 Eflornithine
"Eflornithine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inhibitor of ornithine decarboxylase, the rate limiting enzyme of the polyamine biosynthetic pathway.
| Descriptor ID |
D000518
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| MeSH Number(s) |
D12.125.068.665.340 D12.125.095.765.340
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| Concept/Terms |
Eflornithine- Eflornithine
- alpha-Difluoromethyl Ornithine
- Ornithine, alpha-Difluoromethyl
- alpha Difluoromethyl Ornithine
- alpha-Difluoromethylornithine
- alpha Difluoromethylornithine
Vaniqa- Vaniqa
- Women First Brand of Eflornithine Hydrochloride
Eflornithine Hydrochloride- Eflornithine Hydrochloride
- Hydrochloride, Eflornithine
- Eflornithine Monohydrochloride, Monohydrate
- Monohydrochloride, Monohydrate Eflornithine
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Below are MeSH descriptors whose meaning is more general than "Eflornithine".
Below are MeSH descriptors whose meaning is more specific than "Eflornithine".
This graph shows the total number of publications written about "Eflornithine" by people in UAMS Profiles by year, and whether "Eflornithine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Eflornithine" by people in Profiles over the past ten years.
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Sholler GLS, Ferguson W, Bergendahl G, Bond JP, Neville K, Eslin D, Brown V, Roberts W, Wada RK, Oesterheld J, Mitchell D, Foley J, Parikh NS, Eshun F, Zage P, Rawwas J, Sencer S, Pankiewicz D, Quinn M, Rich M, Junewick J, Kraveka JM. Maintenance DFMO Increases Survival in High Risk Neuroblastoma. Sci Rep. 2018 09 27; 8(1):14445.
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Saulnier Sholler GL, Gerner EW, Bergendahl G, MacArthur RB, VanderWerff A, Ashikaga T, Bond JP, Ferguson W, Roberts W, Wada RK, Eslin D, Kraveka JM, Kaplan J, Mitchell D, Parikh NS, Neville K, Sender L, Higgins T, Kawakita M, Hiramatsu K, Moriya SS, Bachmann AS. A Phase I Trial of DFMO Targeting Polyamine Addiction in Patients with Relapsed/Refractory Neuroblastoma. PLoS One. 2015; 10(5):e0127246.
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Allen AR, Eilertson K, Sharma S, Baure J, Allen B, Leu D, Rosi S, Raber J, Huang TT, Fike JR. Delayed administration of alpha-difluoromethylornithine prevents hippocampus-dependent cognitive impairment after single and combined injury in mice. Radiat Res. 2014 Nov; 182(5):489-98.
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