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Juvvadi, Praveen

One or more keywords matched the following items that are connected to Juvvadi, Praveen

Item Type	Name
Concept	Tacrolimus
Concept	Tacrolimus Binding Protein 1A
Academic Article	In vitro activity of calcineurin and heat shock protein 90 Inhibitors against Aspergillus fumigatus azole- and echinocandin-resistant strains.
Academic Article	Heat shock protein 90 is required for conidiation and cell wall integrity in Aspergillus fumigatus.
Academic Article	Characterization of the FKBP12-Encoding Genes in Aspergillus fumigatus.
Academic Article	Novel motif in calcineurin catalytic subunit is required for septal localization of calcineurin in Aspergillus fumigatus.
Academic Article	Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function.
Academic Article	Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach.
Academic Article	Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
Academic Article	FKBP12 dimerization mutations effect FK506 binding and differentially alter calcineurin inhibition in the human pathogen Aspergillus fumigatus.
Academic Article	Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs.
Academic Article	Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus.

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