 Amyloidosis
"Amyloidosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
| Descriptor ID |
D000686
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| MeSH Number(s) |
C18.452.845.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Amyloidosis".
Below are MeSH descriptors whose meaning is more specific than "Amyloidosis".
This graph shows the total number of publications written about "Amyloidosis" by people in UAMS Profiles by year, and whether "Amyloidosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2023 | 2 | 0 | 2 | | 2022 | 2 | 0 | 2 | | 2021 | 3 | 0 | 3 | | 2020 | 3 | 0 | 3 | | 2018 | 1 | 1 | 2 | | 2017 | 1 | 1 | 2 | | 2016 | 6 | 1 | 7 | | 2014 | 4 | 0 | 4 | | 2013 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2010 | 1 | 0 | 1 | | 2009 | 1 | 2 | 3 | | 2007 | 1 | 1 | 2 | | 2005 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1992 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amyloidosis" by people in Profiles over the past ten years.
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Wong S, West ME, Morgan GJ. Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains. Protein Sci. 2024 Mar; 33(3):e4871.
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Chakraborty R, Bhutani D, Maurer MS, Mohan M, Lentzsch S, D'Souza A. Safety and efficacy of teclistamab in systemic immunoglobulin light chain amyloidosis. Blood Cancer J. 2023 11 27; 13(1):172.
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Yan NL, Morgan GJ, Petrassi HM, Wilson IA, Kelly JW. Pharmacological stabilization of the native state of full-length immunoglobulin light chains to treat light chain amyloidosis. Curr Opin Chem Biol. 2023 08; 75:102319.
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Gao YJ, Shen KN, Chang L, Feng J, Mao YY, Zhang L, Cao XX, Zhou DB, Li J. Prevalence, clinical characteristics and treatment outcome of factor X deficiency in a consecutive cohort of primary light-chain amyloidosis. Leuk Res. 2022 09; 120:106917.
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Gao YJ, Shen KN, Miao HL, Tian Z, Feng J, Zhang L, Cao XX, Zhou DB, Li J. A retrospective study of ultrahigh-risk (Mayo 2004 stage IIIb) AL amyloidosis and identification of predictors related to extremely early death. Leuk Lymphoma. 2022 07; 63(7):1758-1761.
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Morgan GJ. Transient disorder along pathways to amyloid. Biophys Chem. 2022 02; 281:106711.
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Shen KN, Fu WJ, Wu Y, Dong YJ, Huang ZX, Wei YQ, Li CR, Sun CY, Chen Y, Miao HL, Zhang YL, Cao XX, Zhou DB, Li J. Doxycycline Combined With Bortezomib-Cyclophosphamide-Dexamethasone Chemotherapy for Newly Diagnosed Cardiac Light-Chain Amyloidosis: A Multicenter Randomized Controlled Trial. Circulation. 2022 01 04; 145(1):8-17.
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Chyra Z, Sevcikova T, Vojta P, Puterova J, Brozova L, Growkova K, Filipova J, Zatopkova M, Grosicki S, Barchnicka A, Jedrzejczak WW, Waszczuk-Gajda A, Jungova A, Mikulasova A, Hajduch M, Mokrejs M, Pour L, Stork M, Harvanova L, Mistrik M, Mikala G, Robak P, Czyz A, Debski J, Usnarska-Zubkiewicz L, Jurczyszyn A, Stejskal L, Morgan G, Kryukov F, Budinska E, Simicek M, Jelinek T, Hrdinka M, Hajek R. Heterogenous mutation spectrum and deregulated cellular pathways in aberrant plasma cells underline molecular pathology of light-chain amyloidosis. Haematologica. 2021 02 01; 106(2):601-604.
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Shen KN, Miao HL, Zhang CL, Feng J, Zhang L, Cao XX, Zhou DB, Wei S, Li J. Posttreatment dFLC less than 10?mg/L predicts superior organ response and longer time to next treatment in newly diagnosed light-chain amyloidosis patients treated with bortezomib. Leuk Lymphoma. 2021 04; 62(4):874-882.
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Gokden M. Amyloid Deposition in the Brain. Arch Pathol Lab Med. 2020 10 01; 144(10):1162-1163.
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Pezhouh MK, Burgart LJ, Chiu K, Cohen DA, Hutchings DA, Sanderson SO, Shirazi M, Stanich PP, VandenBussche CJ, Voltaggio L, Willhoit ED, Xue Y, Arnold CA. Characterization of Novel Injectable Lifting Agents Used in Colonic Polyp Removal: An Emerging Amyloid Mimic. Am J Surg Pathol. 2020 06; 44(6):793-798.
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Iadanza MG, Jackson MP, Hewitt EW, Ranson NA, Radford SE. A new era for understanding amyloid structures and disease. Nat Rev Mol Cell Biol. 2018 12; 19(12):755-773.
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Lundeen TF, Seibyl JP, Covington MF, Eshghi N, Kuo PH. Signs and Artifacts in Amyloid PET. Radiographics. 2018 Nov-Dec; 38(7):2123-2133.
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Jackson MP, Hewitt EW. Why are Functional Amyloids Non-Toxic in Humans? Biomolecules. 2017 09 22; 7(4).
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Cao XX, Meng Q, Cai H, He TH, Zhang CL, Su W, Sun J, Li Y, Xu W, Zhou DB, Li J. Detection of MYD88 L265P and WHIM-like CXCR4 mutation in patients with IgM monoclonal gammopathy related disease. Ann Hematol. 2017 Jun; 96(6):971-976.
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Pandey T, Alapati S, Wadhwa V, Edupuganti MM, Gurram P, Lensing S, Jambhekar K. Evaluation of Myocardial Strain in Patients With Amyloidosis Using Cardiac Magnetic Resonance Feature Tracking. Curr Probl Diagn Radiol. 2017 Jul - Aug; 46(4):288-294.
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Bhatti S, Vallurupalli S, Ambach S, Magier A, Watts E, Truong V, Hakeem A, Mazur W. Myocardial strain pattern in patients with cardiac amyloidosis secondary to multiple myeloma: a cardiac MRI feature tracking study. Int J Cardiovasc Imaging. 2018 Jan; 34(1):27-33.
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Raina S, Lensing SY, Nairooz RS, Pothineni NV, Hakeem A, Bhatti S, Pandey T. Prognostic Value of Late?Gadolinium?Enhancement CMR in?Systemic Amyloidosis. JACC Cardiovasc Imaging. 2016 11; 9(11):1267-1277.
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Bhatti S, Watts E, Syed F, Vallurupalli S, Pandey T, Jambekar K, Mazur W, Hakeem A. Clinical and prognostic utility of cardiovascular magnetic resonance imaging in myeloma patients with suspected cardiac amyloidosis. Eur Heart J Cardiovasc Imaging. 2016 Sep; 17(9):970-7.
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Larsen CP, Beggs ML, Wilson JD, Lathrop SL. Prevalence and organ distribution of leukocyte chemotactic factor 2 amyloidosis (ALECT2) among decedents in New Mexico. Amyloid. 2016 Jun; 23(2):119-23.
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Bhutani M, Shahid Z, Schnebelen A, Alapat D, Usmani SZ. Cutaneous manifestations of multiple myeloma and other plasma cell proliferative disorders. Semin Oncol. 2016 06; 43(3):395-400.
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Chow E, Shahid Z, Smith ET, Kamionek M, Usmani SZ. Successful Treatment of Hepatitis C Infection While Receiving Concurrent Chemotherapy for AL Amyloidosis. Clin Lymphoma Myeloma Leuk. 2016 Apr; 16(4):237-9.
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