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Mutation hotspots in the p53 gene in tumors of different origin: correlation with evolutionary conservation and signs of positive selection.
Glazko GV, Koonin EV, Rogozin IB. Mutation hotspots in the p53 gene in tumors of different origin: correlation with evolutionary conservation and signs of positive selection. Biochim Biophys Acta. 2004 Aug 12; 1679(2):95-106.
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PubMed
subject areas
Amino Acid Sequence
Amino Acid Substitution
Animals
Base Sequence
Binding Sites
CpG Islands
DNA-Binding Proteins
Evolution, Molecular
Genes, p53
Genes, Tumor Suppressor
Germ-Line Mutation
Humans
Molecular Sequence Data
Mutation
Neoplasms
Nuclear Proteins
Phosphoproteins
Phylogeny
Selection, Genetic
Sequence Alignment
Statistics as Topic
Trans-Activators
Transcription Factors
Tumor Suppressor Protein p53
Tumor Suppressor Proteins
authors with profiles
Galina Glazko