 Transgenes
"Transgenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that are introduced into an organism using GENE TRANSFER TECHNIQUES.
| Descriptor ID |
D019076
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| MeSH Number(s) |
G05.360.340.024.340.825
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| Concept/Terms |
Recombinant Transgenes- Recombinant Transgenes
- Recombinant Transgene
- Transgene, Recombinant
- Transgenes, Recombinant
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Below are MeSH descriptors whose meaning is more general than "Transgenes".
Below are MeSH descriptors whose meaning is more specific than "Transgenes".
This graph shows the total number of publications written about "Transgenes" by people in UAMS Profiles by year, and whether "Transgenes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 2 | 3 | | 2018 | 1 | 1 | 2 | | 2016 | 0 | 2 | 2 | | 2015 | 0 | 4 | 4 | | 2014 | 0 | 3 | 3 | | 2013 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 | | 2010 | 1 | 2 | 3 | | 2008 | 1 | 3 | 4 | | 2007 | 0 | 1 | 1 | | 2006 | 0 | 3 | 3 | | 2004 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2001 | 0 | 3 | 3 | | 1999 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Transgenes" by people in Profiles over the past ten years.
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Patyal P, Kockara NT, Wight PA. The wmN1 Enhancer Region of the Mouse Myelin Proteolipid Protein Gene (mPlp1) is Indispensable for Expression of an mPlp1-lacZ Transgene in Both the CNS and PNS. Neurochem Res. 2020 Mar; 45(3):663-671.
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MacLeod RS, Cawley KM, Gubrij I, Nookaew I, Onal M, O'Brien CA. Effective CRISPR interference of an endogenous gene via a single transgene in mice. Sci Rep. 2019 Nov 21; 9(1):17312.
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Conrad SJ, Liu J. Poxviruses as Gene Therapy Vectors: Generating Poxviral Vectors Expressing Therapeutic Transgenes. Methods Mol Biol. 2019; 1937:189-209.
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Iwata M, Englund DA, Wen Y, Dungan CM, Murach KA, Vechetti IJ, Mobley CB, Peterson CA, McCarthy JJ. A novel tetracycline-responsive transgenic mouse strain for skeletal muscle-specific gene expression. Skelet Muscle. 2018 10 27; 8(1):33.
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Hamdan H, Patyal P, Kockara NT, Wight PA. The wmN1 enhancer region in intron 1 is required for expression of human PLP1. Glia. 2018 08; 66(8):1763-1774.
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White PA, Douglas GR, Phillips DH, Arlt VM. Quantitative relationships between lacZ mutant frequency and DNA adduct frequency in Muta?Mouse tissues and cultured cells exposed to 3-nitrobenzanthrone. Mutagenesis. 2017 03 01; 32(2):299-312.
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Coleman CM, Sisk JM, Halasz G, Zhong J, Beck SE, Matthews KL, Venkataraman T, Rajagopalan S, Kyratsous CA, Frieman MB. CD8+ T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory Syndrome. J Virol. 2017 Jan 01; 91(1).
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Hegde M, Mukherjee M, Grada Z, Pignata A, Landi D, Navai SA, Wakefield A, Fousek K, Bielamowicz K, Chow KK, Brawley VS, Byrd TT, Krebs S, Gottschalk S, Wels WS, Baker ML, Dotti G, Mamonkin M, Brenner MK, Orange JS, Ahmed N. Tandem CAR T cells targeting HER2 and IL13Ra2 mitigate tumor antigen escape. J Clin Invest. 2016 08 01; 126(8):3036-52.
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P?pin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK. AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):E4418-27.
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Cao M, Theus SA, Straub KD, Figueroa JA, Mirandola L, Chiriva-Internati M, Hermonat PL. AAV2/8-humanFOXP3 gene therapy shows robust anti-atherosclerosis efficacy in LDLR-KO mice on high cholesterol diet. J Transl Med. 2015 Jul 18; 13:235.
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Onal M, Bishop KA, St John HC, Danielson AL, Riley EM, Piemontese M, Xiong J, Goellner JJ, O'Brien CA, Pike JW. A DNA segment spanning the mouse Tnfsf11 transcription unit and its upstream regulatory domain rescues the pleiotropic biologic phenotype of the RANKL null mouse. J Bone Miner Res. 2015 May; 30(5):855-68.
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