Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations.
Pawlyn C, Melchor L, Murison A, Wardell CP, Brioli A, Boyle EM, Kaiser MF, Walker BA, Begum DB, Dahir NB, Proszek P, Gregory WM, Drayson MT, Jackson GH, Ross FM, Davies FE, Morgan GJ. Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations. Blood. 2015 Jan 29; 125(5):831-40.
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Aged
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Antineoplastic Combined Chemotherapy Protocols
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Chromosomes, Human, Pair 11
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Chromosomes, Human, Pair 14
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Chromosomes, Human, Pair 16
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Chromosomes, Human, Pair 20
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Chromosomes, Human, Pair 4
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Cytogenetic Analysis
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Diploidy
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Female
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Gene Expression Regulation, Neoplastic
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Humans
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Immunoglobulin Heavy Chains
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In Situ Hybridization, Fluorescence
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Male
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Middle Aged
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Multiple Myeloma
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Prognosis
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Signal Transduction
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Single-Cell Analysis
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Survival Analysis
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Translocation, Genetic