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Connection

Gunnar Boysen to Humans

This is a "connection" page, showing publications Gunnar Boysen has written about Humans.

 
Connection Strength
  
 
 
0.602
  
  1. Jamshidi-Parsian A, Jenkins SV, Tran A, Bragg A, Davis R, Griffin C, Siegel E, Dings RPM, Griffin RJ, Boysen G. CB-839 induces reversible dormancy in lung tumor-cells. Eur J Pharmacol. 2024 Nov 05; 982:176912.
    View in: PubMed
    Score: 0.040
  2. Boysen G, Rusyn I, Chiu WA, Wright FA. Characterization of population variability of 1,3-butadiene derived protein adducts in humans and mice. Regul Toxicol Pharmacol. 2022 Jul; 132:105171.
    View in: PubMed
    Score: 0.034
  3. Nellis M, Caperton CO, Liu K, Tran V, Go YM, Hallberg LM, Ameredes BT, Jones DP, Boysen G. Lung metabolome of 1,3-butadiene exposed Collaborative Cross mice reflects metabolic phenotype of human lung cancer. Toxicology. 2021 11; 463:152987.
    View in: PubMed
    Score: 0.033
  4. Boysen G, Arora R, Degner A, Vevang KR, Chao C, Rodriguez F, Walmsley SJ, Erber L, Tretyakova NY, Peterson LA. Effects of GSTT1 Genotype on the Detoxification of 1,3-Butadiene Derived Diepoxide and Formation of Promutagenic DNA-DNA Cross-Links in Human Hapmap Cell Lines. Chem Res Toxicol. 2021 01 18; 34(1):119-131.
    View in: PubMed
    Score: 0.031
  5. Boysen G, Shimoni A, Danylesko I, Varda-Bloom N, Nagler A. A simplified method for detection of N-terminal valine adducts in patients receiving treosulfan. Rapid Commun Mass Spectrom. 2019 Nov 15; 33(21):1635-1642.
    View in: PubMed
    Score: 0.029
  6. Boysen G, Jamshidi-Parsian A, Davis MA, Siegel ER, Simecka CM, Kore RA, Dings RPM, Griffin RJ. Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice. Int J Radiat Biol. 2019 04; 95(4):436-442.
    View in: PubMed
    Score: 0.027
  7. Sappington D, Helms S, Siegel E, Penney RB, Jeffus S, Bartter T, Bartter T, Boysen G. Diagnosis of lung tumor types based on metabolomic profiles in lymph node aspirates. Cancer Treat Res Commun. 2018; 14:1-6.
    View in: PubMed
    Score: 0.025
  8. Boysen G. The Glutathione Conundrum: Stoichiometric Disconnect between Its Formation and Oxidative Stress. Chem Res Toxicol. 2017 05 15; 30(5):1113-1116.
    View in: PubMed
    Score: 0.024
  9. Sappington DR, Siegel ER, Hiatt G, Desai A, Penney RB, Jamshidi-Parsian A, Griffin RJ, Boysen G. Glutamine drives glutathione synthesis and contributes to radiation sensitivity of A549 and H460 lung cancer cell lines. Biochim Biophys Acta. 2016 Apr; 1860(4):836-43.
    View in: PubMed
    Score: 0.022
  10. Hartman JH, Miller GP, Boysen G. Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity. Toxicology. 2014 Apr 06; 318:51-8.
    View in: PubMed
    Score: 0.019
  11. Goel S, Evans-Johnson JA, Georgieva NI, Boysen G. Exposure profiling of reactive compounds in complex mixtures. Toxicology. 2013 Nov 16; 313(2-3):145-150.
    View in: PubMed
    Score: 0.018
  12. Bogusiewicz A, Horvath TD, Stratton SL, Mock DM, Boysen G. Measurement of acylcarnitine substrate to product ratios specific to biotin-dependent carboxylases offers a combination of indicators of biotin status in humans. J Nutr. 2012 Sep; 142(9):1621-5.
    View in: PubMed
    Score: 0.017
  13. Boysen G, Georgieva NI, Bordeerat NK, Sram RJ, Vacek P, Albertini RJ, Swenberg JA. Formation of 1,2:3,4-diepoxybutane-specific hemoglobin adducts in 1,3-butadiene exposed workers. Toxicol Sci. 2012 Jan; 125(1):30-40.
