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A peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment.
Alagpulinsa DA, Yaccoby S, Ayyadevara S, Shmookler Reis RJ. A peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment. Cancer Biol Ther. 2015; 16(6):976-86.
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PubMed
subject areas
Animals
Antineoplastic Agents
Cell Line, Tumor
Disease Models, Animal
DNA Damage
Drug Resistance, Neoplasm
Gene Expression Regulation, Neoplastic
Genes, BRCA1
Humans
Melphalan
Mice
Multiple Myeloma
Peptide Nucleic Acids
Rad51 Recombinase
S Phase
Transcription, Genetic
Xenograft Model Antitumor Assays
authors with profiles
Shmuel Yaccoby
Robert Reis
Srinivas Ayyadevara