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Search Results to John Imig

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One or more keywords matched the following items that are connected to Imig, John

Item TypeName
Concept Male
Academic Article Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats.
Academic Article Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome.
Academic Article Calcium and chloride channel activation by angiotensin II-AT1 receptors in preglomerular vascular smooth muscle cells.
Academic Article Synergistic actions of enalapril and tempol during chronic angiotensin II-induced hypertension.
Academic Article Protein phosphatase 2A and Ca2+-activated K+ channels contribute to 11,12-epoxyeicosatrienoic acid analog mediated mesenteric arterial relaxation.
Academic Article ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin.
Academic Article Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes.
Academic Article Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats.
Academic Article Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats.
Academic Article Role of the cytochrome P-450/ epoxyeicosatrienoic acids pathway in the pathogenesis of renal dysfunction in cirrhosis.
Academic Article Azilsartan improves glycemic status and reduces kidney damage in zucker diabetic fatty rats.
Academic Article Cytochrome P450 epoxygenases provide a novel mechanism for penile erection.
Academic Article Tumor necrosis factor alpha blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension.
Academic Article Effects of chronic cytochrome P-450 inhibition on the course of hypertension and end-organ damage in Ren-2 transgenic rats.
Academic Article Tim-1 Deficiency Aggravates High-Fat Diet-Induced Steatohepatitis in Mice.
Academic Article Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting.
Academic Article Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension.
Academic Article Replacement of Lost Substance P Reduces Fibrosis in the Diabetic Heart by Preventing Adverse Fibroblast and Macrophage Phenotype Changes.
Academic Article The roles of intrarenal 20-hydroxyeicosatetraenoic and epoxyeicosatrienoic acids in the regulation of renal function in hypertensive Ren-2 transgenic rats.
Academic Article Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels.
Academic Article Renal AT1 receptor protein expression during the early stage of diabetes mellitus.
Academic Article Elevated Aminopeptidase P Attenuates Cerebral Arterial Responses to Bradykinin in Fawn-Hooded Hypertensive Rats.
Academic Article 11,12,20-Trihydroxy-eicosa-8(Z)-enoic acid: a selective inhibitor of 11,12-EET-induced relaxations of bovine coronary and rat mesenteric arteries.
Academic Article Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.
Academic Article TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive rats.
Academic Article Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib.
Academic Article Contribution of prostaglandin EP(2) receptors to renal microvascular reactivity in mice.
Academic Article Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation.
Academic Article Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system.
Academic Article Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats.
Academic Article 20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Academic Article Infarct size-limiting effect of epoxyeicosatrienoic acid analog EET-B is mediated by hypoxia-inducible factor-1a via downregulation of prolyl hydroxylase 3.
Academic Article A dual farnesoid X receptor/soluble epoxide hydrolase modulator treats non-alcoholic steatohepatitis in mice.
Academic Article Radiation-induced afferent arteriolar endothelial-dependent dysfunction involves decreased epoxygenase metabolites.
Academic Article Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids.
Academic Article Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis.
Academic Article Decreased renal cytochrome P450 2C enzymes and impaired vasodilation are associated with angiotensin salt-sensitive hypertension.
Academic Article Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension.
Academic Article p66Shc regulates renal vascular tone in hypertension-induced nephropathy.
Academic Article Increased blood pressure in mice lacking cytochrome P450 2J5.
Academic Article Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Academic Article A dual COX-2/sEH inhibitor improves the metabolic profile and reduces kidney injury in Zucker diabetic fatty rat.
Academic Article Regulation of Cardiac Mast Cell Maturation and Function by the Neurokinin-1 Receptor in the Fibrotic Heart.
Academic Article Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension.
Academic Article Soluble epoxide hydrolase inhibition and peroxisome proliferator activated receptor ? agonist improve vascular function and decrease renal injury in hypertensive obese rats.
Academic Article Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet.
Academic Article Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2+-activated K+ Channels.
Academic Article Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection.
Academic Article Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats.
Academic Article Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension.
Academic Article Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.
Academic Article Anti-inflammatory effects of ?-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension.
Academic Article Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice.
Academic Article Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats.
Academic Article Downregulation of renal CYP-derived eicosanoid synthesis in rats with diet-induced hypertension.
Academic Article 12-Hydroxyeicosatetraenoic acid participates in angiotensin II afferent arteriolar vasoconstriction by activating L-type calcium channels.
Academic Article Simvastatin and tempol protect against endothelial dysfunction and renal injury in a model of obesity and hypertension.
Academic Article Intrarenal cytochrome P-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip Goldblatt hypertensive rats.
Academic Article Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats.
Academic Article Cytochrome P450 epoxygenase-derived epoxyeicosatrienoic acids contribute to insulin sensitivity in mice and in humans.
Academic Article The epoxyeicosatrienoic acid analog PVPA ameliorates cyclosporine-induced hypertension and renal injury in rats.
Academic Article Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet.
Academic Article Combined treatment with epoxyeicosatrienoic acid analog and 20-hydroxyeicosatetraenoic acid antagonist provides substantial hypotensive effect in spontaneously hypertensive rats.
Academic Article Salt-sensitive hypertension after exposure to angiotensin is associated with inability to upregulate renal epoxygenases.
Academic Article Obesity induced renal oxidative stress contributes to renal injury in salt-sensitive hypertension.
Academic Article Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage.
Academic Article Mechanisms involved in oleamide-induced vasorelaxation in rat mesenteric resistance arteries.
Academic Article Epoxyeicosatrienoic acid analogue mitigates kidney injury in a rat model of radiation nephropathy.
Academic Article Elevated arterial pressure impairs autoregulation independently of AT(1) receptor activation.
Academic Article Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.
Academic Article Dual soluble epoxide hydrolase inhibitor/PPAR-? agonist attenuates renal fibrosis.
Academic Article P2X receptor-stimulated calcium responses in preglomerular vascular smooth muscle cells involves 20-hydroxyeicosatetraenoic acid.
Academic Article Ang II accumulation in rat renal endosomes during Ang II-induced hypertension: role of AT(1) receptor.
Academic Article Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.
Academic Article Kidney-Targeted Epoxyeicosatrienoic Acid Analog, EET-F01, Reduces Inflammation, Oxidative Stress, and Cisplatin-Induced Nephrotoxicity.
Academic Article Azilsartan decreases renal and cardiovascular injury in the spontaneously hypertensive obese rat.
Academic Article Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Academic Article Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension.
Academic Article Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.
Academic Article Peroxisome proliferator-activated receptor-alpha activation reduces salt-dependent hypertension during chronic endothelin B receptor blockade.
Academic Article Impaired Ca2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension.
Academic Article Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior.
Academic Article Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats.
Academic Article An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension.
Academic Article Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy.
Academic Article An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats.
Academic Article Age-related alterations in NOS and oxidative stress in mesenteric arteries from male and female rats.
Academic Article PPAR-alpha activator fenofibrate increases renal CYP-derived eicosanoid synthesis and improves endothelial dilator function in obese Zucker rats.
Academic Article Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity.
Academic Article Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria.
Academic Article Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats.
Academic Article L-type calcium channels in the renal microcirculatory response to endothelin.
Academic Article Glomerular expression of kidney injury molecule-1 and podocytopenia in diabetic glomerulopathy.
Academic Article Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes.
Academic Article A novel dual PPAR-? agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes.
Academic Article Dual soluble epoxide hydrolase inhibitor - farnesoid X receptor agonist interventional treatment attenuates renal inflammation and fibrosis.
Academic Article Kidney Injury by Unilateral Ureteral Obstruction in Mice Lacks Sex Differences.

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