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Search Results to Frits Van Rhee

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Van Rhee, Frits

One or more keywords matched the following items that are connected to Van Rhee, Frits

Item Type	Name
Academic Article	DTPACE: an effective, novel combination chemotherapy with thalidomide for previously treated patients with myeloma.
Academic Article	Prognostic factors in allogeneic transplantation for patients with high-risk multiple myeloma after reduced intensity conditioning.
Academic Article	Treatment advances in multiple myeloma.
Academic Article	Immunization with a recombinant MAGE-A3 protein after high-dose therapy for myeloma.
Academic Article	High serum-free light chain levels and their rapid reduction in response to therapy define an aggressive multiple myeloma subtype with poor prognosis.
Academic Article	Protein transduction of dendritic cells for NY-ESO-1-based immunotherapy of myeloma.
Academic Article	Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma.
Academic Article	TP53 deletion is not an adverse feature in multiple myeloma treated with total therapy 3.
Academic Article	Magnetic resonance imaging in multiple myeloma: diagnostic and clinical implications.
Academic Article	NY-ESO-1 immunotherapy for multiple myeloma.
Academic Article	Human placenta-derived adherent cells prevent bone loss, stimulate bone formation, and suppress growth of multiple myeloma in bone.
Academic Article	Completion of premaintenance phases in total therapies 2 and 3 improves clinical outcomes in multiple myeloma: an important variable to be considered in clinical trial designs.
Academic Article	Role of Bruton's tyrosine kinase in myeloma cell migration and induction of bone disease.
Academic Article	The molecular classification of multiple myeloma.
Academic Article	Prognostic implications of serial 18-fluoro-deoxyglucose emission tomography in multiple myeloma treated with total therapy 3.
Academic Article	Highly activated and expanded natural killer cells for multiple myeloma immunotherapy.
Academic Article	Risk factors for MDS and acute leukemia following total therapy 2 and 3 for multiple myeloma.
Academic Article	High-risk myeloma is associated with global elevation of miRNAs and overexpression of EIF2C2/AGO2.
Academic Article	Gene expression profiling of plasma cells at myeloma relapse from tandem transplantation trial Total Therapy 2 predicts subsequent survival.
Academic Article	CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma.
Academic Article	Optimizing dendritic cell-based immunotherapy in multiple myeloma: intranodal injections of idiotype-pulsed CD40 ligand-matured vaccines led to induction of type-1 and cytotoxic T-cell immune responses in patients.
Academic Article	Metronomic therapy is an effective salvage treatment for heavily pre-treated relapsed/refractory multiple myeloma.
Academic Article	Thalidomide in total therapy 2 overcomes inferior prognosis of myeloma with low expression of the glucocorticoid receptor gene NR3C1.
Academic Article	Second malignancies in total therapy 2 and 3 for newly diagnosed multiple myeloma: influence of thalidomide and lenalidomide during maintenance.
Academic Article	NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses.
Academic Article	Reiterative survival analyses of total therapy 2 for multiple myeloma elucidate follow-up time dependency of prognostic variables and treatment arms.
Academic Article	Complete response in myeloma extends survival without, but not with history of prior monoclonal gammopathy of undetermined significance or smouldering disease.
Academic Article	A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease.
Academic Article	Benefit of complete response in multiple myeloma limited to high-risk subgroup identified by gene expression profiling.
Academic Article	Pharmacogenomics of bortezomib test-dosing identifies hyperexpression of proteasome genes, especially PSMD4, as novel high-risk feature in myeloma treated with Total Therapy 3.
Academic Article	Total Therapy 3 for multiple myeloma: prognostic implications of cumulative dosing and premature discontinuation of VTD maintenance components, bortezomib, thalidomide, and dexamethasone, relevant to all phases of therapy.
Academic Article	NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity.
Academic Article	Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells.
Academic Article	International staging system and metaphase cytogenetic abnormalities in the era of gene expression profiling data in multiple myeloma treated with total therapy 2 and 3 protocols.
Academic Article	Extramedullary disease portends poor prognosis in multiple myeloma and is over-represented in high-risk disease even in the era of novel agents.
Academic Article	High-dose melphalan-based autotransplants for multiple myeloma: the Arkansas experience since 1989 in 3077 patients.
Academic Article	F18-fluorodeoxyglucose positron emission tomography in the context of other imaging techniques and prognostic factors in multiple myeloma.
Academic Article	Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma.
Academic Article	Epigenetic modulation of MAGE-A3 antigen expression in multiple myeloma following treatment with the demethylation agent 5-azacitidine and the histone deacetlyase inhibitor MGCD0103.
