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keywords Protein Biochemistry
keywords Structures, Secondary Protein
keywords Protein Synthesis
overview Kiran Kumar Adepu obtained his Ph.D. degree in Biotechnology (specialization in protein chemistry and enzymology) from one of the globally renowned Institutes, Indian Institute of Technology (IIT) Guwahati. He has a vast Postdoctoral Research training from Pennsylvania State University, Pennsylvania and Brookhaven National Laboratory, New York, NY, USA focusing on different metabolic and cellular metalloproteins: their biochemical, molecular, biophysical & structure-function relation studies. Before Joining UAMS, He worked with Biotechnology & Probiotic Industries as Group Leader - Enzyme Development, Head of Research and Development & Director (Technical). He was also associated with Non-profit Research Organization for several years in different research & administrative positions (Senior Scientist, Principal Scientist & Head of the Division) leading a large group of research scientists, team members, technical and non-technical teams. He has developed several bio-based technologies and obtained patents, research grants related to bioenergy, food and nutrition. Since 2019, Dr. Adepu is recognized as one of the "Top 2% Worlds Most Influential Researchers" in the field of Biotechnology.
research overview I have a strong record of formal training in basic biochemistry from my bachelor and master’s programs. As a graduate in biotechnology, I was trained in developing complex membrane-bound redox proteins from microbial sources, characterize its functional properties towards its potential applications, synthesis of industrially important products, enzyme-based biosensors and biofuel cells. During my postdoctoral training, I had gained immense experience in several biochemical, biophysical, molecular expression tools, focused on protein crystallization of metallo-proteins, denovo crystal structure determination of novel iron-sulfur protein containing both eukaryotic and prokaryotic subunits from the archaebacterial with key cellular functions. Being part of industrial research, I was involved in design and development of cellulose degrading enzymes, novel green solvents, micro-algae and its deployment towards bio-renewable energy research, and probiotic gut microbiota towards increasing innate health immunity. Currently, I am actively involved in research projects pertaining to muscle physiology, work that complements collaborative studies examining protein-ligand interactions of different cellular metabolites. Having broad experience in multi- and inter-disciplinary research skills in structural and functional biology, I am able to collaborate with investigators in various fields. My focus is to develop in vitro based research experimentations in understanding cellular physiology and approaches that provide a strong scientific premise connecting in silico and in vivo research. Thus, my overall research program addresses research, design, development and deployment. This unique skillset and approach will be applied in the current application considering its focus on myoglobin structural-functional biochemistry and implications toward intermediary metabolism of cellular metabolites in pathophysiological conditions.

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  • Protein
  • Biochemistry