    View in: PubMed
    Score: 0.016
  14. Horvath TD, Matthews NI, Stratton SL, Mock DM, Boysen G. Measurement of 3-hydroxyisovaleric acid in urine from marginally biotin-deficient humans by UPLC-MS/MS. Anal Bioanal Chem. 2011 Nov; 401(9):2805-10.
    View in: PubMed
    Score: 0.016
  15. Boysen G, Collins LB, Liao S, Luke AM, Pachkowski BF, Watters JL, Swenberg JA. Analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine by ultra high pressure liquid chromatography-heat assisted electrospray ionization-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Feb 01; 878(3-4):375-80.
    View in: PubMed
    Score: 0.015
  16. Boysen G, Pachkowski BF, Nakamura J, Swenberg JA. The formation and biological significance of N7-guanine adducts. Mutat Res. 2009 Aug; 678(2):76-94.
    View in: PubMed
    Score: 0.014
  17. Esther CR, Jasin HM, Collins LB, Swenberg JA, Boysen G. A mass spectrometric method to simultaneously measure a biomarker and dilution marker in exhaled breath condensate. Rapid Commun Mass Spectrom. 2008; 22(5):701-5.
    View in: PubMed
    Score: 0.013
  18. Boysen G, Scarlett CO, Temple B, Combs TP, Brooks NL, Borchers CH, Swenberg JA. Identification of covalent modifications in P450 2E1 by 1,2-epoxy-3-butene in vitro. Chem Biol Interact. 2007 Mar 20; 166(1-3):170-5.
    View in: PubMed
    Score: 0.012
  19. Boysen G, Georgieva NI, Upton PB, Walker VE, Swenberg JA. N-terminal globin adducts as biomarkers for formation of butadiene derived epoxides. Chem Biol Interact. 2007 Mar 20; 166(1-3):84-92.
    View in: PubMed
    Score: 0.012
  20. Boysen G, Georgieva NI, Upton PB, Jayaraj K, Li Y, Walker VE, Swenberg JA. Analysis of diepoxide-specific cyclic N-terminal globin adducts in mice and rats after inhalation exposure to 1,3-butadiene. Cancer Res. 2004 Dec 01; 64(23):8517-20.
    View in: PubMed
    Score: 0.010
  21. Wang X, Sato AY, Marino S, Akel N, Boysen G, Basnakian AG, Bellido TM, Li HY. Generation of BT-Amide, a Bone-Targeted Pyk2 Inhibitor, Effective via Oral Administration, for the Prevention of Glucocorticoid-Induced Bone Loss. J Med Chem. 2024 Nov 28; 67(22):20708-20720.
    View in: PubMed
    Score: 0.010
  22. Jenkins SV, Shah S, Jamshidi-Parsian A, Mortazavi A, Kristian H, Boysen G, Vang KB, Griffin RJ, Rajaram N, Dings RPM. Acquired Radiation Resistance Induces Thiol-dependent Cisplatin Cross-resistance. Radiat Res. 2024 02 01; 201(2):174-187.
    View in: PubMed
    Score: 0.010
  23. Wongsurawat T, Jenjaroenpun P, Anekwiang P, Arigul T, Thongrattana W, Jamshidi-Parsian A, Boysen G, Suriyaphol P, Suktitipat B, Srirabheebhat P, Cheunsuchon P, Tanboon J, Nookaew I, Sathornsumetee S. Exploiting nanopore sequencing for characterization and grading of IDH-mutant gliomas. Brain Pathol. 2024 01; 34(1):e13203.
    View in: PubMed
    Score: 0.009
  24. Boysen G, Hecht SS. Analysis of DNA and protein adducts of benzo[a]pyrene in human tissues using structure-specific methods. Mutat Res. 2003 Jan; 543(1):17-30.
    View in: PubMed
    Score: 0.009
  25. Pujari SS, Jokipii Krueger CC, Chao C, Hutchins S, Hurben AK, Boysen G, Tretyakova N. DEB-FAPy-dG Adducts of 1,3-Butadiene: Synthesis, Structural Characterization, and Formation in 1,2,3,4-Diepoxybutane Treated DNA. Chemistry. 2022 Jan 13; 28(3):e202103245.
