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Connection

Gerald Dienel to Glucose

This is a "connection" page, showing publications Gerald Dienel has written about Glucose.

 
Connection Strength
  
 
 
9.559
  
  1. Rothman DL, Behar KL, Dienel GA. Mechanistic stoichiometric relationship between the rates of neurotransmission and neuronal glucose oxidation: Reevaluation of and alternatives to the pseudo-malate-aspartate shuttle model. J Neurochem. 2024 05; 168(5):555-591.
    View in: PubMed
    Score: 0.715
  2. Dienel GA, Rothman DL. Reevaluation of Astrocyte-Neuron Energy Metabolism with Astrocyte Volume Fraction Correction: Impact on Cellular Glucose Oxidation Rates, Glutamate-Glutamine Cycle Energetics, Glycogen Levels and Utilization Rates vs. Exercising Muscle, and Na+/K+ Pumping Rates. Neurochem Res. 2020 Nov; 45(11):2607-2630.
    View in: PubMed
    Score: 0.624
  3. Dienel GA. The "protected" glucose transport through the astrocytic endoplasmic reticulum is too slow to serve as a quantitatively-important highway for nutrient delivery. J Neurosci Res. 2019 08; 97(8):854-862.
    View in: PubMed
    Score: 0.567
  4. Dienel GA. Brain Glucose Metabolism: Integration of Energetics with Function. Physiol Rev. 2019 01 01; 99(1):949-1045.
    View in: PubMed
    Score: 0.554
  5. Rothman DL, Dienel GA. Development of a Model to Test Whether Glycogenolysis Can Support Astrocytic Energy Demands of Na+, K+-ATPase and Glutamate-Glutamine Cycling, Sparing an Equivalent Amount of Glucose for Neurons. Adv Neurobiol. 2019; 23:385-433.
    View in: PubMed
    Score: 0.554
  6. Dienel GA. Metabolomic Assays of Postmortem Brain Extracts: Pitfalls in Extrapolation of Concentrations of Glucose and Amino Acids to Metabolic Dysregulation In Vivo in Neurological Diseases. Neurochem Res. 2019 Oct; 44(10):2239-2260.
    View in: PubMed
    Score: 0.540
  7. Dienel GA, Cruz NF, Sokoloff L, Driscoll BF. Determination of Glucose Utilization Rates in Cultured Astrocytes and Neurons with [14C]deoxyglucose: Progress, Pitfalls, and Discovery of Intracellular Glucose Compartmentation. Neurochem Res. 2017 Jan; 42(1):50-63.
    View in: PubMed
    Score: 0.435
  8. Dienel GA. The metabolic trinity, glucose-glycogen-lactate, links astrocytes and neurons in brain energetics, signaling, memory, and gene expression. Neurosci Lett. 2017 01 10; 637:18-25.
    View in: PubMed
    Score: 0.424
  9. Cruz NF, Ball KK, Froehner SC, Adams ME, Dienel GA. Regional registration of [6-(14)C]glucose metabolism during brain activation of a-syntrophin knockout mice. J Neurochem. 2013 Apr; 125(2):247-59.
    View in: PubMed
    Score: 0.370
  10. Ball KK, Cruz NF, Mrak RE, Dienel GA. Trafficking of glucose, lactate, and amyloid-beta from the inferior colliculus through perivascular routes. J Cereb Blood Flow Metab. 2010 Jan; 30(1):162-76.
    View in: PubMed
    Score: 0.292
  11. Gandhi GK, Cruz NF, Ball KK, Dienel GA. Astrocytes are poised for lactate trafficking and release from activated brain and for supply of glucose to neurons. J Neurochem. 2009 Oct; 111(2):522-36.
    View in: PubMed
    Score: 0.289
  12. Cruz NF, Ball KK, Dienel GA. Functional imaging of focal brain activation in conscious rats: impact of [(14)C]glucose metabolite spreading and release. J Neurosci Res. 2007 11 15; 85(15):3254-66.