Concept	Antibodies, Neoplasm
Concept	Antigens, Neoplasm
Concept	Bone Neoplasms
Concept	Neoplasm Metastasis
Concept	Liver Neoplasms
Concept	Central Nervous System Neoplasms
Concept	Neoplasm Staging
Concept	Neoplasm Invasiveness
Concept	Neoplasms, Glandular and Epithelial
Concept	Genes, Tumor Suppressor
Concept	Neoplasms, Plasma Cell
Concept	Tumor Microenvironment
Concept	Cancer Vaccines
Concept	Hematologic Neoplasms
Concept	Neoplasms, Second Primary
Concept	Tumor Burden
Concept	Tumor Suppressor Protein p53
Concept	Lymphocytes, Tumor-Infiltrating
Concept	DNA, Neoplasm
Concept	Neoplasm Recurrence, Local
Concept	Soft Tissue Neoplasms
Concept	Cell Line, Tumor
Concept	Skin Neoplasms
Concept	Thyroid Neoplasms
Concept	Ovarian Neoplasms
Concept	Tumor Cells, Cultured
Concept	RNA, Neoplasm
Concept	Drug Resistance, Neoplasm
Concept	Neoplasm Proteins
Concept	Genes, Neoplasm
Concept	Neoplasm, Residual
Concept	Neoplasms
Academic Article	Efficient lysis of epithelial ovarian cancer cells by MAGE-A3-induced cytotoxic T lymphocytes using rAAV-6 capsid mutant vector.
Academic Article	High-dose melphalan-based autotransplants for muliple myeloma: the Arkansas experience since 1989 in 3077 patients
Academic Article	Cancer and Gene Therapy
Academic Article	In multiple myeloma, 14q32 translocations are nonrandom chromosomal fusions driving high expression levels of the respective partner genes.
Academic Article	Patterns of central nervous system involvement in relapsed and refractory multiple myeloma.
Academic Article	Clinical grade purification and expansion of natural killer cells.
Academic Article	Ex vivo-expanded natural killer cells demonstrate robust proliferation in vivo in high-risk relapsed multiple myeloma patients.
Academic Article	The future of autologous stem cell transplantation in myeloma.
Academic Article	CYR61/CCN1 overexpression in the myeloma microenvironment is associated with superior survival and reduced bone disease.
Academic Article	Curing myeloma at last: defining criteria and providing the evidence.
Academic Article	Haematological cancer: Optimizing the treatment of multiple myeloma.
Academic Article	Analysis of Inflammatory and Anemia-Related Biomarkers in a Randomized, Double-Blind, Placebo-Controlled Study of Siltuximab (Anti-IL6 Monoclonal Antibody) in Patients With Multicentric Castleman Disease.
Academic Article	Four genes predict high risk of progression from smoldering to symptomatic multiple myeloma (SWOG S0120).
Academic Article	Atrial Fibrillation in Hematologic Malignancies, Especially After Autologous Hematopoietic Stem Cell Transplantation: Review of Risk Factors, Current Management, and Future Directions.
Academic Article	Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma.
Academic Article	Assessment of Total Lesion Glycolysis by 18F FDG PET/CT Significantly Improves Prognostic Value of GEP and ISS in Myeloma.
Academic Article	Profile of elotuzumab and its potential in the treatment of multiple myeloma.
Academic Article	MAF protein mediates innate resistance to proteasome inhibition therapy in multiple myeloma.
Academic Article	Transplantation for Multiple Myeloma.
Academic Article	Adverse Metaphase Cytogenetics Can Be Overcome by Adding Bortezomib and Thalidomide to Fractionated Melphalan Transplants.
Academic Article	The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: multiple myeloma, lymphoma, and acute leukemia.
Academic Article	The prognostic value of the depth of response in multiple myeloma depends on the time of assessment, risk status and molecular subtype.
Academic Article	The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma.
Academic Article	Low expression of hexokinase-2 is associated with false-negative FDG-positron emission tomography in multiple myeloma.
Academic Article	Immunologic approaches for the treatment of multiple myeloma.
Academic Article	The Pattern of Mesenchymal Stem Cell Expression Is an Independent Marker of Outcome in Multiple Myeloma.
Academic Article	Treatment to suppression of focal lesions on positron emission tomography-computed tomography is a therapeutic goal in newly diagnosed multiple myeloma.
Academic Article	Kinase domain activation through gene rearrangement in multiple myeloma.
Academic Article	MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma.
Academic Article	Mesenchymal stem cells gene signature in high-risk myeloma bone marrow linked to suppression of distinct IGFBP2-expressing small adipocytes.