    View in: PubMed
    Score: 0.008
  26. Schleiff MA, Crosby S, Blue M, Schleiff BM, Boysen G, Miller GP. CYP2C9 and 3A4 play opposing roles in bioactivation and detoxification of diphenylamine NSAIDs. Biochem Pharmacol. 2021 12; 194:114824.
    View in: PubMed
    Score: 0.008
  27. Schleiff MA, Payakachat S, Schleiff BM, Swamidass SJ, Boysen G, Miller GP. Impacts of diphenylamine NSAID halogenation on bioactivation risks. Toxicology. 2021 06 30; 458:152832.
    View in: PubMed
    Score: 0.008
  28. Jenjaroenpun P, Wongsurawat T, Wadley TD, Wassenaar TM, Liu J, Dai Q, Wanchai V, Akel NS, Jamshidi-Parsian A, Franco AT, Boysen G, Jennings ML, Ussery DW, He C, Nookaew I. Decoding the epitranscriptional landscape from native RNA sequences. Nucleic Acids Res. 2021 01 25; 49(2):e7.
    View in: PubMed
    Score: 0.008
  29. Schleiff MA, Flynn NR, Payakachat S, Schleiff BM, Pinson AO, Province DW, Swamidass SJ, Boysen G, Miller GP. Significance of Multiple Bioactivation Pathways for Meclofenamate as Revealed through Modeling and Reaction Kinetics. Drug Metab Dispos. 2021 02; 49(2):133-141.
    View in: PubMed
    Score: 0.008
  30. Pinson AO, Pouncey DL, Schleiff MA, Fantegrossi WE, Prather PL, Radominska-Pandya A, Boysen G, Miller GP. Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics. Molecules. 2020 Oct 20; 25(20).
    View in: PubMed
    Score: 0.008
  31. Davis MA, Barnette DA, Flynn NR, Pidugu AS, Swamidass SJ, Boysen G, Miller GP. CYP2C19 and 3A4 Dominate Metabolic Clearance and Bioactivation of Terbinafine Based on Computational and Experimental Approaches. Chem Res Toxicol. 2019 06 17; 32(6):1151-1164.
    View in: PubMed
    Score: 0.007
  32. Pouncey DL, Hartman JH, Moore PC, Dillinger DJ, Dickerson KW, Sappington DR, Smith ES, Boysen G, Miller GP. Novel isomeric metabolite profiles correlate with warfarin metabolism phenotype during maintenance dosing in a pilot study of 29 patients. Blood Coagul Fibrinolysis. 2018 Nov; 29(7):602-612.
    View in: PubMed
    Score: 0.007
  33. Barnette DA, Davis MA, Dang NL, Pidugu AS, Hughes T, Swamidass SJ, Boysen G, Miller GP. Lamisil (terbinafine) toxicity: Determining pathways to bioactivation through computational and experimental approaches. Biochem Pharmacol. 2018 10; 156:10-21.
    View in: PubMed
    Score: 0.007
  34. Bogusiewicz A, Boysen G, Mock DM. In HepG2 cells, coexisting carnitine deficiency masks important indicators of marginal biotin deficiency. J Nutr. 2015 Jan; 145(1):32-40.
    View in: PubMed
    Score: 0.005
  35. Pugh CP, Pouncey DL, Hartman JH, Nshimiyimana R, Desrochers LP, Goodwin TE, Boysen G, Miller GP. Multiple UDP-glucuronosyltransferases in human liver microsomes glucuronidate both R- and S-7-hydroxywarfarin into two metabolites. Arch Biochem Biophys. 2014 Dec 15; 564:244-53.
    View in: PubMed
    Score: 0.005
  36. Edavana VK, Dhakal IB, Williams S, Penney R, Boysen G, Yao-Borengasser A, Kadlubar S. Potential role of UGT1A4 promoter SNPs in anastrozole pharmacogenomics. Drug Metab Dispos. 2013 Apr; 41(4):870-7.
    View in: PubMed
    Score: 0.005
  37. Hartman JH, Boysen G, Miller GP. Cooperative effects for CYP2E1 differ between styrene and its metabolites. Xenobiotica. 2013 Sep; 43(9):755-64.
