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Search Results to John Imig

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One or more keywords matched the following items that are connected to Imig, John

Item TypeName
Concept Hypertension, Renovascular
Concept Hypertension, Renal
Concept Hypertension, Malignant
Concept Hypertension
Academic Article Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats.
Academic Article Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome.
Academic Article Synergistic actions of enalapril and tempol during chronic angiotensin II-induced hypertension.
Academic Article Inhibition of soluble epoxide hydrolase improves the impaired pressure-natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats.
Academic Article Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats.
Academic Article Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats.
Academic Article Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats.
Academic Article Tumor necrosis factor alpha blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension.
Academic Article Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation.
Academic Article Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease.
Academic Article Effects of chronic cytochrome P-450 inhibition on the course of hypertension and end-organ damage in Ren-2 transgenic rats.
Academic Article Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats.
Academic Article Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting.
Academic Article Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension.
Academic Article Eicosanoids and renal vascular function in diseases.
Academic Article The roles of intrarenal 20-hydroxyeicosatetraenoic and epoxyeicosatrienoic acids in the regulation of renal function in hypertensive Ren-2 transgenic rats.
Academic Article Elevated Aminopeptidase P Attenuates Cerebral Arterial Responses to Bradykinin in Fawn-Hooded Hypertensive Rats.
Academic Article Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.
Academic Article TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive rats.
Academic Article Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib.
Academic Article Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system.
Academic Article Epoxyeicosatrienoic acid analog attenuates angiotensin II hypertension and kidney injury.
Academic Article 20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Academic Article Epoxyeicosatrienoic Acid Analog and 20-HETE Antagonist Combination Prevent Hypertension Development in Spontaneously Hypertensive Rats.
Academic Article Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME.
Academic Article Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids.
Academic Article Epoxyeicosatrienoic acids, 20-hydroxyeicosatetraenoic acid, and renal microvascular function.
Academic Article Decreased renal cytochrome P450 2C enzymes and impaired vasodilation are associated with angiotensin salt-sensitive hypertension.
Academic Article Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension.
Academic Article Epoxyeicosatrienoic acids, hypertension, and kidney injury.
Academic Article p66Shc regulates renal vascular tone in hypertension-induced nephropathy.
Academic Article Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Academic Article Regulation of Cardiac Mast Cell Maturation and Function by the Neurokinin-1 Receptor in the Fibrotic Heart.
Academic Article Orally active epoxyeicosatrienoic acid analogs in hypertension and renal injury.
Academic Article Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure.
Academic Article Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension.
Academic Article Adaptations of the renal microcirculation to hypertension.
Academic Article Soluble epoxide hydrolase inhibition and peroxisome proliferator activated receptor ? agonist improve vascular function and decrease renal injury in hypertensive obese rats.
Academic Article Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet.
Academic Article Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats.
Academic Article Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension.
Academic Article Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.
Academic Article Anti-inflammatory effects of ?-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension.
Academic Article Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice.
Academic Article Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats.
Academic Article Downregulation of renal CYP-derived eicosanoid synthesis in rats with diet-induced hypertension.
Academic Article Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension.
Academic Article Simvastatin and tempol protect against endothelial dysfunction and renal injury in a model of obesity and hypertension.
Academic Article Orally active epoxyeicosatrienoic acid analog attenuates kidney injury in hypertensive Dahl salt-sensitive rat.
Academic Article Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats.
Academic Article The epoxyeicosatrienoic acid analog PVPA ameliorates cyclosporine-induced hypertension and renal injury in rats.
Academic Article ACE Inhibition and Bradykinin-Mediated Renal Vascular Responses: EDHF Involvement.
Academic Article Combined treatment with epoxyeicosatrienoic acid analog and 20-hydroxyeicosatetraenoic acid antagonist provides substantial hypotensive effect in spontaneously hypertensive rats.
Academic Article Salt-sensitive hypertension after exposure to angiotensin is associated with inability to upregulate renal epoxygenases.
Academic Article Obesity induced renal oxidative stress contributes to renal injury in salt-sensitive hypertension.
Academic Article Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage.
Academic Article The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt.
Academic Article Epoxy Fatty Acids: From Salt Regulation to Kidney and Cardiovascular Therapeutics: 2019 Lewis K. Dahl Memorial Lecture.
Academic Article Epoxyeicosatrienoic acid analogue mitigates kidney injury in a rat model of radiation nephropathy.
Academic Article Fructose stimulates Na/H exchange activity and sensitizes the proximal tubule to angiotensin II.
Academic Article Elevated arterial pressure impairs autoregulation independently of AT(1) receptor activation.
Academic Article Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.
Academic Article Ang II accumulation in rat renal endosomes during Ang II-induced hypertension: role of AT(1) receptor.
Academic Article The Soluble Epoxide Hydrolase Inhibitor AR9281 Decreases Blood Pressure, Ameliorates Renal Injury and Improves Vascular Function in Hypertension.
Academic Article 20-hydroxyeicosatetraenoic acid and angiotensin: a positive feedback system to cause hypertension.
Academic Article Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.
Academic Article Orally Active Epoxyeicosatrienoic Acid Analogs.
Academic Article Adenosine2A receptors and epoxyeicosatrienoic acids: a recipe for salt and blood pressure regulation.
Academic Article Unraveling the Mystery of Goldblatt Hypertension.
Academic Article Azilsartan decreases renal and cardiovascular injury in the spontaneously hypertensive obese rat.
Academic Article Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Academic Article Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension.
Academic Article Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.
Academic Article Peroxisome proliferator-activated receptor-alpha activation reduces salt-dependent hypertension during chronic endothelin B receptor blockade.
Academic Article Impaired Ca2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension.
Academic Article Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats.
Academic Article An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension.
Academic Article Targeting epoxides for organ damage in hypertension.
Academic Article Angiotensin II hypertension is attenuated in interleukin-6 knockout mice.
Academic Article An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats.
Academic Article Loss of Chloride Channel 6 (CLC-6) Affects Vascular Smooth Muscle Contractility and Arterial Stiffness via Alterations to Golgi Calcium Stores.
Academic Article Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension.
Academic Article Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria.
Academic Article A novel dual PPAR-? agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes.

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  • Hypertension