Grant	Potentiating Natural Killer Cell Anti-Myeloma Effects
Grant	Tumor Antigen-Pulsed Autologous Dendritic Cell Vaccination Administered Intranodally in Multiple Myeloma Patients
Academic Article	Storming the Castle with TCP.
Academic Article	Lack of Spleen Signal on Diffusion Weighted MRI is associated with High Tumor Burden and Poor Prognosis in Multiple Myeloma: A Link to Extramedullary Hematopoiesis?
Academic Article	An acquired high-risk chromosome instability phenotype in multiple myeloma: Jumping 1q Syndrome.
Academic Article	Long-term outcomes after autologous stem cell transplantation for multiple myeloma.
Academic Article	BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma.
Academic Article	Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns.
Academic Article	Accelerated single cell seeding in relapsed multiple myeloma.
Academic Article	The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma.
Academic Article	Race-Dependent Differences in Risk, Genomics, and Epstein-Barr Virus Exposure in Monoclonal Gammopathies: Results of SWOG S0120.
Academic Article	Monitoring treatment response and disease progression in myeloma with circulating cell-free DNA.
Academic Article	Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials.
Academic Article	The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma.
Academic Article	Ixazomib-lenalidomide-dexamethasone in routine clinical practice: effectiveness in relapsed/refractory multiple myeloma.
Academic Article	Persistent bone marrow minimal residual disease as a "high-risk" disease feature in multiple myeloma.
Academic Article	TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies.
Academic Article	High-risk transcriptional profiles in multiple myeloma are an acquired feature that can occur in any subtype and more frequently with each subsequent relapse.
Academic Article	Plasma cells expression from smouldering myeloma to myeloma reveals the importance of the PRC2 complex, cell cycle progression, and the divergent evolutionary pathways within the different molecular subgroups.
Academic Article	Salvage Autologous Stem Cell Transplantation in Daratumumab-Refractory Multiple Myeloma.
Academic Article	Epigenetic Deregulation of Telomere-Related Genes in Newly Diagnosed Multiple Myeloma Patients.
Academic Article	Clinical implications of loss of bone marrow minimal residual disease negativity in multiple myeloma.
Academic Article	Predicting risk of progression in relapsed multiple myeloma using traditional risk models, focal lesion assessment with PET-CT and minimal residual disease status.
Academic Article	Functional dissection of inherited non-coding variation influencing multiple myeloma risk.
Academic Article	Tandem autologous stem cell transplantation in patients with persistent bone marrow minimal residual disease after first transplantation in multiple myeloma.
Academic Article	Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma.
Academic Article	Enrollment of Black Participants in Pivotal Clinical Trials Supporting US Food and Drug Administration Approval of Chimeric Antigen Receptor-T Cell Therapy for Hematological Malignant Neoplasms.
Academic Article	Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level.
Academic Article	The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states.
Academic Article	Concomitant deletion of the short arm (del(1p13.3)) and amplification or gain (1q21) of chromosome 1 by fluorescence in situ hybridization are associated with a poor clinical outcome in multiple myeloma.
Academic Article	Risk of infections associated with the use of bispecific antibodies in multiple myeloma: a pooled analysis.
Academic Article	Overall Survival Analysis of the Use of Elotuzumab in ELOQUENT-3 Trial.
Grant	Tumor Antigen-Pulsed Autologous Dendritic Cell Vaccination Administered Intranodally in Multiple Myeloma Patients
Academic Article	Growth and dormancy control of myeloma cells by mesenchymal stem cells.
Academic Article	Under-representation of black patients with multiple myeloma in studies supporting International Myeloma Working Group guidelines.
Academic Article	Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level.
Academic Article	EDNRA-Expressing Mesenchymal Cells Are Expanded in Myeloma Interstitial Bone Marrow and Associated with Disease Progression.
Academic Article	The changing spectrum of infection with BCMA and GPRC5D targeting bispecific antibody (bsAb) therapy in patients with relapsed refractory multiple myeloma.
Academic Article	High NEK2 expression in myeloid progenitors suppresses T?cell immunity in multiple myeloma.
Academic Article	Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth.
Academic Article	Development and validation of an individualized and weighted Myeloma Prognostic Score System (MPSS) in patients with newly diagnosed multiple myeloma.
Academic Article	Prognostic value of ferritin in ASCT MM patients: integration with GEP models and ISS series systems.
Academic Article	Teclistamab in relapsed refractory multiple myeloma: multi-institutional real-world study.
Academic Article	A Risk Stratification System in Myeloma Patients with Autologous Stem Cell Transplantation.

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Neoplasms