 Peptide Chain Initiation, Translational
"Peptide Chain Initiation, Translational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A process of GENETIC TRANSLATION whereby the formation of a peptide chain is started. It includes assembly of the RIBOSOME components, the MESSENGER RNA coding for the polypeptide to be made, INITIATOR TRNA, and PEPTIDE INITIATION FACTORS; and placement of the first amino acid in the peptide chain. The details and components of this process are unique for prokaryotic protein biosynthesis and eukaryotic protein biosynthesis.
| Descriptor ID |
D010442
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| MeSH Number(s) |
G02.111.087.675.871.650 G02.149.115.675.871.650 G03.495.770.871.650
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| Concept/Terms |
Peptide Chain Initiation, Translational- Peptide Chain Initiation, Translational
- Protein Biosynthesis Initiation
- Biosynthesis Initiation, Protein
- Initiation, Protein Biosynthesis
- Protein Chain Initiation, Translational
- Translation Initiation, Genetic
- Genetic Translation Initiation
- Initiation, Genetic Translation
- Translational Initiation, Protein
- Initiation, Protein Translational
- Protein Translational Initiation
- Translational Peptide Chain Initiation
- Protein Translation Initiation
- Chain Initiation, Peptide, Translational
- Translation Initiation, Protein
- Initiation, Protein Translation
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Below are MeSH descriptors whose meaning is more general than "Peptide Chain Initiation, Translational".
Below are MeSH descriptors whose meaning is more specific than "Peptide Chain Initiation, Translational".
This graph shows the total number of publications written about "Peptide Chain Initiation, Translational" by people in UAMS Profiles by year, and whether "Peptide Chain Initiation, Translational" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2011 | 4 | 0 | 4 | | 2010 | 1 | 0 | 1 | | 2009 | 2 | 0 | 2 | | 2008 | 1 | 0 | 1 | | 2007 | 0 | 3 | 3 |
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Below are the most recent publications written about "Peptide Chain Initiation, Translational" by people in Profiles over the past ten years.
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Jackson RJ. The current status of vertebrate cellular mRNA IRESs. Cold Spring Harb Perspect Biol. 2013 Feb 01; 5(2).
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Arumugam K, Macnicol MC, Macnicol AM. Autoregulation of Musashi1 mRNA translation during Xenopus oocyte maturation. Mol Reprod Dev. 2012 Aug; 79(8):553-63.
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Yu Y, Sweeney TR, Kafasla P, Jackson RJ, Pestova TV, Hellen CU. The mechanism of translation initiation on Aichivirus RNA mediated by a novel type of picornavirus IRES. EMBO J. 2011 Aug 26; 30(21):4423-36.
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Pöyry TA, Jackson RJ. Mechanisms governing the selection of translation initiation sites on foot-and-mouth disease virus RNA. J Virol. 2011 Oct; 85(19):10178-88.
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Ricci EP, Limousin T, Soto-Rifo R, Allison R, Pöyry T, Decimo D, Jackson RJ, Ohlmann T. Activation of a microRNA response in trans reveals a new role for poly(A) in translational repression. Nucleic Acids Res. 2011 Jul; 39(12):5215-31.
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