    View in: PubMed
    Score: 0.256
  13. Ball KK, Gandhi GK, Thrash J, Cruz NF, Dienel GA. Astrocytic connexin distributions and rapid, extensive dye transfer via gap junctions in the inferior colliculus: implications for [(14)C]glucose metabolite trafficking. J Neurosci Res. 2007 Nov 15; 85(15):3267-83.
    View in: PubMed
    Score: 0.256
  14. Dienel GA, Ball KK, Cruz NF. A glycogen phosphorylase inhibitor selectively enhances local rates of glucose utilization in brain during sensory stimulation of conscious rats: implications for glycogen turnover. J Neurochem. 2007 Jul; 102(2):466-78.
    View in: PubMed
    Score: 0.246
  15. Dienel GA, Cruz NF. Astrocyte activation in working brain: energy supplied by minor substrates. Neurochem Int. 2006 May-Jun; 48(6-7):586-95.
    View in: PubMed
    Score: 0.228
  16. Trefz F, Frauendienst-Egger G, Dienel G, Cannet C, Schmidt-Mader B, Haas D, Blau N, Himmelreich N, Spraul M, Freisinger P, Dobrowolski S, Berg D, Pilotto A. Does hyperphenylalaninemia induce brain glucose hypometabolism? Cerebral spinal fluid findings in treated adult phenylketonuric patients. Mol Genet Metab. 2024 May; 142(1):108464.
    View in: PubMed
    Score: 0.199
  17. Dienel GA, Wang RY, Cruz NF. Generalized sensory stimulation of conscious rats increases labeling of oxidative pathways of glucose metabolism when the brain glucose-oxygen uptake ratio rises. J Cereb Blood Flow Metab. 2002 Dec; 22(12):1490-502.
    View in: PubMed
    Score: 0.182
  18. Dienel GA, Gillinder L, McGonigal A, Borges K. Potential new roles for glycogen in epilepsy. Epilepsia. 2023 01; 64(1):29-53.
    View in: PubMed
    Score: 0.181
  19. Hertz L, Dienel GA. Energy metabolism in the brain. Int Rev Neurobiol. 2002; 51:1-102.
    View in: PubMed
    Score: 0.170
  20. Dienel GA, Hertz L. Glucose and lactate metabolism during brain activation. J Neurosci Res. 2001 Dec 01; 66(5):824-38.
    View in: PubMed
    Score: 0.169
  21. Madsen PL, Cruz NF, Sokoloff L, Dienel GA. Cerebral oxygen/glucose ratio is low during sensory stimulation and rises above normal during recovery: excess glucose consumption during stimulation is not accounted for by lactate efflux from or accumulation in brain tissue. J Cereb Blood Flow Metab. 1999 Apr; 19(4):393-400.
    View in: PubMed
    Score: 0.141
  22. Dienel GA, Liu K, Popp D, Cruz NF. Enhanced acetate and glucose utilization during graded photic stimulation. Neuronal-glial interactions in vivo. Ann N Y Acad Sci. 1999; 893:279-81.
    View in: PubMed
    Score: 0.138
  23. Dienel GA, Cruz NF, Adachi K, Sokoloff L, Holden JE. Determination of local brain glucose level with [14C]methylglucose: effects of glucose supply and demand. Am J Physiol. 1997 11; 273(5):E839-49.
    View in: PubMed
    Score: 0.128
  24. Dienel GA. Lack of appropriate stoichiometry: Strong evidence against an energetically important astrocyte-neuron lactate shuttle in brain. J Neurosci Res. 2017 11; 95(11):2103-2125.
    View in: PubMed
    Score: 0.121
  25. Dienel GA, Rothman DL, Nordstr?m CH. Microdialysate concentration changes do not provide sufficient information to evaluate metabolic effects of lactate supplementation in brain-injured patients. J Cereb Blood Flow Metab. 2016 11; 36(11):1844-1864.
