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Search Results to Christopher Wardell

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Wardell, Christopher

One or more keywords matched the following items that are connected to Wardell, Christopher

Item Type	Name
Academic Article	A molecular diagnostic approach able to detect the recurrent genetic prognostic factors typical of presenting myeloma.
Academic Article	Improved risk stratification in myeloma using a microRNA-based classifier.
Academic Article	Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations.
Academic Article	Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival.
Academic Article	Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma.
Academic Article	Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.
Academic Article	The clinical impact and molecular biology of del(17p) in multiple myeloma treated with conventional or thalidomide-based therapy.
Academic Article	Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma.
Academic Article	Gender disparities in the tumor genetics and clinical outcome of multiple myeloma.
Academic Article	Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells.
Academic Article	A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.
Academic Article	Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms.
Academic Article	APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma.
Academic Article	High expression levels of the mammalian target of rapamycin inhibitor DEPTOR are predictive of response to thalidomide in myeloma.
Academic Article	Identification of a novel t(7;14) translocation in multiple myeloma resulting in overexpression of EGFR.
Academic Article	Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.
Academic Article	A modified method for whole exome resequencing from minimal amounts of starting DNA.
Academic Article	The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma.
Academic Article	Genomewide profiling of copy-number alteration in monoclonal gammopathy of undetermined significance.
Academic Article	Search for rare protein altering variants influencing susceptibility to multiple myeloma.
Academic Article	The spectrum of somatic mutations in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape than that in multiple myeloma.
Academic Article	Neutral tumor evolution in myeloma is associated with poor prognosis.
Academic Article	A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis.
Academic Article	Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.
Academic Article	The genomic landscape of plasma cells in systemic light chain amyloidosis.
Academic Article	Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients.
Academic Article	Poor overall survival in hyperhaploid multiple myeloma is defined by double-hit bi-allelic inactivation of TP53.
Academic Article	Daratumumab and dexamethasone is safe and effective for triple refractory myeloma patients: final results of the IFM 2014-04 (Etoile du Nord) trial.
Academic Article	Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma.
Academic Article	An acquired high-risk chromosome instability phenotype in multiple myeloma: Jumping 1q Syndrome.
Academic Article	BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma.
Academic Article	Differential RNA splicing as a potentially important driver mechanism in multiple myeloma.
Academic Article	TarPan: an easily adaptable targeted sequencing panel viewer for research and clinical use.
Academic Article	Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns.
Academic Article	The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma.
Academic Article	High-risk transcriptional profiles in multiple myeloma are an acquired feature that can occur in any subtype and more frequently with each subsequent relapse.
Academic Article	Plasma cells expression from smouldering myeloma to myeloma reveals the importance of the PRC2 complex, cell cycle progression, and the divergent evolutionary pathways within the different molecular subgroups.
Academic Article	Structural variants shape the genomic landscape and clinical outcome of multiple myeloma.

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