DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells.

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DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells.

Singh KP, Treas J, Tyagi T, Gao W. DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells. Cancer Lett. 2012 Mar; 316(1):62-9.

View in: PubMed

subject areas

Apoptosis
Azacitidine
Breast Neoplasms
Cell Cycle
Cell Growth Processes
DNA Methylation
DNA Mismatch Repair
DNA Repair
Drug Interactions
Epigenesis, Genetic
Estradiol
Female
Gene Expression Regulation, Neoplastic
Humans
Promoter Regions, Genetic