    View in: PubMed
    Score: 0.118
  26. Nakanishi H, Cruz NF, Adachi K, Sokoloff L, Dienel GA. Influence of glucose supply and demand on determination of brain glucose content with labeled methylglucose. J Cereb Blood Flow Metab. 1996 May; 16(3):439-49.
    View in: PubMed
    Score: 0.115
  27. Dienel GA, Cruz NF. Biochemical, Metabolic, and Behavioral Characteristics of Immature Chronic Hyperphenylalanemic Rats. Neurochem Res. 2016 Feb; 41(1-2):16-32.
    View in: PubMed
    Score: 0.109
  28. Adachi K, Cruz NF, Sokoloff L, Dienel GA. Labeling of metabolic pools by [6-14C]glucose during K(+)-induced stimulation of glucose utilization in rat brain. J Cereb Blood Flow Metab. 1995 Jan; 15(1):97-110.
    View in: PubMed
    Score: 0.105
  29. Wang RY, Dienel GA. Ion chromatography with suppressed conductivity detection: recoveries of 14C-labeled metabolites. Biotechniques. 1994 Jul; 17(1):106, 108, 110 passim.
    View in: PubMed
    Score: 0.101
  30. Dienel GA, Cruz NF. Contributions of glycogen to astrocytic energetics during brain activation. Metab Brain Dis. 2015 Feb; 30(1):281-98.
    View in: PubMed
    Score: 0.099
  31. Cruz NF, Dienel GA. Brain glucose levels in portacaval-shunted rats with chronic, moderate hyperammonemia: implications for determination of local cerebral glucose utilization. J Cereb Blood Flow Metab. 1994 Jan; 14(1):113-24.
    View in: PubMed
    Score: 0.098
  32. Mergenthaler P, Lindauer U, Dienel GA, Meisel A. Sugar for the brain: the role of glucose in physiological and pathological brain function. Trends Neurosci. 2013 Oct; 36(10):587-97.
    View in: PubMed
    Score: 0.095
  33. Dienel GA, Cruz NF. Synthesis of deoxyglucose-1-phosphate, deoxyglucose-1,6-bisphosphate, and other metabolites of 2-deoxy-D-[14C]glucose in rat brain in vivo: influence of time and tissue glucose level. J Neurochem. 1993 Jun; 60(6):2217-31.
    View in: PubMed
    Score: 0.094
  34. Dienel GA, Cruz NF, Sokoloff L. Metabolites of 2-deoxy-[14C]glucose in plasma and brain: influence on rate of glucose utilization determined with deoxyglucose method in rat brain. J Cereb Blood Flow Metab. 1993 Mar; 13(2):315-27.
    View in: PubMed
    Score: 0.092
  35. Dienel GA, Cruz NF, Nakanishi H, Melzer P, Moulis P, Sokoloff L. Comparison of rates of local cerebral glucose utilization determined with deoxy[1-14C]glucose and deoxy[6-14C]glucose. J Neurochem. 1992 Oct; 59(4):1430-6.
    View in: PubMed
    Score: 0.090
  36. Dienel GA. Fueling and imaging brain activation. ASN Neuro. 2012 Jul 20; 4(5).
    View in: PubMed
    Score: 0.089
  37. Dienel GA, Nelson T, Cruz NF, Jay T, Crane AM, Sokoloff L. Over-estimation of glucose-6-phosphatase activity in brain in vivo. Apparent difference in rates of [2-3H]glucose and [U-14C]glucose utilization is due to contamination of precursor pool with 14C-labeled products and incomplete recovery of 14C-labeled metabolites. J Biol Chem. 1988 Dec 25; 263(36):19697-708.
    View in: PubMed
    Score: 0.069
  38. Dienel GA, Cruz NF. Imaging brain activation: simple pictures of complex biology. Ann N Y Acad Sci. 2008 Dec; 1147:139-70.
