Improving the inhibitory activity of arylidenaminoguanidine compounds at the N-methyl-D-aspartate receptor complex from a recursive computational-experimental structure-activity relationship study.

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Improving the inhibitory activity of arylidenaminoguanidine compounds at the N-methyl-D-aspartate receptor complex from a recursive computational-experimental structure-activity relationship study.

Ring JR, Zheng F, Haubner AJ, Littleton JM, Crooks PA. Improving the inhibitory activity of arylidenaminoguanidine compounds at the N-methyl-D-aspartate receptor complex from a recursive computational-experimental structure-activity relationship study. Bioorg Med Chem. 2013 Apr 01; 21(7):1764-74.

View in: PubMed

subject areas

Computer Simulation
Guanidines
Humans
Least-Squares Analysis
Models, Biological
Quantitative Structure-Activity Relationship
Receptors, N-Methyl-D-Aspartate

authors with profiles

Peter Crooks