA, Gerbing RB, Trevino LR, Farrar JE, Guidry-Auvil J, Davidsen TM, Gesuwan P, Muzny DM, Gamis AS, Franklin J, Wheeler DA, Smith MA, Gerhard DS, Arceci RJ, Meshinchi S. Clinically Significant Mutations, Deletions and Translocations involving ETV6 Identified by Whole Genome and Whole Exome Sequencing: a Report from NCI/COG TARGET AML Initiative [Abstract] 54th Annual ASH Meeting, Atlanta, GA. American Society of Hematology Annual Meeting.
    76. Arceci RA, Caywood E, Farrar JE, Nater M, Lipton JM. Down-regulation of Rpl35a and Rps19 in the UT-7/Epo Cell Line Results in Cell Cycle Arrest at G2/M [Abstract].
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