    View in: PubMed
    Score: 0.069
  39. Dienel GA, Schmidt KC, Cruz NF. Astrocyte activation in vivo during graded photic stimulation. J Neurochem. 2007 Nov; 103(4):1506-22.
    View in: PubMed
    Score: 0.063
  40. Romanovsky D, Cruz NF, Dienel GA, Dobretsov M. Mechanical hyperalgesia correlates with insulin deficiency in normoglycemic streptozotocin-treated rats. Neurobiol Dis. 2006 Nov; 24(2):384-94.
    View in: PubMed
    Score: 0.059
  41. Hertz L, Peng L, Dienel GA. Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis. J Cereb Blood Flow Metab. 2007 Feb; 27(2):219-49.
    View in: PubMed
    Score: 0.058
  42. Theriault JE, Shaffer C, Dienel GA, Sander CY, Hooker JM, Dickerson BC, Barrett LF, Quigley KS. A functional account of stimulation-based aerobic glycolysis and its role in interpreting BOLD signal intensity increases in neuroimaging experiments. Neurosci Biobehav Rev. 2023 10; 153:105373.
    View in: PubMed
    Score: 0.048
  43. Cruz NF, Dienel GA. High glycogen levels in brains of rats with minimal environmental stimuli: implications for metabolic contributions of working astrocytes. J Cereb Blood Flow Metab. 2002 Dec; 22(12):1476-89.
    View in: PubMed
    Score: 0.045
  44. Rothman DL, Dienel GA, Behar KL, Hyder F, DiNuzzo M, Giove F, Mangia S. Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission. J Cereb Blood Flow Metab. 2022 05; 42(5):844-860.
    View in: PubMed
    Score: 0.043
  45. Cruz NF, Adachi K, Dienel GA. Rapid efflux of lactate from cerebral cortex during K+ -induced spreading cortical depression. J Cereb Blood Flow Metab. 1999 Apr; 19(4):380-92.
    View in: PubMed
    Score: 0.035
  46. Frerichs KU, Dienel GA, Cruz NF, Sokoloff L, Hallenbeck JM. Rates of glucose utilization in brain of active and hibernating ground squirrels. Am J Physiol. 1995 Feb; 268(2 Pt 2):R445-53.
    View in: PubMed
    Score: 0.026
  47. Dienel GA, Cruz NF, Mori K, Holden JE, Sokoloff L. Direct measurement of the lambda of the lumped constant of the deoxyglucose method in rat brain: determination of lambda and lumped constant from tissue glucose concentration or equilibrium brain/plasma distribution ratio for methylglucose. J Cereb Blood Flow Metab. 1991 Jan; 11(1):25-34.
    View in: PubMed
    Score: 0.020
  48. Dienel GA, Cruz NF, Mori K, Sokoloff L. Acid lability of metabolites of 2-deoxyglucose in rat brain: implications for estimates of kinetic parameters of deoxyglucose phosphorylation and transport between blood and brain. J Neurochem. 1990 Apr; 54(4):1440-8.
    View in: PubMed
    Score: 0.019
  49. Mori K, Cruz N, Dienel G, Nelson T, Sokoloff L. Direct chemical measurement of the lambda of the lumped constant of the [14C]deoxyglucose method in rat brain: effects of arterial plasma glucose level on the distribution spaces of [14C]deoxyglucose and glucose and on lambda. J Cereb Blood Flow Metab. 1989 Jun; 9(3):304-14.
    View in: PubMed
    Score: 0.018
  50. Nelson T, Lucignani G, Atlas S, Crane AM, Dienel GA, Sokoloff L. Reexamination of glucose-6-phosphatase activity in the brain in vivo: no evidence for a futile cycle. Science. 1985 Jul 05; 229(4708):60-2.
    View in: PubMed
    Score: 0.003
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