 Cyclodextrins
"Cyclodextrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the action of cyclodextrin glucanotransferase on starch or similar substrates. The enzyme is produced by certain species of Bacillus. Cyclodextrins form inclusion complexes with a wide variety of substances.
| Descriptor ID |
D003505
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| MeSH Number(s) |
D04.345.103 D09.698.365.855.400.375
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclodextrins".
Below are MeSH descriptors whose meaning is more specific than "Cyclodextrins".
This graph shows the total number of publications written about "Cyclodextrins" by people in UAMS Profiles by year, and whether "Cyclodextrins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 | | 2004 | 1 | 2 | 3 | | 2003 | 0 | 2 | 2 | | 1998 | 0 | 3 | 3 |
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Below are the most recent publications written about "Cyclodextrins" by people in Profiles over the past ten years.
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Al-Husseini JK, Fong EM, Wang C, Ha JH, Upreti M, Chiarelli PA, Johal MS. Ex Vivo Drug Screening Assay with Artificial Membranes: Characterizing Cholesterol Desorbing Competencies of Beta-Cyclodextrins. Langmuir. 2023 09 12; 39(36):12590-12598.
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Krasner CN, Campos SM, Young CL, Chadda KR, Lee H, Birrer MJ, Horowitz NS, Konstantinopoulos PA, D'Ascanio AM, Matulonis UA, Penson RT. Sequential Phase II clinical trials evaluating CRLX101 as monotherapy and in combination with bevacizumab in recurrent ovarian cancer. Gynecol Oncol. 2021 09; 162(3):661-666.
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Jambhekar SS, Breen P. Cyclodextrins in pharmaceutical formulations I: structure and physicochemical properties, formation of complexes, and types of complex. Drug Discov Today. 2016 Feb; 21(2):356-62.
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Jambhekar SS, Breen P. Cyclodextrins in pharmaceutical formulations II: solubilization, binding constant, and complexation efficiency. Drug Discov Today. 2016 Feb; 21(2):363-8.
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Pham E, Birrer MJ, Eliasof S, Garmey EG, Lazarus D, Lee CR, Man S, Matulonis UA, Peters CG, Xu P, Krasner C, Kerbel RS. Translational impact of nanoparticle-drug conjugate CRLX101 with or without bevacizumab in advanced ovarian cancer. Clin Cancer Res. 2015 Feb 15; 21(4):808-18.
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