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Search Results to Fang Zheng

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Zheng, Fang

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I have a long-standing interest in the pathophysiology of epilepsy and stroke. Initially trained as a channel biophysicist, I have also acquired experience and knowledge in molecular biology, biochemistry and pharmacology over the years. This allows me to adopt a multidisciplinary approach in my research. I have a equally long-standing interest in the functional roles of metabotropic glutamate receptor (mGluR), and this interest has led to my recent focus on transient receptor potential (TRPC) channels for the last 6 years. We have demonstrated the unique roles of various TRPC family members in seizure and excitotoxicity.

One or more keywords matched the following items that are connected to Zheng, Fang

Item Type	Name
Academic Article	Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration.
Academic Article	Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms.
Concept	Seizures
Academic Article	The role of canonical transient receptor potential channels in seizure and excitotoxicity.
Academic Article	The role of TRPC1 in mGluR agonist-induced epileptic burst firing and seizure-induced neuronal cell death in the mouse lateral septum
Academic Article	A Novel Selective Muscarinic Acetylcholine Receptor Subtype 1 (M1 mAChR) Antagonist Reduces Seizures Without Impairing Hippocampal-Dependent Learning
Academic Article	Critical role of canonical transient receptor potential channel 7 in initiation of seizures.
Academic Article	Pilocarpine-induced status epilepticus in mice: A comparison of spectral analysis of electroencephalogram and behavioral grading using the Racine scale.
Grant	METABOTROPIC GLUTAMATE RECEPTORS AND EXCITOTOXICITY
Grant	Canonical Transient Receptor Potential Channels and Excitotoxicity
Grant	ZINC-DEPENDENT APPARENT DESENSITIZATION OF NMDA RECEPTOR
Grant	The Role of Endothelial TRPC3 Channels in Neurovascular Coupling
Academic Article	Convulsant doses of abused synthetic cannabinoid receptor agonists AB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA and JWH-018 do not elicit electroencephalographic (EEG) seizures in male mice.

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Seizures