    View in: PubMed
    Score: 0.005
  38. Kim SY, Kang JY, Hartman JH, Park SH, Jones DR, Yun CH, Boysen G, Miller GP. Metabolism of R- and S-warfarin by CYP2C19 into four hydroxywarfarins. Drug Metab Lett. 2012 Sep 01; 6(3):157-64.
    View in: PubMed
    Score: 0.004
  39. Hartman JH, Boysen G, Miller GP. CYP2E1 metabolism of styrene involves allostery. Drug Metab Dispos. 2012 Oct; 40(10):1976-83.
    View in: PubMed
    Score: 0.004
  40. Stratton SL, Henrich CL, Matthews NI, Bogusiewicz A, Dawson AM, Horvath TD, Owen SN, Boysen G, Moran JH, Mock DM. Marginal biotin deficiency can be induced experimentally in humans using a cost-effective outpatient design. J Nutr. 2012 Jan; 142(1):22-6.
    View in: PubMed
    Score: 0.004
  41. Mock DM, Stratton SL, Horvath TD, Bogusiewicz A, Matthews NI, Henrich CL, Dawson AM, Spencer HJ, Owen SN, Boysen G, Moran JH. Urinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in marginally biotin-deficient humans. J Nutr. 2011 Nov; 141(11):1925-30.
    View in: PubMed
    Score: 0.004
  42. Jones DR, Boysen G, Miller GP. Novel multi-mode ultra performance liquid chromatography-tandem mass spectrometry assay for profiling enantiomeric hydroxywarfarins and warfarin in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 May 01; 879(15-16):1056-62.
    View in: PubMed
    Score: 0.004
  43. Jones DR, Kim SY, Boysen G, Yun CH, Miller GP. Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin. Drug Metab Lett. 2010 Dec; 4(4):213-9.
    View in: PubMed
    Score: 0.004
  44. Swenberg JA, Bordeerat NK, Boysen G, Carro S, Georgieva NI, Nakamura J, Troutman JM, Upton PB, Albertini RJ, Vacek PM, Walker VE, Sram RJ, Goggin M, Tretyakova N. 1,3-Butadiene: Biomarkers and application to risk assessment. Chem Biol Interact. 2011 Jun 30; 192(1-2):150-4.
    View in: PubMed
    Score: 0.004
  45. Watters JL, Satia JA, da Costa KA, Boysen G, Collins LB, Morrow JD, Milne GL, Swenberg JA. Comparison of three oxidative stress biomarkers in a sample of healthy adults. Biomarkers. 2009 Dec; 14(8):587-95.
    View in: PubMed
    Score: 0.004
  46. Esther CR, Boysen G, Olsen BM, Collins LB, Ghio AJ, Swenberg JW, Boucher RC. Mass spectrometric analysis of biomarkers and dilution markers in exhaled breath condensate reveals elevated purines in asthma and cystic fibrosis. Am J Physiol Lung Cell Mol Physiol. 2009 Jun; 296(6):L987-93.
    View in: PubMed
    Score: 0.003
  47. Swenberg JA, Fryar-Tita E, Jeong YC, Boysen G, Starr T, Walker VE, Albertini RJ. Biomarkers in toxicology and risk assessment: informing critical dose-response relationships. Chem Res Toxicol. 2008 Jan; 21(1):253-65.
    View in: PubMed
    Score: 0.003
  48. Swenberg JA, Boysen G, Georgieva N, Bird MG, Lewis RJ. Future directions in butadiene risk assessment and the role of cross-species internal dosimetry. Chem Biol Interact. 2007 Mar 20; 166(1-3):78-83.
    View in: PubMed
    Score: 0.003
  49. Albertini RJ, Sram RJ, Vacek PM, Lynch J, Rossner P, Nicklas JA, McDonald JD, Boysen G, Georgieva N, Swenberg JA. Molecular epidemiological studies in 1,3-butadiene exposed Czech workers: female-male comparisons. Chem Biol Interact. 2007 Mar 20; 166(1-3):63-77.
    View in: PubMed
    Score: 0.003
  50. Georgieva NI, Boysen G, Upton PB, Jayaraj K, Gold A, Swenberg JA. Quantitative analysis of N-terminal valine peptide adducts specific for 1,2-epoxy-3-butene. Chem Biol Interact. 2007 Mar 20; 166(1-3):219-25.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.