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Search Results to Fang Zheng

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One or more keywords matched the following properties of Zheng, Fang

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research overview I have a long-standing interest in the pathophysiology of epilepsy and stroke. Initially trained as a channel biophysicist, I have also acquired experience and knowledge in molecular biology, biochemistry and pharmacology over the years. This allows me to adopt a multidisciplinary approach in my research. I have a equally long-standing interest in the functional roles of metabotropic glutamate receptor (mGluR), and this interest has led to my recent focus on transient receptor potential (TRPC) channels for the last 6 years. We have demonstrated the unique roles of various TRPC family members in seizure and excitotoxicity.

One or more keywords matched the following items that are connected to Zheng, Fang

Item TypeName
Academic Article Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration.
Academic Article The role of canonical transient receptor potential channels in seizure and excitotoxicity.
Academic Article The role of the NR1 subunit in zinc-dependent desensitization of NR1/NR2A receptors
Academic Article The role of TRPC1 in mGluR agonist-induced epileptic burst firing and seizure-induced neuronal cell death in the mouse lateral septum
Academic Article Exploring the role of the high affinity zinc site of the NMDA receptor using an NR2AH128A knockin mouse model
Academic Article The role of TRPC3 in excitotoxicity in the mouse hippocampus
Academic Article Critical role of canonical transient receptor potential channel 7 in initiation of seizures.
Academic Article TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice.
Grant METABOTROPIC GLUTAMATE RECEPTORS AND EXCITOTOXICITY
Grant Canonical Transient Receptor Potential Channels and Excitotoxicity
Grant MODULATION OF NMDA RECEPTORS BY TYROSINE KINASES
Grant ZINC-DEPENDENT APPARENT DESENSITIZATION OF NMDA RECEPTOR
Grant The Role of Endothelial TRPC3 Channels in Neurovascular Coupling
Grant The role of TRPC3 channels in periinfarct depression and stroke
Grant The role of TRPC3 channels in neurovascular coupling and peri-infarct depression
Grant The role of TRPC3 channels in periinfarct depression and stroke
Grant The role of TRPC3 channels in neurovascular coupling and peri-infarct depression
Grant The role of the endothelial NPYR1-TRPC3-ET1 signaling axis in neurovascular coupling dysfunction
Grant The role of the endothelial NPYR1-TRPC3-ET1 signaling axis in neurovascular coupling dysfunction

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