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Search Results to Peter Crooks

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Crooks, Peter

One or more keywords matched the following items that are connected to Crooks, Peter

Item Type	Name
Concept	Lobeline
Academic Article	meso-Transdiene analogs inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release.
Academic Article	Lobelane decreases methamphetamine self-administration in rats.
Academic Article	Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters.
Academic Article	The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse.
Academic Article	Synthesis and evaluation of novel azetidine analogs as potent inhibitors of vesicular [3H]dopamine uptake.
Academic Article	Synthesis and evaluation of a series of homologues of lobelane at the vesicular monoamine transporter-2.
Academic Article	Indirect trapping of the retroconjugate addition reaction intermediate involved in the epimerization of lobeline: application to the synthesis of (-)-sedamine.
Academic Article	Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters.
Academic Article	Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters.
Academic Article	Quinlobelane: a water-soluble lobelane analogue and inhibitor of VMAT2.
Academic Article	Phenyl ring-substituted lobelane analogs: inhibition of [?H]dopamine uptake at the vesicular monoamine transporter-2.
Academic Article	Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter.
Academic Article	Design, synthesis and interaction at the vesicular monoamine transporter-2 of lobeline analogs: potential pharmacotherapies for the treatment of psychostimulant abuse.
Academic Article	Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2.
Academic Article	Lobelane analogues as novel ligands for the vesicular monoamine transporter-2.
Academic Article	The effect of VMAT2 inhibitor GZ-793A on the reinstatement of methamphetamine-seeking in rats.
Academic Article	Stereocontrolled synthesis and pharmacological evaluation of cis-2,6-diphenethyl-1-azabicyclo[2.2.2]octanes as lobelane analogues.
Academic Article	Oral administration of GZ-793A, a VMAT2 inhibitor, decreases methamphetamine self-administration in rats.
Academic Article	The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats.
Academic Article	GZ-793A, a lobelane analog, interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamine.
Academic Article	Pyrrolidine analogs of GZ-793A: synthesis and evaluation as inhibitors of the vesicular monoamine transporter-2 (VMAT2).
Academic Article	Computational neural network analysis of the affinity of lobeline and tetrabenazine analogs for the vesicular monoamine transporter-2.
Academic Article	The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
Academic Article	Effects of VMAT2 inhibitors lobeline and GZ-793A on methamphetamine-induced changes in dopamine release, metabolism and synthesis in vivo.
Academic Article	Pyrrolidine analogues of lobelane: relationship of affinity for the dihydrotetrabenazine binding site with function of the vesicular monoamine transporter 2 (VMAT2).
Academic Article	Quinolyl analogues of norlobelane: novel potent inhibitors of [(3)H]dihydrotetrabenazine binding and [(3)H]dopamine uptake at the vesicular monoamine transporter-2.
Academic Article	Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release.
Academic Article	1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2.
Academic Article	Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2.
Academic Article	Synthesis of Lobeline, Lobelane and their Analogues. A Review.
Academic Article	GZ-793A inhibits the neurochemical effects of methamphetamine via a selective interaction with the vesicular monoamine transporter-2.
Academic Article	Varenicline and GZ-793A differentially decrease methamphetamine self-administration under a multiple schedule of reinforcement in rats.
Academic Article	New Scaffold for Lead Compounds to Treat Methamphetamine Use Disorders.

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Lobeline